Lista de obras -

"Two is not enough" - Impact of the number of tissue samples obtained from stereotactic brain biopsies in suspected glioblastoma

artículo científico publicado en 2017

A subset of pediatric-type thalamic gliomas share a distinct DNA methylation profile, H3K27me3 loss and frequent alteration of EGFR

scientific article published on 01 November 2020

ATP synthase deficiency due to TMEM70 mutation leads to ultrastructural mitochondrial degeneration and is amenable to treatment

artículo científico publicado en 2015

AXL Inhibition in Macrophages Stimulates Host-versus-Leukemia Immunity and Eradicates Naïve and Treatment-Resistant Leukemia

publication published on 08 June 2021

Akt and mTORC1 signaling as predictive biomarkers for the EGFR antibody nimotuzumab in glioblastoma

artículo científico publicado en 2018

Analysis of cerebral angiogenesis in human glioblastomas.

artículo científico publicado en 2014

Angiopoietin-2 promotes myeloid cell infiltration in a β₂-integrin-dependent manner

artículo científico publicado en 2011

Antibody therapy to human L1CAM in a transgenic mouse model blocks local tumor growth but induces EMT.

artículo científico publicado en 2014

Assessment of molecular markers demonstrates concordance between samples acquired via stereotactic biopsy and open craniotomy in both anaplastic astrocytomas and glioblastomas

artículo científico publicado en 2017

Autophagy-associated proteins BAG3 and p62 in testicular cancer.

artículo científico publicado en 2015

BACE-1 is expressed in the blood-brain barrier endothelium and is upregulated in a murine model of Alzheimer's disease

artículo científico publicado en 2015

Benefit of tumor resection for recurrent glioblastoma.

artículo científico publicado en 2014

Bevacizumab and radiotherapy for the treatment of glioblastoma: brothers in arms or unholy alliance?

artículo científico publicado en 2016

Bevacizumab as a last-line treatment for glioblastoma following failure of radiotherapy, temozolomide and lomustine.

artículo científico publicado en 2017

Bevacizumab for Patients with Recurrent Multifocal Glioblastomas

artículo científico publicado en 2017

Bevacizumab treatment induces metabolic adaptation toward anaerobic metabolism in glioblastomas

artículo científico publicado en 2014

Brain invasion in otherwise benign meningiomas does not predict tumor recurrence

artículo científico publicado en 2016

Brain stem infarction associated with familial Mediterranean fever and central nervous system vasculitis

artículo científico publicado el 27 de mayo de 2013

C5b-9 deposits on endomysial capillaries in non-dermatomyositis cases

artículo científico publicado en 2016

CASP9 germline mutation in a family with multiple brain tumors

artículo científico publicado en 2016

CD133 expression is associated with small round blue cell tumour morphology in human central nervous system neoplasms

artículo científico publicado en 2011

CDKN2A/B homozygous deletion is associated with early recurrence in meningiomas

scientific article published on 08 July 2020

Cardiac period 2 in myocardial ischemia: clinical implications of a light dependent protein

artículo científico

Chordoid meningiomas can be sub-stratified into prognostically distinct DNA methylation classes and are enriched for heterozygous deletions of chromosomal arm 2p

artículo científico publicado en 2018

Confounding factors in diagnostics of MGMT promoter methylation status in glioblastomas in stereotactic biopsies.

artículo científico publicado en 2014

DNA methylation-based classification of central nervous system tumours

artículo científico publicado en 2018

Dabrafenib in patients with recurrent, BRAF V600E mutated malignant glioma and leptomeningeal disease.

