Lista de obras - Eyad Elkord - Dominio Público Uruguay

5T4 as a target for immunotherapy in renal cell carcinoma

artículo científico publicado en 2009

5T4 oncofetal antigen is expressed in high risk of relapse childhood pre-B acute lymphoblastic leukemia and is associated with a more invasive and chemotactic phenotype ⬇️

artículo científico publicado el 23 de enero de 2012

Adoptive transfer of T(reg) depleted autologous T cells in advanced renal cell carcinoma.

artículo científico publicado en 2007

Bead-isolated human CD4+CD25+ T regulatory cells are anergic and significantly suppress proliferation of CD4+CD25- T responder cells

artículo científico publicado en 2006

Blockade of PD-1, PD-L1, and TIM-3 Altered Distinct Immune- and Cancer-Related Signaling Pathways in the Transcriptome of Human Breast Cancer Explants

artículo científico publicado en 2020

CD4+ T-cell recognition of human 5T4 oncofoetal antigen: implications for initial depletion of CD25+ T cells

artículo científico publicado en 2007

CD8 T-cell recognition of human 5T4 oncofetal antigen.

artículo científico publicado en 2006

Circulating regulatory T cells in endometrial cancer: a role for age and menopausal status.

artículo científico publicado en 2010

Combining FoxP3 and Helios with GARP/LAP markers can identify expanded Treg subsets in cancer patients.

artículo científico publicado en 2016

Comment on “Expression of Helios in Peripherally Induced Foxp3+ Regulatory T Cells” ⬇️

artículo científico publicado el 15 de julio de 2012

Comparison of Myeloid Cells in Circulation and in the Tumor Microenvironment of Patients with Colorectal and Breast Cancers

artículo científico publicado en 2017

Correlation between CD8+ T cells specific for prostate-specific antigen and level of disease in patients with prostate cancer.

artículo científico publicado en 2006

DNA methylation and repressive H3K9 and H3K27 trimethylation in the promoter regions of PD-1, CTLA-4, TIM-3, LAG-3, TIGIT, and PD-L1 genes in human primary breast cancer.

artículo científico publicado en 2018

DNA methylation and repressive histones in the promoters of PD-1, CTLA-4, TIM-3, LAG-3, TIGIT, PD-L1, and galectin-9 genes in human colorectal cancer

article

DNA methylation in the promoters of PD-L1, MMP9, ARG1, galectin-9, TIM-3, VISTA and TGF-β genes in HLA-DR- myeloid cells, compared with HLA-DR+ antigen-presenting cells ⬇️

artículo científico publicado en 2020

DNA methylation of immune checkpoints in the peripheral blood of breast and colorectal cancer patients

scientific article published on 10 November 2018

Designing a broad-spectrum integrative approach for cancer prevention and treatment.

artículo científico publicado en 2015

Differential CTLs specific for prostate-specific antigen in healthy donors and patients with prostate cancer.

artículo científico publicado en 2005

Differential gene expression of tumor-infiltrating CD33+ myeloid cells in advanced- versus early-stage colorectal cancer

artículo científico publicado en 2020

Differential gene expression of tumor-infiltrating CD4+ T cells in advanced versus early stage colorectal cancer and identification of a gene signature of poor prognosis

artículo científico publicado en 2020

Differential gene expression of tumor-infiltrating CD8+ T cells in advanced versus early-stage colorectal cancer and identification of a gene signature of poor prognosis

scientific article published on 01 September 2020

Downregulation of immunosuppressive environment in patients with chronic HBV hepatitis on maintained remission

artículo científico publicado en 2015

Dual inhibition of STAT1 and STAT3 activation downregulates expression of PD-L1 in human breast cancer cells

artículo científico publicado en 2018

Editorial of Harnessing the Power of T Cells: The Promising Hope for a Universal Influenza Vaccine

