Lista de obras - Peter van der Ley - Dominio Público Uruguay

A Neisserial autotransporter NalP modulating the processing of other autotransporters ⬇️

artículo científico publicado el 1 de noviembre de 2003

A novel secondary acyl chain in the lipopolysaccharide of Bordetella pertussis required for efficient infection of human macrophages

artículo científico publicado en 2007

Acellular pertussis vaccine based on outer membrane vesicles capable of conferring both long-lasting immunity and protection against different strain genotypes

artículo científico publicado en 2014

Agonists of Toll-like receptors 3, 4, 7, and 9 are candidates for use as adjuvants in an outer membrane vaccine against Neisseria meningitidis serogroup B.

artículo científico publicado en 2007

Antigen sparing with adjuvanted inactivated polio vaccine based on Sabin strains

artículo científico publicado en 2013

Biosynthetically engineered lipopolysaccharide as vaccine adjuvant

artículo científico

Bordetella pertussis naturally occurring isolates with altered lipooligosaccharide structure fail to fully mature human dendritic cells

artículo científico publicado en 2014

Coincorporation of LpxL1 and PagL mutant lipopolysaccharides into liposomes with Neisseria meningitidis opacity protein: influence on endotoxic and adjuvant activity

artículo científico publicado en 2010

Conformational analysis of opacity proteins from Neisseria meningitidis

artículo científico publicado en 2002

Construction of Opa-positive and Opa-negative strains of Neisseria meningitidis to evaluate a novel meningococcal vaccine

artículo científico publicado en 2012

Crystal structure and catalytic mechanism of the LPS 3-O-deacylase PagL from Pseudomonas aeruginosa

scientific journal article

Cysteine depletion causes oxidative stress and triggers outer membrane vesicle release by Neisseria meningitidis; implications for vaccine development

artículo científico publicado en 2013

Differential activation of human and mouse Toll-like receptor 4 by the adjuvant candidate LpxL1 of Neisseria meningitidis

artículo científico publicado en 2008

Differential effect of TLR2 and TLR4 on the immune response after immunization with a vaccine against Neisseria meningitidis or Bordetella pertussis

artículo científico publicado en 2010

Dissemination of lipid A deacylases (pagL) among gram-negative bacteria: identification of active-site histidine and serine residues

scientific journal article

Expression of foreign LpxA acyltransferases in Neisseria meningitidis results in modified lipid A with reduced toxicity and retained adjuvant activity

artículo científico publicado en 2002

Expression of the lipopolysaccharide-modifying enzymes PagP and PagL modulates the endotoxic activity of Bordetella pertussis

artículo científico publicado en 2006

Human dendritic cell activation by Neisseria meningitidis: phagocytosis depends on expression of lipooligosaccharide (LOS) by the bacteria and is required for optimal cytokine production

artículo científico publicado en 2004

Human lipoproteins have divergent neutralizing effects on E. coli LPS, N. meningitidis LPS, and complete Gram-negative bacteria

artículo científico publicado en 2004

Identification of a novel lipopolysaccharide core biosynthesis gene cluster in Bordetella pertussis, and influence of core structure and lipid A glucosamine substitution on endotoxic activity

scientific article published on 13 April 2009

Involvement of lipooligosaccharides of Haemophilus influenzae and Neisseria meningitidis in defensin-enhanced bacterial adherence to epithelial cells

artículo científico publicado en 2003

LOS oligosaccharide modification enhances dendritic cell responses to meningococcal native outer membrane vesicles expressing a non-toxic lipid A

artículo científico publicado en 2013

Lipoarabinomannan mannose caps do not affect mycobacterial virulence or the induction of protective immunity in experimental animal models of infection and have minimal impact on in vitro inflammatory responses

artículo científico publicado en 2012

Lipopolysaccharide analogs improve efficacy of acellular pertussis vaccine and reduce type I hypersensitivity in mice

artículo científico publicado en 2007

Lipopolysaccharide engineering in Neisseria meningitidis: structural analysis of different pentaacyl lipid A mutants and comparison of their modified agonist properties

artículo científico publicado en 2014

Llama single-chain antibody that blocks lipopolysaccharide binding and signaling: prospects for therapeutic applications

