Lista de obras - Sophie Lotersztajn - Dominio Público Uruguay

15-deoxy-Delta 12,14-prostaglandin J2 induces apoptosis of human hepatic myofibroblasts. A pathway involving oxidative stress independently of peroxisome-proliferator-activated receptors.

artículo científico publicado en 2001

A defect in endothelial autophagy occurs in patients with non-alcoholic steatohepatitis and promotes inflammation and fibrosis

scientific article published on 11 November 2019

A glucagon fragment is responsible for the inhibition of the liver Ca2+ pump by glucagon

artículo científico publicado en 1987

A high affinity calcium-stimulated magnesium-dependent ATPase in rat liver plasma membranes. Dependence of an endogenous protein activator distinct from calmodulin

scientific article published on 01 November 1981

A membrane-bound protein inhibitor of the high affinity Ca ATPase in rat liver plasma membranes

scientific article published on 01 June 1982

AJP-Cell Physiology begins a theme series on the control of the proteostasis network in health and diseases.

artículo científico publicado en 2016

AJP-Cell begins a theme series on tissue fibrosis

artículo científico publicado en 2012

AJP-cell begins a theme series on cellular mechanisms of endoplasmic reticulum stress signaling in health and disease

artículo científico publicado en 2014

ASMase regulates autophagy and lysosomal membrane permeabilization and its inhibition prevents early stage non-alcoholic steatohepatitis

artículo científico publicado en 2014

Activation of Na+/Ca2+ exchange by adenosine in ewe heart sarcolemma is mediated by a pertussis toxin-sensitive G protein

artículo científico publicado en 1990

Adipose tissue macrophages: MR tracking to monitor obesity-associated inflammation

artículo científico publicado en 2012

American Journal of Physiology-Cell Physiology initiates a series of articles around a theme: autophagy is the first theme

scientific article published on 13 January 2010

Antifibrogenic role of the cannabinoid receptor CB2 in the liver

artículo científico publicado en 2005

Antiproliferative effects of ET-1 in human liver Ito cells: an ETB- and a cyclic AMP-mediated pathway

artículo científico publicado en 1995

Aryl hydrocarbon receptor-dependent induction of liver fibrosis by dioxin

artículo científico publicado en 2013

Autophagy in chronic liver diseases: the two faces of Janus

artículo científico publicado en 2016

Autophagy in liver diseases: Time for translation?

artículo científico publicado en 2019

Autophagy: a multifaceted partner in liver fibrosis

artículo científico

Beneficial paracrine effects of cannabinoid receptor 2 on liver injury and regeneration

artículo científico publicado en 2010

Biological effects of C-type natriuretic peptide in human myofibroblastic hepatic stellate cells

artículo científico publicado en 1999

Biological effects of sarafotoxin in rat liver

scientific article published on 01 March 1992

CB1 cannabinoid receptor antagonism: a new strategy for the treatment of liver fibrosis

scientific article published on 21 May 2006

Cannabinoid CB2 receptor potentiates obesity-associated inflammation, insulin resistance and hepatic steatosis

artículo científico publicado en 2009

Cannabinoid CB2 receptors protect against alcoholic liver disease by regulating Kupffer cell polarization in mice

scientific article published on 06 September 2011

Cannabinoid receptor 2 counteracts interleukin-17-induced immune and fibrogenic responses in mouse liver

artículo científico publicado en 2013

Cannabinoid receptors as new targets of antifibrosing strategies during chronic liver diseases

artículo científico publicado en 2007

Cannabinoid receptors as novel therapeutic targets for the management of non-alcoholic steatohepatitis.

artículo científico publicado en 2008

Cannabinoid receptors as therapeutic targets in the management of liver diseases

artículo científico publicado en 2008

Cannabinoid signaling and liver therapeutics

artículo científico publicado en 2013

Cellular targeting of the apoptosis-inducing compound gliotoxin to fibrotic rat livers.

artículo científico publicado en 2007

Chronic Exposure to Low Doses of Dioxin Promotes Liver Fibrosis Development in the C57BL/6J Diet-Induced Obesity Mouse Model

scientific article published on 07 October 2016

Chronic hypocalcemia of vitamin D deficiency leads to lower intracellular calcium concentrations in rat hepatocytes

artículo científico publicado en 1994

Cigarette smoke exposure: a novel cofactor of NAFLD progression?