scientific article published on 11 July 2020

Effect of pembrolizumab on CD4+ CD25+ , CD4+ LAP+ and CD4+ TIM-3+ T cell subsets

scientific article published on 17 February 2019

Epigenetic regulation of immune checkpoints and T cell exhaustion markers in tumor-infiltrating T cells of colorectal cancer patients

artículo científico publicado en 2020

Exosomes: Biological Carriers and Promising Tools for Cancer Immunotherapy

scientific article published on 16 July 2020

Expanded subpopulation of FoxP3+ T regulatory cells in renal cell carcinoma co-express Helios, indicating they could be derived from natural but not induced Tregs

artículo científico publicado en 2011

Expression of immune checkpoints and T cell exhaustion markers in early and advanced stages of colorectal cancer

scientific article published on 11 May 2020

Frequency of human T regulatory cells in peripheral blood is significantly reduced by cryopreservation

artículo científico publicado en 2009

Frequency of regulatory T cells in renal cell carcinoma patients and investigation of correlation with survival

scientific article published on 09 May 2007

Helios Should Not Be Cited as a Marker of Human Thymus-Derived Tregs. Commentary: Helios(+) and Helios(-) Cells Coexist within the Natural FOXP3(+) T Regulatory Cell Subset in Humans.

artículo científico publicado en 2016

Helios expression in FoxP3(+) T regulatory cells

artículo científico publicado en 2012

Helios, and not FoxP3, is the marker of activated Tregs expressing GARP/LAP.

artículo científico publicado en 2015

Human monocyte isolation methods influence cytokine production from in vitro generated dendritic cells

artículo científico publicado en 2005

Immune checkpoint inhibitors: recent progress and potential biomarkers

artículo científico publicado en 2018

Immune evasion in cancer: Mechanistic basis and therapeutic strategies.

artículo científico

Immune evasion mechanisms in colorectal cancer liver metastasis patients vaccinated with TroVax (MVA-5T4).

artículo científico publicado en 2009

Immunological response and overall survival in a subset of advanced renal cell carcinoma patients from a randomized phase 2/3 study of naptumomab estafenatox plus IFN-α versus IFN-α.

artículo científico publicado en 2015

Immunology and immunotherapy approaches for prostate cancer.

artículo científico publicado en 2007

Immunotherapy for gastrointestinal cancer: current status and strategies for improving efficacy

scientific article published on 01 April 2008

In vitro effect of IL-2 in combination with pazopanib or sunitinib on lymphocytes function and apoptosis of RCC cells

artículo científico publicado en 2014

In-vitro effect of pembrolizumab on different T regulatory cell subsets.

artículo científico publicado en 2017

Increased Levels of Circulating and Tumor-Infiltrating Granulocytic Myeloid Cells in Colorectal Cancer Patients

artículo científico publicado en 2016

Increased levels of granulocytic myeloid-derived suppressor cells in peripheral blood and tumour tissue of pancreatic cancer patients

artículo científico publicado en 2014

Modulation of lymphocyte regulation for cancer therapy: a phase II trial of tremelimumab in advanced gastric and esophageal adenocarcinoma.

artículo científico publicado en 2010

Myeloid Cells in Circulation and Tumor Microenvironment of Colorectal Cancer Patients with Early and Advanced Disease Stages

artículo científico publicado en 2020

Myeloid cells in circulation and tumor microenvironment of breast cancer patients

artículo científico publicado en 2017

Myeloid-derived suppressor cells in cancer: recent progress and prospects.

artículo científico publicado en 2013

Neuropilin 1: function and therapeutic potential in cancer

artículo científico publicado en 2013

Novel IFNγ ELISPOT assay for detection of functional carcinoembryonic antigen-specific chimeric antigen receptor-redirected T cells

artículo científico publicado en 2011

Novel expression of Neuropilin 1 on human tumor-infiltrating lymphocytes in colorectal cancer liver metastases

artículo científico publicado en 2014

Novel therapeutic strategies by regulatory T cells in allergy.

