Lista de obras - Jesús M. Peregrina - Dominio Público Uruguay

A Biomimetic Approach to Lanthionines

scientific article published on 16 December 2011

A Domino Michael/Dieckmann Process as an Entry to α-(Hydroxymethyl)glutamic Acid

article

A Double Diastereoselective Michael-Type Addition as an Entry to Conformationally Restricted Tn Antigen Mimics

artículo científico publicado en 2013

A Late-Stage Synthetic Approach to Lanthionine-Containing Peptides via S-Alkylation on Cyclic Sulfamidates Promoted by Molecular Sieves

scientific article published on 14 November 2018

A convenient enantioselective synthesis of (S)-alpha-trifluoromethylisoserine

artículo científico publicado en 2005

A novel multistep mechanism for the stereocontrolled ring opening of hindered sulfamidates: mild, green, and efficient reactivity with alcohols

artículo científico publicado en 2009

A thorough study on the use of quantitative 1H NMR in Rioja red wine fermentation processes.

artículo científico publicado en 2009

Asymmetric hetero Diels-Alder as an access to carbacephams.

artículo científico publicado en 2002

Bifunctional Chiral Dehydroalanines for Peptide Coupling and Stereoselective S-Michael Addition.

artículo científico publicado en 2016

Bioorthogonal Self-Immolative Linker Based on Grob Fragmentation

artículo científico publicado en 2021

Cell-Penetrating Peptides Containing Fluorescent d -Cysteines

artículo científico publicado en 2018

Conformational analysis of 2-substituted cyclobutane-alpha-amino acid derivatives. A synergistic experimental and computational study

artículo científico publicado en 2006

Conformational analysis of N-Boc-N,O-isopropylidene-α-serinals. A combined DFT and NMR study

Conformational effects of the non-natural alpha-methylserine on small peptides and glycopeptides.

artículo científico publicado en 2009

Conformational preferences of chiral acyclic homooligomeric β(2,2)-peptides

artículo científico publicado en 2014

Conformationally-locked C-glycosides: tuning aglycone interactions for optimal chaperone behaviour in Gaucher fibroblasts

artículo científico publicado en 2016

Cyclohexane ring as a tool to select the presentation of the carbohydrate moiety in glycosyl amino acids

scientific article published on 01 March 2012

Deciphering the Non-Equivalence of Serine and Threonine O-Glycosylation Points: Implications for Molecular Recognition of the Tn Antigen by an anti-MUC1 Antibody

artículo científico publicado en 2015

Design of α-S-Neoglycopeptides Derived from MUC1 with a Flexible and Solvent-Exposed Sugar Moiety

artículo científico publicado en 2016

Detection of tumor-associated glycopeptides by lectins: the peptide context modulates carbohydrate recognition

artículo científico publicado en 2015

Dynamic interplay between catalytic and lectin domains of GalNAc-transferases modulates protein O-glycosylation.

artículo científico publicado en 2015

Effect of beta-O-glucosylation on L-Ser and L-Thr diamides: a bias toward alpha-helical conformations.

artículo científico publicado en 2006

Enantiopure synthesis of all four stereoisomers of carbapenam-3-carboxylic acid methyl ester.

artículo científico publicado en 2003

Enantioselective Synthesis ofS-Linked Glycosyl-β2,2-Amino Acid Derivatives by SN2 Reaction with Hindered Sulfamidates

Engineering O-Glycosylation Points in Non-extended Peptides: Implications for the Molecular Recognition of Short Tumor-Associated Glycopeptides

artículo científico publicado en 2011

Evidence of metabolic transformations of amino acids into higher alcohols through (13)C NMR studies of wine alcoholic fermentation

artículo científico publicado en 2010

Highly chemoselective reactions on hindered sulfamidates with oxygenated nucleophiles

article published in 2008

Influence of amino acid stereocenters on the formation of bicyclic N,O-acetals.

artículo científico publicado en 2014

Insights into the geometrical features underlying beta-O-GlcNAc glycosylation: water pockets drastically modulate the interactions between the carbohydrate and the peptide backbone

artículo científico publicado en 2009

Investigations of La Rioja terroir for wine production using 1H NMR metabolomics

scientific article published on 21 March 2012

Lanthionine Peptides by S-Alkylation with Substituted Cyclic Sulfamidates Promoted by Activated Molecular Sieves: Effects of the Sulfamidate Structure on the Yield

scientific article published on 01 November 2019

Mechanistic study of the ring-size modulation in Michael–Dieckmann type reactions of 2-acylaminoacrylates with ketene diethyl acetal

