Lista de obras - Dag Sehlin - Dominio Público Uruguay

A bispecific Tribody PET radioligand for visualization of amyloid-beta protofibrils - a new concept for neuroimaging

artículo científico publicado en 2017

An amyloid-beta protofibril-selective antibody prevents amyloid formation in a mouse model of Alzheimer's disease

artículo científico publicado en 2009

Antibody-based PET imaging of amyloid beta in mouse models of Alzheimer's disease

artículo científico

Apolipoprotein E increases cell association of amyloid-β 40 through heparan sulfate and LRP1 dependent pathways

artículo científico publicado en 2014

Astroglial Responses to Amyloid-Beta Progression in a Mouse Model of Alzheimer's Disease

artículo científico publicado en 2018

Bivalent Brain Shuttle Increases Antibody Uptake by Monovalent Binding to the Transferrin Receptor.

artículo científico publicado en 2017

Brain mGluR5 in mice with amyloid beta pathology studied with in vivo [11C]ABP688 PET imaging and ex vivo immunoblotting.

artículo científico publicado en 2016

Brain pharmacokinetics of two BBB penetrating bispecific antibodies of different size

artículo científico publicado en 2021

Brain tissue Aβ42 levels are linked to shunt response in idiopathic normal pressure hydrocephalus

artículo científico publicado en 2018

Cationization increases brain distribution of an amyloid-beta protofibril selective F(ab')2 fragment.

artículo científico publicado en 2017

Delineating Amyloid Plaque Associated Neuronal Sphingolipids in Transgenic Alzheimer's Disease Mice (tgArcSwe) Using MALDI Imaging Mass Spectrometry.

artículo científico publicado en 2016

Efficient and inexpensive transient expression of multispecific multivalent antibodies in Expi293 cells.

artículo científico publicado en 2017

Efficient clearance of Aβ protofibrils in AβPP-transgenic mice treated with a brain-penetrating bifunctional antibody.

artículo científico publicado en 2018

Fluorine-18-Labeled Antibody Ligands for PET Imaging of Amyloid-β in Brain

artículo científico publicado en 2020

Functionalization of Radiolabeled Antibodies to Enhance Peripheral Clearance for High Contrast Brain Imaging

artículo científico publicado en 2022

Heavy-Chain Complementarity-Determining Regions Determine Conformation Selectivity of Anti-Aβ Antibodies

scientific article published on 13 August 2010

Heterogeneous drug tissue binding in brain regions of rats, Alzheimer's patients and controls: impact on translational drug development

article

Increased Number of Plasma B Cells Producing Autoantibodies Against Aβ42 Protofibrils in Alzheimer's Disease.

artículo científico publicado en 2015

Increased inflammatory response in cytomegalovirus seropositive patients with Alzheimer's disease

artículo científico publicado en 2014

Interference from heterophilic antibodies in amyloid-β oligomer ELISAs

artículo científico publicado en 2010

Large aggregates are the major soluble Aβ species in AD brain fractionated with density gradient ultracentrifugation

artículo científico publicado en 2012

Novel multivalent design of a monoclonal antibody improves binding strength to soluble aggregates of amyloid beta

artículo científico publicado en 2021

Perspectives on future Alzheimer therapies: amyloid-β protofibrils - a new target for immunotherapy with BAN2401 in Alzheimer's disease

artículo científico

Pharmacokinetics, biodistribution and brain retention of a bispecific antibody-based PET radioligand for imaging of amyloid-β.

artículo científico publicado en 2017

SPECT imaging of distribution and retention of a brain-penetrating bispecific amyloid-β antibody in a mouse model of Alzheimer's disease

scientific article published on 21 September 2020

Sensitive detection of Aβ protofibrils by proximity ligation--relevance for Alzheimer's disease

artículo científico publicado en 2010

Specific uptake of an amyloid-β protofibril-binding antibody-tracer in AβPP transgenic mouse brain.

artículo científico publicado en 2013

The Aβ protofibril selective antibody mAb158 prevents accumulation of Aβ in astrocytes and rescues neurons from Aβ-induced cell death.

artículo científico publicado en 2018

Lista de obras de Dag Sehlin

A bispecific Tribody PET radioligand for visualization of amyloid-beta protofibrils - a new concept for neuroimaging

An amyloid-beta protofibril-selective antibody prevents amyloid formation in a mouse model of Alzheimer's disease

Antibody-based PET imaging of amyloid beta in mouse models of Alzheimer's disease

Apolipoprotein E increases cell association of amyloid-β 40 through heparan sulfate and LRP1 dependent pathways

Astroglial Responses to Amyloid-Beta Progression in a Mouse Model of Alzheimer's Disease

Bivalent Brain Shuttle Increases Antibody Uptake by Monovalent Binding to the Transferrin Receptor.

Brain mGluR5 in mice with amyloid beta pathology studied with in vivo [11C]ABP688 PET imaging and ex vivo immunoblotting.

Brain pharmacokinetics of two BBB penetrating bispecific antibodies of different size

Brain tissue Aβ42 levels are linked to shunt response in idiopathic normal pressure hydrocephalus

Cationization increases brain distribution of an amyloid-beta protofibril selective F(ab')2 fragment.

Delineating Amyloid Plaque Associated Neuronal Sphingolipids in Transgenic Alzheimer's Disease Mice (tgArcSwe) Using MALDI Imaging Mass Spectrometry.

Efficient and inexpensive transient expression of multispecific multivalent antibodies in Expi293 cells.

Efficient clearance of Aβ protofibrils in AβPP-transgenic mice treated with a brain-penetrating bifunctional antibody.

Fluorine-18-Labeled Antibody Ligands for PET Imaging of Amyloid-β in Brain

Functionalization of Radiolabeled Antibodies to Enhance Peripheral Clearance for High Contrast Brain Imaging

Heavy-Chain Complementarity-Determining Regions Determine Conformation Selectivity of Anti-Aβ Antibodies

Heterogeneous drug tissue binding in brain regions of rats, Alzheimer's patients and controls: impact on translational drug development

Increased Number of Plasma B Cells Producing Autoantibodies Against Aβ42 Protofibrils in Alzheimer's Disease.

Increased inflammatory response in cytomegalovirus seropositive patients with Alzheimer's disease

Interference from heterophilic antibodies in amyloid-β oligomer ELISAs

Large aggregates are the major soluble Aβ species in AD brain fractionated with density gradient ultracentrifugation

Novel multivalent design of a monoclonal antibody improves binding strength to soluble aggregates of amyloid beta

Perspectives on future Alzheimer therapies: amyloid-β protofibrils - a new target for immunotherapy with BAN2401 in Alzheimer's disease

Pharmacokinetics, biodistribution and brain retention of a bispecific antibody-based PET radioligand for imaging of amyloid-β.

SPECT imaging of distribution and retention of a brain-penetrating bispecific amyloid-β antibody in a mouse model of Alzheimer's disease

Sensitive detection of Aβ protofibrils by proximity ligation--relevance for Alzheimer's disease

Specific uptake of an amyloid-β protofibril-binding antibody-tracer in AβPP transgenic mouse brain.

The Aβ protofibril selective antibody mAb158 prevents accumulation of Aβ in astrocytes and rescues neurons from Aβ-induced cell death.