Lista de obras - Kazuhisa Nakayama - Dominio Público Uruguay

A mutation of furin causes the lack of precursor-processing activity in human colon carcinoma LoVo cells

artículo científico publicado en 1993

A second mutant allele of furin in the processing-incompetent cell line, LoVo. Evidence for involvement of the homo B domain in autocatalytic activation.

artículo científico publicado en 1995

ADP-ribosylation factor-1 is sensitive to N-ethylmaleimide.

artículo científico publicado en 1998

AMY-1 (associate of Myc-1) localization to the trans-Golgi network through interacting with BIG2, a guanine-nucleotide exchange factor for ADP-ribosylation factors

artículo científico publicado en 2006

ARF1 and ARF3 are required for the integrity of recycling endosomes and the recycling pathway

artículo científico publicado en 2012

ARF1 and ARF4 regulate recycling endosomal morphology and retrograde transport from endosomes to the Golgi apparatus ⬇️

artículo científico publicado el 19 de junio de 2013

ATP11C mutation is responsible for the defect in phosphatidylserine uptake in UPS-1 cells.

artículo científico publicado en 2015

ATP9B, a P4-ATPase (a putative aminophospholipid translocase), localizes to the trans-Golgi network in a CDC50 protein-independent manner

artículo científico publicado en 2011

ATP9B, a P4-ATPase (a putative aminophospholipid translocase), localizes to the trans-Golgi network in a CDC50 protein-independent manner.

artículo científico publicado en 2015

Activation of histidine decarboxylase through post-translational cleavage by caspase-9 in a mouse mastocytoma P-815.

artículo científico publicado en 2007

Adaptor gamma ear homology domain conserved in gamma-adaptin and GGA proteins that interact with gamma-synergin

artículo científico publicado en 2000

Alteration of transbilayer phospholipid compositions is involved in cell adhesion, cell spreading, and focal adhesion formation.

artículo científico publicado en 2016

Anterograde trafficking of ciliary MAP kinase-like ICK/CILK1 by the IFT machinery is required for intraciliary retrograde protein trafficking

scientific article published on 29 July 2020

Architecture of the IFT ciliary trafficking machinery and interplay between its components

artículo científico publicado en 2020

Architectures of multisubunit complexes revealed by a visible immunoprecipitation assay using fluorescent fusion proteins

artículo científico publicado en 2015

Arfaptins are localized to the trans-Golgi by interaction with Arl1, but not Arfs.

artículo científico publicado en 2011

BBS1 is involved in retrograde trafficking of ciliary GPCRs in the context of the BBSome complex

artículo científico publicado en 2018

BIG2, a guanine nucleotide exchange factor for ADP-ribosylation factors: its localization to recycling endosomes and implication in the endosome integrity

artículo científico publicado en 2004

C11ORF74 interacts with the IFT-A complex and participates in ciliary BBSome localization

scientific article published on 01 March 2019

COPI-mediated retrieval of SCAP is crucial for regulating lipogenesis under basal and sterol-deficient conditions

artículo científico publicado en 2015

Cellular and subcellular localization of EFA6C, a third member of the EFA6 family, in adult mouse Purkinje cells

scientific journal article

Ciliary entry of KIF17 is dependent on its binding to the IFT-B complex via IFT46-IFT56 as well as on its nuclear localization signal.

artículo científico publicado en 2017

Ciliary protein trafficking mediated by IFT and BBSome complexes with the aid of kinesin-2 and dynein-2 motors.

artículo científico publicado en 2017

Ciliopathy-associated mutations of IFT122 impair ciliary protein trafficking but not ciliogenesis

artículo científico publicado en 2017

Class I Arfs (Arf1 and Arf3) and Arf6 are localized to the Flemming body and play important roles in cytokinesis.

artículo científico publicado en 2015

Cloning and Functional Expression of a Novel Endoprotease Involved in Prohormone Processing at Dibasic Sites1 ⬇️

artículo científico publicado el 1 de junio de 1991

Convergence of cell cycle regulation and growth factor signals on GRASP65

artículo científico publicado en 2005

Differential effects of depletion of ARL1 and ARFRP1 on membrane trafficking between the trans-Golgi network and endosomes

artículo científico publicado en 2009

Distinct roles of Rab11 and Arf6 in the regulation of Rab11-FIP3/arfophilin-1 localization in mitotic cells.

