Lista de obras - Chiara Giacomelli - Dominio Público Uruguay

4-amino-6-alkyloxy-2-alkylthiopyrimidine derivatives as novel non-nucleoside agonists for the adenosine A1 receptor

artículo científico publicado en 2016

A new D₂ dopamine receptor agonist allosterically modulates A(2A) adenosine receptor signalling by interacting with the A(2A)/D₂ receptor heteromer

artículo científico publicado en 2011

Allosteric modulators of human A2B adenosine receptor

artículo científico publicado en 2013

Antioxidant Activity of Compounds Isolated from Elaeagnus umbellata Promotes Human Gingival Fibroblast Well-Being

artículo científico publicado en 2020

Apoptosis therapy in cancer: the first single-molecule co-activating p53 and the translocator protein in glioblastoma.

artículo científico publicado en 2014

Bax Activation Blocks Self-Renewal and Induces Apoptosis of Human Glioblastoma Stem Cells

artículo científico publicado en 2017

Bifunctional Inhibitors as a New Tool To Reduce Cancer Cell Invasion by Impairing MMP-9 Homodimerization.

artículo científico publicado en 2017

Brain ageing and neurodegenerative disease: The role of cellular waste management

artículo científico publicado en 2018

Carnosol controls the human glioblastoma stemness features through the epithelial-mesenchymal transition modulation and the induction of cancer stem cell apoptosis.

artículo científico publicado en 2017

Copper binding to naturally occurring, lactam form of angiogenin differs from that to recombinant protein, affecting their activity.

artículo científico publicado en 2015

Cytokine secretion responsiveness of lymphomonocytes following cortisol cell exposure: Sex differences

artículo científico publicado en 2018

Deepening the Topology of the Translocator Protein Binding Site by Novel N,N-Dialkyl-2-arylindol-3-ylglyoxylamides

artículo científico publicado en 2015

Discovery of N-hydroxyindole-based inhibitors of human lactate dehydrogenase isoform A (LDH-A) as starvation agents against cancer cells.

artículo científico publicado en 2011

Dual Inhibition of PDK1 and Aurora Kinase A: An Effective Strategy to Induce Differentiation and Apoptosis of Human Glioblastoma Multiforme Stem Cells.

artículo científico publicado en 2016

Dual MET and SMO Negative Modulators Overcome Resistance to EGFR Inhibitors in Human Nonsmall Cell Lung Cancer

artículo científico publicado en 2017

Epigenetic Modifications of the α-Synuclein Gene and Relative Protein Content Are Affected by Ageing and Physical Exercise in Blood from Healthy Subjects.

artículo científico publicado en 2018

Further studies on pyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-ones as potent and selective human A1 adenosine receptor antagonists

artículo científico publicado en 2014

Intracellular Bioinorganic Chemistry and Cross Talk Among Different -Omics

artículo científico publicado en 2016

Lactate dehydrogenase-A inhibition induces human glioblastoma multiforme stem cell differentiation and death

artículo científico publicado en 2015

Long lasting inhibition of Mdm2-p53 interaction potentiates mesenchymal stem cell differentiation into osteoblasts

artículo científico publicado en 2019

Microglial Pro-Inflammatory and Anti-Inflammatory Phenotypes Are Modulated by Translocator Protein Activation

artículo científico publicado en 2019

Modulation of A2B adenosine receptor by 1-Benzyl-3-ketoindole derivatives

artículo científico publicado en 2013

Molecular insight on the altered membrane trafficking of TrkA kinase dead mutants

scientific article published on 21 November 2019

Negative effects of a high tumour necrosis factor-α concentration on human gingival mesenchymal stem cell trophism: the use of natural compounds as modulatory agents.

artículo científico publicado en 2018

New insights into the anticancer activity of carnosol: p53 reactivation in the U87MG human glioblastoma cell line

artículo científico publicado en 2016

Novel fluorescent triazinobenzimidazole derivatives as probes for labelling human A1 and A2B adenosine receptor subtypes

artículo científico publicado en 2018

Novel positive allosteric modulators of A<sub>2B</sub> adenosine receptor acting as bone mineralisation promoters

artículo científico publicado en 2021

Osteoblast differentiation and survival: A role for A2B adenosine receptor allosteric modulators

artículo científico publicado en 2014

Osteogenesis Is Improved by Low Tumor Necrosis Factor Alpha Concentration through the Modulation of Gs-Coupled Receptor Signals

artículo científico publicado en 2017

Potential biomarkers and novel pharmacological targets in protein aggregation-related neurodegenerative diseases

artículo científico publicado en 2017

TSPO PIGA Ligands Promote Neurosteroidogenesis and Human Astrocyte Well-Being

artículo científico publicado en 2016

TSPO ligand residence time influences human glioblastoma multiforme cell death/life balance.

artículo científico publicado en 2015

TSPO ligand residence time: a new parameter to predict compound neurosteroidogenic efficacy

artículo científico publicado en 2016

Targeting the 18-kDa translocator protein: recent perspectives for neuroprotection

artículo científico publicado en 2015

The A2B Adenosine Receptor Modulates the Epithelial- Mesenchymal Transition through the Balance of cAMP/PKA and MAPK/ERK Pathway Activation in Human Epithelial Lung Cells

artículo científico publicado en 2018

The Ionophoric Activity of a Pro-Apoptotic VEGF165 Fragment on HUVEC Cells

scientific article published on 20 April 2020

Toward PET imaging of A2B adenosine receptors: a carbon-11 labeled triazinobenzimidazole tracer: Synthesis and imaging of a new A2B PET tracer.

