Lista de obras - Luis Javier Santin Nuñez

1-Oleoyl lysophosphatidic acid: a new mediator of emotional behavior in rats.

artículo científico publicado en 2014

5-HT1A receptor activation before acute stress counteracted the induced long-term behavioral effects.

artículo científico publicado en 2004

5-HT1A receptor activation counteracted the effect of acute immobilization of noradrenergic neurons in the rat locus coeruleus

artículo científico publicado en 2007

5-HT1A receptor activation counteracts c-Fos immunoreactivity induced in serotonin neurons of the raphe nuclei after immobilization stress in the male rat.

artículo científico publicado en 2006

A Novel Integrative Mechanism in Anxiolytic Behavior Induced by Galanin 2/Neuropeptide Y Y1 Receptor Interactions on Medial Paracapsular Intercalated Amygdala in Rats

artículo científico publicado en 2018

A place for the hippocampus in the cocaine addiction circuit: Potential roles for adult hippocampal neurogenesis

artículo científico publicado en 2016

A role for galanin N-terminal fragment (1-15) in anxiety- and depression-related behaviors in rats

artículo científico publicado en 2014

Absence of LPA1 signaling results in defective cortical development.

artículo científico publicado en 2007

Age-related changes of the nucleolar organizer regions without neuron loss in medial mamillary bodies (hypothalamus) in old rats

artículo científico publicado en 1999

Aggravation of chronic stress effects on hippocampal neurogenesis and spatial memory in LPA₁ receptor knockout mice

artículo científico publicado en 2011

Alcohol-induced cognitive deficits are associated with decreased circulating levels of the neurotrophin BDNF in humans and rats

scientific article published on 12 September 2018

Anatomical location of LPA1 activation and LPA phospholipid precursors in rodent and human brain.

artículo científico publicado en 2015

Attenuation of cocaine-induced conditioned locomotion is associated with altered expression of hippocampal glutamate receptors in mice lacking LPA1 receptors

artículo científico publicado en 2011

Behavioral phenotype of maLPA1-null mice: increased anxiety-like behavior and spatial memory deficits

artículo científico publicado en 2009

Behaviour laterality in male rats: influence of practice and stress

artículo científico publicado en 1996

Both genetic deletion and pharmacological blockade of lysophosphatidic acid LPA1 receptor results in increased alcohol consumption.

artículo científico publicado en 2015

Central administration of galanin N-terminal fragment 1-15 decreases the voluntary alcohol intake in rats.

artículo científico publicado en 2017

Changes in the Nucleolar Organizer Regions in the Tuberomammillar Region after Dehydration ⬇️

artículo científico publicado el 1 de octubre de 1997

Chronic immobilization in the malpar1 knockout mice increases oxidative stress in the hippocampus.

artículo científico publicado en 2012

Cocaine-conditioned place preference is predicted by previous anxiety-like behavior and is related to an increased number of neurons in the basolateral amygdala

artículo científico publicado en 2015

Correction: Aggravation of Chronic Stress Effects on Hippocampal Neurogenesis and Spatial Memory in LPA1 Receptor Knockout Mice.

artículo científico publicado en 2011

Deletion of lysophosphatidic acid receptor LPA1 reduces neurogenesis in the mouse dentate gyrus

artículo científico publicado en 2008

Dopamine D4 receptor stimulation prevents nigrostriatal dopamine pathway activation by morphine: relevance for drug addiction

artículo científico publicado en 2016

Effects of ageing on allocentric and egocentric spatial strategies in the Wistar rat.

artículo científico publicado en 2001

Effects of chronic alcohol consumption on spatial reference and working memory tasks

artículo científico publicado en 2000

Effects of genetic deletion versus pharmacological blockade of the LPA receptor on depression-like behaviour and related brain functional activity

scientific article published on 10 September 2018

Effects of histamine precursor and (R)-Î±-methylhistamine on the avoidance response in rats ⬇️

artículo científico publicado el 15 de octubre de 2001

Effects of mammillary body lesions on spatial reference and working memory tasks

artículo científico publicado en 1999

Effects of medial prefrontal cortex lesions on anxiety-like behaviour in restrained and non-restrained rats

artículo científico publicado en 2009

Environmental enrichment as a therapeutic avenue for anxiety in aged Wistar rats: Effect on cat odor exposition and GABAergic interneurons.

