Lista de obras - Antoni Riera - Dominio Público Uruguay

2-Piperidino-1,1,2-triphenylethanol: a highly effective catalyst for the enantioselective arylation of aldehydes.

artículo científico publicado en 2004

A tetradecapeptide somatostatin dicarba-analog: Synthesis, structural impact and biological activity.

artículo científico publicado en 2013

Addition of HOBt improves the conversion of thioester-Amine chemical ligation.

artículo científico publicado en 2015

Addition of diethylzinc to dicobalt hexacarbonyl complexes of alpha,beta-acetylenic aldehydes with virtually complete enantioselectivity. A formal synthesis of (+)-incrustoporin

scientific article published on 01 July 2002

Amino acids with fluorescent tetrazine ethers as bioorthogonal handles for peptide modification

artículo científico publicado en 2022

Asymmetric Approach to (+)-beta-Cuparenone by Intramolecular Pauson-Khand Reaction

artículo científico publicado en 1996

Asymmetric Pauson-Khand reactions using camphor-derived chelating thiols as chiral controllers.

artículo científico publicado en 2001

Asymmetric allylation/Pauson-Khand reaction: a simple entry to polycyclic amines. Application to the synthesis of aminosteroid analogues

artículo científico publicado en 2014

Asymmetric approach to Pauson-Khand bicyclization. Enantioselective formal synthesis of hirsutene

artículo científico publicado en 1990

Asymmetric intermolecular Pauson-Khand reaction of symmetrically substituted alkynes

artículo científico publicado en 2009

Asymmetric intermolecular cobalt-catalyzed Pauson-Khand reaction using a P-stereogenic bis-phosphane

artículo científico publicado en 2014

Borane as an efficient directing group. Stereoselective 1,2-addition of organometallic reagents to borane P-stereogenic N-phosphanylimines

artículo científico publicado en 2015

Boron trifluoride-induced, new stereospecific rearrangements of chiral epoxy ethers. Ready access to enantiopure 4-(diarylmethyl)-1,3-dioxolanes and 4,5-disubstituted tetrahydrobenzo[c]oxepin-4-ols

artículo científico publicado en 2006

Catalytic Regioselective Isomerization of 2,2-Disubstituted Oxetanes to Homoallylic Alcohols

artículo científico publicado en 2020

Dependency of colorectal cancer on a TGF-β-driven program in stromal cells for metastasis initiation

artículo científico publicado en 2012

Dialkylammonium tert-Butylmethylphosphinites: Stable Intermediates for the Synthesis of P-Stereogenic Ligands.

artículo científico publicado en 2017

Direct Asymmetric Hydrogenation of N-Methyl and N-Alkyl Imines with an Ir(III)H Catalyst

artículo científico publicado en 2018

EPI-001, A Compound Active against Castration-Resistant Prostate Cancer, Targets Transactivation Unit 5 of the Androgen Receptor

artículo científico publicado en 2016

Efficient Synthesis of Polycyclic γ-Lactams by Catalytic Carbonylation of Ene-Imines via Nickelacycle Intermediates

artículo científico publicado en 2017

Efficient stereoselective synthesis of 2-acetamido-1,2-dideoxyallonojirimycin (DAJNAc) and sp(2)-iminosugar conjugates: Novel hexosaminidase inhibitors with discrimination capabilities between the mature and precursor forms of the enzyme

artículo científico publicado en 2015

Enantioselective syntheses of carbanucleosides from the Pauson-Khand adduct of trimethylsilylacetylene and norbornadiene

scientific article published on 18 September 2008

Enantioselective synthesis of indolizidine alkaloid trans-209D.

artículo científico publicado en 2008

Enantioselective synthesis of sphingadienines and aromatic ceramide analogs

scientific article published on 02 September 2011

Enantioselective synthesis of trans-4-methylpipecolic acid

artículo científico publicado en 2007

Extending the Substrate Scope in the Hydrogenation of Unfunctionalized Tetrasubstituted Olefins with Ir-P Stereogenic Aminophosphine-Oxazoline Catalysts

scientific article published on 16 January 2019

Fine-tuning the π-π aromatic interactions in peptides: somatostatin analogues containing mesityl alanine.

artículo científico publicado en 2011

General approach to glycosidase inhibitors. Enantioselective synthesis of deoxymannojirimycin and swainsonine

artículo científico publicado en 2005

Half-sandwich complexes of Ir(iii), Rh(iii) and Ru(ii) with the MaxPhos ligand: metal centred chirality and cyclometallation

artículo científico publicado en 2017

Highly Enantioselective Iridium-Catalyzed Hydrogenation of 2-Aryl Allyl Phthalimides

scientific article published on 08 November 2019

Highly Enantioselective Iridium-Catalyzed Hydrogenation of Cyclic Enamides.