artículo científico publicado en 2009

Combination of CCl4 with alcoholic and metabolic injuries mimics human liver fibrosis

artículo científico publicado en 2019

Coupling of endothelin B receptors to the calcium pump and phospholipase C via Gs and Gq in rat liver

artículo científico publicado en 1994

Daily cannabis smoking as a risk factor for progression of fibrosis in chronic hepatitis C.

artículo científico publicado en 2005

Daily cannabis use: a novel risk factor of steatosis severity in patients with chronic hepatitis C.

artículo científico publicado en 2007

Elevated expression of osteopontin may be related to adipose tissue macrophage accumulation and liver steatosis in morbid obesity

artículo científico publicado en 2008

Endocannabinoids and their role in fatty liver disease.

artículo científico publicado en 2010

Endocannabinoids as novel mediators of liver diseases.

artículo científico publicado en 2006

Endothelin inhibits the calcium pump and stimulates phosphoinositide phospholipase C in liver plasma membranes via two different G proteins, Gs and Gq

artículo científico publicado en 1993

Endothelin-1 induces liver vasoconstriction through both ETA and ETB receptors

scientific article published on 01 May 1997

Endothelin-1 stimulates sphingosine kinase in human hepatic stellate cells. A novel role for sphingosine-1-P as a mediator of growth inhibition

scientific article published on 01 April 2000

Environmental factors as disease accelerators during chronic hepatitis C.

artículo científico publicado en 2008

From the Editor's Desk…: December 2019

scientific article published on 01 December 2019

From the Editor's Desk…: November 2019

artículo científico publicado en 2019

From the Editor's desk....: November 2018

From the Editor's desk....: September 2018

artículo científico publicado en 2018

Glucagon-(19-29) exerts a biphasic action on the liver plasma membrane Ca2+ pump which is mediated by G proteins.

artículo científico publicado en 1990

Glucagon-(19-29), a Ca2+ pump inhibitory peptide, is processed from glucagon in the rat liver plasma membrane by a thiol endopeptidase

scientific article published on 01 December 1990

Gs mediates hormonal inhibition of the calcium pump in liver plasma membranes

scientific article published on 01 February 1993

Heme oxygenase-1 is an antifibrogenic protein in human hepatic myofibroblasts

artículo científico publicado en 2003

Hepatic cytoprotection (5). Calcium and hepatotoxicity

scientific article published on 01 August 1989

Hepatic fibrosis: molecular mechanisms and drug targets

artículo científico publicado en 2005

Homocysteine decreases endothelin-1 production by cultured human endothelial cells.

artículo científico publicado en 1999

Human hepatic stellate cells are not permissive for hepatitis C virus entry and replication

artículo científico publicado en 2014

Human liver plasma membrane Ca-ATPase: Identification and sensitivity to calcium antagonists ⬇️

artículo científico publicado el 1 de noviembre de 1982

Hyperactivation of anandamide synthesis and regulation of cell-cycle progression via cannabinoid type 1 (CB1) receptors in the regenerating liver

artículo científico publicado en 2011

IRAP-dependent endosomal T cell receptor signalling is essential for T cell responses

artículo científico publicado en 2020

Inhibition by glucagon of the calcium pump in liver plasma membranes.

artículo científico publicado en 1984

Inhibition of monoacylglycerol lipase, an anti-inflammatory and antifibrogenic strategy in the liver

Inhibition of the calcium pump by human parathyroid hormone-(1-34) and human calcitonin in liver plasma membranes

artículo científico publicado en 1990

Journal of Hepatology: The Home of Liver Research, 2015-2019

artículo científico publicado en 2019

LC3-associated phagocytosis in myeloid cells, a fireman that restrains inflammation and liver fibrosis, via immunoreceptor inhibitory signalling

artículo científico publicado en 2020

LC3-associated phagocytosis protects against inflammation and liver fibrosis via immunoreceptor inhibitory signaling

scientific article published on 01 April 2020

Lack of monoacylglycerol lipase prevents hepatic steatosis by favoring lipid storage in adipose tissue and intestinal malabsorption

scientific article published on 02 May 2019

Long term in vivo biotransformation of iron oxide nanoparticles

M2 Kupffer cells promote M1 Kupffer cell apoptosis: a protective mechanism against alcoholic and nonalcoholic fatty liver disease

artículo científico publicado en 2013

M2 kupffer cells promote hepatocyte senescence: an IL-6-dependent protective mechanism against alcoholic liver disease