artículo científico publicado en 2008

PD-L1 Blockade by Atezolizumab Downregulates Signaling Pathways Associated with Tumor Growth, Metastasis, and Hypoxia in Human Triple Negative Breast Cancer

artículo científico publicado en 2019

PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications

artículo científico publicado en 2019

Pembrolizumab Interferes with the Differentiation of Human FOXP3+-Induced T Regulatory Cells, but Not with FOXP3 Stability, through Activation of mTOR

artículo científico publicado en 2019

Phenotypic alterations, clinical impact and therapeutic potential of regulatory T cells in cancer

artículo científico publicado en 2014

Regulatory T Cells in the Tumor Microenvironment and Cancer Progression: Role and Therapeutic Targeting

artículo científico publicado en 2016

Role of regulatory T cells in allergy: implications for therapeutic strategy.

artículo científico publicado en 2006

SARS-CoV-2 Infection and Lung Cancer: Potential Therapeutic Modalities

scientific article published on 05 August 2020

Salmonella-mediated tumor regression involves targeting of tumor myeloid suppressor cells causing a shift to M1-like phenotype and reduction in suppressive capacity

artículo científico publicado en 2014

Significance of CD44 and CD24 as Cancer Stem Cell Markers: An Enduring Ambiguity ⬇️

artículo científico publicado el 30 de mayo de 2012

Single-Cell Transcriptome Analysis Highlights a Role for Neutrophils and Inflammatory Macrophages in the Pathogenesis of Severe COVID-19

artículo científico publicado en 2020

Synergistic Effects of Nanomedicine Targeting TNFR2 and DNA Demethylation Inhibitor-An Opportunity for Cancer Treatment

artículo científico publicado en 2019

T cell responses and therapies against SARS-CoV-2 infection

scientific article published on 15 September 2020

T cell-based immunotherapy of metastatic renal cell carcinoma: modest success and future perspective.

artículo científico publicado en 2009

T regulatory cells in cancer: recent advances and therapeutic potential ⬇️

artículo científico publicado el 1 de noviembre de 2010

T-Regulatory Cells in Health and Disease

article

Targeting TIM-3 in solid tumors: innovations in the preclinical and translational realm and therapeutic potential

scientific article published on 24 October 2020

Therapeutic prospects of targeting myeloid-derived suppressor cells and immune checkpoints in cancer

artículo científico publicado en 2018

Thymus-Derived, Peripherally Derived, and in vitro-Induced T Regulatory Cells

artículo científico publicado en 2014

Transcriptomic Analyses Revealed Systemic Alterations in Gene Expression in Circulation and Tumor Microenvironment of Colorectal Cancer Patients

scientific article published on 11 December 2019

Transcriptomic Profiling of Circulating HLA-DR- Myeloid Cells, Compared with HLA-DR+ Myeloid Antigen-presenting Cells

artículo científico publicado en 2020

Transcriptomic profiling disclosed the role of DNA methylation and histone modifications in tumor-infiltrating myeloid-derived suppressor cell subsets in colorectal cancer

scientific article published on 15 January 2020

Treg-mediated acquired resistance to immune checkpoint inhibitors

scientific article published on 09 May 2019

Tremelimumab (anti-CTLA4) mediates immune responses mainly by direct activation of T effector cells rather than by affecting T regulatory cells

artículo científico publicado en 2010

Lista de obras de Eyad Elkord

5T4 as a target for immunotherapy in renal cell carcinoma

5T4 oncofetal antigen is expressed in high risk of relapse childhood pre-B acute lymphoblastic leukemia and is associated with a more invasive and chemotactic phenotype ⬇️

Adoptive transfer of T(reg) depleted autologous T cells in advanced renal cell carcinoma.

Bead-isolated human CD4+CD25+ T regulatory cells are anergic and significantly suppress proliferation of CD4+CD25- T responder cells

Blockade of PD-1, PD-L1, and TIM-3 Altered Distinct Immune- and Cancer-Related Signaling Pathways in the Transcriptome of Human Breast Cancer Explants

CD4+ T-cell recognition of human 5T4 oncofoetal antigen: implications for initial depletion of CD25+ T cells

CD8 T-cell recognition of human 5T4 oncofetal antigen.

