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Lista de obras de Donatella Taramelli

1-40 Beta-amyloid protein fragment modulates the expression of CD44 and CD71 on the astrocytoma cell line in the presence of IL1beta and TNFalpha.

artículo científico publicado en 2003

4-Alkyl- and 4-phenylcoumarins from Mesua ferrea as promising multidrug resistant antibacterials

artículo científico publicado en 2004

A Flow Cytometric Method for the Analysis of Phagocytosis and Killing by Polymorphonuclear Leukocytes

artículo científico publicado en 1997

A Plasmodium falciparum screening assay for anti-gametocyte drugs based on parasite lactate dehydrogenase detection

artículo científico publicado en 2013

A chemical susceptibility profile of the Plasmodium falciparum transmission stages by complementary cell-based gametocyte assays

artículo científico publicado en 2016

A chemotype that inhibits three unrelated pathogenic targets: the botulinum neurotoxin serotype A light chain, P. falciparum malaria, and the Ebola filovirus.

artículo científico publicado en 2011

A new class of antimalarial dioxanes obtained through a simple two-step synthetic approach: rational design and structure-activity relationship studies

artículo científico publicado en 2011

A rapid evaluation of phagocytosis and killing of Candida albicans by CD13+ leukocytes

artículo científico publicado en 1997

Activity against Plasmodium falciparum of cycloperoxide compounds obtained from the sponge Plakortis simplex.

artículo científico publicado en 2002

Altered Lipid Composition of Surfactant and Lung Tissue in Murine Experimental Malaria-Associated Acute Respiratory Distress Syndrome

artículo científico publicado en 2015

Amodiaquine analogues containing NO-donor substructures: synthesis and their preliminary evaluation as potential tools in the treatment of cerebral malaria

artículo científico publicado en 2011

Anti-plasmodial activity of Ailanthus excelsa.

artículo científico publicado en 2007

Anti-plasmodial and insecticidal activities of the essential oils of aromatic plants growing in the Mediterranean area

artículo científico publicado en 2012

Antimalarial agents against both sexual and asexual parasites stages: structure-activity relationships and biological studies of the Malaria Box compound 1-[5-(4-bromo-2-chlorophenyl)furan-2-yl]-N-[(piperidin-4-yl)methyl]methanamine (MMV019918) and a

scholarly article by Alessandra Vallone et al published 25 April 2018 in European Journal of Medicinal Chemistry

Antimalarial mannoxanes: hybrid antimalarial drugs with outstanding oral activity profiles and a potential dual mechanism of action

artículo científico publicado en 2011

Antimalarials based on the dioxane scaffold of plakortin. A concise synthesis and SAR studies

artículo científico publicado en 2010

Antiplasmodial activity of Punica granatum L. fruit rind

artículo científico publicado en 2009

Antiplasmodial and anti-inflammatory activities of Canthium henriquesianum (K. Schum), a plant used in traditional medicine in Burkina Faso

artículo científico publicado en 2013

Antiplasmodial triterpenoids from the fruits of neem, Azadirachta indica.

artículo científico publicado en 2010

Artemisinin Antimalarials Do Not Inhibit Hemozoin Formation

artículo científico publicado en 2003

Artemisinin and heme

artículo científico publicado en 2003

Atovaquone-statine "double-drugs" with high antiplasmodial activity.

artículo científico publicado en 2008

Autologous cellular immune response to primary and metastatic human melanomas and its regulation by DR antigens expressed on tumor cells

artículo científico publicado en 1985

CRIMALDDI: a co-ordinated, rational, and integrated effort to set logical priorities in anti-malarial drug discovery initiatives

artículo científico publicado en 2010

CRIMALDDI: platform technologies and novel anti-malarial drug targets

artículo científico publicado en 2013

Chloroquine enhances viral replication and murine disease.

artículo científico publicado en 2000

Clofazimine analogs with antileishmanial and antiplasmodial activity.

artículo científico publicado en 2014

Clotrimazole scaffold as an innovative pharmacophore towards potent antimalarial agents: design, synthesis, and biological and structure-activity relationship studies

artículo científico publicado en 2008

Combining 4-aminoquinoline- and clotrimazole-based pharmacophores toward innovative and potent hybrid antimalarials

artículo científico publicado en 2009

D-Glucose-Derived 1,2,4-Trioxepanes: Synthesis, Conformational Study, and Antimalarial Activity.

