Lista de obras - Paul A. Keller - Dominio Público Uruguay

A mild and general method for the synthesis of 5-substituted and 5,5-disubstituted fulleroprolines

scientific article published on 21 February 2008

A new methodology for the simulation of flexible protein-ligand interactions

scientific article published on 21 November 2006

A new protoberberine alkaloid from Meconopsis simplicifolia (D. Don) Walpers with potent antimalarial activity against a multidrug resistant Plasmodium falciparum strain

artículo científico publicado en 2013

A twist of nature--the significance of atropisomers in biological systems

artículo científico

Alkaloids from the root of Indonesian Annona muricata L

scientific article published on 08 July 2019

An assessment of the Bhutanese traditional medicine for its ethnopharmacology, ethnobotany and ethnoquality: Textual understanding and the current practices

artículo científico publicado en 2013

An improved synthesis of pyrido[2,3-d]pyrimidin-4(1H)-ones and their antimicrobial activity

artículo científico publicado en 2018

Anilinopyrimidines as novel antituberculosis agents.

artículo científico publicado en 2003

Antarctic Moss Biflavonoids Show High Antioxidant and Ultraviolet-Screening Activity

artículo científico publicado en 2017

Anti-Infective and Anti-Cancer Properties of the Annona Species: Their Ethnomedicinal Uses, Alkaloid Diversity, and Pharmacological Activities

scientific article published on 03 December 2019

Anti-cancer Evaluation of Depsides Isolated from Indonesian Folious Lichens: Physcia millegrana, Parmelia dilatata and Parmelia aurulenta

scientific article published on 08 October 2020

Antimalarial alkaloids from a Bhutanese traditional medicinal plant Corydalis dubia

artículo científico publicado en 2012

Atroposelective synthesis of axially chiral biaryl compounds

artículo científico publicado en 2005

Binaphthyl scaffolded peptoids via ring-closing metathesis reactions and their anti-bacterial activities.

artículo científico publicado en 2009

Binaphthyl-1,2,3-triazole peptidomimetics with activity against Clostridium difficile and other pathogenic bacteria.

artículo científico publicado en 2015

Binaphthyl-anchored antibacterial tripeptide derivatives with hydrophobic C-terminal amino acid variations.

artículo científico publicado en 2012

Binaphthyl-based dicationic peptoids with therapeutic potential.

artículo científico publicado en 2010

Bioactive Discovery in the New Millennium--A Joint RACI, JMGM, FACS and MM2003 Conference. 5-9 February 2003, Lorne, Australia

artículo científico publicado en 2003

Bioactive glycosides from the African medicinal plant Boerhavia erecta L.

artículo científico publicado en 2015

Cascade reactions of indigo with oxiranes and aziridines: efficient access to dihydropyrazinodiindoles and spiro-oxazocinodiindoles

artículo científico publicado en 2018

Cationic biaryl 1,2,3-triazolyl peptidomimetic amphiphiles targeting Clostridioides (Clostridium) difficile: Synthesis, antibacterial evaluation and an in vivo C. difficile infection model

artículo científico publicado en 2019

Cationic biaryl 1,2,3-triazolyl peptidomimetic amphiphiles: synthesis, antibacterial evaluation and preliminary mechanism of action studies

artículo científico publicado en 2019

Chikungunya virus: emerging targets and new opportunities for medicinal chemistry

artículo científico publicado en 2013

Combining structure-based drug design and pharmacophores

artículo científico publicado en 2005

Control of hepatitis C: a medicinal chemistry perspective

artículo científico publicado en 2005

Current and Ongoing Developments in Targeting Clostridioides difficile Infection and Recurrence

artículo científico publicado en 2024

Cyclic Phosphine Oxides and Phosphinamides from Di-Grignard Reagents and Phosphonic Dichlorides: Modular Access to Annulated Phospholanes

artículo científico publicado en 2015

Dengue virus therapeutic intervention strategies based on viral, vector and host factors involved in disease pathogenesis.

