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Lista de obras de Robert Clarke

A ground truth based comparative study on clustering of gene expression data.

artículo científico publicado en 2008

A maternal diet high in n − 6 polyunsaturated fats alters mammary gland development, puberty onset, and breast cancer risk among female rat offspring ⬇️

artículo científico publicado el 19 de agosto de 1997

A new class of small molecule estrogen receptor-alpha antagonists that overcome anti-estrogen resistance.

artículo científico publicado en 2015

AIB1 gene amplification and the instability of polyQ encoding sequence in breast cancer cell lines

artículo científico publicado en 2006

AISAIC: a software suite for accurate identification of significant aberrations in cancers

artículo científico publicado en 2013

Acquired estrogen independence and antiestrogen resistance in breast cancer: estrogen receptor driven phenotypes?

scientific article published on 01 October 1996

Acquisition of an antiestrogen-resistant phenotype in breast cancer: role of cellular and molecular mechanisms.

artículo científico publicado en 1996

Acquisition of estrogen independence induces TOB1-related mechanisms supporting breast cancer cell proliferation

artículo científico publicado en 2015

Acquisition of hormone-independent growth in MCF-7 cells is accompanied by increased expression of estrogen-regulated genes but without detectable DNA amplifications.

artículo científico publicado en 1993

Advancing Translational Research through Facility Design in Non-AMC Hospitals.

artículo científico

Adverse interactions between cytotoxic drugs and hormonal agents in human breast cancer cells.

artículo científico publicado en 1989

Alterations in behavior, steroid hormones and natural killer cell activity in male transgenic TGF alpha mice

artículo científico publicado el 14 de agosto de 1992

Analysis of tyrosine kinase mRNAs including four FGF receptor mRNAs expressed in MCF-7 breast-cancer cells

artículo científico publicado en 1992

Animal models of breast cancer: experimental design and their use in nutrition and psychosocial research.

artículo científico publicado en 1997

Antiestrogen Resistance and the Application of Systems Biology

artículo científico publicado en 2012

Antiestrogen resistance in breast cancer and the role of estrogen receptor signaling.

artículo científico publicado en 2003

Antiestrogens, aromatase inhibitors, and apoptosis in breast cancer

artículo científico publicado en 2005

Application of metabolomics in drug resistant breast cancer research

artículo científico publicado en 2015

Approaches to working in high-dimensional data spaces: gene expression microarrays

artículo científico publicado en 2008

Aromatase inhibitor plus ovarian suppression as adjuvant therapy in premenopausal women with breast cancer

artículo científico publicado en 2014

Association of interferon regulatory factor-1, nucleophosmin, nuclear factor-kappaB, and cyclic AMP response element binding with acquired resistance to Faslodex (ICI 182,780).

artículo científico publicado en 2002

Author Correction: BICORN: An R package for integrative inference of de novo cis-regulatory modules

artículo científico publicado en 2020

Autoantibodies to the nuclear phosphoprotein nucleophosmin in breast cancer patients

artículo científico publicado en 1998

Autophagy and endocrine resistance in breast cancer

artículo científico publicado en 2011

Autophagy and unfolded protein response (UPR) regulate mammary gland involution by restraining apoptosis-driven irreversible changes

article

Autophagy inhibitor 3-methyladenine potentiates apoptosis induced by dietary tocotrienols in breast cancer cells

artículo científico publicado en 2014

BACOM2.0 facilitates absolute normalization and quantification of somatic copy number alterations in heterogeneous tumor

artículo científico publicado en 2015

BADGE: a novel Bayesian model for accurate abundance quantification and differential analysis of RNA-Seq data.

artículo científico publicado en 2014

BCL2 and CASP8 regulation by NF-kappaB differentially affect mitochondrial function and cell fate in antiestrogen-sensitive and -resistant breast cancer cells.

artículo científico publicado en 2010

BICORN: An R package for integrative inference of de novo cis-regulatory modules

artículo científico publicado en 2020

BMRF-MI: integrative identification of protein interaction network by modeling the gene dependency

artículo científico publicado en 2015

BMRF-Net: a software tool for identification of protein interaction subnetworks by a bagging Markov random field-based method.