artículo científico

Mannose binding lectin enhances IL-1beta and IL-10 induction by non-lipopolysaccharide (LPS) components of Neisseria meningitidis

artículo científico publicado en 2004

Mapping the binding domains on meningococcal Opa proteins for CEACAM1 and CEA receptors ⬇️

artículo científico publicado el 1 de noviembre de 2003

Meningitis caused by a lipopolysaccharide deficient Neisseria meningitidis

artículo científico publicado en 2014

Meningococcal Outer Membrane Vesicle Composition-Dependent Activation of the Innate Immune Response

scientific article published on August 2016

Modulating endotoxin activity by combinatorial bioengineering of meningococcal lipopolysaccharide.

artículo científico publicado en 2016

Modulation of the CD4(+) T cell response after acellular pertussis vaccination in the presence of TLR4 ligation

artículo científico publicado en 2015

Naturally occurring lipid A mutants in neisseria meningitidis from patients with invasive meningococcal disease are associated with reduced coagulopathy

artículo científico publicado en 2009

Opa+ and Opa- isolates of Neisseria meningitidis and Neisseria gonorrhoeae induce sustained proliferative responses in human CD4+ T cells

artículo científico publicado en 2009

Outer membrane vesicles as platform vaccine technology

artículo científico publicado en 2015

Phase variation of Opa proteins of Neisseria meningitidis and the effects of bacterial transformation

artículo científico publicado en 2016

Prevalence and clinical course in invasive infections with meningococcal endotoxin variants

artículo científico publicado en 2012

Relative Immunogenicity of PorA Subtypes in a Multivalent Neisseria meningitidis Vaccine Is Not Dependent on Presentation Form ⬇️

artículo científico publicado el 1 de noviembre de 2003

Supplementation of whole-cell pertussis vaccines with lipopolysaccharide analogs: modification of vaccine-induced immune responses

artículo científico publicado en 2007

Surface display of a borrelial lipoprotein on meningococcal outer membrane vesicles

artículo científico publicado en 2016

TLR4-dependent adjuvant activity of Neisseria meningitidis lipid A

artículo científico publicado en 2007

Teasing apart structural determinants of 'toxicity' and 'adjuvanticity': implications for meningococcal vaccine development

artículo científico publicado en 2004

Th17-mediated cross protection against pneumococcal carriage by vaccination with a variable antigen

artículo científico publicado en 2017

The Omp85 protein of Neisseria meningitidis is required for lipid export to the outer membrane

artículo científico publicado en 2003

The structure of Neisseria meningitidis lipid A determines outcome in experimental meningococcal disease

artículo científico publicado en 2010

Working mechanism of immunoglobulin A1 (IgA1) protease: cleavage of IgA1 antibody to Neisseria meningitidis PorA requires de novo synthesis of IgA1 Protease

artículo científico publicado en 2005

Lista de obras de Peter van der Ley

A Neisserial autotransporter NalP modulating the processing of other autotransporters ⬇️

A novel secondary acyl chain in the lipopolysaccharide of Bordetella pertussis required for efficient infection of human macrophages

Acellular pertussis vaccine based on outer membrane vesicles capable of conferring both long-lasting immunity and protection against different strain genotypes

Agonists of Toll-like receptors 3, 4, 7, and 9 are candidates for use as adjuvants in an outer membrane vaccine against Neisseria meningitidis serogroup B.

Antigen sparing with adjuvanted inactivated polio vaccine based on Sabin strains

Biosynthetically engineered lipopolysaccharide as vaccine adjuvant

Bordetella pertussis naturally occurring isolates with altered lipooligosaccharide structure fail to fully mature human dendritic cells

Coincorporation of LpxL1 and PagL mutant lipopolysaccharides into liposomes with Neisseria meningitidis opacity protein: influence on endotoxic and adjuvant activity

Conformational analysis of opacity proteins from Neisseria meningitidis

Construction of Opa-positive and Opa-negative strains of Neisseria meningitidis to evaluate a novel meningococcal vaccine

Crystal structure and catalytic mechanism of the LPS 3-O-deacylase PagL from Pseudomonas aeruginosa