Molecular recognition of β-O-GlcNAc glycopeptides by a lectin-like receptor: binding modulation by the underlying Ser or Thr amino acids.

artículo científico publicado en 2011

Mucin architecture behind the immune response: design, evaluation and conformational analysis of an antitumor vaccine derived from an unnatural MUC1 fragment.

artículo científico publicado en 2015

NMR study of histidine metabolism during alcoholic and malolactic fermentations of wine and their influence on histamine production

scientific article published on 23 September 2013

New insights into alpha-GalNAc-Ser motif: influence of hydrogen bonding versus solvent interactions on the preferred conformation.

artículo científico publicado en 2006

New syntheses of enantiopure 2-methyl isoserines

article published in 2004

Non-natural amino acids as modulating agents of the conformational space of model glycopeptides

artículo científico publicado en 2008

Nuclear Magnetic Resonance (NMR) as a tool for the study of the metabolism of Rickettsia slovaca

artículo científico publicado en 2015

Nuclear Magnetic Resonance Applied to Antimicrobial Drug Susceptibility ⬇️

artículo científico publicado el 1 de abril de 2013

Preparation and Synthetic Applications of (S)- and (R)-N-Boc-N,O-isopropylidene-alpha-methylserinals: Asymmetric Synthesis of (S)- and (R)-2-Amino-2-methylbutanoic Acids (Iva)

artículo científico publicado en 1999

Principles of mucin structure: implications for the rational design of cancer vaccines derived from MUC1-glycopeptides.

artículo científico publicado en 2017

Proton Nuclear Magnetic Resonance Spectroscopy as a Technique for Gentamicin Drug Susceptibility Studies with Escherichia coli ATCC 25922.

artículo científico publicado en 2015

Quaternary chiral β(2,2)-amino acids with pyridinium and imidazolium substituents

artículo científico publicado en 2012

Rational design of a Tn antigen mimic

artículo científico publicado en 2011

Regioselective ring-opening metathesis-cross metathesis of bridgehead-substituted 7-azanorbornene

scientific article published on 09 March 2007

Ring-rearrangement metathesis of 1-substituted 7-azanorbornenes as an entry to 1-azaspiro[4.5]decane systems

scientific article published on 05 April 2011

Role of the Countercation in Diastereoselective Alkylations of Pyramidalized Bicyclic Serine Enolates. An Easy Approach to α-Benzylserine†

scientific article published on 08 June 2007

S(N)2 reaction of sulfur nucleophiles with hindered sulfamidates: enantioselective synthesis of alpha-methylisocysteine

artículo científico publicado en 2006

S-Michael additions to chiral dehydroalanines as an entry to glycosylated cysteines and a sulfa-Tn antigen mimic

artículo científico publicado en 2014

SN2 vs E2 on Quaternary Centers: An Easy Approach to Chiral β2,2-Amino Acids from Cyclic Sulfamidates

article by alberto avenoza et al published 2 March 2005 in Phosphorus, Sulfur, and Silicon and the Related Elements

Selective Michael-aldol reaction by use of sterically hindered aluminum aryloxides as Lewis acids: an easy approach to cyclobutane amino acids

artículo científico publicado en 2005

Selective modification of sulfamidate-containing peptides

artículo científico publicado en 2020

Serine versus threonine glycosylation with α-O-GalNAc: unexpected selectivity in their molecular recognition with lectins.

artículo científico publicado en 2014

Serine versus threonine glycosylation: the methyl group causes a drastic alteration on the carbohydrate orientation and on the surrounding water shell

artículo científico publicado en 2007

Stabilizing unusual conformations in small peptides and glucopeptides using a hydroxylated cyclobutane amino acid.

