Lista de obras - Lars Henning Engelholm - Dominio Público Uruguay

A composite role of vitronectin and urokinase in the modulation of cell morphology upon expression of the urokinase receptor

artículo científico publicado en 2008

A supra-cellular model for coupling of bone resorption to formation during remodeling: lessons from two bone resorption inhibitors affecting bone formation differently

artículo científico publicado en 2013

A urokinase receptor-associated protein with specific collagen binding properties

artículo científico publicado en 2000

Advances in targeted delivery of small interfering RNA using simple bioconjugates

artículo científico

C4.4A gene ablation is compatible with normal epidermal development and causes modest overt phenotypes

artículo científico publicado en 2016

CRISPR/Cas9 Engineering of Adult Mouse Liver Demonstrates That the Dnajb1-Prkaca Gene Fusion Is Sufficient to Induce Tumors Resembling Fibrolamellar Hepatocellular Carcinoma.

artículo científico publicado en 2017

Collagen density regulates the activity of tumor-infiltrating T cells

artículo científico publicado en 2019

Complementary roles of intracellular and pericellular collagen degradation pathways in vivo.

artículo científico publicado en 2007

Complex determinants in specific members of the mannose receptor family govern collagen endocytosis

artículo científico publicado en 2014

Conformational regulation of urokinase receptor function: impact of receptor occupancy and epitope-mapped monoclonal antibodies on lamellipodia induction.

artículo científico publicado en 2011

Crystal structures of the ligand-binding region of uPARAP: effect of calcium ion binding

artículo científico publicado en 2016

Differential actions of the endocytic collagen receptor uPARAP/Endo180 and the collagenase MMP-2 in bone homeostasis

artículo científico publicado en 2013

Differential binding of urokinase and peptide antagonists to the urokinase receptor: evidence from characterization of the receptor in four primate species

artículo científico publicado en 2001

Differential gene expression in human mammary carcinoma cells: identification of a new member of a receptor family.

artículo científico publicado en 1997

Dimerization of endogenous MT1-MMP is a regulatory step in the activation of the 72-kDa gelatinase MMP-2 on fibroblasts and fibrosarcoma cells

artículo científico publicado en 2008

Early reversal cells in adult human bone remodeling: osteoblastic nature, catabolic functions and interactions with osteoclasts.

artículo científico publicado en 2016

Endocytic collagen degradation: a novel mechanism involved in protection against liver fibrosis

artículo científico publicado en 2012

Extracellular collagenases and the endocytic receptor, urokinase plasminogen activator receptor-associated protein/Endo180, cooperate in fibroblast-mediated collagen degradation

artículo científico publicado en 2007

Fibroblast growth factor receptor 4 regulates tumor invasion by coupling fibroblast growth factor signaling to extracellular matrix degradation

artículo científico publicado en 2010

Gender affects skin wound healing in plasminogen deficient mice

artículo científico publicado en 2013

Identification of two estrogen regulated genes associated with growth regulation of human breast cancer.

artículo científico publicado en 2001

Immune regulation by fibroblasts in tissue injury depends on uPARAP-mediated uptake of collectins

artículo científico publicado en 2018

Increased Expression of the Collagen Internalization Receptor uPARAP/Endo180 in the Stroma of Head and Neck Cancer

artículo científico publicado en 2006

Inflammation and uPAR-Expression in Colorectal Liver Metastases in Relation to Growth Pattern and Neo-adjuvant Therapy.

artículo científico publicado en 2015

Inhibitory Monoclonal Antibodies against Mouse Proteases Raised in Gene-Deficient Mice Block Proteolytic Functions in vivo ⬇️

artículo científico publicado el 28 de junio de 2012

Loss of miR-10a activates lpo and collaborates with activated Wnt signaling in inducing intestinal neoplasia in female mice

artículo científico publicado en 2013

M2-like macrophages are responsible for collagen degradation through a mannose receptor-mediated pathway

artículo científico publicado en 2013

MT1-MMP and type II collagen specify skeletal stem cells and their bone and cartilage progeny.