artículo científico publicado en 2016

Insights into structure-activity relationships of somatostatin analogs containing mesitylalanine.

artículo científico publicado en 2013

Intermolecular Pauson-Khand reactions of cyclopropene: a general synthesis of cyclopentanones

scientific article published on 01 October 2001

Iridium-Catalyzed Isomerization of N-Sulfonyl Aziridines to Allyl Amines

artículo científico publicado en 2018

Low-energy pathway for pauson-khand reactions: synthesis and reactivity of dicobalt hexacarbonyl complexes of chiral ynamines

scientific article published on 01 November 2000

Modular amino alcohol ligands containing bulky alkyl groups as chiral controllers for Et2Zn addition to aldehydes: illustration of a design principle.

artículo científico publicado en 2003

Molecular basis of the selective binding of MDMA enantiomers to the alpha4beta2 nicotinic receptor subtype: synthesis, pharmacological evaluation and mechanistic studies

artículo científico publicado en 2014

N-phosphino sulfinamide ligands: an efficient manner to combine sulfur chirality and phosphorus coordination behavior

artículo científico publicado en 2007

N-phosphino-p-tolylsulfinamide ligands: synthesis, stability, and application to the intermolecular Pauson-Khand reaction.

artículo científico publicado en 2008

New camphor-derived sulfur chiral controllers: Synthesis of (2R-exo)-10-methylthio-2-bornanethiol and (2R-exo)-2,10-bis(methylthio)bornane

New stereodivergent approach to 3-amino-2,3,6-trideoxysugars. Enantioselective synthesis of daunosamine, ristosamine, acosamine, and epi-daunosamine.

artículo científico publicado en 2003

P-Stereogenic Amino-Phosphines as Chiral Ligands: From Privileged Intermediates to Asymmetric Catalysis

artículo científico publicado en 2020

P-Stereogenic and Non-P-Stereogenic Ir-MaxPHOX in the Asymmetric Hydrogenation of N-Aryl Imines. Isolation and X-ray Analysis of Imine Iridacycles.

artículo científico publicado en 2018

P-Stereogenic bisphosphines with a hydrazine backbone: from N-N atropoisomerism to double nitrogen inversion.

artículo científico publicado en 2017

P-stereogenic secondary iminophosphorane ligands and their rhodium(I) complexes: taking advantage of NH/PH tautomerism

artículo científico publicado en 2012

Pauson-Khand adducts of N-Boc-propargylamine: a new approach to 4,5-disubstituted cyclopentenones

artículo científico publicado en 2013

Pauson-Khand reaction of internal dissymmetric trifluoromethyl alkynes. Influence of the alkene on the regioselectivity.

artículo científico publicado en 2014

Peptide aromatic interactions modulated by fluorinated residues: Synthesis, structure and biological activity of Somatostatin analogs containing 3-(3',5'difluorophenyl)-alanine

artículo científico publicado en 2016

Phosphine-alkene ligands as mechanistic probes in the Pauson-Khand reaction

artículo científico publicado en 2010

Phosphine-dependent stereoselectivity in the mitsunobu cyclodehydration of 1,2-diols: stereodivergent approach to triaryl-substituted epoxides

artículo científico publicado en 2007

Phosphine-substrate recognition through the C-H...O hydrogen bond: application to the asymmetric Pauson-Khand reaction

artículo científico publicado en 2005

Photochemical rearrangements of norbornadiene Pauson-Khand cycloadducts

scientific article published on 01 January 2007

Photochemistry of 3-substituted bicyclo[3.1.0]hex-3-en-2-ones. Regioselective synthesis of ortho-substituted phenols by Pauson-Khand reaction

artículo científico publicado en 2001

Polystyrene-supported (R)-2-piperazino-1,1,2-triphenylethanol: a readily available supported ligand with unparalleled catalytic activity and enantioselectivity.

artículo científico publicado en 2005

Primary and secondary aminophosphines as novel P-stereogenic building blocks for ligand synthesis

scientific article published on 01 December 2010

PuPHOS: a synthetically useful chiral bidentate ligand for the intermolecular Pauson-Khand reaction.

artículo científico publicado en 2004

Regioselectivity in intermolecular Pauson-Khand reactions of dissymmetric fluorinated alkynes.

artículo científico publicado en 2010

Regioselectivity of intermolecular Pauson-Khand reaction of aliphatic alkynes: experimental and theoretical study of the effect of alkyne polarization

artículo científico publicado en 2014

Ring-closing metathesis of chiral allylamines. Enantioselective synthesis of (2S,3R,4S)-3,4-dihydroxyproline.