artículo científico publicado en 2017

Diagnostic and clinical relevance of the autophago-lysosomal network in human gliomas

artículo científico publicado en 2016

Differential expression of the tumor suppressor A-kinase anchor protein 12 in human diffuse and pilocytic astrocytomas is regulated by promoter methylation

artículo científico publicado en 2013

Differential expression of vascular endothelial growth factor A, its receptors VEGFR-1, -2, and -3 and co-receptors neuropilin-1 and -2 does not predict bevacizumab response in human astrocytomas

artículo científico publicado en 2015

Differential utilization of ketone bodies by neurons and glioma cell lines: a rationale for ketogenic diet as experimental glioma therapy

artículo científico publicado en 2011

Disruption of peroxisome proliferator-activated receptor γ coactivator (PGC)-1α reverts key features of the neoplastic phenotype of glioma cells

scientific article published on 21 December 2018

Distribution and prognostic relevance of tumor-infiltrating lymphocytes (TILs) and PD-1/PD-L1 immune checkpoints in human brain metastases

artículo científico publicado en 2015

Downstream effects of plectin mutations in epidermolysis bullosa simplex with muscular dystrophy

artículo científico publicado en 2016

EGFL7 enhances surface expression of integrin αβ to promote angiogenesis in malignant brain tumors

artículo científico publicado en 2018

EGFL7 ligates αvβ3 integrin to enhance vessel formation

artículo científico publicado en 2013

EGFR heterogeneity and implications for therapeutic intervention in glioblastoma

artículo científico publicado en 2017

EGFRvIII mutations can emerge as late and heterogenous events in glioblastoma development and promote angiogenesis through Src activation.

artículo científico publicado en 2016

Elevated HLA-E levels in human glioblastomas but not in grade I to III astrocytomas correlate with infiltrating CD8+ cells.

artículo científico publicado en 2007

Endothelial cell-derived angiopoietin-2 is a therapeutic target in treatment-naive and bevacizumab-resistant glioblastoma

artículo científico publicado en 2015

ErbB2/HER2-Specific NK Cells for Targeted Therapy of Glioblastoma.

artículo científico publicado en 2015

Expression of vascular endothelial growth factor (VEGF) and its receptors VEGFR1 and VEGFR2 in primary and recurrent WHO grade III meningiomas

artículo científico publicado el 11 de marzo de 2013

FOXO3a orchestrates glioma cell responses to starvation conditions and promotes hypoxia-induced cell death

artículo científico publicado en 2016

Fermented Mistletoe Extract as a Multimodal Antitumoral Agent in Gliomas ⬇️

artículo científico publicado el 22 de octubre de 2012

Genetic and epigenetic characterization of posterior pituitary tumors

artículo científico publicado en 2021

Gliosarcoma with bone infiltration and extracranial growth: case report and review of literature ⬇️

artículo científico publicado el 19 de octubre de 2010

Head and neck cancer relapse after chemoradiotherapy correlates with CD163+ macrophages in primary tumour and CD11b+ myeloid cells in recurrences

artículo científico publicado en 2014

Hypoxia enhances the antiglioma cytotoxicity of B10, a glycosylated derivative of betulinic acid

artículo científico publicado en 2014

Identification of flubendazole as potential anti-neuroblastoma compound in a large cell line screen

artículo científico publicado en 2015

Immunohistochemical Assessment of Phosphorylated mTORC1-Pathway Proteins in Human Brain Tumors

artículo científico publicado en 2015

Infratentorial IDH-mutant astrocytoma is a distinct subtype

artículo científico publicado en 2020

Linking epigenetic signature and metabolic phenotype in IDH mutant and IDH wildtype diffuse glioma

artículo científico publicado en 2020

Loss of FUBP1 expression in gliomas predicts FUBP1 mutation and is associated with oligodendroglial differentiation, IDH1 mutation and 1p/19q loss of heterozygosity.

artículo científico publicado en 2014

Loss of histone H3K27me3 identifies a subset of meningiomas with increased risk of recurrence

artículo científico publicado en 2018

MR perfusion in and around the contrast-enhancement of primary CNS lymphomas.

