Lista de obras - Johnny X Huang - Dominio Público Uruguay

A new antibiotic with potent activity targets MscL.

artículo científico publicado en 2015

Activity and Predicted Nephrotoxicity of Synthetic Antibiotics Based on Polymyxin B.

artículo científico publicado en 2016

An "Unlikely" Pair: The Antimicrobial Synergy of Polymyxin B in Combination with the Cystic Fibrosis Transmembrane Conductance Regulator Drugs KALYDECO and ORKAMBI.

artículo científico publicado en 2016

An amphipathic peptide with antibiotic activity against multidrug-resistant Gram-negative bacteria

artículo científico publicado en 2020

An azido-oxazolidinone antibiotic for live bacterial cell imaging and generation of antibiotic variants

artículo científico publicado en 2014

Antibacterial Low Molecular Weight Cationic Polymers: Dissecting the Contribution of Hydrophobicity, Chain Length and Charge to Activity

artículo científico publicado en 2016

Antibacterial and antifungal screening of natural products sourced from Australian fungi and characterisation of pestalactams D-F.

artículo científico publicado en 2015

Carbohydrate scaffolds as glycosyltransferase inhibitors with in vivo antibacterial activity

artículo científico publicado en 2015

Cationic Acrylate Oligomers Comprising Amino Acid Mimic Moieties Demonstrate Improved Antibacterial Killing Efficiency.

artículo científico publicado en 2016

Cell- and biomarker-based assays for predicting nephrotoxicity

artículo científico publicado en 2014

Development of anti-infectives using phage display: biological agents against bacteria, viruses, and parasites.

artículo científico publicado en 2012

Discovery of novel pneumococcal surface antigen A (PsaA) inhibitors using a fragment-based drug design approach

artículo científico publicado en 2015

Drug-binding energetics of human α-1-acid glycoprotein assessed by isothermal titration calorimetry and molecular docking simulations.

artículo científico publicado en 2012

Drug-drug plasma protein binding interactions of ivacaftor

artículo científico publicado en 2015

Efficient synthesis of anacardic acid analogues and their antibacterial activities.

artículo científico publicado en 2013

Evaluation of biomarkers for in vitro prediction of drug-induced nephrotoxicity: comparison of HK-2, immortalized human proximal tubule epithelial, and primary cultures of human proximal tubular cells

artículo científico publicado en 2015

Flemingin-Type Prenylated Chalcones from the Sarawak Rainforest Plant Desmodium congestum

artículo científico publicado en 2015

Genome-Wide Off-Target Analysis in CRISPR-Cas9 Modified Mice and Their Offspring

scientific article published on 05 November 2019

Identification of antitubercular benzothiazinone compounds by ligand-based design

artículo científico publicado en 2012

Molecular Characterisation of the Haemagglutinin Glycan-Binding Specificity of Egg-Adapted Vaccine Strains of the Pandemic 2009 H1N1 Swine Influenza A Virus.

artículo científico publicado en 2015

Molecular Characterization of Lipopolysaccharide Binding to Human α-1-Acid Glycoprotein

artículo científico publicado en 2012

Molecular basis for the increased polymyxin susceptibility of Klebsiella pneumoniae strains with under-acylated lipid A.

artículo científico publicado en 2012

Mucin Binding Reduces Colistin Antimicrobial Activity.

artículo científico publicado en 2015

Plasma Protein Binding Structure-Activity Relationships Related to the N-Terminus of Daptomycin.

artículo científico publicado en 2017

Programmed Death-1 Ligand 2-Mediated Regulation of the PD-L1 to PD-1 Axis Is Essential for Establishing CD4(+) T Cell Immunity

artículo científico publicado en 2016

Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteria.

artículo científico publicado en 2018

Ramoplanin at bactericidal concentrations induces bacterial membrane depolarization in Staphylococcus aureus

artículo científico publicado en 2014

Structure aided design of chimeric antibiotics

article by Tomislav Karoli et al published April 2012 in Bioorganic & Medicinal Chemistry Letters

Structure, Function, and Biosynthetic Origin of Octapeptin Antibiotics Active against Extensively Drug-Resistant Gram-Negative Bacteria.

artículo científico publicado en 2018

Structure-Function Studies of Polymyxin B Lipononapeptides

artículo científico publicado en 2019

Structure-activity relationships for the binding of polymyxins with human α-1-acid glycoprotein

artículo científico publicado en 2012

Surface changes and polymyxin interactions with a resistant strain of Klebsiella pneumoniae.

artículo científico publicado en 2013

Synthesis and evaluation of cationic norbornanes as peptidomimetic antibacterial agents

artículo científico publicado en 2015

Synthesis of Norbornane Bisether Antibiotics via Silver-mediated Alkylation

artículo científico publicado en 2015

Synthesis of essramycin and comparison of its antibacterial activity

artículo científico publicado en 2010

Synthesis of octapeptin C4 and biological profiling against NDM-1 and polymyxin-resistant bacteria.

