Lista de obras - José A Sánchez-Alcázar

Activation of the Mitochondrial Unfolded Protein Response: A New Therapeutic Target?

artículo científico publicado en 2022

Acute oxidant damage promoted on cancer cells by amitriptyline in comparison with some common chemotherapeutic drugs ⬇️

artículo científico publicado el 1 de noviembre de 2010

Aging-related changes in inflammatory and LKB1/AMPK gene expression in fibromyalgia patients.

artículo científico publicado en 2014

Amitriptyline induces coenzyme Q deficiency and oxidative damage in mouse lung and liver

scientific article published on 09 April 2011

Apoptotic cells subjected to cold/warming exposure disorganize apoptotic microtubule network and undergo secondary necrosis

artículo científico publicado en 2014

Apoptotic microtubule network organization and maintenance depend on high cellular ATP levels and energized mitochondria ⬇️

artículo científico publicado el 1 de abril de 2011

Apoptotic microtubules delimit an active caspase free area in the cellular cortex during the execution phase of apoptosis.

artículo científico publicado en 2013

Atherosclerosis and Coenzyme Q10

artículo científico publicado en 2019

Cell survival from chemotherapy depends on NF-kappaB transcriptional up-regulation of coenzyme Q biosynthesis.

artículo científico publicado en 2009

Cerebellar ataxia with coenzyme Q10 deficiency: Diagnosis and follow-up after coenzyme Q10 supplementation

Chemotherapy induces an increase in coenzyme Q10 levels in cancer cell lines.

artículo científico publicado en 2005

Clinical applications of coenzyme Q10.

artículo científico

Clinical, biochemical and molecular aspects of cerebellar ataxia and Coenzyme Q10 deficiency.

artículo científico publicado en 2007

Coenzyme Q(10): a novel therapeutic approach for Fibromyalgia? case series with 5 patients

artículo científico publicado en 2011

Coenzyme Q10 deficiency associated with a mitochondrial DNA depletion syndrome: a case report

scientific article published on 03 December 2008

Coenzyme Q10 distribution in blood is altered in patients with fibromyalgia.

artículo científico publicado en 2008

Coenzyme Q10: Novel Formulations and Medical Trends

artículo científico publicado en 2020

Coenzyme q10 regulates serotonin levels and depressive symptoms in fibromyalgia patients: results of a small clinical trial.

artículo científico publicado en 2014

Cyclooxygenase (COX) inhibitors induce apoptosis in non-small cell lung cancer through cyclooxygenase independent pathways.

artículo científico publicado en 2003

Cytotoxic effects of amitriptyline in human fibroblasts.

artículo científico publicado en 2007

Down regulation of the expression of mitochondrial phosphopantetheinyl-proteins in pantothenate kinase-associated neurodegeneration: pathophysiological consequences and therapeutic perspectives

artículo científico publicado en 2021

Dynamic Reorganization of the Cytoskeleton during Apoptosis: The Two Coffins Hypothesis

artículo científico publicado en 2017

Effects of Ethanol and Dexamethasone on Epidermis Examined by in Vitro 31P Magnetic Resonance Spectroscopy

artículo científico publicado en 1998

Emerging roles of apoptotic microtubules during the execution phase of apoptosis.

artículo científico

G Proteins Are Involved in the Suppression of Collagen α1(I) Gene Expression in Cultured Rat Hepatic Stellate Cells ⬇️

artículo científico publicado el 1 de marzo de 1998

Guidelines for the use and interpretation of assays for monitoring autophagy

artículo científico publicado en 2012

Increased mitochondrial cytochrome c levels and mitochondrial hyperpolarization precede camptothecin-induced apoptosis in Jurkat cells

artículo científico publicado en 2000

Is inflammation a mitochondrial dysfunction-dependent event in fibromyalgia?

artículo científico publicado en 2012

Laminin and integrin expression in the ventral ectodermal ridge of the mouse embryo: implications for regulation of BMP signalling.

artículo científico publicado en 2012

Metformin and caloric restriction induce an AMPK-dependent restoration of mitochondrial dysfunction in fibroblasts from Fibromyalgia patients.

artículo científico publicado en 2015

Missense mutation of the COQ2 gene causes defects of bioenergetics and de novo pyrimidine synthesis

scientific journal article

Mitochondrial dysfunction in skin biopsies and blood mononuclear cells from two cases of fibromyalgia patients.