artículo científico publicado en 2009

Stereocontrolled Ring-Opening of a Hindered Sulfamidate with Nitrogen-Containing Aromatic Heterocycles: Synthesis of Chiral Quaternary Imidazole Derivatives

scientific article published on 28 April 2011

Stereoselective Synthesis of Orthogonally Protected α-Methylnorlanthionine

scientific article published on 01 June 2006

Structure-Based Design of Potent Tumor-Associated Antigens: Modulation of Peptide Presentation by Single-Atom O/S or O/Se Substitutions at the Glycosidic Linkage

scientific article published on 20 February 2019

Substituent Effects on the Reactivity of Cyclic Tertiary Sulfamidates

artículo científico publicado en 2017

Substrate-guided front-face reaction revealed by combined structural snapshots and metadynamics for the polypeptide N-acetylgalactosaminyltransferase 2

artículo científico publicado en 2014

Synthesis and conformational analysis of hybrid α/β-dipeptides incorporating S-glycosyl-β(2,2)-amino acids

artículo científico publicado en 2014

Synthesis and conformational analysis of neoglycoconjugates derived from O- and S-glucose.

artículo científico publicado en 2013

Synthesis of Mixed α/β2,2-Peptides by Site-Selective Ring-Opening of Cyclic Quaternary Sulfamidates

artículo científico publicado en 2015

Synthesis of Nβ-Substituted α,β-Diamino Acids via Stereoselective N-Michael Additions to a Chiral Bicyclic Dehydroalanine

artículo científico publicado en 2020

Synthesis of azabicyclo[2.2.n]alkane systems as analogues of 3-[1-methyl-2-(S)-pyrrolidinyl- methoxy]pyridine (A-84543).

artículo científico publicado en 2007

Synthesis of new conformationally rigid phenylalanine analogues

Synthesis, conformational analysis and in vivo assays of an anti-cancer vaccine that features an unnatural antigen based on an sp2-iminosugar fragment

artículo científico publicado en 2020

The Use of Fluoroproline in MUC1 Antigen Enables Efficient Detection of Antibodies in Patients with Prostate Cancer.

artículo científico publicado en 2017

The interdomain flexible linker of the polypeptide GalNAc transferases dictates their long-range glycosylation preferences

artículo científico publicado en 2017

The nature and sequence of the amino acid aglycone strongly modulates the conformation and dynamics effects of Tn antigen's clusters

artículo científico publicado en 2009

Theoretical Evidence for Pyramidalized Bicyclic Serine Enolates in Highly Diastereoselective Alkylations

article

Time course of the evolution of malic and lactic acids in the alcoholic and malolactic fermentation of grape must by quantitative 1H NMR (qHNMR) spectroscopy

artículo científico publicado en 2006

Tn Antigen Mimics by Ring-Opening of Chiral Cyclic Sulfamidates with Carbohydrate C1-S- and C1-O-Nucleophiles

artículo científico publicado en 2018

Toward Enantiomerically Pure β-Seleno-α-amino Acids via Stereoselective Se-Michael Additions to Chiral Dehydroalanines

artículo científico publicado en 2020

Understanding the unusual regioselectivity in the nucleophilic ring-opening reactions of gem-disubstituted cyclic sulfates. Experimental and theoretical studies

scientific article published on 01 May 2003

Water Sculpts the Distinctive Shapes and Dynamics of the Tumor-Associated Carbohydrate Tn Antigens: Implications for Their Molecular Recognition

scientific article published on 30 July 2018

Lista de obras de Jesús M. Peregrina

A Biomimetic Approach to Lanthionines

A Domino Michael/Dieckmann Process as an Entry to α-(Hydroxymethyl)glutamic Acid

A Double Diastereoselective Michael-Type Addition as an Entry to Conformationally Restricted Tn Antigen Mimics

A Late-Stage Synthetic Approach to Lanthionine-Containing Peptides via S-Alkylation on Cyclic Sulfamidates Promoted by Molecular Sieves

A convenient enantioselective synthesis of (S)-alpha-trifluoromethylisoserine

A novel multistep mechanism for the stereocontrolled ring opening of hindered sulfamidates: mild, green, and efficient reactivity with alcohols

A thorough study on the use of quantitative 1H NMR in Rioja red wine fermentation processes.

Asymmetric hetero Diels-Alder as an access to carbacephams.

Bifunctional Chiral Dehydroalanines for Peptide Coupling and Stereoselective S-Michael Addition.

