Lista de obras - Julio Vera - Dominio Público Uruguay

14-3-3sigma gene silencing during melanoma progression and its role in cell cycle control and cellular senescence.

artículo científico publicado en 2009

A gene regulatory architecture that controls region-independent dynamics of oligodendrocyte differentiation

scientific article published on 07 February 2019

A model-based strategy to investigate the role of microRNA regulation in cancer signalling networks

artículo científico publicado en 2010

A multi-level model accounting for the effects of JAK2-STAT5 signal modulation in erythropoiesis

artículo científico publicado en 2009

A new semisynthetic cardenolide analog 3β-[2-(1-amantadine)- 1-on-ethylamine]-digitoxigenin (AMANTADIG) affects G2/M cell cycle arrest and miRNA expression profiles and enhances proapoptotic survivin-2B expression in renal cell carcinoma cell lines.

artículo científico publicado en 2017

A system biology approach to understand functional activity of cell communication systems

artículo científico publicado en 2008

A systems biology approach to analyse amplification in the JAK2-STAT5 signalling pathway

artículo científico publicado en 2008

A systems' biology approach to study microRNA-mediated gene regulatory networks

artículo científico publicado en 2013

A web platform for the network analysis of highthroughput data in melanoma and its use to investigate mechanisms of resistance to anti-PD1 immunotherapy.

artículo científico publicado en 2018

An Interactive Macrophage Signal Transduction Map Facilitates Comparative Analyses of High-Throughput Data.

artículo científico publicado en 2017

Analysis of cell adhesion during early stages of colon cancer based on an extended multi-valued logic approach

artículo científico publicado en 2012

Baccoside A suppresses epileptic-like seizure/convulsion in Caenorhabditis elegans

Bacterial Adherence and Dwelling Probability: Two Drivers of Early Alveolar Infection by Streptococcus pneumoniae Identified in Multi-Level Mathematical Modeling.

artículo científico publicado en 2018

Biochemical pathway modeling tools for drug target detection in cancer and other complex diseases.

artículo científico publicado en 2011

Can Gamification Contribute to Computer Modeling-Driven Biomedical Research?

artículo científico publicado en 2018

Computational analysis and modeling the effectiveness of 'Zanamivir' targeting neuraminidase protein in pandemic H1N1 strains

artículo científico publicado en 2011

Computational analysis of target hub gene repression regulated by multiple and cooperative miRNAs

artículo científico publicado en 2012

Cooperative gene regulation by microRNA pairs and their identification using a computational workflow

artículo científico publicado en 2014

Corrigendum: Multiplicity of Mathematical Modeling Strategies to Search for Molecular and Cellular Insights into Bacteria Lung Infection.

artículo científico publicado en 2017

Design of metabolic engineering strategies for maximizing L-(-)-carnitine production by Escherichia coli. Integration of the metabolic and bioreactor levels.

artículo científico publicado en 2005

Detection and Analysis of Critical Dynamic Properties of Oligodendrocyte Differentiation

artículo científico publicado en 2022

Detection of potential enzyme targets by metabolic modelling and optimization: application to a simple enzymopathy

artículo científico publicado en 2007

Dissecting Long-Term Glucose Metabolism Identifies New Susceptibility Period for Metabolic Dysfunction in Aged Mice

artículo científico publicado en 2015

Dynamic energy budget approaches for modelling organismal ageing

artículo científico publicado en 2010

Dynamic properties of a delayed protein cross talk model

artículo científico publicado en 2007

Dynamical effects of epigenetic silencing of 14-3-3sigma expression

artículo científico publicado en 2009

Dynamics of receptor and protein transducer homodimerisation

artículo científico publicado en 2008

Electroporated Antigen-Encoding mRNA Is Not a Danger Signal to Human Mature Monocyte-Derived Dendritic Cells.

artículo científico publicado en 2015

Emerging functional markers for cancer stem cell-based therapies: Understanding signaling networks for targeting metastasis

artículo científico publicado en 2018

Exploration of homodimer receptor: homodimer protein interactions.

artículo científico

Genome-wide Chromatin Profiling of Legionella pneumophila-Infected Human Macrophages Reveals Activation of the Probacterial Host Factor TNFAIP2.

artículo científico publicado en 2016

Glaucoma-TrEl: A web-based interactive database to build evidence-based hypotheses on the role of trace elements in glaucoma

artículo científico publicado en 2022

Growth and ligninolytic system production dynamics of the Phanerochaete chrysosporium fungus A modelling and optimization approach.