artículo científico publicado en 2014

MAIT cell inhibition promotes liver fibrosis regression by reprogramming macrophage phenotype

artículo científico publicado en 2022

Macrophage autophagy protects against liver fibrosis in mice

artículo científico publicado en 2015

Molecular mechanisms regulating the antifibrogenic protein heme-oxygenase-1 in human hepatic myofibroblasts

artículo científico publicado en 2004

Monoacylglycerol Lipase Inhibition Protects From Liver Injury in Mouse Models of Sclerosing Cholangitis

artículo científico publicado en 2019

Mucosal-associated invariant T cells and disease

scientific article published on 01 October 2019

Mucosal-associated invariant T cells are a profibrogenic immune cell population in the liver.

artículo científico publicado en 2018

New pieces in the complex puzzle of aberrant vacuolation. Focus on "Active vacuolar H+ ATPase and functional cycle of Rab5 are required for the vacuolation defect triggered by PtdIns(3,5)P2 loss under PIKfyve or Vps34 deficiency".

artículo científico publicado en 2016

Novel role for carbohydrate responsive element binding protein in the control of ethanol metabolism and susceptibility to binge drinking

artículo científico publicado en 2015

Oral methylthioadenosine administration attenuates fibrosis and chronic liver disease progression in Mdr2-/- mice

artículo científico publicado en 2010

Pathophysiology of NASH: perspectives for a targeted treatment

scientific article published on January 2013

Platelet-derived Growth Factor-BB and Thrombin Generate Positive and Negative Signals for Human Hepatic Stellate Cell Proliferation

scientific article published in Journal of Biological Chemistry

Pre-therapy liver transcriptome landscape in Indian and French patients with severe alcoholic hepatitis and steroid responsiveness.

artículo científico publicado en 2017

Recent Advances in Practical Methods for Liver Cell Biology: A Short Overview

artículo científico publicado en 2020

Regulation of liver plasma membrane Ca2+ pump

artículo científico publicado en 1988

Reply: To PMID 23728734.

artículo científico publicado en 2013

Reversion of hepatic stellate cell to a quiescent phenotype: From myth to reality?

artículo científico publicado en 2013

Role of G protein beta gamma subunits in the regulation of the plasma membrane Ca2+ pump ⬇️

artículo científico publicado el 5 de febrero de 1992

Role of NF-kappaB in the antiproliferative effect of endothelin-1 and tumor necrosis factor-alpha in human hepatic stellate cells. Involvement of cyclooxygenase-2.

artículo científico publicado en 1998

Sphingosine 1-phosphate triggers both apoptotic and survival signals for human hepatic myofibroblasts

artículo científico publicado en 2002

Statins Modulate Cyclooxygenase-2 and Microsomal Prostaglandin E Synthase-1 in Human Hepatic Myofibroblasts

artículo científico publicado en 2015

Targeting cannabinoid receptors in hepatocellular carcinoma?

artículo científico publicado en 2016

Targeting the cannabinoid pathway limits the development of fibrosis and autoimmunity in a mouse model of systemic sclerosis

artículo científico publicado en 2010

The Cannabinoid Receptor 2 Protects Against Alcoholic Liver Disease Via a Macrophage Autophagy-Dependent Pathway

artículo científico publicado en 2016

The cannabinoid receptor type 2 promotes cardiac myocyte and fibroblast survival and protects against ischemia/reperfusion-induced cardiomyopathy

artículo científico publicado en 2009

The endocannabinoid system as a key mediator during liver diseases: new insights and therapeutic openings

artículo científico publicado en 2011

The epidermal growth factor receptor ligand amphiregulin participates in the development of mouse liver fibrosis.

artículo científico publicado en 2008

The high affinity (Ca2+-Mg2+)-ATPase in liver plasma membranes is a Ca2+ pump. Reconstitution of the purified enzyme into phospholipid vesicles

artículo científico publicado en 1987

The inhibitor of liver plasma membrane (Ca2+-Mg2+)-ATPase. Purification and identification as a mediator of glucagon action.

artículo científico publicado en 1985

The liver X receptor in hepatic stellate cells: a novel antifibrogenic target?

artículo científico publicado en 2011

The liver plasma membrane Ca-ATPase

artículo científico publicado en 1982

The metabolic syndrome and chronic liver disease

artículo científico

The sphingosine 1-phosphate receptor S1P2 triggers hepatic wound healing

artículo científico publicado en 2007

Type I interferon signaling in systemic immune cells from patients with alcoholic cirrhosis and its association with outcome.

