Lista de obras - Laurent Chaloin - Dominio Público Uruguay

A new peptide vector for efficient delivery of oligonucleotides into mammalian cells.

artículo científico

A new potent HIV-1 reverse transcriptase inhibitor. A synthetic peptide derived from the interface subunit domains

artículo científico publicado en 1999

Aggregates of an amphiphilic synthetic peptide bind and deliver all‐trans retinol and all‐trans retinoic acid into fibroblast cells ⬇️

artículo científico publicado el 15 de enero de 1998

Aminoglycoside binding and catalysis specificity of aminoglycoside 2″-phosphotransferase IVa: A thermodynamic, structural and kinetic study

artículo científico publicado en 2016

An evolutionary conserved zinc finger protein is involved in Toxoplasma gondii mRNA nuclear export.

artículo científico publicado en 2016

Analysis of Glycogen Synthase Kinase Inhibitors That Regulate Cytochrome P450 Expression in Primary Human Hepatocytes by Activation of β-Catenin, Aryl Hydrocarbon Receptor and Pregnane X Receptor Signaling.

artículo científico publicado en 2015

Beta-hydroxyphosphonate ribonucleoside analogues derived from 4-substituted-1,2,3-triazoles as IMP/GMP mimics: synthesis and biological evaluation.

artículo científico publicado en 2016

CD73 inhibition by purine cytotoxic nucleoside analogue-based diphosphonates

artículo científico publicado en 2018

Coarse-grained simulations of the HIV-1 matrix protein anchoring: revisiting its assembly on membrane domains

artículo científico publicado en 2014

Combination of a new generation of PNAs with a peptide-based carrier enables efficient targeting of cell cycle progression.

artículo científico publicado en 2004

Conformation and ion channel properties of a five-helix Bundle protein.

artículo científico publicado en 2001

Conformations of primary amphipathic carrier peptides in membrane mimicking environments.

artículo científico publicado en 1997

Design of carrier peptide-oligonucleotide conjugates with rapid membrane translocation and nuclear localization properties

artículo científico publicado en 1998

Differences in the transient kinetics of the binding of D-ADP and its mirror image L-ADP to human 3-phosphoglycerate kinase revealed by the presence of 3-phosphoglycerate.

artículo científico publicado en 2008

Effects on mollicutes (wall-less bacteria) of synthetic peptides comprising a signal peptide or a membrane fusion peptide, and a nuclear localization sequence (NLS) -- a comparison with melittin

artículo científico publicado en 1997

Electrostatic repulsion between HIV-1 capsid proteins modulates hexamer plasticity and in vitro assembly

artículo científico publicado en 2010

HIV-1 viral infectivity factor interacts with microtubule-associated protein light chain 3 and inhibits autophagy.

artículo científico publicado en 2015

Identification and characterization of inhibitors of cytoplasmic 5'-nucleotidase cN-II issued from virtual screening

artículo científico publicado en 2013

Identification of Noncompetitive Inhibitors of Cytosolic 5'-Nucleotidase II Using a Fragment-Based Approach

artículo científico publicado en 2015

Identification of allosteric inhibitors of the ecto-5'-nucleotidase (CD73) targeting the dimer interface.

artículo científico publicado en 2018

Improvement of Porphyrin Cellular Delivery and Activity by Conjugation to a Carrier Peptide

artículo científico publicado en 2001

Interaction of human 3-phosphoglycerate kinase with its two substrates: is substrate antagonism a kinetic advantage?

artículo científico publicado en 2011

Interactions of primary amphipathic vector peptides with membranes. Conformational consequences and influence on cellular localization

scientific article published on 01 April 1998

Ionic channels formed by a primary amphipathic peptide containing a signal peptide and a nuclear localization sequence

artículo científico publicado en 1998

Kinetic characterization and molecular docking of novel allosteric inhibitors of aminoglycoside phosphotransferases.

artículo científico publicado en 2016

Ligand chirality effects on the dynamics of human 3-phosphoglycerate kinase: comparison between D- and L-nucleotides.

