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Lista de obras de Darren R Tyson

A Predictive Mathematical Modeling Approach for the Study of Doxorubicin Treatment in Triple Negative Breast Cancer

artículo científico publicado en 2017

A drift-diffusion checkpoint model predicts a highly variable and growth-factor-sensitive portion of the cell cycle G1 phase.

artículo científico publicado en 2018

Abstract 302: ECM/Integrin signaling promotes resistance to the combination of HER2 and PI3K inhibitors in HER2+, PIK3CA-mutant breast cancer

Altered TGF-α/β signaling drives cooperation between breast cancer cell populations.

artículo científico publicado en 2016

An in vitro model of tumor heterogeneity resolves genetic, epigenetic, and stochastic sources of cell state variability

artículo científico publicado en 2021

An unbiased metric of antiproliferative drug effect in vitro

artículo científico publicado en 2016

Annexin A2 positively contributes to the malignant phenotype and secretion of IL-6 in DU145 prostate cancer cells.

artículo científico publicado en 2009

Beyond genetics in personalized cancer treatment: assessing dynamics and heterogeneity of tumor responses.

artículo científico

Bone marrow stem cells for urologic tissue engineering

artículo científico publicado en 2008

Composite thin film and electrospun biomaterials for urologic tissue reconstruction

artículo científico publicado en 2011

Culture requirements of prostatic epithelial cell lines for acinar morphogenesis and lumen formation in vitro: role of extracellular calcium.

artículo científico publicado en 2007

Dependence On Glycolysis Sensitizes BRAF-mutated Melanomas For Increased Response To Targeted BRAF Inhibition.

artículo científico publicado en 2017

Extracellular Matrix/Integrin Signaling Promotes Resistance to Combined Inhibition of HER2 and PI3K in HER2+ Breast Cancer

artículo científico publicado en 2017

Fractional proliferation: a method to deconvolve cell population dynamics from single-cell data

artículo científico publicado en 2012

Human embryonic kidney cells (HEK-293 cells): characterization and dose-response relationship for modulated release of nerve growth factor for nerve regeneration.

artículo científico publicado en 2004

Increased osteoblastic c-fos expression by parathyroid hormone requires protein kinase A phosphorylation of the cyclic adenosine 3',5'-monophosphate response element-binding protein at serine 133.

artículo científico publicado en 1999

Induction of transcriptional activity of the cyclic adenosine monophosphate response element binding protein by parathyroid hormone and epidermal growth factor in osteoblastic cells.

artículo científico publicado en 2002

Inhibition of phosphodiesterase-4 (PDE4) activity triggers luminal apoptosis and AKT dephosphorylation in a 3-D colonic-crypt model.

artículo científico publicado en 2012

Long-term impact of a robot assisted laparoscopic prostatectomy mini fellowship training program on postgraduate urological practice patterns

artículo científico publicado en 2008

Loss of annexin A1 disrupts normal prostate glandular structure by inducing autocrine IL-6 signaling.

artículo científico publicado en 2009

Network Analysis of the Focal Adhesion to Invadopodia Transition Identifies a PI3K-PKCα Invasive Signaling Axis

artículo científico publicado el 11 de septiembre de 2012

Periprostatic adipose tissue as a modulator of prostate cancer aggressiveness

artículo científico publicado en 2009

Proteomics for the identification of new prostate cancer biomarkers

artículo científico publicado en 2006

Proteomics of cancer of hormone-dependent tissues.

artículo científico publicado en 2008

Quantifying heterogeneity and dynamics of clonal fitness in response to perturbation

artículo científico publicado en 2015

Response of head and neck squamous cell carcinoma cells carrying PIK3CA mutations to selected targeted therapies

artículo científico publicado en 2015

Role of GATA motifs in tissue factor pathway inhibitor gene expression in malignant cells.

artículo científico

Systems-level network modeling of Small Cell Lung Cancer subtypes identifies master regulators and destabilizers

scientific article published on 31 October 2019

The contribution of age structure to cell population responses to targeted therapeutics.

artículo científico publicado en 2012

The impact of altered annexin I protein levels on apoptosis and signal transduction pathways in prostate cancer cells.

artículo científico publicado en 2006

Trait variability of cancer cells quantified by high-content automated microscopy of single cells.

artículo científico publicado en 2009

Utilizing Three-Dimensional Culture Methods to Improve High-Throughput Drug Screening in Anaplastic Thyroid Carcinoma

artículo científico publicado en 2022