artículo científico publicado en 2015

BSSV: Bayesian based somatic structural variation identification with whole genome DNA-seq data

artículo científico publicado en 2014

Biologically inspired survival analysis based on integrating gene expression as mediator with genomic variants.

artículo científico publicado en 2016

Biomarker identification by knowledge-driven multilevel ICA and motif analysis.

artículo científico publicado en 2009

Breast cancer cell obatoclax response characterization using passivated-electrode insulator-based dielectrophoresis

artículo científico publicado en 2017

Breast cancer risk in rats fed a diet high in n-6 polyunsaturated fatty acids during pregnancy

artículo científico publicado en 1996

C-7 analogues of progesterone as potent inhibitors of the P-glycoprotein efflux pump.

artículo científico publicado en 2002

CRNET: An efficient sampling approach to infer functional regulatory networks by integrating large-scale ChIP-seq and time-course RNA-seq data.

artículo científico publicado en 2017

Cadmium mimics the in vivo effects of estrogen in the uterus and mammary gland.

artículo científico publicado en 2003

Cannibalism, cell survival, and endocrine resistance in breast cancer

artículo científico publicado en 2011

Caveolin-1 tyrosine phosphorylation enhances paclitaxel-mediated cytotoxicity.

artículo científico publicado en 2006

ChIP-BIT: Bayesian inference of target genes using a novel joint probabilistic model of ChIP-seq profiles.

artículo científico publicado en 2015

ChIP-GSM: Inferring active transcription factor modules to predict functional regulatory elements

artículo científico publicado en 2021

Changes in mammary caveolin-1 signaling pathways are associated with breast cancer risk in rats exposed to estradiol in utero or during prepuberty

artículo científico publicado en 2010

Co-inhibition of BCL-W and BCL2 restores antiestrogen sensitivity through BECN1 and promotes an autophagy-associated necrosis

artículo científico publicado en 2010

Common origins of MDA-MB-435 cells from various sources with those shown to have melanoma properties.

artículo científico publicado en 2004

Comparison of tamoxifen and letrozole response in mammary preneoplasia of ER and aromatase overexpressing mice defines an immune-associated gene signature linked to tamoxifen resistance.

artículo científico publicado en 2014

Competitive and allosteric interactions in ligand binding to P-glycoprotein as observed on an immobilized P-glycoprotein liquid chromatographic stationary phase.

artículo científico publicado en 2001

Conformational and receptor binding properties of human EGF and TGF-alpha second loop fragments

artículo científico publicado en 1988

Cross phenotype normalization of microarray data

artículo científico publicado en 2010

CyNetSVM: A Cytoscape App for Cancer Biomarker Identification Using Network Constrained Support Vector Machines.

artículo científico publicado en 2017

DBC-1 mediates endocrine resistant breast cancer cell survival.

artículo científico publicado en 2010

DDN: a caBIG® analytical tool for differential network analysis

artículo científico publicado en 2011

DM-BLD: differential methylation detection using a hierarchical Bayesian model exploiting local dependency.

artículo científico publicado en 2016

Data-driven detection of subtype-specific differentially expressed genes

artículo científico publicado en 2021

Development of an immobilized P-glycoprotein stationary phase for on-line liquid chromatographic determination of drug-binding affinities

artículo científico publicado en 2000

Differential distribution of protein phosphatase 2A in human breast carcinoma cell lines and its relation to estrogen receptor status.

artículo científico publicado en 1999

Do estrogens always increase breast cancer risk?

artículo científico publicado en 2002

Dynamic Modeling of the Interaction Between Autophagy and Apoptosis in Mammalian Cells.

artículo científico publicado en 2015

Dynamic modelling of oestrogen signalling and cell fate in breast cancer cells

artículo científico publicado en 2011

EGR1 regulates cellular metabolism and survival in endocrine resistant breast cancer.

artículo científico publicado en 2017

ERβ decreases breast cancer cell survival by regulating the IRE1/XBP-1 pathway.