artículo científico publicado en 2002

SSTR1- and SSTR3-Selective Somatostatin Analogues

artículo científico publicado en 2011

Solvent and substituent effects on the photochemistry of norbornadiene-diarylacetylene Pauson-Khand adducts

artículo científico publicado en 2011

Stereodivergent SN2@P Reactions of Borane Oxazaphospholidines: Experimental and Theoretical Studies

artículo científico publicado en 2013

Stereodivergent syntheses of conduramines and aminocyclitols.

artículo científico publicado en 2006

Stereoselective Synthesis of 2-Acetamido-1,2-dideoxyallonojirimycin (DAJNAc), a New Potent Hexosaminidase Inhibitor

artículo científico publicado en 2013

Stereoselective synthesis of 2-acetamido-1,2-dideoxynojirimycin (DNJNAc) and ureido-DNJNAc derivatives as new hexosaminidase inhibitors

artículo científico publicado en 2015

Stereoselective synthesis of P-stereogenic aminophosphines: ring opening of bulky oxazaphospholidines

artículo científico publicado en 2011

Stereospecific S(N)2@P reactions: novel access to bulky P-stereogenic ligands.

artículo científico publicado en 2015

Stromal gene expression defines poor-prognosis subtypes in colorectal cancer

artículo científico publicado en 2015

Structure of the N-terminal domain of the protein Expansion: an 'Expansion' to the Smad MH2 fold.

artículo científico publicado en 2015

Synthesis and Application of 3-Bromo-1,2,4,5-Tetrazine for Protein Labeling to Trigger Click-to-Release Biorthogonal Reactions

scientific article published on 26 February 2020

Synthesis and NMR experiments of (4,5,6-13C)-deoxymannojirimycin. A new entry to 13C-labeled glycosidase inhibitors

scientific article published on 29 April 2007

Synthesis and application of β-substituted Pauson-Khand adducts: trifluoromethyl as a removable steering group.

artículo científico publicado en 2013

Synthesis and coordination chemistry of enantiopure t-BuMeP(O)H.

artículo científico publicado en 2018

Synthesis of 3-alkyl-6-methyl-1,2,4,5-tetrazines via a Sonogashira-type cross-coupling reaction

scientific article published on 19 August 2020

Synthesis of heavily substituted 1,2-amino alcohols in enantiomerically pure form

artículo científico publicado en 2005

Synthesis of prostaglandin and phytoprostane B1 via regioselective intermolecular Pauson-Khand reactions

artículo científico publicado en 2009

Synthetic applications of chiral unsaturated epoxy alcohols prepared by sharpless asymmetric epoxidation.

artículo científico publicado en 2010

TGFβ drives immune evasion in genetically reconstituted colon cancer metastasis

artículo científico publicado en 2018

Tetramethylnorbornadiene, a versatile alkene for cyclopentenone synthesis through intermolecular Pauson-Khand reactions

artículo científico publicado en 2012

The Nuclear Receptor LXR Limits Bacterial Infection of Host Macrophages through a Mechanism that Impacts Cellular NAD Metabolism.

artículo científico publicado en 2017

The Pauson-Khand reaction of medium sized trans-cycloalkenes

artículo científico publicado en 2013

The conjugate addition-Peterson olefination reaction for the preparation of cross-conjugated cyclopentenone, PPAR-gamma ligands.

artículo científico publicado en 2008

Thermal and photochemical rearrangement of bicyclo[3.1.0]hex-3-en-2-one to the ketonic tautomer of phenol. Computational evidence for the formation of a diradical rather than a zwitterionic intermediate.

artículo científico publicado en 2002

Total Synthesis of ( R)-Sarkomycin Methyl Ester via Regioselective Intermolecular Pauson-Khand Reaction and Iridium-Catalyzed Asymmetric Isomerization

scientific article published on 15 June 2018

Lista de obras de Antoni Riera

2-Piperidino-1,1,2-triphenylethanol: a highly effective catalyst for the enantioselective arylation of aldehydes.

A tetradecapeptide somatostatin dicarba-analog: Synthesis, structural impact and biological activity.

Addition of HOBt improves the conversion of thioester-Amine chemical ligation.

Addition of diethylzinc to dicobalt hexacarbonyl complexes of alpha,beta-acetylenic aldehydes with virtually complete enantioselectivity. A formal synthesis of (+)-incrustoporin

Amino acids with fluorescent tetrazine ethers as bioorthogonal handles for peptide modification

Asymmetric Approach to (+)-beta-Cuparenone by Intramolecular Pauson-Khand Reaction

Asymmetric Pauson-Khand reactions using camphor-derived chelating thiols as chiral controllers.