artículo científico publicado en 2015

Damicoside from Axinella damicornis: the influence of a glycosylated galactose 4-OH group on the immunostimulatory activity of alpha-galactoglycosphingolipids.

artículo científico publicado en 2005

Design and synthesis of potent antimalarial agents based on clotrimazole scaffold: exploring an innovative pharmacophore

artículo científico publicado en 2007

Design, synthesis, and structure-activity relationship studies of 4-quinolinyl- and 9-acrydinylhydrazones as potent antimalarial agents

artículo científico publicado en 2008

Development of piperazine-tethered heterodimers as potent antimalarials against chloroquine-resistant P. falciparum strains. Synthesis and molecular modeling

artículo científico publicado en 2007

Differential cytokine pattern in the spleens and livers of BALB/c mice infected with Penicillium marneffei: protective role of gamma interferon.

artículo científico publicado en 2003

Differential effects on angiogenesis of two antimalarial compounds, dihydroartemisinin and artemisone: implications for embryotoxicity

artículo científico publicado en 2007

Differential induction of malaria liver pathology in mice infected with Plasmodium chabaudi AS or Plasmodium berghei NK65.

artículo científico publicado en 2018

Dihydroartemisinin inhibits the human erythroid cell differentiation by altering the cell cycle

artículo científico publicado en 2012

Discovery and Pharmacophore Mapping of a Low-Nanomolar Inhibitor of P. falciparum Growth

artículo científico publicado en 2019

Does chloroquine really act through oxidative stress?

artículo científico publicado en 2002

Effects of iron on extracellular and intracellular growth of Penicillium marneffei.

artículo científico publicado en 2000

Ellagitannins of the fruit rind of pomegranate (Punica granatum) antagonize in vitro the host inflammatory response mechanisms involved in the onset of malaria

artículo científico publicado en 2010

Endoperoxide derivatives from marine organisms: 1,2-dioxanes of the plakortin family as novel antimalarial agents.

artículo científico publicado en 2006

Endoperoxide polyketides from a Chinese Plakortis simplex: Further evidence of the impact of stereochemistry on antimalarial activity of simple 1,2-dioxanes

article

Endotoxin requirement for macrophage activation by lymphokines in a rapid microcytotoxicity assay

scientific article published on 01 January 1980

Expression of normal histocompatibility antigens in murine lymphomas treated with 5-(3,3′-dimethyl-1-triazeno)-imidazole-4-carboxamide (DTIC) in vivo

artículo científico publicado en 1981

Facile Preparation of -Glycosylated 10-Piperazinyl Artemisinin Derivatives and Evaluation of Their Antimalarial and Cytotoxic Activities

Further optimization of plakortin pharmacophore: structurally simple 4-oxymethyl-1,2-dioxanes with promising antimalarial activity

artículo científico publicado en 2013

HaCaT Cells as a Reliable In Vitro Differentiation Model to Dissect the Inflammatory/Repair Response of Human Keratinocytes

artículo científico publicado en 2017

High antiplasmodial activity of novel plasmepsins I and II inhibitors.

artículo científico publicado en 2006

High-density lipoproteins attenuate interleukin-6 production in endothelial cells exposed to pro-inflammatory stimuli

article

Hypoxia modulates the effect of dihydroartemisinin on endothelial cells.

artículo científico publicado en 2011

Immune response to autologous human melanoma: implication of class I and II MHC products

artículo científico publicado en 1986

In Vivo and In Vitro Activities and ADME-Tox Profile of a Quinolizidine-Modified 4-Aminoquinoline: A Potent Anti-P. falciparum and Anti-P. vivax Blood-Stage Antimalarial

artículo científico publicado en 2017

In vitro Multistage Malaria Transmission Blocking Activity of Selected Malaria Box Compounds

scientific article published on 28 April 2020

In vitro activity of artemisone and artemisinin derivatives against extracellular and intracellular Helicobacter pylori

artículo científico publicado en 2016

In vitro activity of pharmacological compounds carried by lipidic microparticles

artículo científico publicado en 1992

In vitro studies on the mechanism of action of two compounds with antiplasmodial activity: ellagic acid and 3,4,5-trimethoxyphenyl(6'-O-aalloyl)-beta-D-glucopyranoside.

