Lista de obras - Clemens O. Hanemann - Dominio Público Uruguay

A functional association between merlin and HEI10, a cell cycle regulator.

artículo científico publicado en 2006

A multicentre evaluation of oropharyngeal secretion management practices in amyotrophic lateral sclerosis

artículo científico publicado en 2016

A novel nonsense mutation in the ABC1 gene causes a severe syringomyelia-like phenotype of Tangier disease

artículo científico publicado en 2003

ALS/MND meeting of the European ALS/MND group Reisensburg Castle 30 January – 1 February 2003

scientific article published on 01 June 2003

Achieving consensus for clinical trials: the REiNS International Collaboration.

artículo científico publicado en 2013

Acquired rippling muscle disease in association with myasthenia gravis

artículo científico publicado en 2010

Actin-rich protrusions and nonlocalized GTPase activation in Merlin-deficient schwannomas

artículo científico publicado en 2007

Activation of ERK, AKT and JNK signalling pathways in human schwannomas in situ.

artículo científico publicado en 2009

Activation of multiple growth factor signalling pathways is frequent in meningiomas

artículo científico publicado en 2015

An Essential Role for the Tumor-Suppressor Merlin in Regulating Fatty Acid Synthesis

artículo científico publicado en 2017

Artesunate induces necrotic cell death in schwannoma cells.

artículo científico publicado en 2014

Axl/Gas6/NFκB signalling in schwannoma pathological proliferation, adhesion and survival.

artículo científico publicado en 2013

Axon damage in CMT due to mutation in myelin protein P0

artículo científico publicado en 2001

Balo's concentric sclerosis followed by MRI and positron emission tomography

artículo científico publicado en 1993

Benign symmetric lipomatosis with axonal neuropathy and abnormalities in specific mitochondrial tRNA regions

artículo científico publicado en 2006

CTF meeting 2012: Translation of the basic understanding of the biology and genetics of NF1, NF2, and schwannomatosis toward the development of effective therapies.

artículo científico publicado en 2014

Cannabinoid Receptor and N‐acyl Phosphatidylethanolamine Phospholipase D—Evidence for Altered Expression in Multiple Sclerosis ⬇️

artículo científico publicado el 22 de febrero de 2011

Cellular contaminants of adeno-associated virus vector stocks can enhance transduction.

artículo científico publicado en 1999

Cellular prion protein (PrP(C)) in the development of Merlin-deficient tumours

artículo científico publicado en 2017

Characterization of basal ganglia dysfunction in Leber 'plus' disease

artículo científico publicado en 1996

Combined Inhibition of NEDD8-Activating Enzyme and mTOR Suppresses NF2 Loss-Driven Tumorigenesis.

artículo científico publicado en 2017

Complicated hereditary spastic paraplegia with thin corpus callosum: Variation of phenotypic expression over time

article

Conclusions and future directions for the REiNS International Collaboration.

artículo científico publicado en 2013

Congenital axonal neuropathy caused by deletions in the spinal muscular atrophy region

artículo científico publicado en 1997

Consensus recommendations for current treatments and accelerating clinical trials for patients with neurofibromatosis type 2

article

Constitutive activation of the EGFR-STAT1 axis increases proliferation of meningioma tumor cells

artículo científico publicado en 2020

Delta-9-tetrahydrocannabinol protects against MPP+ toxicity in SH-SY5Y cells by restoring proteins involved in mitochondrial biogenesis

artículo científico publicado en 2016

DiPALS: Diaphragm Pacing in patients with Amyotrophic Lateral Sclerosis - a randomised controlled trial.

artículo científico publicado en 2016

Differential gene expression between human schwannoma and control Schwann cells.

artículo científico publicado en 2006

Enhanced proliferation and potassium conductance of Schwann cells isolated from NF2 schwannomas can be reduced by quinidine

scientific article published on 01 August 2000

Expression of c-Jun and Sox-2 in human schwannomas and traumatic neuromas.