Cysteine depletion causes oxidative stress and triggers outer membrane vesicle release by Neisseria meningitidis; implications for vaccine development

Differential activation of human and mouse Toll-like receptor 4 by the adjuvant candidate LpxL1 of Neisseria meningitidis

Differential effect of TLR2 and TLR4 on the immune response after immunization with a vaccine against Neisseria meningitidis or Bordetella pertussis

Dissemination of lipid A deacylases (pagL) among gram-negative bacteria: identification of active-site histidine and serine residues

Expression of foreign LpxA acyltransferases in Neisseria meningitidis results in modified lipid A with reduced toxicity and retained adjuvant activity

Expression of the lipopolysaccharide-modifying enzymes PagP and PagL modulates the endotoxic activity of Bordetella pertussis

Human dendritic cell activation by Neisseria meningitidis: phagocytosis depends on expression of lipooligosaccharide (LOS) by the bacteria and is required for optimal cytokine production

Human lipoproteins have divergent neutralizing effects on E. coli LPS, N. meningitidis LPS, and complete Gram-negative bacteria

Identification of a novel lipopolysaccharide core biosynthesis gene cluster in Bordetella pertussis, and influence of core structure and lipid A glucosamine substitution on endotoxic activity

Involvement of lipooligosaccharides of Haemophilus influenzae and Neisseria meningitidis in defensin-enhanced bacterial adherence to epithelial cells

LOS oligosaccharide modification enhances dendritic cell responses to meningococcal native outer membrane vesicles expressing a non-toxic lipid A

Lipoarabinomannan mannose caps do not affect mycobacterial virulence or the induction of protective immunity in experimental animal models of infection and have minimal impact on in vitro inflammatory responses

Lipopolysaccharide analogs improve efficacy of acellular pertussis vaccine and reduce type I hypersensitivity in mice

Lipopolysaccharide engineering in Neisseria meningitidis: structural analysis of different pentaacyl lipid A mutants and comparison of their modified agonist properties

Llama single-chain antibody that blocks lipopolysaccharide binding and signaling: prospects for therapeutic applications

Mannose binding lectin enhances IL-1beta and IL-10 induction by non-lipopolysaccharide (LPS) components of Neisseria meningitidis

Mapping the binding domains on meningococcal Opa proteins for CEACAM1 and CEA receptors ⬇️

Meningitis caused by a lipopolysaccharide deficient Neisseria meningitidis

Meningococcal Outer Membrane Vesicle Composition-Dependent Activation of the Innate Immune Response

Modulating endotoxin activity by combinatorial bioengineering of meningococcal lipopolysaccharide.

Modulation of the CD4(+) T cell response after acellular pertussis vaccination in the presence of TLR4 ligation

Naturally occurring lipid A mutants in neisseria meningitidis from patients with invasive meningococcal disease are associated with reduced coagulopathy

Opa+ and Opa- isolates of Neisseria meningitidis and Neisseria gonorrhoeae induce sustained proliferative responses in human CD4+ T cells

Outer membrane vesicles as platform vaccine technology

Phase variation of Opa proteins of Neisseria meningitidis and the effects of bacterial transformation

Prevalence and clinical course in invasive infections with meningococcal endotoxin variants

Relative Immunogenicity of PorA Subtypes in a Multivalent Neisseria meningitidis Vaccine Is Not Dependent on Presentation Form ⬇️

Supplementation of whole-cell pertussis vaccines with lipopolysaccharide analogs: modification of vaccine-induced immune responses

Surface display of a borrelial lipoprotein on meningococcal outer membrane vesicles

TLR4-dependent adjuvant activity of Neisseria meningitidis lipid A

Teasing apart structural determinants of 'toxicity' and 'adjuvanticity': implications for meningococcal vaccine development

Th17-mediated cross protection against pneumococcal carriage by vaccination with a variable antigen

The Omp85 protein of Neisseria meningitidis is required for lipid export to the outer membrane

The structure of Neisseria meningitidis lipid A determines outcome in experimental meningococcal disease

Working mechanism of immunoglobulin A1 (IgA1) protease: cleavage of IgA1 antibody to Neisseria meningitidis PorA requires de novo synthesis of IgA1 Protease