artículo científico publicado en 2016

Ethanol- and diazepam-induced cytochrome oxidase activity in mammillary bodies

artículo científico publicado en 1996

Exploratory, anxiety and spatial memory impairments are dissociated in mice lacking the LPA1 receptor

artículo científico publicado en 2010

Fear extinction and acute stress reactivity reveal a role of LPA(1) receptor in regulating emotional-like behaviors.

artículo científico publicado en 2013

Functional networks involved in spatial learning strategies in middle-aged rats

artículo científico publicado en 2012

Functional sex differences in the accessory olfactory bulb of the rat

artículo científico publicado en 2000

Galanin (1-15) enhancement of the behavioral effects of Fluoxetine in the forced swimming test gives a new therapeutic strategy against depression.

artículo científico publicado en 2017

Galanin (1-15) enhances the antidepressant effects of the 5-HT1A receptor agonist 8-OH-DPAT: involvement of the raphe-hippocampal 5-HT neuron system

artículo científico publicado en 2016

Galanin (1-15)-fluoxetine interaction in the novel object recognition test. Involvement of 5-HT1A receptors in the prefrontal cortex of the rats

artículo científico publicado en 2019

Galanin receptor 2-neuropeptide Y Y1 receptor interactions in the amygdala lead to increased anxiolytic actions.

artículo científico publicado en 2014

Galanin receptor 2-neuropeptide Y Y1 receptor interactions in the dentate gyrus are related with antidepressant-like effects.

artículo científico publicado en 2015

Galanin receptor/Neuropeptide Y receptor interactions in the dorsal raphe nucleus of the rat

artículo científico publicado en 2011

Higher Impulsivity As a Distinctive Trait of Severe Cocaine Addiction among Individuals Treated for Cocaine or Alcohol Use Disorders

artículo científico publicado en 2018

Highlighting the Role of Cognitive and Brain Reserve in the Substance use Disorder Field

scientific article published on 01 January 2019

Hippocampal c-Fos activation in normal and LPA₁-null mice after two object recognition tasks with different memory demands.

artículo científico publicado en 2012

Hyperactivity induced by the dopamine D2/D3 receptor agonist quinpirole is attenuated by inhibitors of endocannabinoid degradation in mice

artículo científico publicado en 2012

IGF-II promotes neuroprotection and neuroplasticity recovery in a long-lasting model of oxidative damage induced by glucocorticoids

artículo científico publicado en 2017

Imbalance of Endocannabinoid/Lysophosphatidylinositol Receptors Marks the Severity of Alzheimer's Disease in a Preclinical Model: A Therapeutic Opportunity

artículo científico publicado en 2020

Improvement of spatial memory by (R)-alpha-methylhistamine, a histamine H(3)-receptor agonist, on the Morris water-maze in rat.

artículo científico publicado en 2002

Involvement of IGF-II receptors in the antioxidant and neuroprotective effects of IGF-II on adult cortical neuronal cultures.

artículo científico publicado en 2014

Long-lasting memory deficits in mice withdrawn from cocaine are concomitant with neuroadaptations in hippocampal basal activity, GABAergic interneurons and adult neurogenesis

scientific article published on 30 January 2017

Loss of lysophosphatidic acid receptor LPA1 alters oligodendrocyte differentiation and myelination in the mouse cerebral cortex.

artículo científico publicado en 2014

Lysophosphatidic acid-induced increase in adult hippocampal neurogenesis facilitates the forgetting of cocaine-contextual memory.

artículo científico publicado en 2018

Moderate and severe perinatal asphyxia induces differential effects on cocaine sensitization in adult rats

artículo científico publicado en 2013

Neuroplastic and cognitive impairment in substance use disorders: a therapeutic potential of cognitive stimulation

scientific article published on 24 November 2018

Neuroplasticity and Healthy Lifestyle: How Can We Understand This Relationship?