artículo científico

Desymmetrization Reactions of Indigo with Grignard Reagents for the Synthesis of Selective Antiplasmodial [1H,3'H]-3-Aryl-2,2'-diindol-3'-ones

scientific article published on 15 August 2019

Discovery of Potent Dual-Tailed Benzenesulfonamide Inhibitors of Human Carbonic Anhydrases Implicated in Glaucoma and in Vivo Profiling of Their Intraocular Pressure-Lowering Action

artículo científico publicado en 2020

Discovery of in silico hits targeting the nsP3 macro domain of chikungunya virus

artículo científico publicado en 2014

Diterpenoid alkaloids of Aconitum laciniatum and mitigation of inflammation by 14-O-acetylneoline in a murine model of ulcerative colitis. ⬇️

artículo científico publicado en 2015

Effects of methamphetamine and its primary human metabolite, p-hydroxymethamphetamine, on the development of the Australian blowfly Calliphora stygia

artículo científico publicado en 2014

Enantiopure Trans-4,5-Disubstituted 2-Imidazolidinones via Copper(I)-Catalyzed Ring Opening of 1,1'-DiBoc-2,2'-Biaziridine with Grignard Reagents

artículo científico publicado en 2015

Ethnobotanical authentication and identification of Khrog-sman (Lower Elevation Medicinal Plants) of Bhutan

artículo científico publicado en 2011

Evaluation of an ethnopharmacologically selected Bhutanese medicinal plants for their major classes of phytochemicals and biological activities.

artículo científico publicado en 2011

Facile Synthesis and Preliminary Structure-Activity Analysis of New Sulfonamides Against Trypanosoma brucei

artículo científico publicado en 2014

Fullerene Van der Waals Oligomers as Electron Traps

scientific article published on 24 July 2014

Further exploration of the heterocyclic diversity accessible from the allylation chemistry of indigo

artículo científico publicado en 2015

GC/GC-MS analysis, isolation and identification of bioactive essential oil components from the Bhutanese medicinal plant, Pleurospermum amabile

artículo científico publicado en 2013

Identification of chikungunya virus nsP2 protease inhibitors using structure-base approaches

artículo científico publicado en 2015

Inhibition of TNF-α production in LPS-activated THP-1 monocytic cells by the crude extracts of seven Bhutanese medicinal plants.

artículo científico publicado en 2013

Major Transitions in Cuticular Hydrocarbon Expression Coincide with Sexual Maturity in a Blowfly (Diptera: Calliphoridae)

scientific article published on 15 July 2020

Mining the Chemical Abstracts database with pharmacophore-based queries

artículo científico publicado en 2002

Molecular Docking Studies to Explore Potential Binding Pockets and Inhibitors for Chikungunya Virus Envelope Glycoproteins

artículo científico publicado en 2017

New anti-malarial compounds from database searching

artículo científico publicado en 2002

Novel pharmacophore-based methods reveal gossypol as a reverse transcriptase inhibitor

artículo científico publicado en 2003

Phenylpropanoids and furanocoumarins as antibacterial and antimalarial constituents of the Bhutanese medicinal plant Pleurospermum amabile.

artículo científico publicado en 2014

Photoprotection enhanced by red cell wall pigments in three East Antarctic mosses

artículo científico publicado en 2018

Phytochemical Studies on Two Australian Anigozanthos Plant Species

artículo científico publicado en 2017

Phytochemical and biological activity studies of the Bhutanese medicinal plant Corydalis crispa

artículo científico publicado el 1 de mayo de 2012

Phytochemical studies on the Australian native plant species Acacia pycnantha and Jacaranda mimosifolia D.Don

artículo científico publicado en 2018

Rapid cascade synthesis of poly-heterocyclic architectures from indigo

artículo científico publicado en 2013

Revealing indigenous Indonesian traditional medicine: anti-infective agents

artículo científico publicado el 1 de diciembre de 2011

Ring-opening and -expansion of 2,2'-biaziridine: access to diverse enantiopure linear and bicyclic vicinal diamines