artículo científico publicado en 2003

Induction of immunotoxicity by polycyclic hydrocarbons: role of the Ah locus.

artículo científico publicado en 1984

Inhibition of VCAM-1 Expression in Endothelial Cells by Reconstituted High Density Lipoproteins

artículo científico publicado en 1997

Inhibition of intramacrophage growth of Penicillium marneffei by 4-aminoquinolines.

artículo científico publicado en 2001

Inhibition of metalloproteinase-9 secretion and gene expression by artemisinin derivatives

artículo científico publicado en 2014

Insights into the mechanism of action of ferroquine. Relationship between physicochemical properties and antiplasmodial activity.

artículo científico publicado en 2005

Interaction of artemisinins with oxyhemoglobin Hb-FeII, Hb-FeII, carboxyHb-FeII, heme-FeII, and carboxyheme FeII: significance for mode of action and implications for therapy of cerebral malaria

artículo científico publicado en 2009

Involvement of Nod2 in the innate immune response elicited by malarial pigment hemozoin

artículo científico publicado en 2014

Lack of suppressive activity of human primary melanoma cells on the activation of autologous lymphocytes

artículo científico publicado en 1988

Lymphokines inhibit macrophage RNA synthesis

artículo científico publicado en 1984

Lysis of autologous human melanoma cells by in vitro allosensitized peripheral blood lymphocytes

artículo científico publicado en 1982

Macrophage populations of different origins have distinct susceptibilities to lipid peroxidation induced by beta-haematin (malaria pigment).

artículo científico publicado en 1998

Malaria pigment stimulates chemokine production by human microvascular endothelium

artículo científico publicado en 2017

Manadoperoxides A-D from the Indonesian sponge Plakortis cfr. simplex. Further insights on the structure-activity relationships of simple 1,2-dioxane antimalarials

artículo científico publicado en 2010

Measurement of macrophage-mediated cytotoxicity against adherent and non-adherent target cells by release of 111indium-oxine

artículo científico publicado en 1981

Microsystem to Evaluate the Incorporation of3H-Uridine in Macrophage RNA

artículo científico publicado en 1981

Mimicking the intramolecular hydrogen bond: synthesis, biological evaluation, and molecular modeling of benzoxazines and quinazolines as potential antimalarial agents.

artículo científico publicado en 2012

Modified quaternary ammonium salts as potential antimalarial agents

artículo científico publicado en 2015

Modulation of glyceraldehyde 3 phosphate dehydrogenase activity and tyr-phosphorylation of Band 3 in human erythrocytes treated with ferriprotoporphyrin IX

artículo científico publicado en 2007

Natural haemozoin modulates matrix metalloproteinases and induces morphological changes in human microvascular endothelium

artículo científico publicado en 2011

Non-iron porphyrins inhibit beta-haematin (malaria pigment) polymerisation.

artículo científico publicado en 1997

Novel amodiaquine congeners as potent antimalarial agents

artículo científico publicado en 2008

Novel antimalarial aminoquinolines: heme binding and effects on normal or Plasmodium falciparum-parasitized human erythrocytes.

artículo científico publicado en 2009

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond

artículo científico publicado en 2016

Opening Opportunities for New Drugs Against Neglected Diseases

artículo científico publicado en 2008

Optimization of 4-aminoquinoline/clotrimazole-based hybrid antimalarials: further structure-activity relationships, in vivo studies, and preliminary toxicity profiling

artículo científico publicado en 2012

Oxidative stress and rheology in severe malaria

artículo científico publicado en 2003

Pathogenesis of malaria in tissues and blood.

artículo científico publicado en 2012

Phagocytosis of hemozoin (native and synthetic malaria pigment), and Plasmodium falciparum intraerythrocyte-stage parasites by human and mouse phagocytes

artículo científico publicado en 2000

Prevalence of pfcrt point mutations and level of chloroquine resistance in Plasmodium falciparum isolates from Africa

artículo científico publicado en 2005

Primary but not metastatic human melanomas expressing dr antigens stimulate autologous lymphocytes

scientific article published on 01 May 1984

Production of cytokines by alveolar and peritoneal macrophages stimulated byAspergillus fumigatusconidia or hyphae

scientific article published in 1996

Prooxidant activity of beta-hematin (synthetic malaria pigment) in arachidonic acid micelles and phospholipid large unilamellar vesicles

artículo científico publicado en 2001

RNA synthesis in activated macrophages I. Poly(I) · poly(C)-induced triggering of cytolytic activity is associated with decrease in RNA synthesis

artículo científico publicado en 1983

Regulation of human erythrocyte glyceraldehyde-3-phosphate dehydrogenase by ferriprotoporphyrin IX.