Bioorthogonal Self-Immolative Linker Based on Grob Fragmentation

Cell-Penetrating Peptides Containing Fluorescent d -Cysteines

Conformational analysis of 2-substituted cyclobutane-alpha-amino acid derivatives. A synergistic experimental and computational study

Conformational analysis of N-Boc-N,O-isopropylidene-α-serinals. A combined DFT and NMR study

Conformational effects of the non-natural alpha-methylserine on small peptides and glycopeptides.

Conformational preferences of chiral acyclic homooligomeric β(2,2)-peptides

Conformationally-locked C-glycosides: tuning aglycone interactions for optimal chaperone behaviour in Gaucher fibroblasts

Cyclohexane ring as a tool to select the presentation of the carbohydrate moiety in glycosyl amino acids

Deciphering the Non-Equivalence of Serine and Threonine O-Glycosylation Points: Implications for Molecular Recognition of the Tn Antigen by an anti-MUC1 Antibody

Design of α-S-Neoglycopeptides Derived from MUC1 with a Flexible and Solvent-Exposed Sugar Moiety

Detection of tumor-associated glycopeptides by lectins: the peptide context modulates carbohydrate recognition

Dynamic interplay between catalytic and lectin domains of GalNAc-transferases modulates protein O-glycosylation.

Effect of beta-O-glucosylation on L-Ser and L-Thr diamides: a bias toward alpha-helical conformations.

Enantiopure synthesis of all four stereoisomers of carbapenam-3-carboxylic acid methyl ester.

Enantioselective Synthesis ofS-Linked Glycosyl-β2,2-Amino Acid Derivatives by SN2 Reaction with Hindered Sulfamidates

Engineering O-Glycosylation Points in Non-extended Peptides: Implications for the Molecular Recognition of Short Tumor-Associated Glycopeptides

Evidence of metabolic transformations of amino acids into higher alcohols through (13)C NMR studies of wine alcoholic fermentation

Highly chemoselective reactions on hindered sulfamidates with oxygenated nucleophiles

Influence of amino acid stereocenters on the formation of bicyclic N,O-acetals.

Insights into the geometrical features underlying beta-O-GlcNAc glycosylation: water pockets drastically modulate the interactions between the carbohydrate and the peptide backbone

Investigations of La Rioja terroir for wine production using 1H NMR metabolomics

Lanthionine Peptides by S-Alkylation with Substituted Cyclic Sulfamidates Promoted by Activated Molecular Sieves: Effects of the Sulfamidate Structure on the Yield

Mechanistic study of the ring-size modulation in Michael–Dieckmann type reactions of 2-acylaminoacrylates with ketene diethyl acetal

Molecular recognition of β-O-GlcNAc glycopeptides by a lectin-like receptor: binding modulation by the underlying Ser or Thr amino acids.

Mucin architecture behind the immune response: design, evaluation and conformational analysis of an antitumor vaccine derived from an unnatural MUC1 fragment.

NMR study of histidine metabolism during alcoholic and malolactic fermentations of wine and their influence on histamine production

New insights into alpha-GalNAc-Ser motif: influence of hydrogen bonding versus solvent interactions on the preferred conformation.

New syntheses of enantiopure 2-methyl isoserines

Non-natural amino acids as modulating agents of the conformational space of model glycopeptides

Nuclear Magnetic Resonance (NMR) as a tool for the study of the metabolism of Rickettsia slovaca

Nuclear Magnetic Resonance Applied to Antimicrobial Drug Susceptibility ⬇️

Preparation and Synthetic Applications of (S)- and (R)-N-Boc-N,O-isopropylidene-alpha-methylserinals: Asymmetric Synthesis of (S)- and (R)-2-Amino-2-methylbutanoic Acids (Iva)

Principles of mucin structure: implications for the rational design of cancer vaccines derived from MUC1-glycopeptides.

Proton Nuclear Magnetic Resonance Spectroscopy as a Technique for Gentamicin Drug Susceptibility Studies with Escherichia coli ATCC 25922.