artículo científico publicado en 2014

Structural reassignment of the mono- and bis-addition products from the addition reactions of N-(Diphenylmethylene)glycinate esters to [60]fullerene under Bingel conditions

artículo científico publicado en 2005

Structure based design towards the identification of novel binding sites and inhibitors for the chikungunya virus envelope proteins

artículo científico publicado en 2013

Synthesis and Density Functional Theory Studies of Azirinyl and Oxiranyl Functionalized Isoindigo and (3Z,3'Z)-3,3'-(ethane-1,2-diylidene)bis(indolin-2-one) Derivatives

artículo científico publicado en 2019

Synthesis and antibacterial activity of C2-symmetric binaphthyl scaffolded amino acid derivatives

scientific article published on 25 June 2011

Synthesis and antibacterial activity of some binaphthyl-supported macrocycles containing a cationic amino acid

artículo científico publicado en 2011

Synthesis and antibacterial studies of binaphthyl-based tripeptoids. Part 1.

artículo científico publicado en 2010

Synthesis and antibacterial studies of binaphthyl-based tripeptoids. Part 2.

artículo científico publicado en 2010

Synthesis and antimicrobial activity of binaphthyl-based, functionalized oxazole and thiazole peptidomimetics

artículo científico publicado en 2015

Synthesis and characterization of mono- and bis-methano[60]fullerenyl amino acid derivatives and their reductive ring-opening retro-bingel reactions.

artículo científico publicado en 2002

Synthesis and in vitro binding of N,N-dialkyl-2-phenylindol-3-yl-glyoxylamides for the peripheral benzodiazepine binding sites

artículo científico publicado en 2006

Synthesis and in vitro evaluation of tetrahydroisoquinolines with pendent aromatics as sigma-2 (σ2) selective ligands

artículo científico publicado en 2013

Synthesis of novel N-protected hydrophobic phenylalanines and their application in potential antibacterials.

artículo científico publicado en 2008

Synthesis of reaction-ready 6,6'-biindole and 6,6'-biisatin via palladium(II)-catalysed intramolecular C-H functionalisation

artículo científico publicado en 2010

Synthesis, molecular modeling and biological activity of methyl and thiomethyl substituted pyrimidines as corticotropin releasing hormone type 1 antagonists.

artículo científico publicado en 2003

The discovery of allyltyrosine based tripeptides as selective inhibitors of the HIV-1 integrase strand-transfer reaction.

artículo científico publicado en 2016

The first syntheses of enantiopure 2,2'-biindoline

artículo científico publicado en 2010

The medicinal chemistry of dengue fever

scientific article published on December 2009

The role of the HPA axis in psychiatric disorders and CRF antagonists as potential treatments.

artículo científico publicado en 2006

The synthesis and testing of arenearylpyrimidylmethanes as antimalarial agents

artículo científico publicado en 2006

Vascular Epiphytic Medicinal Plants as Sources of Therapeutic Agents: Their Ethnopharmacological Uses, Chemical Composition, and Biological Activities

scientific article published on 24 January 2020

Lista de obras de Paul A. Keller

A mild and general method for the synthesis of 5-substituted and 5,5-disubstituted fulleroprolines

A new methodology for the simulation of flexible protein-ligand interactions

A new protoberberine alkaloid from Meconopsis simplicifolia (D. Don) Walpers with potent antimalarial activity against a multidrug resistant Plasmodium falciparum strain

A twist of nature--the significance of atropisomers in biological systems

Alkaloids from the root of Indonesian Annona muricata L

An assessment of the Bhutanese traditional medicine for its ethnopharmacology, ethnobotany and ethnoquality: Textual understanding and the current practices

An improved synthesis of pyrido[2,3-d]pyrimidin-4(1H)-ones and their antimicrobial activity

Anilinopyrimidines as novel antituberculosis agents.