artículo científico publicado en 2011

Lipid-induced organization of a primary amphipathic peptide: a coupled AFM-monolayer study

artículo científico publicado en 1999

Molecular basis for the lack of enantioselectivity of human 3-phosphoglycerate kinase

artículo científico publicado en 2008

Neurotoxicity of a Biopesticide Analog on Zebrafish Larvae at Nanomolar Concentrations

artículo científico publicado en 2016

Nouvelle stratégie pour vectorisation d'ARN dans des cellules de mammifères. Utilisation d'un vecteur peptidique

artículo científico publicado en 1997

Nucleotide promiscuity of 3-phosphoglycerate kinase is in focus: implications for the design of better anti-HIV analogues

artículo científico publicado en 2011

Potent inhibition of HIV-1 replication by backbone cyclic peptides bearing the Rev arginine rich motif

artículo científico

Regions 1.2 and 3.2 of the RNA Polymerase σ Subunit Promote DNA Melting and Attenuate Action of the Antibiotic Lipiarmycin.

artículo científico publicado en 2015

Restricted mobility of side chains on concave surfaces of solenoid proteins may impart heightened potential for intermolecular interactions

artículo científico publicado en 2015

Retroviral Envelope Glycoprotein Processing: Structural Investigation of the Cleavage Site ⬇️

artículo científico publicado el 31 de marzo de 1998

Retroviral envelope glycoprotein processing: structural investigation of the cleavage site

artículo científico publicado en 1998

Selectivity of kinases on the activation of tenofovir, an anti-HIV agent.

artículo científico publicado en 2012

Solid-phase synthesis and cellular localization of a C- and/or N-terminal labelled peptide

artículo científico publicado en 1996

Structural insights into the inhibition of cytosolic 5'-nucleotidase II (cN-II) by ribonucleoside 5'-monophosphate analogues

artículo científico publicado en 2011

Structure-activity relationships of β-hydroxyphosphonate nucleoside analogues as cytosolic 5'-nucleotidase II potential inhibitors: synthesis, in vitro evaluation and molecular modeling studies

artículo científico publicado en 2014

Substrate binding modifies the hinge bending characteristics of human 3-phosphoglycerate kinase: a molecular dynamics study.

artículo científico publicado en 2009

Synthesis of Substituted 5'-Aminoadenosine Derivatives and Evaluation of Their Inhibitory Potential toward CD73

scientific article published on 25 July 2019

Synthesis of a template-associated peptide designed as a transmembrane ion channel former

scientific article published on 01 September 1999

The Glutaminase-Dependent System Confers Extreme Acid Resistance to New Species and Atypical Strains of Brucella.

artículo científico publicado en 2017

The purine analog fludarabine acts as a cytosolic 5′-nucleotidase II inhibitor

artículo científico publicado en 2015

Therapeutic perspectives for cN-II in cancer.

artículo científico publicado en 2013

Transient kinetic studies reveal isomerization steps along the kinetic pathway of Thermus thermophilus 3-isopropylmalate dehydrogenase

artículo científico publicado en 2013

Translocating peptides and proteins and their use for gene delivery.

artículo científico publicado en 2000

Transportin-1 binds to the HIV-1 capsid via a nuclear localization signal and triggers uncoating

artículo científico publicado en 2019

VSV-G pseudotyping rescues HIV-1 CA mutations that impair core assembly or stability.

artículo científico publicado en 2008

Virus assembly and plasma membrane domains: which came first?

artículo científico

Lista de obras de Laurent Chaloin

A new peptide vector for efficient delivery of oligonucleotides into mammalian cells.

A new potent HIV-1 reverse transcriptase inhibitor. A synthetic peptide derived from the interface subunit domains

Aggregates of an amphiphilic synthetic peptide bind and deliver all‐trans retinol and all‐trans retinoic acid into fibroblast cells ⬇️

Aminoglycoside binding and catalysis specificity of aminoglycoside 2″-phosphotransferase IVa: A thermodynamic, structural and kinetic study

An evolutionary conserved zinc finger protein is involved in Toxoplasma gondii mRNA nuclear export.

Analysis of Glycogen Synthase Kinase Inhibitors That Regulate Cytochrome P450 Expression in Primary Human Hepatocytes by Activation of β-Catenin, Aryl Hydrocarbon Receptor and Pregnane X Receptor Signaling.

Beta-hydroxyphosphonate ribonucleoside analogues derived from 4-substituted-1,2,3-triazoles as IMP/GMP mimics: synthesis and biological evaluation.

CD73 inhibition by purine cytotoxic nucleoside analogue-based diphosphonates

Coarse-grained simulations of the HIV-1 matrix protein anchoring: revisiting its assembly on membrane domains

Combination of a new generation of PNAs with a peptide-based carrier enables efficient targeting of cell cycle progression.

