Lista de obras - Rui M. Brito - Dominio Público Uruguay

"Structural characterization of the minimal segment of TDP-43 competent for aggregation".

artículo científico

A New Folding Kinetic Mechanism for Human Transthyretin and the Influence of the Amyloidogenic V30M Mutation.

artículo científico publicado en 2016

A look into amyloid formation by transthyretin: aggregation pathway and a novel kinetic model.

artículo científico publicado en 2015

A novel bis-furan scaffold for transthyretin stabilization and amyloid inhibition

scholarly article by Carlos J.V. Simões et al published October 2016 in European Journal of Medicinal Chemistry

A serpin released by an entomopathogen impairs clot formation in insect defense system

artículo científico publicado en 2013

A structural model of an amyloid protofilament of transthyretin.

artículo científico publicado en 2005

Assessing the Effect of 2D Fingerprint Filtering on ILP-Based Structure-Activity Relationships Toxicity Studies in Drug Design

article

Biological activity of heterologous murine interleukin-10 and preliminary studies on the use of a dextrin nanogel as a delivery system ⬇️

artículo científico publicado el 9 de septiembre de 2010

Biophysical characterization of laforin-carbohydrate interaction.

artículo científico publicado en 2015

Changes in channel trafficking and protein stability caused by LQT2 mutations in the PAS domain of the HERG channel

artículo científico publicado en 2012

Comparative NMR studies on cardiac troponin C and a mutant incapable of binding calcium at site II.

artículo científico publicado en 1991

Comparative Study of Classification Algorithms Using Molecular Descriptors in Toxicological DataBases

scholarly article by Max Pereira et al published 2009 in Lecture Notes in Computer Science

Comparative calorimetric study of non-amyloidogenic and amyloidogenic variants of the homotetrameric protein transthyretin

scientific article published on 01 December 2000

Conformation study of HA(306-318) antigenic peptide of the haemagglutinin influenza virus protein.

artículo científico publicado en 2006

Effect of ethyleneoxide groups of anionic surfactants on lipase activity

artículo científico publicado en 2016

Evaluation by fluorescence, STD-NMR, docking and semi-empirical calculations of the o-NBA photo-acid interaction with BSA.

artículo científico publicado en 2016

FH8--a small EF-hand protein from Fasciola hepatica.

artículo científico publicado en 2010

Functional and conformational changes in the aspartic protease cardosin A induced by TFE

artículo científico publicado en 2012

Grid Computing Solutions for Distributed Repositories of Protein Folding and Unfolding Simulations

artículo científico publicado en 2008

Hereditary nonspherocytic hemolytic anemia caused by red cell glucose-6-phosphate isomerase (GPI) deficiency in two Portuguese patients: Clinical features and molecular study

artículo científico publicado en 2016

In situ ultra-fast heat deposition does not perturb the structure of serum albumin.

artículo científico publicado en 2016

Lead optimization of resilient next-generation transthyretin stabilizers for multiple target-product profiles: approaching the CNS

artículo científico publicado en 2019

Ligand-Targeted Delivery of Photosensitizers for Cancer Treatment

scientific article published on 14 November 2020

Modeling of the Toll-like receptor 3 and a putative Toll-like receptor 3 antagonist encoded by the African swine fever virus.

artículo científico publicado en 2011

Oligomerization Profile of Human Transthyretin Variants with Distinct Amyloidogenicity

artículo científico publicado en 2020

On Mining Protein Unfolding Simulation Data with Inductive Logic Programming

One Peptide Reveals the Two Faces of α-Helix Unfolding-Folding Dynamics.

artículo científico publicado en 2018

P-found: Grid-enabling distributed repositories of protein folding and unfolding simulations for data mining

Predicting hydrophobic solvation by molecular simulation: 1. Testing united-atom alkane models.

artículo científico publicado en 2017

Solution structures of the C-terminal domain of cardiac troponin C free and bound to the N-terminal domain of cardiac troponin I

artículo científico publicado en 1999

Spatial Clustering of Molecular Dynamics Trajectories in Protein Unfolding Simulations

Structure and Aggregation Mechanisms in Amyloids

scientific article published on 06 March 2020

Targeting transthyretin amyloidosis in the eye with next-generation stabilizers: AT40 displays potent TTR stabilization in the human vitreous

artículo científico publicado en 2019

Tetramer Dissociation and Monomer Partial Unfolding Precedes Protofibril Formation in Amyloidogenic Transthyretin Variants

artículo científico publicado en 2001

The Central Role of Non-Structural Protein 1 (NS1) in Influenza Biology and Infection

artículo científico publicado en 2020

The Tetrameric Protein Transthyretin Dissociates to a Non-native Monomer in Solution

scientific article published in Journal of Biological Chemistry

The V30M Amyloidogenic Mutation Decreases the Rate of Refolding Kinetics of the Tetrameric Protein Transthyretin

article published in 2012

The amyloidogenic potential of transthyretin variants correlates with their tendency to aggregate in solution

artículo científico publicado en 1997

The apoptogenic toxin AIP56 is a metalloprotease A-B toxin that cleaves NF-κb P65

artículo científico publicado en 2013

The saposin-like domain of the plant aspartic proteinase precursor is a potent inducer of vesicle leakage.