Quaternary chiral β(2,2)-amino acids with pyridinium and imidazolium substituents

Rational design of a Tn antigen mimic

Regioselective ring-opening metathesis-cross metathesis of bridgehead-substituted 7-azanorbornene

Ring-rearrangement metathesis of 1-substituted 7-azanorbornenes as an entry to 1-azaspiro[4.5]decane systems

Role of the Countercation in Diastereoselective Alkylations of Pyramidalized Bicyclic Serine Enolates. An Easy Approach to α-Benzylserine†

S(N)2 reaction of sulfur nucleophiles with hindered sulfamidates: enantioselective synthesis of alpha-methylisocysteine

S-Michael additions to chiral dehydroalanines as an entry to glycosylated cysteines and a sulfa-Tn antigen mimic

SN2 vs E2 on Quaternary Centers: An Easy Approach to Chiral β2,2-Amino Acids from Cyclic Sulfamidates

Selective Michael-aldol reaction by use of sterically hindered aluminum aryloxides as Lewis acids: an easy approach to cyclobutane amino acids

Selective modification of sulfamidate-containing peptides

Serine versus threonine glycosylation with α-O-GalNAc: unexpected selectivity in their molecular recognition with lectins.

Serine versus threonine glycosylation: the methyl group causes a drastic alteration on the carbohydrate orientation and on the surrounding water shell

Stabilizing unusual conformations in small peptides and glucopeptides using a hydroxylated cyclobutane amino acid.

Stereocontrolled Ring-Opening of a Hindered Sulfamidate with Nitrogen-Containing Aromatic Heterocycles: Synthesis of Chiral Quaternary Imidazole Derivatives

Stereoselective Synthesis of Orthogonally Protected α-Methylnorlanthionine

Structure-Based Design of Potent Tumor-Associated Antigens: Modulation of Peptide Presentation by Single-Atom O/S or O/Se Substitutions at the Glycosidic Linkage

Substituent Effects on the Reactivity of Cyclic Tertiary Sulfamidates

Substrate-guided front-face reaction revealed by combined structural snapshots and metadynamics for the polypeptide N-acetylgalactosaminyltransferase 2

Synthesis and conformational analysis of hybrid α/β-dipeptides incorporating S-glycosyl-β(2,2)-amino acids

Synthesis and conformational analysis of neoglycoconjugates derived from O- and S-glucose.

Synthesis of Mixed α/β2,2-Peptides by Site-Selective Ring-Opening of Cyclic Quaternary Sulfamidates

Synthesis of Nβ-Substituted α,β-Diamino Acids via Stereoselective N-Michael Additions to a Chiral Bicyclic Dehydroalanine

Synthesis of azabicyclo[2.2.n]alkane systems as analogues of 3-[1-methyl-2-(S)-pyrrolidinyl- methoxy]pyridine (A-84543).

Synthesis of new conformationally rigid phenylalanine analogues

Synthesis, conformational analysis and <i>in vivo</i> assays of an anti-cancer vaccine that features an unnatural antigen based on an sp<sup>2</sup>-iminosugar fragment

The Use of Fluoroproline in MUC1 Antigen Enables Efficient Detection of Antibodies in Patients with Prostate Cancer.

The interdomain flexible linker of the polypeptide GalNAc transferases dictates their long-range glycosylation preferences

The nature and sequence of the amino acid aglycone strongly modulates the conformation and dynamics effects of Tn antigen's clusters

Theoretical Evidence for Pyramidalized Bicyclic Serine Enolates in Highly Diastereoselective Alkylations

Time course of the evolution of malic and lactic acids in the alcoholic and malolactic fermentation of grape must by quantitative 1H NMR (qHNMR) spectroscopy

Tn Antigen Mimics by Ring-Opening of Chiral Cyclic Sulfamidates with Carbohydrate C1-S- and C1-O-Nucleophiles

Toward Enantiomerically Pure β-Seleno-α-amino Acids via Stereoselective <i>Se</i>-Michael Additions to Chiral Dehydroalanines

Understanding the unusual regioselectivity in the nucleophilic ring-opening reactions of gem-disubstituted cyclic sulfates. Experimental and theoretical studies

Water Sculpts the Distinctive Shapes and Dynamics of the Tumor-Associated Carbohydrate Tn Antigens: Implications for Their Molecular Recognition

α-Alkylation versus retro-O-Michael/γ-alkylation of bicyclic N,O-acetals: an entry to α-methylthreonine