Antarctic Moss Biflavonoids Show High Antioxidant and Ultraviolet-Screening Activity

Anti-Infective and Anti-Cancer Properties of the Annona Species: Their Ethnomedicinal Uses, Alkaloid Diversity, and Pharmacological Activities

Anti-cancer Evaluation of Depsides Isolated from Indonesian Folious Lichens: Physcia millegrana, Parmelia dilatata and Parmelia aurulenta

Antimalarial alkaloids from a Bhutanese traditional medicinal plant Corydalis dubia

Atroposelective synthesis of axially chiral biaryl compounds

Binaphthyl scaffolded peptoids via ring-closing metathesis reactions and their anti-bacterial activities.

Binaphthyl-1,2,3-triazole peptidomimetics with activity against Clostridium difficile and other pathogenic bacteria.

Binaphthyl-anchored antibacterial tripeptide derivatives with hydrophobic C-terminal amino acid variations.

Binaphthyl-based dicationic peptoids with therapeutic potential.

Bioactive Discovery in the New Millennium--A Joint RACI, JMGM, FACS and MM2003 Conference. 5-9 February 2003, Lorne, Australia

Bioactive glycosides from the African medicinal plant Boerhavia erecta L.

Cascade reactions of indigo with oxiranes and aziridines: efficient access to dihydropyrazinodiindoles and spiro-oxazocinodiindoles

Cationic biaryl 1,2,3-triazolyl peptidomimetic amphiphiles targeting Clostridioides (Clostridium) difficile: Synthesis, antibacterial evaluation and an in vivo C. difficile infection model

Cationic biaryl 1,2,3-triazolyl peptidomimetic amphiphiles: synthesis, antibacterial evaluation and preliminary mechanism of action studies

Chikungunya virus: emerging targets and new opportunities for medicinal chemistry

Combining structure-based drug design and pharmacophores

Control of hepatitis C: a medicinal chemistry perspective

Current and Ongoing Developments in Targeting Clostridioides difficile Infection and Recurrence

Cyclic Phosphine Oxides and Phosphinamides from Di-Grignard Reagents and Phosphonic Dichlorides: Modular Access to Annulated Phospholanes

Dengue virus therapeutic intervention strategies based on viral, vector and host factors involved in disease pathogenesis.

Desymmetrization Reactions of Indigo with Grignard Reagents for the Synthesis of Selective Antiplasmodial [1H,3'H]-3-Aryl-2,2'-diindol-3'-ones

Discovery of Potent Dual-Tailed Benzenesulfonamide Inhibitors of Human Carbonic Anhydrases Implicated in Glaucoma and in Vivo Profiling of Their Intraocular Pressure-Lowering Action

Discovery of in silico hits targeting the nsP3 macro domain of chikungunya virus

Diterpenoid alkaloids of Aconitum laciniatum and mitigation of inflammation by 14-O-acetylneoline in a murine model of ulcerative colitis. ⬇️

Effects of methamphetamine and its primary human metabolite, p-hydroxymethamphetamine, on the development of the Australian blowfly Calliphora stygia

Enantiopure Trans-4,5-Disubstituted 2-Imidazolidinones via Copper(I)-Catalyzed Ring Opening of 1,1'-DiBoc-2,2'-Biaziridine with Grignard Reagents

Ethnobotanical authentication and identification of Khrog-sman (Lower Elevation Medicinal Plants) of Bhutan

Evaluation of an ethnopharmacologically selected Bhutanese medicinal plants for their major classes of phytochemicals and biological activities.