artículo científico publicado en 2009

Mesenchymal cells reactivate Snail1 expression to drive three-dimensional invasion programs

artículo científico publicado en 2009

Monitoring mammary tumor progression and effect of tamoxifen treatment in MMTV-PymT using MRI and magnetic resonance spectroscopy with hyperpolarized [1-13C]pyruvate

artículo científico publicado en 2014

No effect of NGAL/lipocalin-2 on aggressiveness of cancer in the MMTV-PyMT/FVB/N mouse model for breast cancer

artículo científico publicado en 2012

Personalized B cell response to the <i>Lactobacillus rhamnosus GG</i> probiotic in healthy human subjects: a randomized trial

artículo científico publicado en 2020

Phagocytosis of Collagen Fibrils by Fibroblasts In Vivo Is Independent of the uPARAP/Endo180 Receptor.

artículo científico publicado en 2016

Plasmin-driven fibrinolysis facilitates skin tumor growth in a gender-dependent manner.

artículo científico publicado en 2012

Quantification of tissue inhibitor of metalloproteinases 2 in plasma from healthy donors and cancer patients.

artículo científico publicado en 2005

Targeting a novel bone degradation pathway in primary bone cancer by inactivation of the collagen receptor uPARAP/Endo180

Targeting a single function of the multifunctional matrix metalloprotease MT1-MMP: impact on lymphangiogenesis

artículo científico publicado en 2013

The collagen receptor uPARAP/Endo180 as a novel target for antibody-drug conjugate mediated treatment of mesenchymal and leukemic cancers.

artículo científico publicado en 2017

The collagen receptor uPARAP/Endo180 in tissue degradation and cancer (Review)

artículo científico publicado en 2015

The collagen receptor uPARAP/Endo180.

artículo científico publicado en 2009

The focal adhesion-associated proteins DOCK5 and GIT2 comprise a rheostat in control of epithelial invasion.

artículo científico publicado en 2016

The non-phagocytic route of collagen uptake: a distinct degradation pathway

artículo científico publicado en 2011

The number of regulatory T cells in transbronchial lung allograft biopsies is related to FoxP3 mRNA levels in bronchoalveolar lavage fluid and to the degree of acute cellular rejection ⬇️

artículo científico publicado el 19 de agosto de 2013

Tumor MMP-1 activates endothelial PAR1 to facilitate vascular intravasation and metastatic dissemination

artículo científico publicado en 2013

Urokinase receptor-associated protein (uPARAP) is expressed in connection with malignant as well as benign lesions of the human breast and occurs in specific populations of stromal cells

artículo científico publicado en 2002

uPARAP/Endo180 is essential for cellular uptake of collagen and promotes fibroblast collagen adhesion

artículo científico publicado en 2003

uPARAP/Endo180 receptor is a gatekeeper of VEGFR-2/VEGFR-3 heterodimerisation during pathological lymphangiogenesis

scientific article published in Nature Communications

uPARAP/endo180 directs lysosomal delivery and degradation of collagen IV.

artículo científico publicado en 2004

Lista de obras de Lars Henning Engelholm

A composite role of vitronectin and urokinase in the modulation of cell morphology upon expression of the urokinase receptor

A supra-cellular model for coupling of bone resorption to formation during remodeling: lessons from two bone resorption inhibitors affecting bone formation differently

A urokinase receptor-associated protein with specific collagen binding properties

Advances in targeted delivery of small interfering RNA using simple bioconjugates

C4.4A gene ablation is compatible with normal epidermal development and causes modest overt phenotypes

CRISPR/Cas9 Engineering of Adult Mouse Liver Demonstrates That the Dnajb1-Prkaca Gene Fusion Is Sufficient to Induce Tumors Resembling Fibrolamellar Hepatocellular Carcinoma.