artículo científico publicado en 2011

Dominant-negative mutant of BIG2, an ARF-guanine nucleotide exchange factor, specifically affects membrane trafficking from the trans-Golgi network through inhibiting membrane association of AP-1 and GGA coat proteins

artículo científico publicado en 2002

Dual control of membrane targeting by PtdIns(4)P and ARF

scientific article published on 01 October 2004

Dynamin II is involved in endocytosis but not in the formation of transport vesicles from the trans-Golgi network

artículo científico publicado en 1999

EFA6 activates Arf6 and participates in its targeting to the Flemming body during cytokinesis.

artículo científico publicado en 2013

Effects of propeptide deletion on human renin secretion from mouse pituitary AtT-20 cells.

artículo científico publicado en 1990

Establishment of the culture model system that reflects the process of terminal differentiation of connective tissue-type mast cells.

artículo científico publicado en 2008

Expression of BIG2 and analysis of its function in mammalian cells

artículo científico publicado en 2005

Expression of the mouse macrophage cystine transporter in Xenopus laevis oocytes

artículo científico publicado en 1991

Functional cross-talk between Rab14 and Rab4 through a dual effector, RUFY1/Rabip4.

artículo científico publicado en 2010

Functional involvement of TMF/ARA160 in Rab6-dependent retrograde membrane traffic.

artículo científico publicado en 2007

Furin has the proalbumin substrate specificity and serpin inhibitory properties of an in situ hepatic convertase

scientific article published on 01 January 1994

Furin: a mammalian subtilisin/Kex2p-like endoprotease involved in processing of a wide variety of precursor proteins

artículo científico publicado en 1997

GAT (GGA and Tom1) domain responsible for ubiquitin binding and ubiquitination.

artículo científico publicado en 2003

GBF1-Arf-COPI-ArfGAP-mediated Golgi-to-ER transport involved in regulation of lipid homeostasis

artículo científico publicado en 2011

GGA proteins associate with Golgi membranes through interaction between their GGAH domains and ADP-ribosylation factors

artículo científico publicado en 2002

GM130 is a parallel tetramer with a flexible rod-like structure and N-terminally open (Y-shaped) and closed (I-shaped) conformations

scientific journal article

Gamma-adaptin interacts directly with Rabaptin-5 through its ear domain.

artículo científico publicado en 2002

Guanine nucleotide-exchange factors for arf GTPases: their diverse functions in membrane traffic.

artículo científico publicado en 2004

Histamine synthesis is required for granule maturation in murine mast cells.

artículo científico publicado en 2013

Identification and Characterization of Novel Clathrin Adaptor-related Proteins ⬇️

artículo científico publicado el 18 de septiembre de 1998

Identification and Subcellular Localization of a Novel Mammalian Dynamin-Related Protein Homologous to Yeast Vps1p and Dnm1p ⬇️

artículo científico publicado el 1 de septiembre de 1997

Identification and functional expression of a new member of the mammalian Kex2-like processing endoprotease family: its striking structural similarity to PACE4

scientific journal article

Identification of a five-pass transmembrane protein family localizing in the Golgi apparatus and the ER.

artículo científico publicado en 2003

Immunocytochemical localization of prohormone convertases PC1/PC3 and PC2 in rat pancreatic islets

artículo científico publicado en 1996

Interaction of WDR60 intermediate chain with TCTEX1D2 light chain of the dynein-2 complex is crucial for ciliary protein trafficking

scientific article published on 09 May 2018

Interaction of heterotrimeric kinesin-II with IFT-B-connecting tetramer is crucial for ciliogenesis

scientific article published on 14 June 2018

Interactions of the dynein-2 intermediate chain WDR34 with the light chains are required for ciliary retrograde protein trafficking

scientific article published on 16 January 2019

Interleukin-1 and lipopolysaccharide enhance intercellular adhesion molecule-1 expression in cell lines of human squamous cell carcinoma

scientific article published on 01 February 1997

Intermolecular and interdomain interactions of a dynamin-related GTP-binding protein, Dnm1p/Vps1p-like protein

scientific article published on 01 January 1999

Intraflagellar transport-A complex mediates ciliary entry and retrograde trafficking of ciliary G protein-coupled receptors.