Circulating regulatory T cells in endometrial cancer: a role for age and menopausal status.

Combining FoxP3 and Helios with GARP/LAP markers can identify expanded Treg subsets in cancer patients.

Comment on “Expression of Helios in Peripherally Induced Foxp3+ Regulatory T Cells” ⬇️

Comparison of Myeloid Cells in Circulation and in the Tumor Microenvironment of Patients with Colorectal and Breast Cancers

Correlation between CD8+ T cells specific for prostate-specific antigen and level of disease in patients with prostate cancer.

DNA methylation and repressive H3K9 and H3K27 trimethylation in the promoter regions of PD-1, CTLA-4, TIM-3, LAG-3, TIGIT, and PD-L1 genes in human primary breast cancer.

DNA methylation and repressive histones in the promoters of PD-1, CTLA-4, TIM-3, LAG-3, TIGIT, PD-L1, and galectin-9 genes in human colorectal cancer

DNA methylation in the promoters of PD-L1, MMP9, ARG1, galectin-9, TIM-3, VISTA and TGF-β genes in HLA-DR- myeloid cells, compared with HLA-DR+ antigen-presenting cells ⬇️

DNA methylation of immune checkpoints in the peripheral blood of breast and colorectal cancer patients

Designing a broad-spectrum integrative approach for cancer prevention and treatment.

Differential CTLs specific for prostate-specific antigen in healthy donors and patients with prostate cancer.

Differential gene expression of tumor-infiltrating CD33+ myeloid cells in advanced- versus early-stage colorectal cancer

Differential gene expression of tumor-infiltrating CD4+ T cells in advanced versus early stage colorectal cancer and identification of a gene signature of poor prognosis

Differential gene expression of tumor-infiltrating CD8+ T cells in advanced versus early-stage colorectal cancer and identification of a gene signature of poor prognosis

Downregulation of immunosuppressive environment in patients with chronic HBV hepatitis on maintained remission

Dual inhibition of STAT1 and STAT3 activation downregulates expression of PD-L1 in human breast cancer cells

Editorial of Harnessing the Power of T Cells: The Promising Hope for a Universal Influenza Vaccine

Effect of pembrolizumab on CD4+ CD25+ , CD4+ LAP+ and CD4+ TIM-3+ T cell subsets

Epigenetic regulation of immune checkpoints and T cell exhaustion markers in tumor-infiltrating T cells of colorectal cancer patients

Exosomes: Biological Carriers and Promising Tools for Cancer Immunotherapy

Expanded subpopulation of FoxP3+ T regulatory cells in renal cell carcinoma co-express Helios, indicating they could be derived from natural but not induced Tregs

Expression of immune checkpoints and T cell exhaustion markers in early and advanced stages of colorectal cancer

Frequency of human T regulatory cells in peripheral blood is significantly reduced by cryopreservation

Frequency of regulatory T cells in renal cell carcinoma patients and investigation of correlation with survival

Helios Should Not Be Cited as a Marker of Human Thymus-Derived Tregs. Commentary: Helios(+) and Helios(-) Cells Coexist within the Natural FOXP3(+) T Regulatory Cell Subset in Humans.

Helios expression in FoxP3(+) T regulatory cells

Helios, and not FoxP3, is the marker of activated Tregs expressing GARP/LAP.

Human monocyte isolation methods influence cytokine production from in vitro generated dendritic cells

Immune checkpoint inhibitors: recent progress and potential biomarkers

Immune evasion in cancer: Mechanistic basis and therapeutic strategies.

Immune evasion mechanisms in colorectal cancer liver metastasis patients vaccinated with TroVax (MVA-5T4).

Immunological response and overall survival in a subset of advanced renal cell carcinoma patients from a randomized phase 2/3 study of naptumomab estafenatox plus IFN-α versus IFN-α.