artículo científico publicado en 2000

To hit or not to hit: Large-scale sequence analysis and structure characterization of influenza A NS1 unlocks new antiviral target potential

scientific article published on 27 April 2019

Toward the discovery of functional transthyretin amyloid inhibitors: application of virtual screening methods.

artículo científico publicado en 2010

VEGF-Functionalized Dextran Has Longer Intracellular Bioactivity than VEGF in Endothelial Cells

artículo científico publicado en 2012

Lista de obras de Rui M. Brito

"Structural characterization of the minimal segment of TDP-43 competent for aggregation".

A New Folding Kinetic Mechanism for Human Transthyretin and the Influence of the Amyloidogenic V30M Mutation.

A look into amyloid formation by transthyretin: aggregation pathway and a novel kinetic model.

A novel bis-furan scaffold for transthyretin stabilization and amyloid inhibition

A serpin released by an entomopathogen impairs clot formation in insect defense system

A structural model of an amyloid protofilament of transthyretin.

Assessing the Effect of 2D Fingerprint Filtering on ILP-Based Structure-Activity Relationships Toxicity Studies in Drug Design

Biological activity of heterologous murine interleukin-10 and preliminary studies on the use of a dextrin nanogel as a delivery system ⬇️

Biophysical characterization of laforin-carbohydrate interaction.

Changes in channel trafficking and protein stability caused by LQT2 mutations in the PAS domain of the HERG channel

Comparative NMR studies on cardiac troponin C and a mutant incapable of binding calcium at site II.

Comparative Study of Classification Algorithms Using Molecular Descriptors in Toxicological DataBases

Comparative calorimetric study of non-amyloidogenic and amyloidogenic variants of the homotetrameric protein transthyretin

Conformation study of HA(306-318) antigenic peptide of the haemagglutinin influenza virus protein.

Effect of ethyleneoxide groups of anionic surfactants on lipase activity

Evaluation by fluorescence, STD-NMR, docking and semi-empirical calculations of the o-NBA photo-acid interaction with BSA.

FH8--a small EF-hand protein from Fasciola hepatica.

Functional and conformational changes in the aspartic protease cardosin A induced by TFE

Grid Computing Solutions for Distributed Repositories of Protein Folding and Unfolding Simulations

Hereditary nonspherocytic hemolytic anemia caused by red cell glucose-6-phosphate isomerase (GPI) deficiency in two Portuguese patients: Clinical features and molecular study

In situ ultra-fast heat deposition does not perturb the structure of serum albumin.

Lead optimization of resilient next-generation transthyretin stabilizers for multiple target-product profiles: approaching the CNS

Ligand-Targeted Delivery of Photosensitizers for Cancer Treatment

Modeling of the Toll-like receptor 3 and a putative Toll-like receptor 3 antagonist encoded by the African swine fever virus.

Oligomerization Profile of Human Transthyretin Variants with Distinct Amyloidogenicity

On Mining Protein Unfolding Simulation Data with Inductive Logic Programming

One Peptide Reveals the Two Faces of α-Helix Unfolding-Folding Dynamics.

P-found: Grid-enabling distributed repositories of protein folding and unfolding simulations for data mining

Predicting hydrophobic solvation by molecular simulation: 1. Testing united-atom alkane models.

Solution structures of the C-terminal domain of cardiac troponin C free and bound to the N-terminal domain of cardiac troponin I

Spatial Clustering of Molecular Dynamics Trajectories in Protein Unfolding Simulations

Structure and Aggregation Mechanisms in Amyloids

Targeting transthyretin amyloidosis in the eye with next-generation stabilizers: AT40 displays potent TTR stabilization in the human vitreous

Tetramer Dissociation and Monomer Partial Unfolding Precedes Protofibril Formation in Amyloidogenic Transthyretin Variants

The Central Role of Non-Structural Protein 1 (NS1) in Influenza Biology and Infection

The Tetrameric Protein Transthyretin Dissociates to a Non-native Monomer in Solution

The V30M Amyloidogenic Mutation Decreases the Rate of Refolding Kinetics of the Tetrameric Protein Transthyretin

The amyloidogenic potential of transthyretin variants correlates with their tendency to aggregate in solution

The apoptogenic toxin AIP56 is a metalloprotease A-B toxin that cleaves NF-κb P65

The saposin-like domain of the plant aspartic proteinase precursor is a potent inducer of vesicle leakage.

To hit or not to hit: Large-scale sequence analysis and structure characterization of influenza A NS1 unlocks new antiviral target potential

Toward the discovery of functional transthyretin amyloid inhibitors: application of virtual screening methods.

VEGF-Functionalized Dextran Has Longer Intracellular Bioactivity than VEGF in Endothelial Cells