artículo científico publicado en 2010

NLRP3 inflammasome is activated in mononuclear blood cells from patients with major depressive disorder

artículo científico publicado en 2014

Oral coenzyme Q10 supplementation improves clinical symptoms and recovers pathologic alterations in blood mononuclear cells in a fibromyalgia patient

artículo científico publicado en 2012

Oral treatment with amitriptyline induces coenzyme Q deficiency and oxidative stress in psychiatric patients.

artículo científico publicado en 2011

Oxidative stress correlates with headache symptoms in fibromyalgia: coenzyme Q₁₀ effect on clinical improvement

artículo científico publicado en 2012

Oxidative stress, mitochondrial dysfunction and, inflammation common events in skin of patients with Fibromyalgia

artículo científico publicado en 2015

PEGylated versus non-PEGylated magnetic nanoparticles as camptothecin delivery system.

artículo científico publicado en 2014

Pantothenate Rescues Iron Accumulation in Pantothenate Kinase-Associated Neurodegeneration Depending on the Type of Mutation

scientific article published on 01 September 2018

Pharmacological Chaperones and Coenzyme Q10 Treatment Improves Mutant β-Glucocerebrosidase Activity and Mitochondrial Function in Neuronopathic Forms of Gaucher Disease

artículo científico publicado en 2015

Precision Medicine in Rare Diseases

scientific article published on 13 November 2020

Reactive oxygen species mediate the down-regulation of mitochondrial transcripts and proteins by tumour necrosis factor-alpha in L929 cells.

artículo científico publicado en 2003

Recovery of MERRF fibroblasts and cybrids pathophysiology by coenzyme Q10.

artículo científico publicado en 2012

Screening of effective pharmacological treatments for MELAS syndrome using yeasts, fibroblasts and cybrid models of the disease

artículo científico publicado en 2012

Secondary coenzyme Q10 deficiency triggers mitochondria degradation by mitophagy in MELAS fibroblasts

artículo científico publicado en 2011

Stabilization of apoptotic cells: generation of zombie cells.

artículo científico publicado en 2014

Targeted delivery of pharmacological chaperones for Gaucher disease to macrophages by a mannosylated cyclodextrin carrier.

artículo científico publicado en 2014

The effect of maternal diabetes on the Wnt-PCP pathway during embryogenesis as reflected in the developing mouse eye.

artículo científico publicado en 2014

The hypoxic preconditioning agent deferoxamine induces poly(ADP-ribose) polymerase-1-dependent inhibition of the mitochondrial respiratory chain.

artículo científico publicado en 2011

Tumor Necrosis Factor-α Increases the Steady-state Reduction of Cytochromebof the Mitochondrial Respiratory Chain in Metabolically Inhibited L929 Cells

artículo científico publicado en 2000

Tumor necrosis factor alpha inhibits collagen alpha 1(I) gene expression in rat hepatic stellate cells through a G protein ⬇️

artículo científico publicado el 1 de agosto de 1997

Tumor necrosis factor-alpha increases ATP content in metabolically inhibited L929 cells preceding cell death.

artículo científico publicado en 1997

UPRmt activation improves pathological alterations in cellular models of mitochondrial diseases

artículo científico publicado en 2022

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

artículo científico publicado en 2016

Lista de obras de José A Sánchez-Alcázar

Activation of the Mitochondrial Unfolded Protein Response: A New Therapeutic Target?

Acute oxidant damage promoted on cancer cells by amitriptyline in comparison with some common chemotherapeutic drugs ⬇️

Aging-related changes in inflammatory and LKB1/AMPK gene expression in fibromyalgia patients.

Amitriptyline induces coenzyme Q deficiency and oxidative damage in mouse lung and liver

Apoptotic cells subjected to cold/warming exposure disorganize apoptotic microtubule network and undergo secondary necrosis

Apoptotic microtubule network organization and maintenance depend on high cellular ATP levels and energized mitochondria ⬇️

Apoptotic microtubules delimit an active caspase free area in the cellular cortex during the execution phase of apoptosis.

Atherosclerosis and Coenzyme Q10

Cell survival from chemotherapy depends on NF-kappaB transcriptional up-regulation of coenzyme Q biosynthesis.

Cerebellar ataxia with coenzyme Q10 deficiency: Diagnosis and follow-up after coenzyme Q10 supplementation

Chemotherapy induces an increase in coenzyme Q10 levels in cancer cell lines.

Clinical applications of coenzyme Q10.

Clinical, biochemical and molecular aspects of cerebellar ataxia and Coenzyme Q10 deficiency.