artículo científico publicado en 2017

Non-effects of mammillary body lesions on spontaneous alternation: pre and postoperative study

artículo científico publicado en 1999

Palmitoylethanolamide attenuates cocaine-induced behavioral sensitization and conditioned place preference in mice

artículo científico publicado en 2018

Pharmacological reduction of adult hippocampal neurogenesis modifies functional brain circuits in mice exposed to a cocaine conditioned place preference paradigm

artículo científico publicado en 2015

Plasma concentrations of BDNF and IGF-1 in abstinent cocaine users with high prevalence of substance use disorders: relationship to psychiatric comorbidity

artículo científico publicado en 2015

Plasma redox status is impaired in the portacaval shunted rat--the risk of the reduced antioxidant ability.

artículo científico publicado en 2008

Portacaval shunt control animals: physiological consequences derived from the sham operation

scientific article published on 01 July 1997

Portal hypertension in 18-month-old rats: memory deficits and brain metabolic activity

artículo científico publicado en 2010

Reduced wheel running and blunted effects of voluntary exercise in LPA1-null mice: the importance of assessing the amount of running in transgenic mice studies

artículo científico publicado en 2013

Remote memory of drug experiences coexists with cognitive decline and abnormal adult neurogenesis in an animal model of cocaine-altered cognition

artículo científico publicado en 2020

Reversible changes in hippocampal CA1 synapses associated with water maze training in rats

artículo científico publicado en 2006

Role of Lysophosphatidic Acid (LPA) in Behavioral Processes: Implications for Psychiatric Disorders

artículo científico publicado en 2013

Role of the galanin N-terminal fragment (1-15) in anhedonia: Involvement of the dopaminergic mesolimbic system

artículo científico publicado en 2019

Serotonin is the main tryptophan metabolite associated with psychiatric comorbidity in abstinent cocaine-addicted patients

scientific article published on 14 November 2019

Spatial learning and the hippocampus

artículo científico publicado en 2000

Supramammillary and adjacent nuclei lesions impair spatial working memory and induce anxiolitic-like behavior

artículo científico publicado en 2005

Systemic blockade of LPA1/3 lysophosphatidic acid receptors by ki16425 modulates the effects of ethanol on the brain and behavior.

artículo científico publicado en 2018

Temporary inactivation of the supramammillary area impairs spatial working memory and spatial reference memory retrieval

artículo científico publicado en 2008

The impact of cocaine on adult hippocampal neurogenesis: Potential neurobiological mechanisms and contributions to maladaptive cognition in cocaine addiction disorder

artículo científico

The neuropeptides Galanin and Galanin(1-15) in depression-like behaviours

artículo científico publicado en 2017

The presence of a social stimulus reduces cocaine-seeking in a place preference conditioning paradigm

scientific article published on 23 September 2019

Training memory without aversion: Appetitive hole-board spatial learning increases adult hippocampal neurogenesis

artículo científico publicado en 2018

Unbiased estimation of the total number of nervous cells and volume of medial mammillary nucleus in humans

artículo científico publicado en 1999

Voluntary exercise followed by chronic stress strikingly increases mature adult-born hippocampal neurons and prevents stress-induced deficits in 'what-when-where' memory

artículo científico publicado en 2013

When is adult hippocampal neurogenesis necessary for learning? evidence from animal research.

scientific article published on 13 May 2011

Where to place the rewards? Exploration bias in mice influences performance in the classic hole-board spatial memory test

artículo científico publicado en 2019

c-Fos expression in supramammillary and medial mammillary nuclei following spatial reference and working memory tasks

artículo científico publicado en 2003

maLPA1-null mice as an endophenotype of anxious depression

artículo científico publicado en 2017

Lista de obras de Luis Javier Santin Nuñez

1-Oleoyl lysophosphatidic acid: a new mediator of emotional behavior in rats.

5-HT1A receptor activation before acute stress counteracted the induced long-term behavioral effects.

5-HT1A receptor activation counteracted the effect of acute immobilization of noradrenergic neurons in the rat locus coeruleus

5-HT1A receptor activation counteracts c-Fos immunoreactivity induced in serotonin neurons of the raphe nuclei after immobilization stress in the male rat.

