Lista de obras - Melanie Königshoff - Dominio Público Uruguay

'WNT-er is coming': WNT signalling in chronic lung diseases.

artículo científico publicado en 2017

A drug screen with approved compounds identifies amlexanox as a novel Wnt/β-catenin activator inducing lung epithelial organoid formation

artículo científico publicado en 2021

An ex vivo model to induce early fibrosis-like changes in human precision-cut lung slices.

artículo científico publicado en 2017

Applications and Approaches for 3D Precision-cut Lung Slices: Disease Modeling and Drug Discovery

scientific article published on 28 January 2020

Breaking the In Vitro Barrier in Respiratory Medicine: Engineered Microphysiological Systems for COPD and Beyond

artículo científico publicado en 2017

Cell-surface phenotyping identifies CD36 and CD97 as novel markers of fibroblast quiescence in lung fibrosis

artículo científico publicado en 2018

Correction: Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD.

artículo científico publicado en 2017

Differential effects of Nintedanib and Pirfenidone on lung alveolar epithelial cell function in ex vivo murine and human lung tissue cultures of pulmonary fibrosis

article

Distinct niches within the extracellular matrix dictate fibroblast function in (cell-free) 3D lung tissue cultures.

artículo científico publicado en 2018

Embedding of Precision-Cut Lung Slices in Engineered Hydrogel Biomaterials Supports Extended Ex Vivo Culture

artículo científico publicado en 2020

Functional role and species-specific contribution of arginases in pulmonary fibrosis

artículo científico publicado en 2007

Hyperoxia Injury in the Developing Lung is Mediated by Mesenchymal Expression of Wnt5A

artículo científico publicado en 2020

Impairment of Immunoproteasome Function by Cigarette Smoke and in Chronic Obstructive Pulmonary Disease

artículo científico publicado en 2016

Increased Extracellular Vesicles Mediate WNT-5A Signaling in Idiopathic Pulmonary Fibrosis

scientific article published on 25 July 2018

Increased expression of 5-hydroxytryptamine2A/B receptors in idiopathic pulmonary fibrosis: a rationale for therapeutic intervention

artículo científico publicado en 2010

Inhibition of LTβR signalling activates WNT-induced regeneration in lung

artículo científico publicado en 2020

Listen to the WNT; It Talks: WNT7A Drives Epithelial–Mesenchymal Cross-Talk within the Fibrotic Niche in Idiopathic Pulmonary Fibrosis

scientific article published in 2023

Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD

artículo científico publicado en 2016

Phenotypic drug screening in a human fibrosis model identified a novel class of antifibrotic therapeutics

artículo científico publicado en 2021

Phosphodiesterase 6 subunits are expressed and altered in idiopathic pulmonary fibrosis.

artículo científico publicado en 2010

Preclinical validation and imaging of Wnt-induced repair in human 3D lung tissue cultures.

artículo científico publicado en 2015

Publisher Correction: Inhibition of LTβR signalling activates WNT-induced regeneration in lung

artículo científico publicado en 2020

Reduced Frizzled Receptor 4 Expression Prevents WNT/β-Catenin-driven Alveolar Lung Repair in Chronic Obstructive Pulmonary Disease.

artículo científico publicado en 2017

Senolytic drugs target alveolar epithelial cell function and attenuate experimental lung fibrosis ex vivo

artículo científico

Single-cell RNA sequencing identifies G-protein coupled receptor 87 as a basal cell marker expressed in distal honeycomb cysts in idiopathic pulmonary fibrosis

artículo científico publicado en 2022

The Oncogene ECT2 Contributes to a Hyperplastic, Proliferative Lung Epithelial Cell Phenotype in Idiopathic Pulmonary Fibrosis

scientific article published on 01 December 2019

The role of dimethylarginine dimethylaminohydrolase in idiopathic pulmonary fibrosis

artículo científico publicado en 2011

Thrombin impairs alveolar fluid clearance by promoting endocytosis of Na+,K+-ATPase

artículo científico publicado en 2005

Towards a global initiative for fibrosis treatment (GIFT).

artículo científico publicado en 2017

WNT Signaling in Lung Aging and Disease.

artículo científico publicado en 2016

Wnt/β-catenin signaling is critical for regenerative potential of distal lung epithelial progenitor cells in homeostasis and emphysema

artículo científico publicado en 2020

Lista de obras de Melanie Königshoff

'WNT-er is coming': WNT signalling in chronic lung diseases.

A drug screen with approved compounds identifies amlexanox as a novel Wnt/β-catenin activator inducing lung epithelial organoid formation

An ex vivo model to induce early fibrosis-like changes in human precision-cut lung slices.

Applications and Approaches for 3D Precision-cut Lung Slices: Disease Modeling and Drug Discovery

Breaking the In Vitro Barrier in Respiratory Medicine: Engineered Microphysiological Systems for COPD and Beyond

Cell-surface phenotyping identifies CD36 and CD97 as novel markers of fibroblast quiescence in lung fibrosis

Correction: Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD.

Differential effects of Nintedanib and Pirfenidone on lung alveolar epithelial cell function in ex vivo murine and human lung tissue cultures of pulmonary fibrosis

Distinct niches within the extracellular matrix dictate fibroblast function in (cell-free) 3D lung tissue cultures.

Embedding of Precision-Cut Lung Slices in Engineered Hydrogel Biomaterials Supports Extended Ex Vivo Culture

Functional role and species-specific contribution of arginases in pulmonary fibrosis

Hyperoxia Injury in the Developing Lung is Mediated by Mesenchymal Expression of Wnt5A

Impairment of Immunoproteasome Function by Cigarette Smoke and in Chronic Obstructive Pulmonary Disease

Increased Extracellular Vesicles Mediate WNT-5A Signaling in Idiopathic Pulmonary Fibrosis

Increased expression of 5-hydroxytryptamine2A/B receptors in idiopathic pulmonary fibrosis: a rationale for therapeutic intervention

Inhibition of LTβR signalling activates WNT-induced regeneration in lung

Listen to the WNT; It Talks: WNT7A Drives Epithelial–Mesenchymal Cross-Talk within the Fibrotic Niche in Idiopathic Pulmonary Fibrosis

Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD

Phenotypic drug screening in a human fibrosis model identified a novel class of antifibrotic therapeutics

Phosphodiesterase 6 subunits are expressed and altered in idiopathic pulmonary fibrosis.

Preclinical validation and imaging of Wnt-induced repair in human 3D lung tissue cultures.

Publisher Correction: Inhibition of LTβR signalling activates WNT-induced regeneration in lung

Reduced Frizzled Receptor 4 Expression Prevents WNT/β-Catenin-driven Alveolar Lung Repair in Chronic Obstructive Pulmonary Disease.

Senolytic drugs target alveolar epithelial cell function and attenuate experimental lung fibrosis ex vivo

Single-cell RNA sequencing identifies G-protein coupled receptor 87 as a basal cell marker expressed in distal honeycomb cysts in idiopathic pulmonary fibrosis

The Oncogene ECT2 Contributes to a Hyperplastic, Proliferative Lung Epithelial Cell Phenotype in Idiopathic Pulmonary Fibrosis

The role of dimethylarginine dimethylaminohydrolase in idiopathic pulmonary fibrosis

Thrombin impairs alveolar fluid clearance by promoting endocytosis of Na+,K+-ATPase

Towards a global initiative for fibrosis treatment (GIFT).

WNT Signaling in Lung Aging and Disease.

Wnt/β-catenin signaling is critical for regenerative potential of distal lung epithelial progenitor cells in homeostasis and emphysema