artículo científico publicado en 2013

Expression of decorin mRNA in the nervous system of rat.

artículo científico publicado en 1993

FKRP (826C>A) frequently causes limb-girdle muscular dystrophy in German patients

artículo científico publicado en 2004

Fludeoxyglucose F 18 positron emission tomography and computed tomography of a giant retroperitoneal schwannoma occurring in a patient with neurofibromatosis type 2.

artículo científico publicado en 2005

Global Proteome and Phospho-proteome Analysis of Merlin-deficient Meningioma and Schwannoma Identifies PDLIM2 as a Novel Therapeutic Target.

artículo científico publicado en 2017

Hereditary demyelinating neuropathies: from gene to disease.

artículo científico publicado en 2001

Hereditary motor neuropathies and motor neuron diseases: which is which.

artículo científico publicado en 2002

Heterozygous R1101K mutation of the DCTN1 gene in a family with ALS and FTD.

artículo científico publicado en 2005

Impaired intercellular adhesion and immature adherens junctions in merlin-deficient human primary schwannoma cells

artículo científico publicado en 2008

Improved culture methods to expand Schwann cells with altered growth behaviour from CMT1A patients

scientific article published on 01 June 1998

Insulin-like growth factor-binding protein-1 (IGFBP-1) regulates human schwannoma proliferation, adhesion and survival.

artículo científico publicado en 2011

Integration and Comparison of Transcriptomic and Proteomic Data for Meningioma

artículo científico publicado en 2020

Isolation and characterization of Schwann cells from neurofibromatosis type 2 patients

artículo científico publicado en 1998

Lack of immune responses to immediate or delayed implanted allogeneic and xenogeneic Schwann cell suspensions ⬇️

artículo científico publicado el 1 de noviembre de 1997

Laryngospasm: an underdiagnosed symptom of X-linked spinobulbar muscular atrophy

artículo científico publicado en 2005

Long-term culture and characterization of human neurofibroma-derived Schwann cells

scientific article published on 01 September 2000

Longitudinal evaluation of quality of life in 288 patients with neurofibromatosis 2.

artículo científico publicado en 2014

Low affinity NGF receptor expression in CMT1A nerve biopsies of different disease stages

artículo científico publicado en 1996

MR-pathologic comparison of the upper spinal cord in different motor neuron diseases

artículo científico publicado en 2005

Magic but treatable? Tumours due to loss of merlin.

artículo científico publicado en 2007

Management of sialorrhoea in motor neuron disease: a survey of current UK practice.

artículo científico

Measuring quality of life in ALS/MND: validation of the WHOQOL-BREF

artículo científico publicado en 2020

Medulloblastoma in a patient with the PTPN11 p.Thr468Met mutation.

artículo científico publicado en 2013

Merlin isoform 2 in neurofibromatosis type 2-associated polyneuropathy.

artículo científico publicado en 2013

Merlin-deficient human tumors show loss of contact inhibition and activation of Wnt/β-catenin signaling linked to the PDGFR/Src and Rac/PAK pathways

artículo científico publicado en 2011

Muscle injury in Guillain-Barré syndrome: a case report

artículo científico publicado en 1999

Mutation-dependent alteration in cellular distribution of peripheral myelin protein 22 in nerve biopsies from Charcot-Marie-Tooth type 1A

scientific article published on 01 May 2000

Neurofibromatosis 2011: a report of the Children's Tumor Foundation annual meeting.

artículo científico publicado en 2011

Neurofibromatosis type 1 with involvement of the enteric nerves.

artículo científico publicado en 2007

Neuroligand-mediated calcium signaling in cultured human schwannoma cells

artículo científico publicado en 1999

News on the genetics, epidemiology, medical care and translational research of Schwannomas

artículo científico publicado en 2006

Nilotinib alone or in combination with selumetinib is a drug candidate for neurofibromatosis type 2.

artículo científico publicado en 2011

P06.02ACTIVATION OF MULTIPLE GROWTH FACTOR SIGNALLING PATHWAYS IS FREQUENT IN MENINGIOMAS.