A Novel Integrative Mechanism in Anxiolytic Behavior Induced by Galanin 2/Neuropeptide Y Y1 Receptor Interactions on Medial Paracapsular Intercalated Amygdala in Rats

A place for the hippocampus in the cocaine addiction circuit: Potential roles for adult hippocampal neurogenesis

A role for galanin N-terminal fragment (1-15) in anxiety- and depression-related behaviors in rats

Absence of LPA1 signaling results in defective cortical development.

Age-related changes of the nucleolar organizer regions without neuron loss in medial mamillary bodies (hypothalamus) in old rats

Aggravation of chronic stress effects on hippocampal neurogenesis and spatial memory in LPA₁ receptor knockout mice

Alcohol-induced cognitive deficits are associated with decreased circulating levels of the neurotrophin BDNF in humans and rats

Anatomical location of LPA1 activation and LPA phospholipid precursors in rodent and human brain.

Attenuation of cocaine-induced conditioned locomotion is associated with altered expression of hippocampal glutamate receptors in mice lacking LPA1 receptors

Behavioral phenotype of maLPA1-null mice: increased anxiety-like behavior and spatial memory deficits

Behaviour laterality in male rats: influence of practice and stress

Both genetic deletion and pharmacological blockade of lysophosphatidic acid LPA1 receptor results in increased alcohol consumption.

Central administration of galanin N-terminal fragment 1-15 decreases the voluntary alcohol intake in rats.

Changes in the Nucleolar Organizer Regions in the Tuberomammillar Region after Dehydration ⬇️

Chronic immobilization in the malpar1 knockout mice increases oxidative stress in the hippocampus.

Cocaine-conditioned place preference is predicted by previous anxiety-like behavior and is related to an increased number of neurons in the basolateral amygdala

Correction: Aggravation of Chronic Stress Effects on Hippocampal Neurogenesis and Spatial Memory in LPA1 Receptor Knockout Mice.

Deletion of lysophosphatidic acid receptor LPA1 reduces neurogenesis in the mouse dentate gyrus

Dopamine D4 receptor stimulation prevents nigrostriatal dopamine pathway activation by morphine: relevance for drug addiction

Effects of ageing on allocentric and egocentric spatial strategies in the Wistar rat.

Effects of chronic alcohol consumption on spatial reference and working memory tasks

Effects of genetic deletion versus pharmacological blockade of the LPA receptor on depression-like behaviour and related brain functional activity

Effects of histamine precursor and (R)-Î±-methylhistamine on the avoidance response in rats ⬇️

Effects of mammillary body lesions on spatial reference and working memory tasks

Effects of medial prefrontal cortex lesions on anxiety-like behaviour in restrained and non-restrained rats

Environmental enrichment as a therapeutic avenue for anxiety in aged Wistar rats: Effect on cat odor exposition and GABAergic interneurons.

Ethanol- and diazepam-induced cytochrome oxidase activity in mammillary bodies

Exploratory, anxiety and spatial memory impairments are dissociated in mice lacking the LPA1 receptor

Fear extinction and acute stress reactivity reveal a role of LPA(1) receptor in regulating emotional-like behaviors.

Functional networks involved in spatial learning strategies in middle-aged rats

Functional sex differences in the accessory olfactory bulb of the rat

Galanin (1-15) enhancement of the behavioral effects of Fluoxetine in the forced swimming test gives a new therapeutic strategy against depression.

Galanin (1-15) enhances the antidepressant effects of the 5-HT1A receptor agonist 8-OH-DPAT: involvement of the raphe-hippocampal 5-HT neuron system

Galanin (1-15)-fluoxetine interaction in the novel object recognition test. Involvement of 5-HT1A receptors in the prefrontal cortex of the rats

Galanin receptor 2-neuropeptide Y Y1 receptor interactions in the amygdala lead to increased anxiolytic actions.

Galanin receptor 2-neuropeptide Y Y1 receptor interactions in the dentate gyrus are related with antidepressant-like effects.

Galanin receptor/Neuropeptide Y receptor interactions in the dorsal raphe nucleus of the rat

Higher Impulsivity As a Distinctive Trait of Severe Cocaine Addiction among Individuals Treated for Cocaine or Alcohol Use Disorders

Highlighting the Role of Cognitive and Brain Reserve in the Substance use Disorder Field

Hippocampal c-Fos activation in normal and LPA₁-null mice after two object recognition tasks with different memory demands.