artículo científico publicado en 2016

Involvement of CD44 in mast cell proliferation during terminal differentiation

artículo científico publicado en 2009

Localization of Kex2-like processing endoproteases, furin and PC4, within mouse testis by in situ hybridization

scientific article published on 01 January 1993

Localization of furin to the trans-Golgi network and recycling from the cell surface involves Ser and Tyr residues within the cytoplasmic domain.

artículo científico publicado en 1995

Mechanisms of membrane curvature generation in membrane traffic.

artículo científico publicado en 2012

Membrane orientation of the precursor 74-kDa form of L-histidine decarboxylase.

artículo científico publicado en 2006

Membrane recruitment of effector proteins by Arf and Rab GTPases.

artículo científico publicado en 2005

Mitosis-Coupled, Microtubule-Dependent Clustering of Endosomal Vesicles around Centrosomes ⬇️

artículo científico publicado el 16 de enero de 2013

Modulation of primary cilia length by melanin-concentrating hormone receptor 1.

artículo científico publicado en 2016

Molecular and enzymatic properties of furin, a Kex2-like endoprotease involved in precursor cleavage at Arg-X-Lys/Arg-Arg sites.

artículo científico publicado en 1992

Molecular mechanism of membrane recruitment of GGA by ARF in lysosomal protein transport

artículo científico publicado en 2003

Overall Architecture of the Intraflagellar Transport (IFT)-B Complex Containing Cluap1/IFT38 as an Essential Component of the IFT-B Peripheral Subcomplex

artículo científico publicado en 2016

Overexpression of an ADP-ribosylation Factor-Guanine Nucleotide Exchange Factor, BIG2, Uncouples Brefeldin A-induced Adaptor Protein-1 Coat Dissociation and Membrane Tubulation ⬇️

artículo científico publicado el 2 de enero de 2002

Phospholipid Flippase ATP10A Translocates Phosphatidylcholine and Is Involved in Plasma Membrane Dynamics

artículo científico publicado en 2015

Phospholipid flippase ATP11C is endocytosed and downregulated following Ca2+-mediated protein kinase C activation.

artículo científico publicado en 2017

Phospholipid flippase activities and substrate specificities of human type IV P-type ATPases localized to the plasma membrane

artículo científico publicado en 2014

Phospholipid-flipping activity of P4-ATPase drives membrane curvature

article published in 2018

Positional and additive effects of basic amino acids on processing of precursor proteins within the constitutive secretory pathway

artículo científico publicado en 1993

Practical method for targeted disruption of cilia-related genes by using CRISPR/Cas9-mediated, homology-independent knock-in system

artículo científico publicado en 2017

Predominant expression of the short form of GGA3 in human cell lines and tissues.

artículo científico publicado en 2003

Processing of wild-type and mutant proinsulin-like growth factor-IA by subtilisin-related proprotein convertases.

artículo científico publicado en 1997

Proprotein processing activity and cleavage site selectivity of the Kex2-like endoprotease PACE4

scientific article published on 01 December 1993

Prorenin is sorted into the regulated secretory pathway independent of its processing to renin in mouse pituitary AtT-20 cells

scientific article published on 01 October 1989

Proteolytic processing of pro-opiomelanocortin occurs in acidifying secretory granules of AtT-20 cells.

artículo científico publicado en 1997

Proteolytic processing of the hepatocyte growth factor/scatter factor receptor by furin

scientific article published on 01 August 1993

Purification and properties of extracellular poly(3-hydroxybutyrate) depolymerases from Pseudomonas lemoignei

scientific article published on 01 January 1985

Purification of recombinant soluble forms of furin produced in Chinese hamster ovary cells

scientific article published on 01 January 1994

RABL2 interacts with the intraflagellar transport-B complex and CEP19 and participates in ciliary assembly.

artículo científico publicado en 2017

Rab11 regulates exocytosis of recycling vesicles at the plasma membrane.

artículo científico publicado en 2012

Recruitment of Tom1L1/Srcasm to endosomes and the midbody by Tsg101.