artículo científico publicado en 2014

Early life affects the risk of developing breast cancer

artículo científico publicado en 1995

Effect of Berry Extracts and Bioactive Compounds on Fulvestrant (ICI 182,780) Sensitive and Resistant Cell Lines

artículo científico publicado en 2012

Effect of P-glycoprotein expression on sensitivity to hormones in MCF-7 human breast cancer cells

artículo científico publicado el 7 de octubre de 1992

Effect of cytotoxic drugs on estrogen receptor expression and response to tamoxifen in MCF-7 cells

artículo científico publicado en 1986

Effect of estrogen withdrawal on energy-rich phosphates and prediction of estrogen dependence monitored by in vivo 31P magnetic resonance spectroscopy of four human breast cancer xenografts.

artículo científico publicado en 1995

Effect of tamoxifen on the multidrug-resistant phenotype in human breast cancer cells: isobologram, drug accumulation, and M(r) 170,000 glycoprotein (gp170) binding studies.

artículo científico publicado en 1994

Effects of In Utero Exposure to Ethinyl Estradiol on Tamoxifen Resistance and Breast Cancer Recurrence in a Preclinical Model.

artículo científico publicado en 2016

Effects of Jaeumkanghwa-tang on tamoxifen responsiveness in preclinical ER+ breast cancer model

artículo científico publicado en 2019

Endocrine resistance in breast cancer--An overview and update

artículo científico publicado en 2015

Endocrine therapy resistance can be associated with high estrogen receptor alpha (ERalpha) expression and reduced ERalpha phosphorylation in breast cancer models.

artículo científico publicado en 2006

Endoplasmic reticulum stress, the unfolded protein response, and gene network modeling in antiestrogen resistant breast cancer

artículo científico publicado en 2011

Endoplasmic reticulum stress, the unfolded protein response, autophagy, and the integrated regulation of breast cancer cell fate.

artículo científico publicado en 2012

Enhancement of methotrexate cytotoxicity towards the MDA.MB.436 human breast cancer cell line by dipyridamole. The role of methotrexate polyglutamates

scientific article published on 01 September 1986

Enhancing reproducibility in cancer drug screening: how do we move forward?

artículo científico publicado en 2014

Estrogen receptor alpha positive breast tumors and breast cancer cell lines share similarities in their transcriptome data structures.

artículo científico publicado en 2006

Estrogen receptor-α signaling and localization regulates autophagy and unfolded protein response activation in ER+ breast cancer

artículo científico publicado en 2014

Estrogen-Induced Apoptosis in Breast Cancers Is Phenocopied by Blocking Dephosphorylation of Eukaryotic Initiation Factor 2 Alpha (eIF2α) Protein

scientific article published on 17 January 2019

Expression of an estrogen receptor variant lacking exon 3 in derivatives of MCF-7 cells with acquired estrogen independence or tamoxifen resistance.

artículo científico publicado en 2004

Expression patterns among interferon regulatory factor-1, human X-box binding protein-1, nuclear factor kappa B, nucleophosmin, estrogen receptor-alpha and progesterone receptor proteins in breast cancer tissue microarrays.

artículo científico publicado en 2006

Failure of 5-fluorouracil and methotrexate to destroy the reproductive integrity of a human breast cancer cell line (MCF-7) growing in vitro

scientific article published on 01 December 1981

Functionally active estrogen receptor isoform profiles in the breast tumors of African American women are different from the profiles in breast tumors of Caucasian women.

artículo científico publicado en 2002

G-DOC Plus - an integrative bioinformatics platform for precision medicine.

artículo científico publicado en 2016

G-DOC: a systems medicine platform for personalized oncology

artículo científico publicado en 2011

GIST: a Gibbs sampler to identify intracellular signal transduction pathways

artículo científico publicado en 2011

GX15-070 (obatoclax) induces apoptosis and inhibits cathepsin D- and L-mediated autophagosomal lysis in antiestrogen-resistant breast cancer cells

artículo científico publicado en 2013

Gamma-tocotrienol induced apoptosis is associated with unfolded protein response in human breast cancer cells

artículo científico publicado en 2011

Gene module identification from microarray data using nonnegative independent component analysis

artículo científico publicado en 2007

Gene network signaling in hormone responsiveness modifies apoptosis and autophagy in breast cancer cells

artículo científico publicado en 2009

Gene selection for multiclass prediction by weighted Fisher criterion

artículo científico publicado en 2007

Gene signaling pathways mediating the opposite effects of prepubertal low-fat and high-fat n-3 polyunsaturated fatty acid diets on mammary cancer risk.