Facile Synthesis and Preliminary Structure-Activity Analysis of New Sulfonamides Against Trypanosoma brucei

Fullerene Van der Waals Oligomers as Electron Traps

Further exploration of the heterocyclic diversity accessible from the allylation chemistry of indigo

GC/GC-MS analysis, isolation and identification of bioactive essential oil components from the Bhutanese medicinal plant, Pleurospermum amabile

Identification of chikungunya virus nsP2 protease inhibitors using structure-base approaches

Inhibition of TNF-α production in LPS-activated THP-1 monocytic cells by the crude extracts of seven Bhutanese medicinal plants.

Major Transitions in Cuticular Hydrocarbon Expression Coincide with Sexual Maturity in a Blowfly (Diptera: Calliphoridae)

Mining the Chemical Abstracts database with pharmacophore-based queries

Molecular Docking Studies to Explore Potential Binding Pockets and Inhibitors for Chikungunya Virus Envelope Glycoproteins

New anti-malarial compounds from database searching

Novel pharmacophore-based methods reveal gossypol as a reverse transcriptase inhibitor

Phenylpropanoids and furanocoumarins as antibacterial and antimalarial constituents of the Bhutanese medicinal plant Pleurospermum amabile.

Photoprotection enhanced by red cell wall pigments in three East Antarctic mosses

Phytochemical Studies on Two Australian Anigozanthos Plant Species

Phytochemical and biological activity studies of the Bhutanese medicinal plant Corydalis crispa

Phytochemical studies on the Australian native plant species Acacia pycnantha and Jacaranda mimosifolia D.Don

Rapid cascade synthesis of poly-heterocyclic architectures from indigo

Revealing indigenous Indonesian traditional medicine: anti-infective agents

Ring-opening and -expansion of 2,2'-biaziridine: access to diverse enantiopure linear and bicyclic vicinal diamines

Structural reassignment of the mono- and bis-addition products from the addition reactions of N-(Diphenylmethylene)glycinate esters to [60]fullerene under Bingel conditions

Structure based design towards the identification of novel binding sites and inhibitors for the chikungunya virus envelope proteins

Synthesis and Density Functional Theory Studies of Azirinyl and Oxiranyl Functionalized Isoindigo and (3Z,3'Z)-3,3'-(ethane-1,2-diylidene)bis(indolin-2-one) Derivatives

Synthesis and antibacterial activity of C2-symmetric binaphthyl scaffolded amino acid derivatives

Synthesis and antibacterial activity of some binaphthyl-supported macrocycles containing a cationic amino acid

Synthesis and antibacterial studies of binaphthyl-based tripeptoids. Part 1.

Synthesis and antibacterial studies of binaphthyl-based tripeptoids. Part 2.

Synthesis and antimicrobial activity of binaphthyl-based, functionalized oxazole and thiazole peptidomimetics

Synthesis and characterization of mono- and bis-methano[60]fullerenyl amino acid derivatives and their reductive ring-opening retro-bingel reactions.

Synthesis and in vitro binding of N,N-dialkyl-2-phenylindol-3-yl-glyoxylamides for the peripheral benzodiazepine binding sites

Synthesis and in vitro evaluation of tetrahydroisoquinolines with pendent aromatics as sigma-2 (σ2) selective ligands

Synthesis of novel N-protected hydrophobic phenylalanines and their application in potential antibacterials.

Synthesis of reaction-ready 6,6'-biindole and 6,6'-biisatin via palladium(II)-catalysed intramolecular C-H functionalisation

Synthesis, molecular modeling and biological activity of methyl and thiomethyl substituted pyrimidines as corticotropin releasing hormone type 1 antagonists.

The discovery of allyltyrosine based tripeptides as selective inhibitors of the HIV-1 integrase strand-transfer reaction.

The first syntheses of enantiopure 2,2'-biindoline

The medicinal chemistry of dengue fever

The role of the HPA axis in psychiatric disorders and CRF antagonists as potential treatments.

The synthesis and testing of arenearylpyrimidylmethanes as antimalarial agents

Vascular Epiphytic Medicinal Plants as Sources of Therapeutic Agents: Their Ethnopharmacological Uses, Chemical Composition, and Biological Activities