artículo científico publicado en 2013

MYCN amplification drives an aggressive form of spinal ependymoma

scientific article published on 14 August 2019

Mammalian target of rapamycin complex 1 activation sensitizes human glioma cells to hypoxia-induced cell death

artículo científico publicado en 2017

MicroRNA-145 targets the metalloprotease ADAM17 and is suppressed in renal cell carcinoma patients

artículo científico publicado en 2013

Molecular crosstalk between tumour and brain parenchyma instructs histopathological features in glioblastoma

scientific article published on 25 March 2016

Multimodal imaging enables early detection and characterization of changes in tumor permeability of brain metastases

artículo científico publicado en 2013

Mutation-specific IDH1 antibody differentiates oligodendrogliomas and oligoastrocytomas from other brain tumors with oligodendroglioma-like morphology.

artículo científico publicado en 2010

Netrin-1 expression is an independent prognostic factor for poor patient survival in brain metastases

artículo científico publicado en 2014

Neurovascular EGFL7 regulates adult neurogenesis in the subventricular zone and thereby affects olfactory perception.

artículo científico publicado en 2017

Paired box gene 8 (PAX8) expression is associated with sonic hedgehog (SHH)/wingless int (WNT) subtypes, desmoplastic histology and patient survival in human medulloblastomas

artículo científico publicado en 2015

Perfusion MRI in the Evaluation of Suspected Glioblastoma Recurrence.

artículo científico publicado en 2015

Perioperative cerebral ischemia promote infiltrative recurrence in glioblastoma.

artículo científico publicado en 2015

Problems and challenges in the diagnosis of vertical infection with human cytomegalovirus (CMV): lessons from two accidental cases.

artículo científico publicado en 2011

Progression of pathology in PINK1-deficient mouse brain from splicing via ubiquitination, ER stress, and mitophagy changes to neuroinflammation

artículo científico publicado en 2017

Recurrent fusions in PLAGL1 define a distinct subset of pediatric-type supratentorial neuroepithelial tumors

artículo científico publicado en 2021

Spatio-temporal deleted in colorectal cancer (DCC) and netrin-1 expression in human foetal brain development.

artículo científico publicado en 2010

Suppression of antitumor T cell immunity by the oncometabolite (R)-2-hydroxyglutarate

scientific article published on 09 July 2018

Suppression of oxidative phosphorylation confers resistance against bevacizumab in experimental glioma

artículo científico publicado en 2017

Survivin inhibition and DNA double-strand break repair: a molecular mechanism to overcome radioresistance in glioblastoma.

artículo científico publicado en 2011

Sustained focal antitumor activity of bevacizumab in recurrent glioblastoma

artículo científico publicado en 2014

Symptomatic intraspinal oncocytic adrenocortical adenoma

artículo científico publicado en 2009

TERT promoter mutation and chromosome 6 loss define a high-risk subtype of ependymoma evolving from posterior fossa subependymoma

artículo científico publicado en 2021

Targetable ERBB2 mutations identified in neurofibroma/schwannoma hybrid nerve sheath tumors

scientific article published on 04 February 2020

The Impact of Early Corticosteroid Pretreatment Before Initiation of Chemotherapy in Patients With Primary Central Nervous System Lymphoma

scientific article published on 01 August 2019

The angiogenic switch leads to a metabolic shift in human glioblastoma

artículo científico publicado en 2016

The neurovascular unit as a selective barrier to polymorphonuclear granulocyte (PMN) infiltration into the brain after ischemic injury

artículo científico publicado en 2012

The physiological mTOR complex 1 inhibitor DDIT4 mediates therapy resistance in glioblastoma

artículo científico publicado en 2019

Tumor Vessel Normalization, Immunostimulatory Reprogramming, and Improved Survival in Glioblastoma with Combined Inhibition of PD-1, Angiopoietin-2, and VEGF

artículo científico publicado en 2019

β-Catenin-Gli1 interaction regulates proliferation and tumor growth in medulloblastoma.

artículo científico publicado en 2015

Lista de obras de

"Two is not enough" - Impact of the number of tissue samples obtained from stereotactic brain biopsies in suspected glioblastoma

A subset of pediatric-type thalamic gliomas share a distinct DNA methylation profile, H3K27me3 loss and frequent alteration of EGFR

ATP synthase deficiency due to TMEM70 mutation leads to ultrastructural mitochondrial degeneration and is amenable to treatment

AXL Inhibition in Macrophages Stimulates Host-versus-Leukemia Immunity and Eradicates Naïve and Treatment-Resistant Leukemia

Akt and mTORC1 signaling as predictive biomarkers for the EGFR antibody nimotuzumab in glioblastoma

Analysis of cerebral angiogenesis in human glioblastomas.