artículo científico publicado en 2014

PAK kinase regulates Rac GTPase and is a potential target in human schwannomas

artículo científico publicado en 2009

PMP22 expression in CMT1a neuropathy

artículo científico publicado en 1995

PO76GROWTH FACTOR SIGNALLING PATHWAYS IN MENINGIOMAS IS COMMON AND PARTLY DEPENDS ON SUBTYPE ALLOWING FOR STRATIFICATION.

artículo científico publicado en 2015

Pathogenesis of Charcot-Marie-Tooth 1A (CMT1A) neuropathy

artículo científico publicado en 1998

Pathological adhesion of primary human schwannoma cells is dependent on altered expression of integrins.

artículo científico publicado en 2003

Peripheral myelin protein-22 expression in Charcot-Marie-Tooth disease type 1a sural nerve biopsies

scientific article published on 01 April 1994

Phase 0 trial investigating the intratumoural concentration and activity of sorafenib in neurofibromatosis type 2

scientific article published on 04 February 2019

Point mutations of the p150 subunit of dynactin (DCTN1) gene in ALS.

artículo científico publicado en 2004

Recent developments in neurofibromatoses and RASopathies: management, diagnosis and current and future therapeutic avenues.

artículo científico publicado en 2014

Recurrent hematomas following craniotomy for traumatic intracranial mass

scientific article published on 01 January 1990

Reduced apoptosis rates in human schwannomas.

artículo científico publicado en 2005

Schwann cell differentiation in Charcot-Marie-Tooth disease type 1A (CMT1A): normal number of myelinating Schwann cells in young CMT1A patients and neural cell adhesion molecule expression in onion bulbs

artículo científico publicado en 1997

Schwannomas and their pathogenesis

artículo científico

Secondary axon atrophy and neurological dysfunction in demyelinating neuropathies.

artículo científico publicado en 2002

Signal therapy of NF1-deficient tumor xenograft in mice by the anti-PAK1 drug FK228.

artículo científico publicado en 2005

Spinal neurofibromatosis without café-au-lait macules in two families with null mutations of the NF1 gene.

artículo científico publicado en 2001

Targeting ERK1/2 activation and proliferation in human primary schwannoma cells with MEK1/2 inhibitor AZD6244.

artículo científico publicado en 2009

Tetracycline-inducible transgene expression mediated by a single AAV vector.

artículo científico publicado en 2003

The Potential of MLN3651 in Combination with Selumetinib as a Treatment for Merlin-Deficient Meningioma

artículo científico publicado en 2020

The epidemiology of motor neurone disease in two counties in the southwest of England.

artículo científico publicado en 2010

The p53/mouse double minute 2 homolog complex deregulation in merlin-deficient tumours

artículo científico publicado en 2014

The peripheral myelin protein gene PMP-22 is contained within the Charcot-Marie-Tooth disease type 1A duplication

artículo científico publicado el 1 de junio de 1992

The role of insulin-like growth factors signaling in merlin-deficient human schwannomas.

artículo científico publicado en 2012

The scaffold protein KSR1, a novel therapeutic target for the treatment of Merlin-deficient tumors

artículo científico publicado en 2015

The tumor suppressor merlin controls growth in its open state, and phosphorylation converts it to a less-active more-closed state.

artículo científico publicado en 2012

Transduction of wild-type merlin into human schwannoma cells decreases schwannoma cell growth and induces apoptosis

scientific article published on 01 January 2002

Transient, recurrent, white matter lesions in X-linked Charcot-Marie-Tooth disease with novel connexin 32 mutation

artículo científico publicado en 2003

Unilateral cerebral hemisphere oedema as a peri-ictal phenomenon

artículo científico publicado en 2010

Update from the 2011 International Schwannomatosis Workshop: From genetics to diagnostic criteria.

artículo científico publicado en 2013

Upregulation of the Rac1/JNK signaling pathway in primary human schwannoma cells

scientific article published on 01 June 2003

Voltage-dependent membrane currents of cultured human neurofibromatosis type 2 Schwann cells

artículo científico publicado en 1998

[Central core myopathy: a juvenile and adult disease]

artículo científico publicado en 2007

Δ⁹-tetrahydrocannabinol (Δ⁹-THC) exerts a direct neuroprotective effect in a human cell culture model of Parkinson's disease.

artículo científico publicado en 2012

Lista de obras de Clemens O. Hanemann

A functional association between merlin and HEI10, a cell cycle regulator.