artículo científico publicado en 2008

Heterogeneous fate choice of genetically modulated adult neural stem cells in gray and white matter of the central nervous system

artículo científico publicado en 2019

Hybrid modeling of the crosstalk between signaling and transcriptional networks using ordinary differential equations and multi-valued logic

artículo científico publicado en 2013

Identification of immunogenic consensus T-cell epitopes in globally distributed influenza-A H1N1 neuraminidase

scientific article published in 2011

Identification of miRNA-mRNA Modules in Colorectal Cancer Using Rough Hypercuboid Based Supervised Clustering

artículo científico publicado en 2017

In silico approaches and the role of ontologies in aging research

artículo científico publicado en 2013

Integration of sensitivity and bifurcation analysis to detect critical processes in a model combining signalling and cell population dynamics

article

Investigating dynamics of inhibitory and feedback loops in ERK signalling using power-law models

artículo científico publicado en 2010

Kinetic modeling-based detection of genetic signatures that provide chemoresistance via the E2F1-p73/DNp73-miR-205 network

artículo científico publicado en 2013

MetMAP: an integrated Matlab package for analysis and optimization of metabolic systems

scientific article published on 01 January 2004

MiR-205-5p and miR-342-3p cooperate in the repression of the E2F1 transcription factor in the context of anticancer chemotherapy resistance.

artículo científico publicado en 2018

MicroRNA-Regulated Networks: The Perfect Storm for Classical Molecular Biology, the Ideal Scenario for Systems Biology ⬇️

artículo científico publicado el 1 de enero de 2013

MicroRNAs Constitute a Negative Feedback Loop in Streptococcus pneumoniae-Induced Macrophage Activation.

artículo científico publicado en 2016

Model based optimization of biochemical systems using multiple objectives: a comparison of several solution strategies

Model-based genotype-phenotype mapping used to investigate gene signatures of immune sensitivity and resistance in melanoma micrometastasis

artículo científico

Model-based investigation of the transcriptional activity of p53 and its feedback loop regulation via 14-3-3σ.

artículo científico publicado en 2011

Modeling miRNA Regulation in Cancer Signaling Systems: miR-34a Regulation of the p53/Sirt1 Signaling Module ⬇️

artículo científico publicado el 1 de enero de 2012

Multicriteria optimization of biochemical systems by linear programming: application to production of ethanol by Saccharomyces cerevisiae

artículo científico publicado en 2003

Multiplicity of Mathematical Modeling Strategies to Search for Molecular and Cellular Insights into Bacteria Lung Infection.

artículo científico publicado en 2017

Non-coding RNA detection methods combined to improve usability, reproducibility and precision

artículo científico publicado en 2010

PLMaddon: a power-law module for the Matlab SBToolbox

artículo científico publicado en 2007

Personalized cancer immunotherapy using Systems Medicine approaches

artículo científico

Power-law models of signal transduction pathways

artículo científico publicado en 2007

Role of inhibitory proteins as modulators of oscillations in NFB signalling

artículo científico publicado en 2009

Rough hypercuboid based supervised clustering of miRNAs.

artículo científico publicado en 2015

SBML export interface for the systems biology toolbox for MATLAB.

artículo científico publicado en 2007

Serum levels of miR-320 family members are associated with clinical parameters and diagnosis in prostate cancer patients.

artículo científico publicado en 2017

Systems Biology and Bioinformatics in Aging Research: A Workshop Report

Systems Medicine for Lung Diseases: Phenotypes and Precision Medicine in Cancer, Infection, and Allergy

artículo científico

Systems biologists seek fuller integration of systems biology approaches in new cancer research programs

artículo científico publicado en 2009

Systems biology approaches in aging research.

artículo científico publicado en 2014

Systems biology of JAK-STAT signalling in human malignancies

artículo científico publicado en 2011

Systems biology-based investigation of cooperating microRNAs as monotherapy or adjuvant therapy in cancer

artículo científico publicado en 2019

THP-1-derived macrophages render lung epithelial cells hypo-responsive to Legionella pneumophila - a systems biology study.

artículo científico publicado en 2017

The AP-1 Transcription Factor c-Jun Promotes Arthritis by Regulating Cyclooxygenase-2 and Arginase-1 Expression in Macrophages.

artículo científico

The RNA world in the 21st century-a systems approach to finding non-coding keys to clinical questions.

artículo científico

The Role of Age, Neutrophil Infiltration and Antibiotics Timing in the Severity of Streptococcus pneumoniae Pneumonia. Insights from a Multi-Level Mathematical Model Approach

artículo científico publicado en 2020

The Role of Immune Checkpoint Blockade in Uveal Melanoma

artículo científico publicado en 2020

The systems biology of mitochondrial fission and fusion and implications for disease and aging

artículo científico

Third-Kind Encounters in Biomedicine: Immunology Meets Mathematics and Informatics to Become Quantitative and Predictive.