Asymmetric allylation/Pauson-Khand reaction: a simple entry to polycyclic amines. Application to the synthesis of aminosteroid analogues

Asymmetric approach to Pauson-Khand bicyclization. Enantioselective formal synthesis of hirsutene

Asymmetric intermolecular Pauson-Khand reaction of symmetrically substituted alkynes

Asymmetric intermolecular cobalt-catalyzed Pauson-Khand reaction using a P-stereogenic bis-phosphane

Borane as an efficient directing group. Stereoselective 1,2-addition of organometallic reagents to borane P-stereogenic N-phosphanylimines

Boron trifluoride-induced, new stereospecific rearrangements of chiral epoxy ethers. Ready access to enantiopure 4-(diarylmethyl)-1,3-dioxolanes and 4,5-disubstituted tetrahydrobenzo[c]oxepin-4-ols

Catalytic Regioselective Isomerization of 2,2-Disubstituted Oxetanes to Homoallylic Alcohols

Dependency of colorectal cancer on a TGF-β-driven program in stromal cells for metastasis initiation

Dialkylammonium tert-Butylmethylphosphinites: Stable Intermediates for the Synthesis of P-Stereogenic Ligands.

Direct Asymmetric Hydrogenation of N-Methyl and N-Alkyl Imines with an Ir(III)H Catalyst

EPI-001, A Compound Active against Castration-Resistant Prostate Cancer, Targets Transactivation Unit 5 of the Androgen Receptor

Efficient Synthesis of Polycyclic γ-Lactams by Catalytic Carbonylation of Ene-Imines via Nickelacycle Intermediates

Efficient stereoselective synthesis of 2-acetamido-1,2-dideoxyallonojirimycin (DAJNAc) and sp(2)-iminosugar conjugates: Novel hexosaminidase inhibitors with discrimination capabilities between the mature and precursor forms of the enzyme

Enantioselective syntheses of carbanucleosides from the Pauson-Khand adduct of trimethylsilylacetylene and norbornadiene

Enantioselective synthesis of indolizidine alkaloid trans-209D.

Enantioselective synthesis of sphingadienines and aromatic ceramide analogs

Enantioselective synthesis of trans-4-methylpipecolic acid

Extending the Substrate Scope in the Hydrogenation of Unfunctionalized Tetrasubstituted Olefins with Ir-P Stereogenic Aminophosphine-Oxazoline Catalysts

Fine-tuning the π-π aromatic interactions in peptides: somatostatin analogues containing mesityl alanine.

General approach to glycosidase inhibitors. Enantioselective synthesis of deoxymannojirimycin and swainsonine

Half-sandwich complexes of Ir(iii), Rh(iii) and Ru(ii) with the MaxPhos ligand: metal centred chirality and cyclometallation

Highly Enantioselective Iridium-Catalyzed Hydrogenation of 2-Aryl Allyl Phthalimides

Highly Enantioselective Iridium-Catalyzed Hydrogenation of Cyclic Enamides.

Insights into structure-activity relationships of somatostatin analogs containing mesitylalanine.

Intermolecular Pauson-Khand reactions of cyclopropene: a general synthesis of cyclopentanones

Iridium-Catalyzed Isomerization of N-Sulfonyl Aziridines to Allyl Amines

Low-energy pathway for pauson-khand reactions: synthesis and reactivity of dicobalt hexacarbonyl complexes of chiral ynamines

Modular amino alcohol ligands containing bulky alkyl groups as chiral controllers for Et2Zn addition to aldehydes: illustration of a design principle.

Molecular basis of the selective binding of MDMA enantiomers to the alpha4beta2 nicotinic receptor subtype: synthesis, pharmacological evaluation and mechanistic studies

N-phosphino sulfinamide ligands: an efficient manner to combine sulfur chirality and phosphorus coordination behavior

N-phosphino-p-tolylsulfinamide ligands: synthesis, stability, and application to the intermolecular Pauson-Khand reaction.

New camphor-derived sulfur chiral controllers: Synthesis of (2R-exo)-10-methylthio-2-bornanethiol and (2R-exo)-2,10-bis(methylthio)bornane

New stereodivergent approach to 3-amino-2,3,6-trideoxysugars. Enantioselective synthesis of daunosamine, ristosamine, acosamine, and epi-daunosamine.