A multicentre evaluation of oropharyngeal secretion management practices in amyotrophic lateral sclerosis

A novel nonsense mutation in the ABC1 gene causes a severe syringomyelia-like phenotype of Tangier disease

ALS/MND meeting of the European ALS/MND group Reisensburg Castle 30 January – 1 February 2003

Achieving consensus for clinical trials: the REiNS International Collaboration.

Acquired rippling muscle disease in association with myasthenia gravis

Actin-rich protrusions and nonlocalized GTPase activation in Merlin-deficient schwannomas

Activation of ERK, AKT and JNK signalling pathways in human schwannomas in situ.

Activation of multiple growth factor signalling pathways is frequent in meningiomas

An Essential Role for the Tumor-Suppressor Merlin in Regulating Fatty Acid Synthesis

Artesunate induces necrotic cell death in schwannoma cells.

Axl/Gas6/NFκB signalling in schwannoma pathological proliferation, adhesion and survival.

Axon damage in CMT due to mutation in myelin protein P0

Balo's concentric sclerosis followed by MRI and positron emission tomography

Benign symmetric lipomatosis with axonal neuropathy and abnormalities in specific mitochondrial tRNA regions

CTF meeting 2012: Translation of the basic understanding of the biology and genetics of NF1, NF2, and schwannomatosis toward the development of effective therapies.

Cannabinoid Receptor and N‐acyl Phosphatidylethanolamine Phospholipase D—Evidence for Altered Expression in Multiple Sclerosis ⬇️

Cellular contaminants of adeno-associated virus vector stocks can enhance transduction.

Cellular prion protein (PrP(C)) in the development of Merlin-deficient tumours

Characterization of basal ganglia dysfunction in Leber 'plus' disease

Combined Inhibition of NEDD8-Activating Enzyme and mTOR Suppresses NF2 Loss-Driven Tumorigenesis.

Complicated hereditary spastic paraplegia with thin corpus callosum: Variation of phenotypic expression over time

Conclusions and future directions for the REiNS International Collaboration.

Congenital axonal neuropathy caused by deletions in the spinal muscular atrophy region

Consensus recommendations for current treatments and accelerating clinical trials for patients with neurofibromatosis type 2

Constitutive activation of the EGFR-STAT1 axis increases proliferation of meningioma tumor cells

Delta-9-tetrahydrocannabinol protects against MPP+ toxicity in SH-SY5Y cells by restoring proteins involved in mitochondrial biogenesis

DiPALS: Diaphragm Pacing in patients with Amyotrophic Lateral Sclerosis - a randomised controlled trial.

Differential gene expression between human schwannoma and control Schwann cells.

Enhanced proliferation and potassium conductance of Schwann cells isolated from NF2 schwannomas can be reduced by quinidine

Expression of c-Jun and Sox-2 in human schwannomas and traumatic neuromas.

Expression of decorin mRNA in the nervous system of rat.

FKRP (826C>A) frequently causes limb-girdle muscular dystrophy in German patients

Fludeoxyglucose F 18 positron emission tomography and computed tomography of a giant retroperitoneal schwannoma occurring in a patient with neurofibromatosis type 2.

Global Proteome and Phospho-proteome Analysis of Merlin-deficient Meningioma and Schwannoma Identifies PDLIM2 as a Novel Therapeutic Target.

Hereditary demyelinating neuropathies: from gene to disease.

Hereditary motor neuropathies and motor neuron diseases: which is which.