Conformation and ion channel properties of a five-helix Bundle protein.

Conformations of primary amphipathic carrier peptides in membrane mimicking environments.

Design of carrier peptide-oligonucleotide conjugates with rapid membrane translocation and nuclear localization properties

Differences in the transient kinetics of the binding of D-ADP and its mirror image L-ADP to human 3-phosphoglycerate kinase revealed by the presence of 3-phosphoglycerate.

Effects on mollicutes (wall-less bacteria) of synthetic peptides comprising a signal peptide or a membrane fusion peptide, and a nuclear localization sequence (NLS) -- a comparison with melittin

Electrostatic repulsion between HIV-1 capsid proteins modulates hexamer plasticity and in vitro assembly

HIV-1 viral infectivity factor interacts with microtubule-associated protein light chain 3 and inhibits autophagy.

Identification and characterization of inhibitors of cytoplasmic 5'-nucleotidase cN-II issued from virtual screening

Identification of Noncompetitive Inhibitors of Cytosolic 5'-Nucleotidase II Using a Fragment-Based Approach

Identification of allosteric inhibitors of the ecto-5'-nucleotidase (CD73) targeting the dimer interface.

Improvement of Porphyrin Cellular Delivery and Activity by Conjugation to a Carrier Peptide

Interaction of human 3-phosphoglycerate kinase with its two substrates: is substrate antagonism a kinetic advantage?

Interactions of primary amphipathic vector peptides with membranes. Conformational consequences and influence on cellular localization

Ionic channels formed by a primary amphipathic peptide containing a signal peptide and a nuclear localization sequence

Kinetic characterization and molecular docking of novel allosteric inhibitors of aminoglycoside phosphotransferases.

Ligand chirality effects on the dynamics of human 3-phosphoglycerate kinase: comparison between D- and L-nucleotides.

Lipid-induced organization of a primary amphipathic peptide: a coupled AFM-monolayer study

Molecular basis for the lack of enantioselectivity of human 3-phosphoglycerate kinase

Neurotoxicity of a Biopesticide Analog on Zebrafish Larvae at Nanomolar Concentrations

Nouvelle stratégie pour vectorisation d'ARN dans des cellules de mammifères. Utilisation d'un vecteur peptidique

Nucleotide promiscuity of 3-phosphoglycerate kinase is in focus: implications for the design of better anti-HIV analogues

Potent inhibition of HIV-1 replication by backbone cyclic peptides bearing the Rev arginine rich motif

Regions 1.2 and 3.2 of the RNA Polymerase σ Subunit Promote DNA Melting and Attenuate Action of the Antibiotic Lipiarmycin.

Restricted mobility of side chains on concave surfaces of solenoid proteins may impart heightened potential for intermolecular interactions

Retroviral Envelope Glycoprotein Processing: Structural Investigation of the Cleavage Site ⬇️

Retroviral envelope glycoprotein processing: structural investigation of the cleavage site

Selectivity of kinases on the activation of tenofovir, an anti-HIV agent.

Solid-phase synthesis and cellular localization of a C- and/or N-terminal labelled peptide

Structural insights into the inhibition of cytosolic 5'-nucleotidase II (cN-II) by ribonucleoside 5'-monophosphate analogues

Structure-activity relationships of β-hydroxyphosphonate nucleoside analogues as cytosolic 5'-nucleotidase II potential inhibitors: synthesis, in vitro evaluation and molecular modeling studies

Substrate binding modifies the hinge bending characteristics of human 3-phosphoglycerate kinase: a molecular dynamics study.

Synthesis of Substituted 5'-Aminoadenosine Derivatives and Evaluation of Their Inhibitory Potential toward CD73

Synthesis of a template-associated peptide designed as a transmembrane ion channel former

The Glutaminase-Dependent System Confers Extreme Acid Resistance to New Species and Atypical Strains of Brucella.

The purine analog fludarabine acts as a cytosolic 5′-nucleotidase II inhibitor

Therapeutic perspectives for cN-II in cancer.

Transient kinetic studies reveal isomerization steps along the kinetic pathway of Thermus thermophilus 3-isopropylmalate dehydrogenase

Translocating peptides and proteins and their use for gene delivery.

Transportin-1 binds to the HIV-1 capsid via a nuclear localization signal and triggers uncoating

VSV-G pseudotyping rescues HIV-1 CA mutations that impair core assembly or stability.

Virus assembly and plasma membrane domains: which came first?