P-Stereogenic Amino-Phosphines as Chiral Ligands: From Privileged Intermediates to Asymmetric Catalysis

P-Stereogenic and Non-P-Stereogenic Ir-MaxPHOX in the Asymmetric Hydrogenation of N-Aryl Imines. Isolation and X-ray Analysis of Imine Iridacycles.

P-Stereogenic bisphosphines with a hydrazine backbone: from N-N atropoisomerism to double nitrogen inversion.

P-stereogenic secondary iminophosphorane ligands and their rhodium(I) complexes: taking advantage of NH/PH tautomerism

Pauson-Khand adducts of N-Boc-propargylamine: a new approach to 4,5-disubstituted cyclopentenones

Pauson-Khand reaction of internal dissymmetric trifluoromethyl alkynes. Influence of the alkene on the regioselectivity.

Peptide aromatic interactions modulated by fluorinated residues: Synthesis, structure and biological activity of Somatostatin analogs containing 3-(3',5'difluorophenyl)-alanine

Phosphine-alkene ligands as mechanistic probes in the Pauson-Khand reaction

Phosphine-dependent stereoselectivity in the mitsunobu cyclodehydration of 1,2-diols: stereodivergent approach to triaryl-substituted epoxides

Phosphine-substrate recognition through the C-H...O hydrogen bond: application to the asymmetric Pauson-Khand reaction

Photochemical rearrangements of norbornadiene Pauson-Khand cycloadducts

Photochemistry of 3-substituted bicyclo[3.1.0]hex-3-en-2-ones. Regioselective synthesis of ortho-substituted phenols by Pauson-Khand reaction

Polystyrene-supported (R)-2-piperazino-1,1,2-triphenylethanol: a readily available supported ligand with unparalleled catalytic activity and enantioselectivity.

Primary and secondary aminophosphines as novel P-stereogenic building blocks for ligand synthesis

PuPHOS: a synthetically useful chiral bidentate ligand for the intermolecular Pauson-Khand reaction.

Regioselectivity in intermolecular Pauson-Khand reactions of dissymmetric fluorinated alkynes.

Regioselectivity of intermolecular Pauson-Khand reaction of aliphatic alkynes: experimental and theoretical study of the effect of alkyne polarization

Ring-closing metathesis of chiral allylamines. Enantioselective synthesis of (2S,3R,4S)-3,4-dihydroxyproline.

SSTR1- and SSTR3-Selective Somatostatin Analogues

Solvent and substituent effects on the photochemistry of norbornadiene-diarylacetylene Pauson-Khand adducts

Stereodivergent SN2@P Reactions of Borane Oxazaphospholidines: Experimental and Theoretical Studies

Stereodivergent syntheses of conduramines and aminocyclitols.

Stereoselective Synthesis of 2-Acetamido-1,2-dideoxyallonojirimycin (DAJNAc), a New Potent Hexosaminidase Inhibitor

Stereoselective synthesis of 2-acetamido-1,2-dideoxynojirimycin (DNJNAc) and ureido-DNJNAc derivatives as new hexosaminidase inhibitors

Stereoselective synthesis of P-stereogenic aminophosphines: ring opening of bulky oxazaphospholidines

Stereospecific S(N)2@P reactions: novel access to bulky P-stereogenic ligands.

Stromal gene expression defines poor-prognosis subtypes in colorectal cancer

Structure of the N-terminal domain of the protein Expansion: an 'Expansion' to the Smad MH2 fold.

Synthesis and Application of 3-Bromo-1,2,4,5-Tetrazine for Protein Labeling to Trigger Click-to-Release Biorthogonal Reactions

Synthesis and NMR experiments of (4,5,6-13C)-deoxymannojirimycin. A new entry to 13C-labeled glycosidase inhibitors

Synthesis and application of β-substituted Pauson-Khand adducts: trifluoromethyl as a removable steering group.

Synthesis and coordination chemistry of enantiopure t-BuMeP(O)H.

Synthesis of 3-alkyl-6-methyl-1,2,4,5-tetrazines via a Sonogashira-type cross-coupling reaction

Synthesis of heavily substituted 1,2-amino alcohols in enantiomerically pure form

Synthesis of prostaglandin and phytoprostane B1 via regioselective intermolecular Pauson-Khand reactions

Synthetic applications of chiral unsaturated epoxy alcohols prepared by sharpless asymmetric epoxidation.

TGFβ drives immune evasion in genetically reconstituted colon cancer metastasis

Tetramethylnorbornadiene, a versatile alkene for cyclopentenone synthesis through intermolecular Pauson-Khand reactions

The Nuclear Receptor LXR Limits Bacterial Infection of Host Macrophages through a Mechanism that Impacts Cellular NAD Metabolism.