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Lista de obras de Justin Kale

After embedding in membranes antiapoptotic Bcl-XL protein binds both Bcl-2 homology region 3 and helix 1 of proapoptotic Bax protein to inhibit apoptotic mitochondrial permeabilization.

scientific article published on 10 March 2014

Allosteric Regulation of BH3 Proteins in Bcl-xL Complexes Enables Switch-like Activation of Bax

scientific article published on 27 January 2020

BCL-2 family proteins: changing partners in the dance towards death

artículo científico publicado en 2017

BDA-366, a putative Bcl-2 BH4 domain antagonist, induces apoptosis independently of Bcl-2 in a variety of cancer cell models

scientific article published on 17 September 2020

BH3-in-groove dimerization initiates and helix 9 dimerization expands Bax pore assembly in membranes

artículo científico publicado en 2015

Conformational Heterogeneity of Bax Helix 9 Dimer for Apoptotic Pore Formation

artículo científico publicado en 2016

Drugs targeting Bcl-2 family members as an emerging strategy in cancer

scientific article published on 08 September 2010

Examining the molecular mechanism of bcl-2 family proteins at membranes by fluorescence spectroscopy

artículo científico publicado en 2014

Mechanisms of action of Bcl-2 family proteins

artículo científico publicado en 2013

Phosphorylation switches Bax from promoting to inhibiting apoptosis thereby increasing drug resistance.

artículo científico publicado en 2018

Regulating cell death at, on, and in membranes.

artículo científico publicado en 2014

Shedding light on apoptosis at subcellular membranes

artículo científico publicado en 2012

Unleashing Blocked Apoptosis in Cancer Cells: New MCL1 Inhibitors Find Their Groove

artículo científico publicado en 2018

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