Lista de obras - Suzanne M Cutts - Dominio Público Uruguay

A gel mobility shift assay for probing the effect of drug-DNA adducts on DNA-binding proteins.

artículo científico publicado en 1997

A molecular understanding of mitoxantrone-DNA adduct formation: effect of cytosine methylation and flanking sequences

artículo científico

A novel valproic acid prodrug as an anticancer agent that enhances doxorubicin anticancer activity and protects normal cells against its toxicity in vitro and in vivo

artículo científico publicado en 2014

ABT-737 overcomes Bcl-2 mediated resistance to doxorubicin-DNA adducts

artículo científico publicado en 2009

Activation of DNA damage response pathways as a consequence of anthracycline-DNA adduct formation

artículo científico publicado en 2012

Activation of clinically used anthracyclines by the formaldehyde-releasing prodrug pivaloyloxymethyl butyrate

artículo científico publicado en 2007

An oligonucleotide crosslinking assay for the analysis of individual drug-binding sites.

artículo científico publicado en 1997

Anthracyclines ⬇️

scholarly article

Barminomycin functions as a potent pre-activated analogue of Adriamycin ⬇️

artículo científico publicado el 28 de noviembre de 2001

Binding of pixantrone to DNA at CpA dinucleotide sequences and bulge structures

artículo científico

Cloning, expression, and promoter structure of a mammalian inner centromere protein (INCENP).

artículo científico publicado en 1999

Construction of neocentromere-based human minichromosomes by telomere-associated chromosomal truncation.

artículo científico publicado en 2001

CpG methylation potentiates pixantrone and doxorubicin-induced DNA damage and is a marker of drug sensitivity

artículo científico publicado en 2009

DNA binding by pixantrone

artículo científico publicado en 2010

DNA repair in response to anthracycline-DNA adducts: a role for both homologous recombination and nucleotide excision repair.

artículo científico publicado en 2007

Design, synthesis, and DNA sequence selectivity of formaldehyde-mediated DNA-adducts of the novel N -(4-aminobutyl) acridine-4-carboxamide

artículo científico publicado en 2014

Detection of Adriamycin-DNA adducts by accelerator mass spectrometry at clinically relevant Adriamycin concentrations

artículo científico publicado en 2008

Detection of adriamycin-DNA adducts by accelerator mass spectrometry

artículo científico publicado en 2010

Development of pluronic micelle-encapsulated doxorubicin and formaldehyde-releasing prodrugs for localized anticancer chemotherapy

artículo científico publicado en 2009

Disparate impact of butyroyloxymethyl diethylphosphate (AN-7), a histone deacetylase inhibitor, and doxorubicin in mice bearing a mammary tumor

artículo científico publicado en 2012

Doxorubicin-DNA adducts induce a non-topoisomerase II-mediated form of cell death

artículo científico publicado en 2006

Effects of histone deacetylase inhibitory prodrugs on epigenetic changes and DNA damage response in tumor and heart of glioblastoma xenograft

artículo científico publicado en 2017

Encapsulation of Mitoxantrone within Cucurbit[8]uril Decreases Toxicity and Enhances Survival in a Mouse Model of Cancer

artículo científico publicado en 2017

Erratum: Factors determining the stability, size distribution, and cellular accumulation of small, monodisperse chitosan nanoparticles as candidate vectors for anticancer drug delivery: application to the passive encapsulation of [(14)C]-doxorubicin

scholarly article published in Nanotechnology, Science and Applications

Factors determining the stability, size distribution, and cellular accumulation of small, monodisperse chitosan nanoparticles as candidate vectors for anticancer drug delivery: application to the passive encapsulation of [(14)C]-doxorubicin

artículo científico publicado en 2015

Formaldehyde-activated Pixantrone is a monofunctional DNA alkylator that binds selectively to CpG and CpA doublets

artículo científico publicado en 2008

Formaldehyde-releasing prodrugs specifically affect cancer cells by depletion of intracellular glutathione and augmentation of reactive oxygen species

artículo científico publicado en 2007

Formation of adriamycin--DNA adducts in vitro.