artículo científico publicado en 2008

Recruitment of clathrin onto endosomes by the Tom1-Tollip complex

artículo científico publicado en 2006

Redundant roles of BIG2 and BIG1, guanine-nucleotide exchange factors for ADP-ribosylation factors in membrane traffic between the trans-Golgi network and endosomes

artículo científico

Regulation of ciliary retrograde protein trafficking by the Joubert syndrome proteins ARL13B and INPP5E.

artículo científico publicado en 2016

Regulation of cytokinesis by membrane trafficking involving small GTPases and the ESCRT machinery

artículo científico

Regulation of phosphatidylinositol 4-phosphate 5-kinase activity by partner proteins.

artículo científico publicado en 2007

Requirement of IFT-B-BBSome complex interaction in export of GPR161 from cilia

scientific article published on 17 September 2019

Restriction of mast cell proliferation through hyaluronan synthesis by co-cultured fibroblasts.

artículo científico publicado en 2012

Retroendocytosis pathway of ABCA1/apoA-I contributes to HDL formation.

artículo científico publicado en 2008

Robust interaction of IFT70 with IFT52-IFT88 in the IFT-B complex is required for ciliogenesis

artículo científico publicado en 2018

Role of ADP-ribosylation factor 6 (ARF6) in gastric acid secretion

artículo científico publicado en 2003

Role of cathepsin B as prorenin processing enzyme in human kidney

scientific article published on 01 June 1995

SNAP23/25 and VAMP2 mediate exocytic event of transferrin receptor-containing recycling vesicles.

artículo científico publicado en 2015

Sequence requirements for endoproteolytic processing of precursor proteins by furin: transfection and in vitro experiments.

artículo científico publicado en 1994

Shigella Targets Epithelial Tricellular Junctions and Uses a Noncanonical Clathrin-Dependent Endocytic Pathway to Spread Between Cells ⬇️

artículo científico publicado el 19 de abril de 2012

Similar subunit interactions contribute to assembly of clathrin adaptor complexes and COPI complex: analysis using yeast three-hybrid system

artículo científico publicado en 2001

Strain-specific presence of two TGN38 isoforms and absence of TGN41 in mouse.

artículo científico publicado en 1995

Structural basis for Arf6-MKLP1 complex formation on the Flemming body responsible for cytokinesis.

artículo científico publicado en 2012

Structural basis for recognition of acidic-cluster dileucine sequence by GGA1

artículo científico publicado en 2002

Structural basis for recognition of ubiquitinated cargo by Tom1-GAT domain

artículo científico publicado en 2005

Structure determination of GGA-GAE and gamma1-ear in complex with peptides: crystallization of low-affinity complexes in membrane traffic

artículo científico publicado en 2005

Structure of the rat renin gene

scientific journal article

Subtype-specific trafficking of endothelin receptors

scientific article published on 01 March 2000

Testis-Specific Prohormone Convertase PC4 Processes the Precursor of Pituitary Adenylate Cyclase-activating Polypeptide (PACAP) ⬇️

artículo científico publicado el 1 de enero de 1998

The cytoplasmic C-terminal region of the ATP11C variant determines its localization at the polarized plasma membrane

scientific article published on 02 September 2019

The influence of glycosylation on the fate of renin expressed in Xenopus oocytes

scientific article published on 01 July 1990

The isoforms of proprotein convertase PC5 are sorted to different subcellular compartments

artículo científico publicado en 1996

The phospholipid flippase ATP9A is required for the recycling pathway from the endosomes to the plasma membrane

artículo científico publicado en 2016

The structure and function of GGAs, the traffic controllers at the TGN sorting crossroads

artículo científico publicado en 2003

Three homologous ArfGAPs participate in coat protein I-mediated transport.

artículo científico publicado en 2009

cDNA cloning of bovine substance-K receptor through oocyte expression system.

artículo científico publicado en 1987

mRNA sequence for human cardiodilatin-atrial natriuretic factor precursor and regulation of precursor mRNA in rat atria

artículo científico publicado en 1984

Lista de obras de Kazuhisa Nakayama

A mutation of furin causes the lack of precursor-processing activity in human colon carcinoma LoVo cells

A second mutant allele of furin in the processing-incompetent cell line, LoVo. Evidence for involvement of the homo B domain in autocatalytic activation.