artículo científico publicado en 2008

Genome-wide identification of significant aberrations in cancer genome.

artículo científico publicado en 2012

Glucose-regulated protein 78 controls cross-talk between apoptosis and autophagy to determine antiestrogen responsiveness

artículo científico publicado en 2012

Glutamine Metabolism Drives Growth in Advanced Hormone Receptor Positive Breast Cancer

artículo científico publicado en 2019

Glutamine metabolism and the unfolded protein response in MYC-driven breast cancer

artículo científico publicado en 2014

Growth and phenotypic characterization of porcine coronary artery smooth muscle cells

scientific article published on 01 March 1999

Guidelines for the use and interpretation of assays for monitoring autophagy

artículo científico publicado en 2012

Heat shock 70 kDa protein 5/glucose-regulated protein 78 “AMP”ing up autophagy ⬇️

artículo científico publicado el 1 de diciembre de 2012

Hormonal aspects of breast cancer. Growth factors, drugs and stromal interactions

artículo científico publicado el 1 de enero de 1992

Hormonal carcinogenesis in breast cancer: cellular and molecular studies of malignant progression.

artículo científico publicado en 1994

Hormone dependence of breast cancer cells and the effects of tamoxifen and estrogen: 31P NMR studies.

artículo científico publicado en 1995

Hormone resistance, invasiveness, and metastatic potential in breast cancer.

artículo científico publicado en 1993

Human X-box binding protein-1 confers both estrogen independence and antiestrogen resistance in breast cancer cell lines.

artículo científico publicado en 2007

Identification of condition-specific regulatory modules through multi-level motif and mRNA expression analysis.

artículo científico publicado en 2009

Identification of twenty alternatively spliced estrogen receptor alpha mRNAs in breast cancer cell lines and tumors using splice targeted primer approach

artículo científico publicado en 2000

Identifying cancer biomarkers by network-constrained support vector machines

artículo científico publicado en 2011

Identifying early events of gene expression in breast cancer with systems biology phylogenetics

artículo científico publicado en 2013

Identifying protein interaction subnetworks by a bagging Markov random field-based method.

artículo científico publicado en 2012

In vitro antineoplastic activity of C7-substituted mitomycin C analogues MC-77 and MC-62 against human breast-cancer cell lines

scientific article published on 01 January 1992

Inferring network interactions using recurrent neural networks and swarm intelligence

artículo científico publicado en 2006

Influence of berry polyphenols on receptor signaling and cell-death pathways: implications for breast cancer prevention

artículo científico publicado en 2012

Inhibition of BET proteins impairs estrogen-mediated growth and transcription in breast cancers by pausing RNA polymerase advancement.

artículo científico publicado en 2015

Inhibition of estrogen receptor function promotes porcine coronary artery smooth muscle cell proliferation

artículo científico publicado en 1999

Inhibition of growth of MCF-7 MIII human breast carcinoma in nude mice by treatment with agonists or antagonists of LH-RH

scientific article published on 01 January 1992

Integration of Network Biology and Imaging to Study Cancer Phenotypes and Responses

artículo científico publicado en 2014

Interaction of dietary polyphenols with molecular signaling pathways of antiestrogen resistance: possible role in breast cancer recurrence.

artículo científico publicado en 2012

Interferon regulatory factor-1 signaling regulates the switch between autophagy and apoptosis to determine breast cancer cell fate

artículo científico publicado en 2015

Introduction: Cancer Gene Networks

artículo científico publicado en 2017

Issues in experimental design and endpoint analysis in the study of experimental cytotoxic agents in vivo in breast cancer and other models.

artículo científico publicado en 1997

Iterative normalization of cDNA microarray data.