Heterozygous R1101K mutation of the DCTN1 gene in a family with ALS and FTD.

Impaired intercellular adhesion and immature adherens junctions in merlin-deficient human primary schwannoma cells

Improved culture methods to expand Schwann cells with altered growth behaviour from CMT1A patients

Insulin-like growth factor-binding protein-1 (IGFBP-1) regulates human schwannoma proliferation, adhesion and survival.

Integration and Comparison of Transcriptomic and Proteomic Data for Meningioma

Isolation and characterization of Schwann cells from neurofibromatosis type 2 patients

Lack of immune responses to immediate or delayed implanted allogeneic and xenogeneic Schwann cell suspensions ⬇️

Laryngospasm: an underdiagnosed symptom of X-linked spinobulbar muscular atrophy

Long-term culture and characterization of human neurofibroma-derived Schwann cells

Longitudinal evaluation of quality of life in 288 patients with neurofibromatosis 2.

Low affinity NGF receptor expression in CMT1A nerve biopsies of different disease stages

MR-pathologic comparison of the upper spinal cord in different motor neuron diseases

Magic but treatable? Tumours due to loss of merlin.

Management of sialorrhoea in motor neuron disease: a survey of current UK practice.

Measuring quality of life in ALS/MND: validation of the WHOQOL-BREF

Medulloblastoma in a patient with the PTPN11 p.Thr468Met mutation.

Merlin isoform 2 in neurofibromatosis type 2-associated polyneuropathy.

Merlin-deficient human tumors show loss of contact inhibition and activation of Wnt/β-catenin signaling linked to the PDGFR/Src and Rac/PAK pathways

Muscle injury in Guillain-Barré syndrome: a case report

Mutation-dependent alteration in cellular distribution of peripheral myelin protein 22 in nerve biopsies from Charcot-Marie-Tooth type 1A

Neurofibromatosis 2011: a report of the Children's Tumor Foundation annual meeting.

Neurofibromatosis type 1 with involvement of the enteric nerves.

Neuroligand-mediated calcium signaling in cultured human schwannoma cells

News on the genetics, epidemiology, medical care and translational research of Schwannomas

Nilotinib alone or in combination with selumetinib is a drug candidate for neurofibromatosis type 2.

P06.02ACTIVATION OF MULTIPLE GROWTH FACTOR SIGNALLING PATHWAYS IS FREQUENT IN MENINGIOMAS.

PAK kinase regulates Rac GTPase and is a potential target in human schwannomas

PMP22 expression in CMT1a neuropathy

PO76GROWTH FACTOR SIGNALLING PATHWAYS IN MENINGIOMAS IS COMMON AND PARTLY DEPENDS ON SUBTYPE ALLOWING FOR STRATIFICATION.

Pathogenesis of Charcot-Marie-Tooth 1A (CMT1A) neuropathy

Pathological adhesion of primary human schwannoma cells is dependent on altered expression of integrins.

Peripheral myelin protein-22 expression in Charcot-Marie-Tooth disease type 1a sural nerve biopsies

Phase 0 trial investigating the intratumoural concentration and activity of sorafenib in neurofibromatosis type 2

Point mutations of the p150 subunit of dynactin (DCTN1) gene in ALS.

Recent developments in neurofibromatoses and RASopathies: management, diagnosis and current and future therapeutic avenues.

Recurrent hematomas following craniotomy for traumatic intracranial mass

Reduced apoptosis rates in human schwannomas.

Schwann cell differentiation in Charcot-Marie-Tooth disease type 1A (CMT1A): normal number of myelinating Schwann cells in young CMT1A patients and neural cell adhesion molecule expression in onion bulbs

Schwannomas and their pathogenesis

Secondary axon atrophy and neurological dysfunction in demyelinating neuropathies.

Signal therapy of NF1-deficient tumor xenograft in mice by the anti-PAK1 drug FK228.

Spinal neurofibromatosis without café-au-lait macules in two families with null mutations of the NF1 gene.