ADP-ribosylation factor-1 is sensitive to N-ethylmaleimide.

AMY-1 (associate of Myc-1) localization to the trans-Golgi network through interacting with BIG2, a guanine-nucleotide exchange factor for ADP-ribosylation factors

ARF1 and ARF3 are required for the integrity of recycling endosomes and the recycling pathway

ARF1 and ARF4 regulate recycling endosomal morphology and retrograde transport from endosomes to the Golgi apparatus ⬇️

ATP11C mutation is responsible for the defect in phosphatidylserine uptake in UPS-1 cells.

ATP9B, a P4-ATPase (a putative aminophospholipid translocase), localizes to the trans-Golgi network in a CDC50 protein-independent manner

ATP9B, a P4-ATPase (a putative aminophospholipid translocase), localizes to the trans-Golgi network in a CDC50 protein-independent manner.

Activation of histidine decarboxylase through post-translational cleavage by caspase-9 in a mouse mastocytoma P-815.

Adaptor gamma ear homology domain conserved in gamma-adaptin and GGA proteins that interact with gamma-synergin

Alteration of transbilayer phospholipid compositions is involved in cell adhesion, cell spreading, and focal adhesion formation.

Anterograde trafficking of ciliary MAP kinase-like ICK/CILK1 by the IFT machinery is required for intraciliary retrograde protein trafficking

Architecture of the IFT ciliary trafficking machinery and interplay between its components

Architectures of multisubunit complexes revealed by a visible immunoprecipitation assay using fluorescent fusion proteins

Arfaptins are localized to the trans-Golgi by interaction with Arl1, but not Arfs.

BBS1 is involved in retrograde trafficking of ciliary GPCRs in the context of the BBSome complex

BIG2, a guanine nucleotide exchange factor for ADP-ribosylation factors: its localization to recycling endosomes and implication in the endosome integrity

C11ORF74 interacts with the IFT-A complex and participates in ciliary BBSome localization

COPI-mediated retrieval of SCAP is crucial for regulating lipogenesis under basal and sterol-deficient conditions

Cellular and subcellular localization of EFA6C, a third member of the EFA6 family, in adult mouse Purkinje cells

Ciliary entry of KIF17 is dependent on its binding to the IFT-B complex via IFT46-IFT56 as well as on its nuclear localization signal.

Ciliary protein trafficking mediated by IFT and BBSome complexes with the aid of kinesin-2 and dynein-2 motors.

Ciliopathy-associated mutations of IFT122 impair ciliary protein trafficking but not ciliogenesis

Class I Arfs (Arf1 and Arf3) and Arf6 are localized to the Flemming body and play important roles in cytokinesis.

Cloning and Functional Expression of a Novel Endoprotease Involved in Prohormone Processing at Dibasic Sites1 ⬇️

Convergence of cell cycle regulation and growth factor signals on GRASP65

Differential effects of depletion of ARL1 and ARFRP1 on membrane trafficking between the trans-Golgi network and endosomes

Distinct roles of Rab11 and Arf6 in the regulation of Rab11-FIP3/arfophilin-1 localization in mitotic cells.

Dominant-negative mutant of BIG2, an ARF-guanine nucleotide exchange factor, specifically affects membrane trafficking from the trans-Golgi network through inhibiting membrane association of AP-1 and GGA coat proteins

Dual control of membrane targeting by PtdIns(4)P and ARF

Dynamin II is involved in endocytosis but not in the formation of transport vesicles from the trans-Golgi network

EFA6 activates Arf6 and participates in its targeting to the Flemming body during cytokinesis.

Effects of propeptide deletion on human renin secretion from mouse pituitary AtT-20 cells.

Establishment of the culture model system that reflects the process of terminal differentiation of connective tissue-type mast cells.

Expression of BIG2 and analysis of its function in mammalian cells

Expression of the mouse macrophage cystine transporter in Xenopus laevis oocytes

Functional cross-talk between Rab14 and Rab4 through a dual effector, RUFY1/Rabip4.

Functional involvement of TMF/ARA160 in Rab6-dependent retrograde membrane traffic.