artículo científico publicado en 2016

Transcription factor Sox10 regulates oligodendroglial Sox9 levels via microRNAs

artículo científico publicado en 2017

Transcriptional Profiling of Ligand Expression in Cell Specific Populations of the Adult Mouse Forebrain That Regulates Neurogenesis.

artículo científico publicado en 2018

Transcriptional analysis identifies potential biomarkers and molecular regulators in pneumonia and COPD exacerbation

scientific article published on 14 January 2020

Tumors as chaotic attractors

artículo científico publicado en 2014

Understanding microRNA-mediated gene regulatory networks through mathematical modelling.

artículo científico publicado en 2016

Unraveling a tumor type-specific regulatory core underlying E2F1-mediated epithelial-mesenchymal transition to predict receptor protein signatures

artículo científico publicado en 2017

Whither systems medicine?

artículo científico publicado en 2018

miR-638 promotes melanoma metastasis and protects melanoma cells from apoptosis and autophagy.

artículo científico publicado en 2015

Lista de obras de Julio Vera

14-3-3sigma gene silencing during melanoma progression and its role in cell cycle control and cellular senescence.

A gene regulatory architecture that controls region-independent dynamics of oligodendrocyte differentiation

A model-based strategy to investigate the role of microRNA regulation in cancer signalling networks

A multi-level model accounting for the effects of JAK2-STAT5 signal modulation in erythropoiesis

A new semisynthetic cardenolide analog 3β-[2-(1-amantadine)- 1-on-ethylamine]-digitoxigenin (AMANTADIG) affects G2/M cell cycle arrest and miRNA expression profiles and enhances proapoptotic survivin-2B expression in renal cell carcinoma cell lines.

A system biology approach to understand functional activity of cell communication systems

A systems biology approach to analyse amplification in the JAK2-STAT5 signalling pathway

A systems' biology approach to study microRNA-mediated gene regulatory networks

A web platform for the network analysis of highthroughput data in melanoma and its use to investigate mechanisms of resistance to anti-PD1 immunotherapy.

An Interactive Macrophage Signal Transduction Map Facilitates Comparative Analyses of High-Throughput Data.

Analysis of cell adhesion during early stages of colon cancer based on an extended multi-valued logic approach

Baccoside A suppresses epileptic-like seizure/convulsion in Caenorhabditis elegans

Bacterial Adherence and Dwelling Probability: Two Drivers of Early Alveolar Infection by Streptococcus pneumoniae Identified in Multi-Level Mathematical Modeling.

Biochemical pathway modeling tools for drug target detection in cancer and other complex diseases.

Can Gamification Contribute to Computer Modeling-Driven Biomedical Research?

Computational analysis and modeling the effectiveness of 'Zanamivir' targeting neuraminidase protein in pandemic H1N1 strains

Computational analysis of target hub gene repression regulated by multiple and cooperative miRNAs

Cooperative gene regulation by microRNA pairs and their identification using a computational workflow

Corrigendum: Multiplicity of Mathematical Modeling Strategies to Search for Molecular and Cellular Insights into Bacteria Lung Infection.

Design of metabolic engineering strategies for maximizing L-(-)-carnitine production by Escherichia coli. Integration of the metabolic and bioreactor levels.

Detection and Analysis of Critical Dynamic Properties of Oligodendrocyte Differentiation

Detection of potential enzyme targets by metabolic modelling and optimization: application to a simple enzymopathy

Dissecting Long-Term Glucose Metabolism Identifies New Susceptibility Period for Metabolic Dysfunction in Aged Mice

Dynamic energy budget approaches for modelling organismal ageing

Dynamic properties of a delayed protein cross talk model

Dynamical effects of epigenetic silencing of 14-3-3sigma expression

Dynamics of receptor and protein transducer homodimerisation

Electroporated Antigen-Encoding mRNA Is Not a Danger Signal to Human Mature Monocyte-Derived Dendritic Cells.

Emerging functional markers for cancer stem cell-based therapies: Understanding signaling networks for targeting metastasis

Exploration of homodimer receptor: homodimer protein interactions.

Genome-wide Chromatin Profiling of Legionella pneumophila-Infected Human Macrophages Reveals Activation of the Probacterial Host Factor TNFAIP2.