artículo científico publicado en 1994

High-resolution transcription assay for probing drug-DNA interactions at individual drug sites

artículo científico publicado en 2001

In vitro transcription assay for resolution of drug-DNA interactions at defined DNA sequences

artículo científico publicado en 2010

In vivo and in vitro antitumor activity of butyroyloxymethyl-diethyl phosphate (AN-7), a histone deacetylase inhibitor, in human prostate cancer

artículo científico publicado en 2005

Inhibition of Bcl-2 or IAP proteins does not provoke mutations in surviving cells

artículo científico publicado en 2015

Interstrand cross-linking by adriamycin in nuclear and mitochondrial DNA of MCF-7 cells

artículo científico publicado en 2000

Isolation and structural analysis of the covalent adduct formed between a bis-amino mitoxantrone analogue and DNA: a pathway to major-minor groove cross-linked adducts

artículo científico publicado en 2016

M2, a novel anthracenedione, elicits a potent DNA damage response that can be subverted through checkpoint kinase inhibition to generate mitotic catastrophe

artículo científico publicado en 2011

Mitoxantrone mediates demethylation and reexpression of cyclin d2, estrogen receptor and 14.3.3sigma in breast cancer cells.

artículo científico publicado en 2003

Mitoxantrone, More than Just Another Topoisomerase II Poison.

artículo científico

Mode of interaction between butyroyloxymethyl-diethyl phosphate (AN-7) and doxorubicin in MCF-7 and resistant MCF-7/Dx cell lines

artículo científico publicado en 2006

New anthracenedione derivatives with improved biological activity by virtue of stable drug-DNA adduct formation

artículo científico publicado en 2010

Pixantrone can be activated by formaldehyde to generate a potent DNA adduct forming agent

artículo científico publicado en 2007

Potential Therapeutic Advantages of Doxorubicin when Activated by Formaldehyde to Function as a DNA Adduct-Forming Agent

artículo científico publicado en 2015

Processing of anthracycline-DNA adducts via DNA replication and interstrand crosslink repair pathways

artículo científico publicado en 2012

Recent advances in understanding and exploiting the activation of anthracyclines by formaldehyde.

artículo científico publicado en 2005

Reversible and formaldehyde-mediated covalent binding of a bis-amino mitoxantrone analogue to DNA.

artículo científico publicado en 2016

The cardio-protecting agent and topoisomerase II catalytic inhibitor sobuzoxane enhances doxorubicin-DNA adduct mediated cytotoxicity

scientific article published on 27 June 2007

The histone deacetylase inhibitor butyroyloxymethyl diethylphosphate (AN-7) protects normal cells against toxicity of anticancer agents while augmenting their anticancer activity

artículo científico publicado en 2010

The hydroxyl epimer of doxorubicin controls the rate of formation of cytotoxic anthracycline-DNA adducts

artículo científico publicado en 2012

The power and potential of doxorubicin-DNA adducts

artículo científico publicado en 2005

The role of intracellularly released formaldehyde and butyric acid in the anticancer activity of acyloxyalkyl esters.

artículo científico publicado en 2005

The selectivty and anti-metastatic activity of oral bioavailable butyric acid prodrugs

artículo científico publicado en 2006

ToF-SIMS and Machine Learning for Single-Pixel Molecular Discrimination of an Acrylate Polymer Microarray

artículo científico publicado en 2020

Use of oligonucleotides to define the site of interstrand cross-links induced by Adriamycin.

artículo científico publicado en 1995

Visualizing ToF-SIMS Hyperspectral Imaging Data Using Color-Tagged Toroidal Self-Organizing Maps

artículo científico publicado en 2019

Lista de obras de Suzanne M Cutts

A gel mobility shift assay for probing the effect of drug-DNA adducts on DNA-binding proteins.

A molecular understanding of mitoxantrone-DNA adduct formation: effect of cytosine methylation and flanking sequences

A novel valproic acid prodrug as an anticancer agent that enhances doxorubicin anticancer activity and protects normal cells against its toxicity in vitro and in vivo

ABT-737 overcomes Bcl-2 mediated resistance to doxorubicin-DNA adducts

Activation of DNA damage response pathways as a consequence of anthracycline-DNA adduct formation

Activation of clinically used anthracyclines by the formaldehyde-releasing prodrug pivaloyloxymethyl butyrate

An oligonucleotide crosslinking assay for the analysis of individual drug-binding sites.

Anthracyclines ⬇️

Barminomycin functions as a potent pre-activated analogue of Adriamycin ⬇️

Binding of pixantrone to DNA at CpA dinucleotide sequences and bulge structures

Cloning, expression, and promoter structure of a mammalian inner centromere protein (INCENP).

Construction of neocentromere-based human minichromosomes by telomere-associated chromosomal truncation.

CpG methylation potentiates pixantrone and doxorubicin-induced DNA damage and is a marker of drug sensitivity

DNA binding by pixantrone

DNA repair in response to anthracycline-DNA adducts: a role for both homologous recombination and nucleotide excision repair.