artículo científico publicado en 2017

The Plasma Protein Binding Proteome of Ertapenem: A Novel Compound-Centric Proteomic Approach for Elucidating Drug-Plasma Protein Binding Interactions.

artículo científico publicado en 2016

The diagnostic sensitivity of dengue rapid test assays is significantly enhanced by using a combined antigen and antibody testing approach

artículo científico publicado en 2011

Truncated Latrunculins as Actin Inhibitors Targeting Plasmodium falciparum Motility and Host Cell Invasion.

artículo científico publicado en 2016

α-Conotoxin dendrimers have enhanced potency and selectivity for homomeric nicotinic acetylcholine receptors.

artículo científico publicado en 2015

Lista de obras de Johnny X Huang

A new antibiotic with potent activity targets MscL.

Activity and Predicted Nephrotoxicity of Synthetic Antibiotics Based on Polymyxin B.

An "Unlikely" Pair: The Antimicrobial Synergy of Polymyxin B in Combination with the Cystic Fibrosis Transmembrane Conductance Regulator Drugs KALYDECO and ORKAMBI.

An amphipathic peptide with antibiotic activity against multidrug-resistant Gram-negative bacteria

An azido-oxazolidinone antibiotic for live bacterial cell imaging and generation of antibiotic variants

Antibacterial Low Molecular Weight Cationic Polymers: Dissecting the Contribution of Hydrophobicity, Chain Length and Charge to Activity

Antibacterial and antifungal screening of natural products sourced from Australian fungi and characterisation of pestalactams D-F.

Carbohydrate scaffolds as glycosyltransferase inhibitors with in vivo antibacterial activity

Cationic Acrylate Oligomers Comprising Amino Acid Mimic Moieties Demonstrate Improved Antibacterial Killing Efficiency.

Cell- and biomarker-based assays for predicting nephrotoxicity

Development of anti-infectives using phage display: biological agents against bacteria, viruses, and parasites.

Discovery of novel pneumococcal surface antigen A (PsaA) inhibitors using a fragment-based drug design approach

Drug-binding energetics of human α-1-acid glycoprotein assessed by isothermal titration calorimetry and molecular docking simulations.

Drug-drug plasma protein binding interactions of ivacaftor

Efficient synthesis of anacardic acid analogues and their antibacterial activities.

Evaluation of biomarkers for in vitro prediction of drug-induced nephrotoxicity: comparison of HK-2, immortalized human proximal tubule epithelial, and primary cultures of human proximal tubular cells

Flemingin-Type Prenylated Chalcones from the Sarawak Rainforest Plant Desmodium congestum

Genome-Wide Off-Target Analysis in CRISPR-Cas9 Modified Mice and Their Offspring

Identification of antitubercular benzothiazinone compounds by ligand-based design

Molecular Characterisation of the Haemagglutinin Glycan-Binding Specificity of Egg-Adapted Vaccine Strains of the Pandemic 2009 H1N1 Swine Influenza A Virus.

Molecular Characterization of Lipopolysaccharide Binding to Human α-1-Acid Glycoprotein

Molecular basis for the increased polymyxin susceptibility of Klebsiella pneumoniae strains with under-acylated lipid A.

Mucin Binding Reduces Colistin Antimicrobial Activity.

Plasma Protein Binding Structure-Activity Relationships Related to the N-Terminus of Daptomycin.

Programmed Death-1 Ligand 2-Mediated Regulation of the PD-L1 to PD-1 Axis Is Essential for Establishing CD4(+) T Cell Immunity

Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteria.

Ramoplanin at bactericidal concentrations induces bacterial membrane depolarization in Staphylococcus aureus

Structure aided design of chimeric antibiotics

Structure, Function, and Biosynthetic Origin of Octapeptin Antibiotics Active against Extensively Drug-Resistant Gram-Negative Bacteria.

Structure-Function Studies of Polymyxin B Lipononapeptides

Structure-activity relationships for the binding of polymyxins with human α-1-acid glycoprotein

Surface changes and polymyxin interactions with a resistant strain of Klebsiella pneumoniae.

Synthesis and evaluation of cationic norbornanes as peptidomimetic antibacterial agents

Synthesis of Norbornane Bisether Antibiotics via Silver-mediated Alkylation

Synthesis of essramycin and comparison of its antibacterial activity

Synthesis of octapeptin C4 and biological profiling against NDM-1 and polymyxin-resistant bacteria.

The Plasma Protein Binding Proteome of Ertapenem: A Novel Compound-Centric Proteomic Approach for Elucidating Drug-Plasma Protein Binding Interactions.

The diagnostic sensitivity of dengue rapid test assays is significantly enhanced by using a combined antigen and antibody testing approach

Truncated Latrunculins as Actin Inhibitors Targeting Plasmodium falciparum Motility and Host Cell Invasion.

α-Conotoxin dendrimers have enhanced potency and selectivity for homomeric nicotinic acetylcholine receptors.