Immunology and immunotherapy approaches for prostate cancer.

Immunotherapy for gastrointestinal cancer: current status and strategies for improving efficacy

In vitro effect of IL-2 in combination with pazopanib or sunitinib on lymphocytes function and apoptosis of RCC cells

In-vitro effect of pembrolizumab on different T regulatory cell subsets.

Increased Levels of Circulating and Tumor-Infiltrating Granulocytic Myeloid Cells in Colorectal Cancer Patients

Increased levels of granulocytic myeloid-derived suppressor cells in peripheral blood and tumour tissue of pancreatic cancer patients

Modulation of lymphocyte regulation for cancer therapy: a phase II trial of tremelimumab in advanced gastric and esophageal adenocarcinoma.

Myeloid Cells in Circulation and Tumor Microenvironment of Colorectal Cancer Patients with Early and Advanced Disease Stages

Myeloid cells in circulation and tumor microenvironment of breast cancer patients

Myeloid-derived suppressor cells in cancer: recent progress and prospects.

Neuropilin 1: function and therapeutic potential in cancer

Novel IFNγ ELISPOT assay for detection of functional carcinoembryonic antigen-specific chimeric antigen receptor-redirected T cells

Novel expression of Neuropilin 1 on human tumor-infiltrating lymphocytes in colorectal cancer liver metastases

Novel therapeutic strategies by regulatory T cells in allergy.

PD-L1 Blockade by Atezolizumab Downregulates Signaling Pathways Associated with Tumor Growth, Metastasis, and Hypoxia in Human Triple Negative Breast Cancer

PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications

Pembrolizumab Interferes with the Differentiation of Human FOXP3+-Induced T Regulatory Cells, but Not with FOXP3 Stability, through Activation of mTOR

Phenotypic alterations, clinical impact and therapeutic potential of regulatory T cells in cancer

Regulatory T Cells in the Tumor Microenvironment and Cancer Progression: Role and Therapeutic Targeting

Role of regulatory T cells in allergy: implications for therapeutic strategy.

SARS-CoV-2 Infection and Lung Cancer: Potential Therapeutic Modalities

Salmonella-mediated tumor regression involves targeting of tumor myeloid suppressor cells causing a shift to M1-like phenotype and reduction in suppressive capacity

Significance of CD44 and CD24 as Cancer Stem Cell Markers: An Enduring Ambiguity ⬇️

Single-Cell Transcriptome Analysis Highlights a Role for Neutrophils and Inflammatory Macrophages in the Pathogenesis of Severe COVID-19

Synergistic Effects of Nanomedicine Targeting TNFR2 and DNA Demethylation Inhibitor-An Opportunity for Cancer Treatment

T cell responses and therapies against SARS-CoV-2 infection

T cell-based immunotherapy of metastatic renal cell carcinoma: modest success and future perspective.

T regulatory cells in cancer: recent advances and therapeutic potential ⬇️

T-Regulatory Cells in Health and Disease

Targeting TIM-3 in solid tumors: innovations in the preclinical and translational realm and therapeutic potential

Therapeutic prospects of targeting myeloid-derived suppressor cells and immune checkpoints in cancer

Thymus-Derived, Peripherally Derived, and in vitro-Induced T Regulatory Cells

Transcriptomic Analyses Revealed Systemic Alterations in Gene Expression in Circulation and Tumor Microenvironment of Colorectal Cancer Patients

Transcriptomic Profiling of Circulating HLA-DR- Myeloid Cells, Compared with HLA-DR+ Myeloid Antigen-presenting Cells

Transcriptomic profiling disclosed the role of DNA methylation and histone modifications in tumor-infiltrating myeloid-derived suppressor cell subsets in colorectal cancer

Treg-mediated acquired resistance to immune checkpoint inhibitors

Tremelimumab (anti-CTLA4) mediates immune responses mainly by direct activation of T effector cells rather than by affecting T regulatory cells