Angiopoietin-2 promotes myeloid cell infiltration in a β₂-integrin-dependent manner

Antibody therapy to human L1CAM in a transgenic mouse model blocks local tumor growth but induces EMT.

Assessment of molecular markers demonstrates concordance between samples acquired via stereotactic biopsy and open craniotomy in both anaplastic astrocytomas and glioblastomas

Autophagy-associated proteins BAG3 and p62 in testicular cancer.

BACE-1 is expressed in the blood-brain barrier endothelium and is upregulated in a murine model of Alzheimer's disease

Benefit of tumor resection for recurrent glioblastoma.

Bevacizumab and radiotherapy for the treatment of glioblastoma: brothers in arms or unholy alliance?

Bevacizumab as a last-line treatment for glioblastoma following failure of radiotherapy, temozolomide and lomustine.

Bevacizumab for Patients with Recurrent Multifocal Glioblastomas

Bevacizumab treatment induces metabolic adaptation toward anaerobic metabolism in glioblastomas

Brain invasion in otherwise benign meningiomas does not predict tumor recurrence

Brain stem infarction associated with familial Mediterranean fever and central nervous system vasculitis

C5b-9 deposits on endomysial capillaries in non-dermatomyositis cases

CASP9 germline mutation in a family with multiple brain tumors

CD133 expression is associated with small round blue cell tumour morphology in human central nervous system neoplasms

CDKN2A/B homozygous deletion is associated with early recurrence in meningiomas

Cardiac period 2 in myocardial ischemia: clinical implications of a light dependent protein

Chordoid meningiomas can be sub-stratified into prognostically distinct DNA methylation classes and are enriched for heterozygous deletions of chromosomal arm 2p

Confounding factors in diagnostics of MGMT promoter methylation status in glioblastomas in stereotactic biopsies.

DNA methylation-based classification of central nervous system tumours

Dabrafenib in patients with recurrent, BRAF V600E mutated malignant glioma and leptomeningeal disease.

Diagnostic and clinical relevance of the autophago-lysosomal network in human gliomas

Differential expression of the tumor suppressor A-kinase anchor protein 12 in human diffuse and pilocytic astrocytomas is regulated by promoter methylation

Differential expression of vascular endothelial growth factor A, its receptors VEGFR-1, -2, and -3 and co-receptors neuropilin-1 and -2 does not predict bevacizumab response in human astrocytomas

Differential utilization of ketone bodies by neurons and glioma cell lines: a rationale for ketogenic diet as experimental glioma therapy

Disruption of peroxisome proliferator-activated receptor γ coactivator (PGC)-1α reverts key features of the neoplastic phenotype of glioma cells

Distribution and prognostic relevance of tumor-infiltrating lymphocytes (TILs) and PD-1/PD-L1 immune checkpoints in human brain metastases

Downstream effects of plectin mutations in epidermolysis bullosa simplex with muscular dystrophy

EGFL7 enhances surface expression of integrin αβ to promote angiogenesis in malignant brain tumors

EGFL7 ligates αvβ3 integrin to enhance vessel formation

EGFR heterogeneity and implications for therapeutic intervention in glioblastoma

EGFRvIII mutations can emerge as late and heterogenous events in glioblastoma development and promote angiogenesis through Src activation.

Elevated HLA-E levels in human glioblastomas but not in grade I to III astrocytomas correlate with infiltrating CD8+ cells.

Endothelial cell-derived angiopoietin-2 is a therapeutic target in treatment-naive and bevacizumab-resistant glioblastoma

ErbB2/HER2-Specific NK Cells for Targeted Therapy of Glioblastoma.