Glaucoma-TrEl: A web-based interactive database to build evidence-based hypotheses on the role of trace elements in glaucoma

Growth and ligninolytic system production dynamics of the Phanerochaete chrysosporium fungus A modelling and optimization approach.

Heterogeneous fate choice of genetically modulated adult neural stem cells in gray and white matter of the central nervous system

Hybrid modeling of the crosstalk between signaling and transcriptional networks using ordinary differential equations and multi-valued logic

Identification of immunogenic consensus T-cell epitopes in globally distributed influenza-A H1N1 neuraminidase

Identification of miRNA-mRNA Modules in Colorectal Cancer Using Rough Hypercuboid Based Supervised Clustering

In silico approaches and the role of ontologies in aging research

Integration of sensitivity and bifurcation analysis to detect critical processes in a model combining signalling and cell population dynamics

Investigating dynamics of inhibitory and feedback loops in ERK signalling using power-law models

Kinetic modeling-based detection of genetic signatures that provide chemoresistance via the E2F1-p73/DNp73-miR-205 network

MetMAP: an integrated Matlab package for analysis and optimization of metabolic systems

MiR-205-5p and miR-342-3p cooperate in the repression of the E2F1 transcription factor in the context of anticancer chemotherapy resistance.

MicroRNA-Regulated Networks: The Perfect Storm for Classical Molecular Biology, the Ideal Scenario for Systems Biology ⬇️

MicroRNAs Constitute a Negative Feedback Loop in Streptococcus pneumoniae-Induced Macrophage Activation.

Model based optimization of biochemical systems using multiple objectives: a comparison of several solution strategies

Model-based genotype-phenotype mapping used to investigate gene signatures of immune sensitivity and resistance in melanoma micrometastasis

Model-based investigation of the transcriptional activity of p53 and its feedback loop regulation via 14-3-3σ.

Modeling miRNA Regulation in Cancer Signaling Systems: miR-34a Regulation of the p53/Sirt1 Signaling Module ⬇️

Multicriteria optimization of biochemical systems by linear programming: application to production of ethanol by Saccharomyces cerevisiae

Multiplicity of Mathematical Modeling Strategies to Search for Molecular and Cellular Insights into Bacteria Lung Infection.

Non-coding RNA detection methods combined to improve usability, reproducibility and precision

PLMaddon: a power-law module for the Matlab SBToolbox

Personalized cancer immunotherapy using Systems Medicine approaches

Power-law models of signal transduction pathways

Role of inhibitory proteins as modulators of oscillations in NFB signalling

Rough hypercuboid based supervised clustering of miRNAs.

SBML export interface for the systems biology toolbox for MATLAB.

Serum levels of miR-320 family members are associated with clinical parameters and diagnosis in prostate cancer patients.

Systems Biology and Bioinformatics in Aging Research: A Workshop Report

Systems Medicine for Lung Diseases: Phenotypes and Precision Medicine in Cancer, Infection, and Allergy

Systems biologists seek fuller integration of systems biology approaches in new cancer research programs

Systems biology approaches in aging research.

Systems biology of JAK-STAT signalling in human malignancies

Systems biology-based investigation of cooperating microRNAs as monotherapy or adjuvant therapy in cancer

THP-1-derived macrophages render lung epithelial cells hypo-responsive to Legionella pneumophila - a systems biology study.

The AP-1 Transcription Factor c-Jun Promotes Arthritis by Regulating Cyclooxygenase-2 and Arginase-1 Expression in Macrophages.

The RNA world in the 21st century-a systems approach to finding non-coding keys to clinical questions.

The Role of Age, Neutrophil Infiltration and Antibiotics Timing in the Severity of Streptococcus pneumoniae Pneumonia. Insights from a Multi-Level Mathematical Model Approach

The Role of Immune Checkpoint Blockade in Uveal Melanoma

The systems biology of mitochondrial fission and fusion and implications for disease and aging

Third-Kind Encounters in Biomedicine: Immunology Meets Mathematics and Informatics to Become Quantitative and Predictive.

Transcription factor Sox10 regulates oligodendroglial Sox9 levels via microRNAs

Transcriptional Profiling of Ligand Expression in Cell Specific Populations of the Adult Mouse Forebrain That Regulates Neurogenesis.

Transcriptional analysis identifies potential biomarkers and molecular regulators in pneumonia and COPD exacerbation

Tumors as chaotic attractors

Understanding microRNA-mediated gene regulatory networks through mathematical modelling.

Unraveling a tumor type-specific regulatory core underlying E2F1-mediated epithelial-mesenchymal transition to predict receptor protein signatures

Whither systems medicine?