Design, synthesis, and DNA sequence selectivity of formaldehyde-mediated DNA-adducts of the novel N -(4-aminobutyl) acridine-4-carboxamide

Detection of Adriamycin-DNA adducts by accelerator mass spectrometry at clinically relevant Adriamycin concentrations

Detection of adriamycin-DNA adducts by accelerator mass spectrometry

Development of pluronic micelle-encapsulated doxorubicin and formaldehyde-releasing prodrugs for localized anticancer chemotherapy

Disparate impact of butyroyloxymethyl diethylphosphate (AN-7), a histone deacetylase inhibitor, and doxorubicin in mice bearing a mammary tumor

Doxorubicin-DNA adducts induce a non-topoisomerase II-mediated form of cell death

Effects of histone deacetylase inhibitory prodrugs on epigenetic changes and DNA damage response in tumor and heart of glioblastoma xenograft

Encapsulation of Mitoxantrone within Cucurbit[8]uril Decreases Toxicity and Enhances Survival in a Mouse Model of Cancer

Erratum: Factors determining the stability, size distribution, and cellular accumulation of small, monodisperse chitosan nanoparticles as candidate vectors for anticancer drug delivery: application to the passive encapsulation of [(14)C]-doxorubicin

Factors determining the stability, size distribution, and cellular accumulation of small, monodisperse chitosan nanoparticles as candidate vectors for anticancer drug delivery: application to the passive encapsulation of [(14)C]-doxorubicin

Formaldehyde-activated Pixantrone is a monofunctional DNA alkylator that binds selectively to CpG and CpA doublets

Formaldehyde-releasing prodrugs specifically affect cancer cells by depletion of intracellular glutathione and augmentation of reactive oxygen species

Formation of adriamycin--DNA adducts in vitro.

High-resolution transcription assay for probing drug-DNA interactions at individual drug sites

In vitro transcription assay for resolution of drug-DNA interactions at defined DNA sequences

In vivo and in vitro antitumor activity of butyroyloxymethyl-diethyl phosphate (AN-7), a histone deacetylase inhibitor, in human prostate cancer

Inhibition of Bcl-2 or IAP proteins does not provoke mutations in surviving cells

Interstrand cross-linking by adriamycin in nuclear and mitochondrial DNA of MCF-7 cells

Isolation and structural analysis of the covalent adduct formed between a bis-amino mitoxantrone analogue and DNA: a pathway to major-minor groove cross-linked adducts

M2, a novel anthracenedione, elicits a potent DNA damage response that can be subverted through checkpoint kinase inhibition to generate mitotic catastrophe

Mitoxantrone mediates demethylation and reexpression of cyclin d2, estrogen receptor and 14.3.3sigma in breast cancer cells.

Mitoxantrone, More than Just Another Topoisomerase II Poison.

Mode of interaction between butyroyloxymethyl-diethyl phosphate (AN-7) and doxorubicin in MCF-7 and resistant MCF-7/Dx cell lines

New anthracenedione derivatives with improved biological activity by virtue of stable drug-DNA adduct formation

Pixantrone can be activated by formaldehyde to generate a potent DNA adduct forming agent

Potential Therapeutic Advantages of Doxorubicin when Activated by Formaldehyde to Function as a DNA Adduct-Forming Agent

Processing of anthracycline-DNA adducts via DNA replication and interstrand crosslink repair pathways

Recent advances in understanding and exploiting the activation of anthracyclines by formaldehyde.

Reversible and formaldehyde-mediated covalent binding of a bis-amino mitoxantrone analogue to DNA.

The cardio-protecting agent and topoisomerase II catalytic inhibitor sobuzoxane enhances doxorubicin-DNA adduct mediated cytotoxicity

The histone deacetylase inhibitor butyroyloxymethyl diethylphosphate (AN-7) protects normal cells against toxicity of anticancer agents while augmenting their anticancer activity

The hydroxyl epimer of doxorubicin controls the rate of formation of cytotoxic anthracycline-DNA adducts

The power and potential of doxorubicin-DNA adducts

The role of intracellularly released formaldehyde and butyric acid in the anticancer activity of acyloxyalkyl esters.

The selectivty and anti-metastatic activity of oral bioavailable butyric acid prodrugs

ToF-SIMS and Machine Learning for Single-Pixel Molecular Discrimination of an Acrylate Polymer Microarray

Use of oligonucleotides to define the site of interstrand cross-links induced by Adriamycin.

Visualizing ToF-SIMS Hyperspectral Imaging Data Using Color-Tagged Toroidal Self-Organizing Maps