Expression of vascular endothelial growth factor (VEGF) and its receptors VEGFR1 and VEGFR2 in primary and recurrent WHO grade III meningiomas

FOXO3a orchestrates glioma cell responses to starvation conditions and promotes hypoxia-induced cell death

Fermented Mistletoe Extract as a Multimodal Antitumoral Agent in Gliomas ⬇️

Genetic and epigenetic characterization of posterior pituitary tumors

Gliosarcoma with bone infiltration and extracranial growth: case report and review of literature ⬇️

Head and neck cancer relapse after chemoradiotherapy correlates with CD163+ macrophages in primary tumour and CD11b+ myeloid cells in recurrences

Hypoxia enhances the antiglioma cytotoxicity of B10, a glycosylated derivative of betulinic acid

Identification of flubendazole as potential anti-neuroblastoma compound in a large cell line screen

Immunohistochemical Assessment of Phosphorylated mTORC1-Pathway Proteins in Human Brain Tumors

Infratentorial IDH-mutant astrocytoma is a distinct subtype

Linking epigenetic signature and metabolic phenotype in IDH mutant and IDH wildtype diffuse glioma

Loss of FUBP1 expression in gliomas predicts FUBP1 mutation and is associated with oligodendroglial differentiation, IDH1 mutation and 1p/19q loss of heterozygosity.

Loss of histone H3K27me3 identifies a subset of meningiomas with increased risk of recurrence

MR perfusion in and around the contrast-enhancement of primary CNS lymphomas.

MYCN amplification drives an aggressive form of spinal ependymoma

Mammalian target of rapamycin complex 1 activation sensitizes human glioma cells to hypoxia-induced cell death

MicroRNA-145 targets the metalloprotease ADAM17 and is suppressed in renal cell carcinoma patients

Molecular crosstalk between tumour and brain parenchyma instructs histopathological features in glioblastoma

Multimodal imaging enables early detection and characterization of changes in tumor permeability of brain metastases

Mutation-specific IDH1 antibody differentiates oligodendrogliomas and oligoastrocytomas from other brain tumors with oligodendroglioma-like morphology.

Netrin-1 expression is an independent prognostic factor for poor patient survival in brain metastases

Neurovascular EGFL7 regulates adult neurogenesis in the subventricular zone and thereby affects olfactory perception.

Paired box gene 8 (PAX8) expression is associated with sonic hedgehog (SHH)/wingless int (WNT) subtypes, desmoplastic histology and patient survival in human medulloblastomas

Perfusion MRI in the Evaluation of Suspected Glioblastoma Recurrence.

Perioperative cerebral ischemia promote infiltrative recurrence in glioblastoma.

Problems and challenges in the diagnosis of vertical infection with human cytomegalovirus (CMV): lessons from two accidental cases.

Progression of pathology in PINK1-deficient mouse brain from splicing via ubiquitination, ER stress, and mitophagy changes to neuroinflammation

Recurrent fusions in PLAGL1 define a distinct subset of pediatric-type supratentorial neuroepithelial tumors

Spatio-temporal deleted in colorectal cancer (DCC) and netrin-1 expression in human foetal brain development.

Suppression of antitumor T cell immunity by the oncometabolite (R)-2-hydroxyglutarate

Suppression of oxidative phosphorylation confers resistance against bevacizumab in experimental glioma

Survivin inhibition and DNA double-strand break repair: a molecular mechanism to overcome radioresistance in glioblastoma.

Sustained focal antitumor activity of bevacizumab in recurrent glioblastoma

Symptomatic intraspinal oncocytic adrenocortical adenoma

TERT promoter mutation and chromosome 6 loss define a high-risk subtype of ependymoma evolving from posterior fossa subependymoma

Targetable ERBB2 mutations identified in neurofibroma/schwannoma hybrid nerve sheath tumors

The Impact of Early Corticosteroid Pretreatment Before Initiation of Chemotherapy in Patients With Primary Central Nervous System Lymphoma

The angiogenic switch leads to a metabolic shift in human glioblastoma