artículo científico publicado en 2016

p53 functional inhibitors behaving like pifithrin-β counteract the Alzheimer peptide non-β-amyloid component effects in human SH-SY5Y cells

artículo científico publicado en 2014

α-Synuclein Aggregated with Tau and β-Amyloid in Human Platelets from Healthy Subjects: Correlation with Physical Exercise.

artículo científico publicado en 2018

α-Synuclein Heterocomplexes with β-Amyloid Are Increased in Red Blood Cells of Parkinson's Disease Patients and Correlate with Disease Severity.

artículo científico publicado en 2018

♦Copper (II) ions modulate Angiogenin activity in human endothelial cells.

artículo científico publicado en 2015

Lista de obras de Chiara Giacomelli

4-amino-6-alkyloxy-2-alkylthiopyrimidine derivatives as novel non-nucleoside agonists for the adenosine A1 receptor

A new D₂ dopamine receptor agonist allosterically modulates A(2A) adenosine receptor signalling by interacting with the A(2A)/D₂ receptor heteromer

Allosteric modulators of human A2B adenosine receptor

Antioxidant Activity of Compounds Isolated from Elaeagnus umbellata Promotes Human Gingival Fibroblast Well-Being

Apoptosis therapy in cancer: the first single-molecule co-activating p53 and the translocator protein in glioblastoma.

Bax Activation Blocks Self-Renewal and Induces Apoptosis of Human Glioblastoma Stem Cells

Bifunctional Inhibitors as a New Tool To Reduce Cancer Cell Invasion by Impairing MMP-9 Homodimerization.

Brain ageing and neurodegenerative disease: The role of cellular waste management

Carnosol controls the human glioblastoma stemness features through the epithelial-mesenchymal transition modulation and the induction of cancer stem cell apoptosis.

Copper binding to naturally occurring, lactam form of angiogenin differs from that to recombinant protein, affecting their activity.

Cytokine secretion responsiveness of lymphomonocytes following cortisol cell exposure: Sex differences

Deepening the Topology of the Translocator Protein Binding Site by Novel N,N-Dialkyl-2-arylindol-3-ylglyoxylamides

Discovery of N-hydroxyindole-based inhibitors of human lactate dehydrogenase isoform A (LDH-A) as starvation agents against cancer cells.

Dual Inhibition of PDK1 and Aurora Kinase A: An Effective Strategy to Induce Differentiation and Apoptosis of Human Glioblastoma Multiforme Stem Cells.

Dual MET and SMO Negative Modulators Overcome Resistance to EGFR Inhibitors in Human Nonsmall Cell Lung Cancer

Epigenetic Modifications of the α-Synuclein Gene and Relative Protein Content Are Affected by Ageing and Physical Exercise in Blood from Healthy Subjects.

Further studies on pyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-ones as potent and selective human A1 adenosine receptor antagonists

Intracellular Bioinorganic Chemistry and Cross Talk Among Different -Omics

Lactate dehydrogenase-A inhibition induces human glioblastoma multiforme stem cell differentiation and death

Long lasting inhibition of Mdm2-p53 interaction potentiates mesenchymal stem cell differentiation into osteoblasts

Microglial Pro-Inflammatory and Anti-Inflammatory Phenotypes Are Modulated by Translocator Protein Activation

Modulation of A2B adenosine receptor by 1-Benzyl-3-ketoindole derivatives

Molecular insight on the altered membrane trafficking of TrkA kinase dead mutants

Negative effects of a high tumour necrosis factor-α concentration on human gingival mesenchymal stem cell trophism: the use of natural compounds as modulatory agents.

New insights into the anticancer activity of carnosol: p53 reactivation in the U87MG human glioblastoma cell line

Novel fluorescent triazinobenzimidazole derivatives as probes for labelling human A1 and A2B adenosine receptor subtypes

Novel positive allosteric modulators of A<sub>2B</sub> adenosine receptor acting as bone mineralisation promoters

Osteoblast differentiation and survival: A role for A2B adenosine receptor allosteric modulators

Osteogenesis Is Improved by Low Tumor Necrosis Factor Alpha Concentration through the Modulation of Gs-Coupled Receptor Signals

Potential biomarkers and novel pharmacological targets in protein aggregation-related neurodegenerative diseases

TSPO PIGA Ligands Promote Neurosteroidogenesis and Human Astrocyte Well-Being

TSPO ligand residence time influences human glioblastoma multiforme cell death/life balance.

TSPO ligand residence time: a new parameter to predict compound neurosteroidogenic efficacy

Targeting the 18-kDa translocator protein: recent perspectives for neuroprotection

The A2B Adenosine Receptor Modulates the Epithelial- Mesenchymal Transition through the Balance of cAMP/PKA and MAPK/ERK Pathway Activation in Human Epithelial Lung Cells

The Ionophoric Activity of a Pro-Apoptotic VEGF165 Fragment on HUVEC Cells

Toward PET imaging of A2B adenosine receptors: a carbon-11 labeled triazinobenzimidazole tracer: Synthesis and imaging of a new A2B PET tracer.

p53 functional inhibitors behaving like pifithrin-β counteract the Alzheimer peptide non-β-amyloid component effects in human SH-SY5Y cells

α-Synuclein Aggregated with Tau and β-Amyloid in Human Platelets from Healthy Subjects: Correlation with Physical Exercise.

α-Synuclein Heterocomplexes with β-Amyloid Are Increased in Red Blood Cells of Parkinson's Disease Patients and Correlate with Disease Severity.

♦Copper (II) ions modulate Angiogenin activity in human endothelial cells.