artículo científico publicado en 2002

KDDN: an open-source Cytoscape app for constructing differential dependency networks with significant rewiring

artículo científico publicado en 2014

Knowledge-fused differential dependency network models for detecting significant rewiring in biological networks ⬇️

artículo científico publicado en 2014

Knowledge-guided gene ranking by coordinative component analysis

artículo científico publicado en 2010

LCC15-MB cells are MDA-MB-435: a review of misidentified breast and prostate cell lines

artículo científico publicado en 2004

Latent variable and nICA modeling of pathway gene module composite.

artículo científico publicado en 2006

Lifetime Genistein Intake Increases the Response of Mammary Tumors to Tamoxifen in Rats

artículo científico publicado en 2017

Linking autophagy with inflammation through IRF1 signaling in ER+ breast cancer

artículo científico publicado en 2015

MCF7/LCC2: a 4-hydroxytamoxifen resistant human breast cancer variant that retains sensitivity to the steroidal antiestrogen ICI 182,780.

artículo científico publicado en 1993

MCF7/LCC9: an antiestrogen-resistant MCF-7 variant in which acquired resistance to the steroidal antiestrogen ICI 182,780 confers an early cross-resistance to the nonsteroidal antiestrogen tamoxifen ⬇️

artículo científico publicado el 15 de agosto de 1997

MDA435/LCC6 and MDA435/LCC6MDR1: ascites models of human breast cancer.

artículo científico publicado en 1996

MYC regulates the unfolded protein response and glucose and glutamine uptake in endocrine resistant breast cancer

artículo científico publicado en 2014

Maternal exposure to genistein during pregnancy increases carcinogen-induced mammary tumorigenesis in female rat offspring.

artículo científico publicado en 1999

Maternal exposure to tamoxifen during pregnancy increases carcinogen-induced mammary tumorigenesis among female rat offspring

scientific article published on 01 January 2000

Maternal genistein exposure mimics the effects of estrogen on mammary gland development in female mouse offspring.

artículo científico publicado en 1998

Mathematical modelling of transcriptional heterogeneity identifies novel markers and subpopulations in complex tissues

artículo científico publicado en 2016

Mathematical models of the transitions between endocrine therapy responsive and resistant states in breast cancer.

artículo científico publicado en 2014

Mechanisms mediating the effects of prepubertal (n-3) polyunsaturated fatty acid diet on breast cancer risk in rats.

artículo científico publicado en 2005

Meta-analysis of soy intake and breast cancer risk.

artículo científico publicado en 2006

Modeling the estrogen receptor to growth factor receptor signaling switch in human breast cancer cells

artículo científico publicado en 2013

Molecular mechanisms of tamoxifen-associated endometrial cancer (Review).

artículo científico publicado en 2015

Monoclonal antibody against the ectodomain of E-cadherin (DECMA-1) suppresses breast carcinogenesis: involvement of the HER/PI3K/Akt/mTOR and IAP pathways

artículo científico publicado en 2013

Motif-directed network component analysis for regulatory network inference

artículo científico publicado en 2008

Multidrug resistance in breast cancer: a meta-analysis of MDR1/gp170 expression and its possible functional significance.

artículo científico publicado en 1997

Multidrug resistance/P-glycoprotein and breast cancer: review and meta-analysis

artículo científico publicado en 2005

Multilevel support vector regression analysis to identify condition-specific regulatory networks

artículo científico publicado en 2010

NF-κB signaling is required for XBP1 (unspliced and spliced)-mediated effects on antiestrogen responsiveness and cell fate decisions in breast cancer

artículo científico publicado en 2014

NTP-CERHR expert panel report on the developmental toxicity of soy infant formula.

artículo científico

Oestrogen receptor status and the response of human breast cancer cell lines to a combination of methotrexate and 17-beta oestradiol.

artículo científico publicado en 1985

Opposing behavioural alterations in male and female transgenic TGF alpha mice: association with tumour susceptibility

artículo científico publicado en 1993

Optimized multilayer perceptrons for molecular classification and diagnosis using genomic data.

artículo científico publicado en 2006

Orphan nuclear receptors in breast cancer pathogenesis and therapeutic response.

artículo científico publicado en 2010

Overcoming cancer resistance.

artículo científico publicado en 2015

Overexpression of the dominant-negative form of interferon regulatory factor 1 in oligodendrocytes protects against experimental autoimmune encephalomyelitis

artículo científico publicado en 2011

PSSV: a novel pattern-based probabilistic approach for somatic structural variation identification.