artículo científico publicado en 2016

Upregulation of Epac-1 in Hepatic Stellate Cells by Prostaglandin E2 in Liver Fibrosis Is Associated with Reduced Fibrogenesis

artículo científico publicado en 2017

When autophagy chaperones liver metabolism

scientific article published on 01 September 2014

[Autophagy in chronic liver diseases: a friend rather than a foe?]

artículo científico publicado en 2017

[CB1 cannabinoid receptor antagonists: a novel approach for the treatment of liver fibrosis]

artículo científico publicado en 2006

[Calcium and cell death]

artículo científico publicado en 1987

[Endocannabinoids: therapeutic perspectives in chronic liver diseases]

artículo científico publicado en 2007

[Endothelins and their non-vascular effects]

artículo científico publicado en 1993

[Glucagon is processed to the (19-29) fragment at the level of the hepatocyte membrane]

artículo científico publicado en 1989

[The endocannabinoid system as a novel target for the treatment of liver fibrosis]

scientific article published on 06 April 2007

Guía para el uso y la interpretación de ensayos para el seguimiento de la autofagia (4ª edición)

artículo científico

Lista de obras de Sophie Lotersztajn

15-deoxy-Delta 12,14-prostaglandin J2 induces apoptosis of human hepatic myofibroblasts. A pathway involving oxidative stress independently of peroxisome-proliferator-activated receptors.

A defect in endothelial autophagy occurs in patients with non-alcoholic steatohepatitis and promotes inflammation and fibrosis

A glucagon fragment is responsible for the inhibition of the liver Ca2+ pump by glucagon

A high affinity calcium-stimulated magnesium-dependent ATPase in rat liver plasma membranes. Dependence of an endogenous protein activator distinct from calmodulin

A membrane-bound protein inhibitor of the high affinity Ca ATPase in rat liver plasma membranes

AJP-Cell Physiology begins a theme series on the control of the proteostasis network in health and diseases.

AJP-Cell begins a theme series on tissue fibrosis

AJP-cell begins a theme series on cellular mechanisms of endoplasmic reticulum stress signaling in health and disease

ASMase regulates autophagy and lysosomal membrane permeabilization and its inhibition prevents early stage non-alcoholic steatohepatitis

Activation of Na+/Ca2+ exchange by adenosine in ewe heart sarcolemma is mediated by a pertussis toxin-sensitive G protein

Adipose tissue macrophages: MR tracking to monitor obesity-associated inflammation

American Journal of Physiology-Cell Physiology initiates a series of articles around a theme: autophagy is the first theme

Antifibrogenic role of the cannabinoid receptor CB2 in the liver

Antiproliferative effects of ET-1 in human liver Ito cells: an ETB- and a cyclic AMP-mediated pathway

Aryl hydrocarbon receptor-dependent induction of liver fibrosis by dioxin

Autophagy in chronic liver diseases: the two faces of Janus

Autophagy in liver diseases: Time for translation?

Autophagy: a multifaceted partner in liver fibrosis

Beneficial paracrine effects of cannabinoid receptor 2 on liver injury and regeneration

Biological effects of C-type natriuretic peptide in human myofibroblastic hepatic stellate cells

Biological effects of sarafotoxin in rat liver

CB1 cannabinoid receptor antagonism: a new strategy for the treatment of liver fibrosis

Cannabinoid CB2 receptor potentiates obesity-associated inflammation, insulin resistance and hepatic steatosis

Cannabinoid CB2 receptors protect against alcoholic liver disease by regulating Kupffer cell polarization in mice

Cannabinoid receptor 2 counteracts interleukin-17-induced immune and fibrogenic responses in mouse liver

Cannabinoid receptors as new targets of antifibrosing strategies during chronic liver diseases

Cannabinoid receptors as novel therapeutic targets for the management of non-alcoholic steatohepatitis.

Cannabinoid receptors as therapeutic targets in the management of liver diseases

Cannabinoid signaling and liver therapeutics

Cellular targeting of the apoptosis-inducing compound gliotoxin to fibrotic rat livers.

Chronic Exposure to Low Doses of Dioxin Promotes Liver Fibrosis Development in the C57BL/6J Diet-Induced Obesity Mouse Model

Chronic hypocalcemia of vitamin D deficiency leads to lower intracellular calcium concentrations in rat hepatocytes

Cigarette smoke exposure: a novel cofactor of NAFLD progression?