Furin has the proalbumin substrate specificity and serpin inhibitory properties of an in situ hepatic convertase

Furin: a mammalian subtilisin/Kex2p-like endoprotease involved in processing of a wide variety of precursor proteins

GAT (GGA and Tom1) domain responsible for ubiquitin binding and ubiquitination.

GBF1-Arf-COPI-ArfGAP-mediated Golgi-to-ER transport involved in regulation of lipid homeostasis

GGA proteins associate with Golgi membranes through interaction between their GGAH domains and ADP-ribosylation factors

GM130 is a parallel tetramer with a flexible rod-like structure and N-terminally open (Y-shaped) and closed (I-shaped) conformations

Gamma-adaptin interacts directly with Rabaptin-5 through its ear domain.

Guanine nucleotide-exchange factors for arf GTPases: their diverse functions in membrane traffic.

Histamine synthesis is required for granule maturation in murine mast cells.

Identification and Characterization of Novel Clathrin Adaptor-related Proteins ⬇️

Identification and Subcellular Localization of a Novel Mammalian Dynamin-Related Protein Homologous to Yeast Vps1p and Dnm1p ⬇️

Identification and functional expression of a new member of the mammalian Kex2-like processing endoprotease family: its striking structural similarity to PACE4

Identification of a five-pass transmembrane protein family localizing in the Golgi apparatus and the ER.

Immunocytochemical localization of prohormone convertases PC1/PC3 and PC2 in rat pancreatic islets

Interaction of WDR60 intermediate chain with TCTEX1D2 light chain of the dynein-2 complex is crucial for ciliary protein trafficking

Interaction of heterotrimeric kinesin-II with IFT-B-connecting tetramer is crucial for ciliogenesis

Interactions of the dynein-2 intermediate chain WDR34 with the light chains are required for ciliary retrograde protein trafficking

Interleukin-1 and lipopolysaccharide enhance intercellular adhesion molecule-1 expression in cell lines of human squamous cell carcinoma

Intermolecular and interdomain interactions of a dynamin-related GTP-binding protein, Dnm1p/Vps1p-like protein

Intraflagellar transport-A complex mediates ciliary entry and retrograde trafficking of ciliary G protein-coupled receptors.

Involvement of CD44 in mast cell proliferation during terminal differentiation

Localization of Kex2-like processing endoproteases, furin and PC4, within mouse testis by in situ hybridization

Localization of furin to the trans-Golgi network and recycling from the cell surface involves Ser and Tyr residues within the cytoplasmic domain.

Mechanisms of membrane curvature generation in membrane traffic.

Membrane orientation of the precursor 74-kDa form of L-histidine decarboxylase.

Membrane recruitment of effector proteins by Arf and Rab GTPases.

Mitosis-Coupled, Microtubule-Dependent Clustering of Endosomal Vesicles around Centrosomes ⬇️

Modulation of primary cilia length by melanin-concentrating hormone receptor 1.

Molecular and enzymatic properties of furin, a Kex2-like endoprotease involved in precursor cleavage at Arg-X-Lys/Arg-Arg sites.

Molecular mechanism of membrane recruitment of GGA by ARF in lysosomal protein transport

Overall Architecture of the Intraflagellar Transport (IFT)-B Complex Containing Cluap1/IFT38 as an Essential Component of the IFT-B Peripheral Subcomplex

Overexpression of an ADP-ribosylation Factor-Guanine Nucleotide Exchange Factor, BIG2, Uncouples Brefeldin A-induced Adaptor Protein-1 Coat Dissociation and Membrane Tubulation ⬇️

Phospholipid Flippase ATP10A Translocates Phosphatidylcholine and Is Involved in Plasma Membrane Dynamics

Phospholipid flippase ATP11C is endocytosed and downregulated following Ca2+-mediated protein kinase C activation.

Phospholipid flippase activities and substrate specificities of human type IV P-type ATPases localized to the plasma membrane

Phospholipid-flipping activity of P4-ATPase drives membrane curvature

Positional and additive effects of basic amino acids on processing of precursor proteins within the constitutive secretory pathway

Practical method for targeted disruption of cilia-related genes by using CRISPR/Cas9-mediated, homology-independent knock-in system

Predominant expression of the short form of GGA3 in human cell lines and tissues.

Processing of wild-type and mutant proinsulin-like growth factor-IA by subtilisin-related proprotein convertases.