artículo científico publicado en 2016

Perinatal factors increase breast cancer risk.

artículo científico publicado en 1994

Physical and functional interactions between Cas and c-Src induce tamoxifen resistance of breast cancer cells through pathways involving epidermal growth factor receptor and signal transducer and activator of transcription 5b.

artículo científico publicado en 2006

Poly-ADP-Ribosylation of Estrogen Receptor-Alpha by PARP1 Mediates Antiestrogen Resistance in Human Breast Cancer Cells

artículo científico publicado en 2019

Profile of Robert Clarke. Interviewed by Kristie Nybo, Ph.D.

artículo científico publicado en 2011

Progression of human breast cancer cells from hormone-dependent to hormone-independent growth both in vitro and in vivo.

artículo científico publicado en 1989

Progressive loss of estrogen receptor alpha cofactor recruitment in endocrine resistance.

artículo científico publicado en 2007

Psychosocial factors in the development and progression of breast cancer.

artículo científico publicado en 1994

RNA Interference Screening to Identify Proliferation Determinants in Breast Cancer Cells.

artículo científico publicado en 2017

RNA interference screening methods to identify proliferation determinants and mechanisms of resistance to immune attack

artículo científico publicado en 2019

Radiogenomic signatures reveal multiscale intratumour heterogeneity associated with biological functions and survival in breast cancer

scientific article published on 25 September 2020

Reconstruction of gene regulatory modules in cancer cell cycle by multi-source data integration

artículo científico publicado en 2010

Reconstruction of transcriptional regulatory networks by stability-based network component analysis.

artículo científico publicado en 2013

Reduction of the anti-metabolic and anti-proliferative effects of methotrexate by 17 beta-oestradiol in a human breast carcinoma cell line, MDA-MB-436

scientific article published on 01 January 1983

Reduction of the membrane fluidity of human breast cancer cells by tamoxifen and 17 beta-estradiol

artículo científico publicado en 1990

Regulatory component analysis: A semi-blind extraction approach to infer gene regulatory networks with imperfect biological knowledge ⬇️

artículo científico publicado el 8 de diciembre de 2011

Resistance to TNF-alpha and adriamycin in the human breast cancer MCF-7 cell line: relationship to MDR1, MnSOD, and TNF gene expression.

artículo científico publicado en 1994

Reversal of tamoxifen resistance of human breast carcinomas in vivo by neutralizing antibodies to transforming growth factor-beta.

artículo científico publicado en 1999

Reverse engineering module networks by PSO-RNN hybrid modeling

artículo científico publicado en 2009

Robust identification of transcriptional regulatory networks using a Gibbs sampler on outlier sum statistic

artículo científico publicado en 2014

Role of GRP78 in promoting therapeutic-resistant breast cancer

artículo científico publicado en 2015

Small-molecule "BRCA1-mimetics" are antagonists of estrogen receptor-α

artículo científico publicado en 2014

Social isolation induces autophagy in the mouse mammary gland: link to increased mammary cancer risk.

artículo científico publicado en 2016

SparseIso: A novel Bayesian approach to identify alternatively spliced isoforms from RNA-seq data

artículo científico publicado en 2017

Steroid metabolism in the hormone dependent MCF-7 human breast carcinoma cell line and its two hormone resistant subpopulations MCF-7/LCC1 and MCF-7/LCC2.

artículo científico publicado en 1997

Systems biology: perspectives on multiscale modeling in research on endocrine-related cancers

scientific article published on 01 June 2019

TMEM33: a new stress-inducible endoplasmic reticulum transmembrane protein and modulator of the unfolded protein response signaling

scientific journal article

The A4396G polymorphism in interferon regulatory factor 1 is frequently expressed in breast cancer cell lines.

artículo científico publicado en 2007

The Role of Interferon Regulatory Factor-1 (IRF1) in Overcoming Antiestrogen Resistance in the Treatment of Breast Cancer.

artículo científico publicado en 2011

The effect of leucovorin on the synthesis of methotrexate poly-gamma-glutamates in the MCF-7 human breast cancer cell line

artículo científico publicado en 1985

The effect of the rate of cell proliferation on the synthesis of methotrexate poly-gamma-glutamates in two human breast cancer cell lines.