Hyperactivity induced by the dopamine D2/D3 receptor agonist quinpirole is attenuated by inhibitors of endocannabinoid degradation in mice

IGF-II promotes neuroprotection and neuroplasticity recovery in a long-lasting model of oxidative damage induced by glucocorticoids

Imbalance of Endocannabinoid/Lysophosphatidylinositol Receptors Marks the Severity of Alzheimer's Disease in a Preclinical Model: A Therapeutic Opportunity

Improvement of spatial memory by (R)-alpha-methylhistamine, a histamine H(3)-receptor agonist, on the Morris water-maze in rat.

Involvement of IGF-II receptors in the antioxidant and neuroprotective effects of IGF-II on adult cortical neuronal cultures.

Long-lasting memory deficits in mice withdrawn from cocaine are concomitant with neuroadaptations in hippocampal basal activity, GABAergic interneurons and adult neurogenesis

Loss of lysophosphatidic acid receptor LPA1 alters oligodendrocyte differentiation and myelination in the mouse cerebral cortex.

Lysophosphatidic acid-induced increase in adult hippocampal neurogenesis facilitates the forgetting of cocaine-contextual memory.

Moderate and severe perinatal asphyxia induces differential effects on cocaine sensitization in adult rats

Neuroplastic and cognitive impairment in substance use disorders: a therapeutic potential of cognitive stimulation

Neuroplasticity and Healthy Lifestyle: How Can We Understand This Relationship?

Non-effects of mammillary body lesions on spontaneous alternation: pre and postoperative study

Palmitoylethanolamide attenuates cocaine-induced behavioral sensitization and conditioned place preference in mice

Pharmacological reduction of adult hippocampal neurogenesis modifies functional brain circuits in mice exposed to a cocaine conditioned place preference paradigm

Plasma concentrations of BDNF and IGF-1 in abstinent cocaine users with high prevalence of substance use disorders: relationship to psychiatric comorbidity

Plasma redox status is impaired in the portacaval shunted rat--the risk of the reduced antioxidant ability.

Portacaval shunt control animals: physiological consequences derived from the sham operation

Portal hypertension in 18-month-old rats: memory deficits and brain metabolic activity

Reduced wheel running and blunted effects of voluntary exercise in LPA1-null mice: the importance of assessing the amount of running in transgenic mice studies

Remote memory of drug experiences coexists with cognitive decline and abnormal adult neurogenesis in an animal model of cocaine-altered cognition

Reversible changes in hippocampal CA1 synapses associated with water maze training in rats

Role of Lysophosphatidic Acid (LPA) in Behavioral Processes: Implications for Psychiatric Disorders

Role of the galanin N-terminal fragment (1-15) in anhedonia: Involvement of the dopaminergic mesolimbic system

Serotonin is the main tryptophan metabolite associated with psychiatric comorbidity in abstinent cocaine-addicted patients

Spatial learning and the hippocampus

Supramammillary and adjacent nuclei lesions impair spatial working memory and induce anxiolitic-like behavior

Systemic blockade of LPA1/3 lysophosphatidic acid receptors by ki16425 modulates the effects of ethanol on the brain and behavior.

Temporary inactivation of the supramammillary area impairs spatial working memory and spatial reference memory retrieval

The impact of cocaine on adult hippocampal neurogenesis: Potential neurobiological mechanisms and contributions to maladaptive cognition in cocaine addiction disorder

The neuropeptides Galanin and Galanin(1-15) in depression-like behaviours

The presence of a social stimulus reduces cocaine-seeking in a place preference conditioning paradigm

Training memory without aversion: Appetitive hole-board spatial learning increases adult hippocampal neurogenesis

Unbiased estimation of the total number of nervous cells and volume of medial mammillary nucleus in humans

Voluntary exercise followed by chronic stress strikingly increases mature adult-born hippocampal neurons and prevents stress-induced deficits in 'what-when-where' memory

When is adult hippocampal neurogenesis necessary for learning? evidence from animal research.