artículo científico publicado en 2005

Reinvestigating Old Pharmacophores: Are 4-Aminoquinolines and Tetraoxanes Potential Two-Stage Antimalarials?

artículo científico publicado en 2015

Role of Bacterial Lipopolysaccharide and Lymphokine in the Regulation of Macrophage Activation: Correlates between Secretion of Plasminogen Activator and Tumor Lysis

scientific article published on 01 May 1984

Safety of Artemisinin Derivatives in the First Trimester of Pregnancy: A Controversial Story

artículo científico publicado en 2020

Salinomycin and other ionophores as a new class of antimalarial drugs with transmission-blocking activity

artículo científico publicado en 2015

Selective toxicity of dihydroartemisinin on human CD34+ erythroid cell differentiation

artículo científico publicado el 3 de agosto de 2010

Spatial distribution of heme species in erythrocytes infected with Plasmodium falciparum by use of resonance Raman imaging and multivariate analysis

artículo científico publicado en 2008

Stability of the antimalarial drug dihydroartemisinin under physiologically relevant conditions: implications for clinical treatment and pharmacokinetic and in vitro assays

artículo científico publicado en 2015

Standardization of the physicochemical parameters to assess in vitro the beta-hematin inhibitory activity of antimalarial drugs.

artículo científico publicado en 2000

Suppression of lymphokine production: II. Macrophage-dependent inhibition of production of macrophage activating factor

article

Synthesis and Antiplasmodial Activity of Bicyclic Dioxanes as Simplified Dihydroplakortin Analogues

artículo científico publicado en 2011

Synthesis and Antiplasmodial Activity of Novel Chloroquine Analogues with Bulky Basic Side Chains

artículo científico publicado en 2015

Synthesis and antimalarial activities of some furoxan sulfones and related furazans.

artículo científico publicado en 2005

Synthesis and antiplasmodial activity of new heteroaryl derivatives of 7-chloro-4-aminoquinoline

artículo científico publicado en 2012

Synthesis of N1-arylidene-N2-quinolyl- and N2-acrydinylhydrazones as potent antimalarial agents active against CQ-resistant P. falciparum strains

artículo científico publicado en 2006

Synthesis, Molecular Docking and Antiplasmodial Activities of New Tetrahydro-β-Carbolines

artículo científico publicado en 2021

Synthesis, antimalarial activity, and cellular toxicity of new arylpyrrolylaminoquinolines

artículo científico publicado el 6 de agosto de 2010

Synthesis, antimalarial activity, and preclinical pharmacology of a novel series of 4'-fluoro and 4'-chloro analogues of amodiaquine. Identification of a suitable "back-up" compound for N-tert-butyl isoquine.

artículo científico publicado en 2009

Synthetic spirocyclic endoperoxides: new antimalarial scaffolds

Systemic administration of autologous, alloactivated helper-enriched lymphocytes to patients with metastatic melanoma of the lung. A phase I study.

artículo científico publicado en 1986

The Fe2+-mediated decomposition, PfATP6 binding, and antimalarial activities of artemisone and other artemisinins: the unlikelihood of C-centered radicals as bioactive intermediates

artículo científico publicado en 2007

The effect of synthetic malaria pigment (beta-haematin) on adhesion molecule expression and interleukin-6 production by human endothelial cells.

artículo científico publicado en 1998

The inhibition of lymphocyte stimulation by autologous human metastatic melanoma cells correlates with the expression of HLA-DR antigens on the tumor cells

artículo científico publicado en 1984

The lipid moiety of haemozoin (Malaria Pigment) and P. falciparum parasitised red blood cells bind synthetic and native endothelin-1

artículo científico publicado en 2010

The plant-based immunomodulator curcumin as a potential candidate for the development of an adjunctive therapy for cerebral malaria

artículo científico publicado en 2011

cAMP-Signalling Regulates Gametocyte-Infected Erythrocyte Deformability Required for Malaria Parasite Transmission

artículo científico publicado en 2015