artículo científico publicado en 1985

The effects of Mg2+ ions or EDTA on nuclear integrity and apparent subcellular distribution of unoccupied oestrogen receptors in breast cancer cells.

artículo científico publicado en 1986

The effects of a constitutive expression of transforming growth factor-alpha on the growth of MCF-7 human breast cancer cells in vitro and in vivo.

artículo científico publicado en 1989

The enantioselective binding of mefloquine enantiomers to P-glycoprotein determined using an immobilized P-glycoprotein liquid chromatographic stationary phase.

artículo científico publicado en 2001

The invasive and metastatic properties of hormone-independent but hormone-responsive variants of MCF-7 human breast cancer cells.

artículo científico publicado en 1993

The kinetics of methotrexate polyglutamate formation and efflux in a human breast cancer cell line (MDA.MB.436): the effect of insulin

scientific article published on 01 January 1983

The multidrug resistance phenotype: 31P nuclear magnetic resonance characterization and 2-deoxyglucose toxicity.

artículo científico publicado en 1991

The nuclear factor kappa B inhibitor parthenolide restores ICI 182,780 (Faslodex; fulvestrant)-induced apoptosis in antiestrogen-resistant breast cancer cells

artículo científico publicado en 2005

The p160 family coactivators regulate breast cancer cell proliferation and invasion through autocrine/paracrine activity of SDF-1alpha/CXCL12.

artículo científico publicado en 2005

The proapoptotic molecule BLID interacts with Bcl-XL and its downregulation in breast cancer correlates with poor disease-free and overall survival.

artículo científico publicado en 2010

The properties of high-dimensional data spaces: implications for exploring gene and protein expression data.

artículo científico publicado en 2008

The role of X-box binding protein-1 in tumorigenicity.

artículo científico publicado en 2009

The role of preclinical animal models in breast cancer drug development

artículo científico publicado en 2009

The unoccupied estrogen receptor: some comments on localization

artículo científico publicado en 1986

Therapeutically activating RB: reestablishing cell cycle control in endocrine therapy-resistant breast cancer

artículo científico publicado en 2011

Timing of dietary fat exposure and mammary tumorigenesis: role of estrogen receptor and protein kinase C activity

artículo científico publicado en 1998

Two-dimensional gel electrophoresis analyses identify nucleophosmin as an estrogen regulated protein associated with acquired estrogen-independence in human breast cancer cells

scientific article published on 01 December 1998

Tyrosine-phosphorylated caveolin-1 (Tyr-14) increases sensitivity to paclitaxel by inhibiting BCL2 and BCLxL proteins via c-Jun N-terminal kinase (JNK).

artículo científico publicado en 2012

UNDO: a Bioconductor R package for unsupervised deconvolution of mixed gene expressions in tumor samples.

artículo científico publicado en 2014

Unfolding the Role of Stress Response Signaling in Endocrine Resistant Breast Cancers.

artículo científico publicado en 2015

Unsupervised deconvolution of dynamic imaging reveals intratumor vascular heterogeneity and repopulation dynamics

artículo científico publicado en 2014

Use of ERE and reporter gene constructs to assess putative estrogenic activity.

artículo científico publicado en 1999

VAV3 mediates resistance to breast cancer endocrine therapy.

artículo científico publicado en 2014

Vitamin E succinate inhibits survivin and induces apoptosis in pancreatic cancer cells ⬇️

artículo científico publicado el 13 de agosto de 2011

When is a vesicle not just a vesicle: mitochondrial spheroids and mitochondrial autophagosomes

artículo científico publicado en 2014

caBIG VISDA: modeling, visualization, and discovery for cluster analysis of genomic data

artículo científico publicado en 2008

interferon regulatory factor-1 mediates the proapoptotic but not cell cycle arrest effects of the steroidal antiestrogen ICI 182,780 (faslodex, fulvestrant).

artículo científico publicado en 2004

mAPC-GibbsOS: an integrated approach for robust identification of gene regulatory networks.

artículo científico publicado en 2013

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