Combination of CCl4 with alcoholic and metabolic injuries mimics human liver fibrosis

Coupling of endothelin B receptors to the calcium pump and phospholipase C via Gs and Gq in rat liver

Daily cannabis smoking as a risk factor for progression of fibrosis in chronic hepatitis C.

Daily cannabis use: a novel risk factor of steatosis severity in patients with chronic hepatitis C.

Elevated expression of osteopontin may be related to adipose tissue macrophage accumulation and liver steatosis in morbid obesity

Endocannabinoids and their role in fatty liver disease.

Endocannabinoids as novel mediators of liver diseases.

Endothelin inhibits the calcium pump and stimulates phosphoinositide phospholipase C in liver plasma membranes via two different G proteins, Gs and Gq

Endothelin-1 induces liver vasoconstriction through both ETA and ETB receptors

Endothelin-1 stimulates sphingosine kinase in human hepatic stellate cells. A novel role for sphingosine-1-P as a mediator of growth inhibition

Environmental factors as disease accelerators during chronic hepatitis C.

From the Editor's Desk…: December 2019

From the Editor's Desk…: November 2019

From the Editor's desk....: November 2018

From the Editor's desk....: September 2018

From the Editor's desk....: September 2018

Glucagon-(19-29) exerts a biphasic action on the liver plasma membrane Ca2+ pump which is mediated by G proteins.

Glucagon-(19-29), a Ca2+ pump inhibitory peptide, is processed from glucagon in the rat liver plasma membrane by a thiol endopeptidase

Gs mediates hormonal inhibition of the calcium pump in liver plasma membranes

Heme oxygenase-1 is an antifibrogenic protein in human hepatic myofibroblasts

Hepatic cytoprotection (5). Calcium and hepatotoxicity

Hepatic fibrosis: molecular mechanisms and drug targets

Homocysteine decreases endothelin-1 production by cultured human endothelial cells.

Human hepatic stellate cells are not permissive for hepatitis C virus entry and replication

Human liver plasma membrane Ca-ATPase: Identification and sensitivity to calcium antagonists ⬇️

Hyperactivation of anandamide synthesis and regulation of cell-cycle progression via cannabinoid type 1 (CB1) receptors in the regenerating liver

IRAP-dependent endosomal T cell receptor signalling is essential for T cell responses

Inhibition by glucagon of the calcium pump in liver plasma membranes.

Inhibition of monoacylglycerol lipase, an anti-inflammatory and antifibrogenic strategy in the liver

Inhibition of the calcium pump by human parathyroid hormone-(1-34) and human calcitonin in liver plasma membranes

Journal of Hepatology: The Home of Liver Research, 2015-2019

LC3-associated phagocytosis in myeloid cells, a fireman that restrains inflammation and liver fibrosis, via immunoreceptor inhibitory signalling

LC3-associated phagocytosis protects against inflammation and liver fibrosis via immunoreceptor inhibitory signaling

Lack of monoacylglycerol lipase prevents hepatic steatosis by favoring lipid storage in adipose tissue and intestinal malabsorption

Long term in vivo biotransformation of iron oxide nanoparticles

M2 Kupffer cells promote M1 Kupffer cell apoptosis: a protective mechanism against alcoholic and nonalcoholic fatty liver disease

M2 kupffer cells promote hepatocyte senescence: an IL-6-dependent protective mechanism against alcoholic liver disease

MAIT cell inhibition promotes liver fibrosis regression by reprogramming macrophage phenotype

Macrophage autophagy protects against liver fibrosis in mice

Molecular mechanisms regulating the antifibrogenic protein heme-oxygenase-1 in human hepatic myofibroblasts

Monoacylglycerol Lipase Inhibition Protects From Liver Injury in Mouse Models of Sclerosing Cholangitis

Mucosal-associated invariant T cells and disease

Mucosal-associated invariant T cells are a profibrogenic immune cell population in the liver.

New pieces in the complex puzzle of aberrant vacuolation. Focus on "Active vacuolar H+ ATPase and functional cycle of Rab5 are required for the vacuolation defect triggered by PtdIns(3,5)P2 loss under PIKfyve or Vps34 deficiency".

Novel role for carbohydrate responsive element binding protein in the control of ethanol metabolism and susceptibility to binge drinking

Oral methylthioadenosine administration attenuates fibrosis and chronic liver disease progression in Mdr2-/- mice