Coenzyme Q(10): a novel therapeutic approach for Fibromyalgia? case series with 5 patients

Coenzyme Q10 deficiency associated with a mitochondrial DNA depletion syndrome: a case report

Coenzyme Q10 distribution in blood is altered in patients with fibromyalgia.

Coenzyme Q10: Novel Formulations and Medical Trends

Coenzyme q10 regulates serotonin levels and depressive symptoms in fibromyalgia patients: results of a small clinical trial.

Cyclooxygenase (COX) inhibitors induce apoptosis in non-small cell lung cancer through cyclooxygenase independent pathways.

Cytotoxic effects of amitriptyline in human fibroblasts.

Down regulation of the expression of mitochondrial phosphopantetheinyl-proteins in pantothenate kinase-associated neurodegeneration: pathophysiological consequences and therapeutic perspectives

Dynamic Reorganization of the Cytoskeleton during Apoptosis: The Two Coffins Hypothesis

Effects of Ethanol and Dexamethasone on Epidermis Examined by in Vitro 31P Magnetic Resonance Spectroscopy

Emerging roles of apoptotic microtubules during the execution phase of apoptosis.

G Proteins Are Involved in the Suppression of Collagen α1(I) Gene Expression in Cultured Rat Hepatic Stellate Cells ⬇️

Guidelines for the use and interpretation of assays for monitoring autophagy

Increased mitochondrial cytochrome c levels and mitochondrial hyperpolarization precede camptothecin-induced apoptosis in Jurkat cells

Is inflammation a mitochondrial dysfunction-dependent event in fibromyalgia?

Laminin and integrin expression in the ventral ectodermal ridge of the mouse embryo: implications for regulation of BMP signalling.

Metformin and caloric restriction induce an AMPK-dependent restoration of mitochondrial dysfunction in fibroblasts from Fibromyalgia patients.

Missense mutation of the COQ2 gene causes defects of bioenergetics and de novo pyrimidine synthesis

Mitochondrial dysfunction in skin biopsies and blood mononuclear cells from two cases of fibromyalgia patients.

NLRP3 inflammasome is activated in mononuclear blood cells from patients with major depressive disorder

Oral coenzyme Q10 supplementation improves clinical symptoms and recovers pathologic alterations in blood mononuclear cells in a fibromyalgia patient

Oral treatment with amitriptyline induces coenzyme Q deficiency and oxidative stress in psychiatric patients.

Oxidative stress correlates with headache symptoms in fibromyalgia: coenzyme Q₁₀ effect on clinical improvement

Oxidative stress, mitochondrial dysfunction and, inflammation common events in skin of patients with Fibromyalgia

PEGylated versus non-PEGylated magnetic nanoparticles as camptothecin delivery system.

Pantothenate Rescues Iron Accumulation in Pantothenate Kinase-Associated Neurodegeneration Depending on the Type of Mutation

Pharmacological Chaperones and Coenzyme Q10 Treatment Improves Mutant β-Glucocerebrosidase Activity and Mitochondrial Function in Neuronopathic Forms of Gaucher Disease

Precision Medicine in Rare Diseases

Reactive oxygen species mediate the down-regulation of mitochondrial transcripts and proteins by tumour necrosis factor-alpha in L929 cells.

Recovery of MERRF fibroblasts and cybrids pathophysiology by coenzyme Q10.

Screening of effective pharmacological treatments for MELAS syndrome using yeasts, fibroblasts and cybrid models of the disease

Secondary coenzyme Q10 deficiency triggers mitochondria degradation by mitophagy in MELAS fibroblasts

Stabilization of apoptotic cells: generation of zombie cells.

Targeted delivery of pharmacological chaperones for Gaucher disease to macrophages by a mannosylated cyclodextrin carrier.

The effect of maternal diabetes on the Wnt-PCP pathway during embryogenesis as reflected in the developing mouse eye.

The hypoxic preconditioning agent deferoxamine induces poly(ADP-ribose) polymerase-1-dependent inhibition of the mitochondrial respiratory chain.

Tumor Necrosis Factor-α Increases the Steady-state Reduction of Cytochromebof the Mitochondrial Respiratory Chain in Metabolically Inhibited L929 Cells

Tumor necrosis factor alpha inhibits collagen alpha 1(I) gene expression in rat hepatic stellate cells through a G protein ⬇️

Tumor necrosis factor-alpha increases ATP content in metabolically inhibited L929 cells preceding cell death.

UPRmt activation improves pathological alterations in cellular models of mitochondrial diseases

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)