Collagen density regulates the activity of tumor-infiltrating T cells

Complementary roles of intracellular and pericellular collagen degradation pathways in vivo.

Complex determinants in specific members of the mannose receptor family govern collagen endocytosis

Conformational regulation of urokinase receptor function: impact of receptor occupancy and epitope-mapped monoclonal antibodies on lamellipodia induction.

Crystal structures of the ligand-binding region of uPARAP: effect of calcium ion binding

Differential actions of the endocytic collagen receptor uPARAP/Endo180 and the collagenase MMP-2 in bone homeostasis

Differential binding of urokinase and peptide antagonists to the urokinase receptor: evidence from characterization of the receptor in four primate species

Differential gene expression in human mammary carcinoma cells: identification of a new member of a receptor family.

Dimerization of endogenous MT1-MMP is a regulatory step in the activation of the 72-kDa gelatinase MMP-2 on fibroblasts and fibrosarcoma cells

Early reversal cells in adult human bone remodeling: osteoblastic nature, catabolic functions and interactions with osteoclasts.

Endocytic collagen degradation: a novel mechanism involved in protection against liver fibrosis

Extracellular collagenases and the endocytic receptor, urokinase plasminogen activator receptor-associated protein/Endo180, cooperate in fibroblast-mediated collagen degradation

Fibroblast growth factor receptor 4 regulates tumor invasion by coupling fibroblast growth factor signaling to extracellular matrix degradation

Gender affects skin wound healing in plasminogen deficient mice

Identification of two estrogen regulated genes associated with growth regulation of human breast cancer.

Immune regulation by fibroblasts in tissue injury depends on uPARAP-mediated uptake of collectins

Increased Expression of the Collagen Internalization Receptor uPARAP/Endo180 in the Stroma of Head and Neck Cancer

Inflammation and uPAR-Expression in Colorectal Liver Metastases in Relation to Growth Pattern and Neo-adjuvant Therapy.

Inhibitory Monoclonal Antibodies against Mouse Proteases Raised in Gene-Deficient Mice Block Proteolytic Functions in vivo ⬇️

Loss of miR-10a activates lpo and collaborates with activated Wnt signaling in inducing intestinal neoplasia in female mice

M2-like macrophages are responsible for collagen degradation through a mannose receptor-mediated pathway

MT1-MMP and type II collagen specify skeletal stem cells and their bone and cartilage progeny.

Mesenchymal cells reactivate Snail1 expression to drive three-dimensional invasion programs

Monitoring mammary tumor progression and effect of tamoxifen treatment in MMTV-PymT using MRI and magnetic resonance spectroscopy with hyperpolarized [1-13C]pyruvate

No effect of NGAL/lipocalin-2 on aggressiveness of cancer in the MMTV-PyMT/FVB/N mouse model for breast cancer

Personalized B cell response to the <i>Lactobacillus rhamnosus GG</i> probiotic in healthy human subjects: a randomized trial

Phagocytosis of Collagen Fibrils by Fibroblasts In Vivo Is Independent of the uPARAP/Endo180 Receptor.

Plasmin-driven fibrinolysis facilitates skin tumor growth in a gender-dependent manner.

Quantification of tissue inhibitor of metalloproteinases 2 in plasma from healthy donors and cancer patients.

Targeting a novel bone degradation pathway in primary bone cancer by inactivation of the collagen receptor uPARAP/Endo180

Targeting a single function of the multifunctional matrix metalloprotease MT1-MMP: impact on lymphangiogenesis

The collagen receptor uPARAP/Endo180 as a novel target for antibody-drug conjugate mediated treatment of mesenchymal and leukemic cancers.

The collagen receptor uPARAP/Endo180 in tissue degradation and cancer (Review)

The collagen receptor uPARAP/Endo180.

The focal adhesion-associated proteins DOCK5 and GIT2 comprise a rheostat in control of epithelial invasion.

The non-phagocytic route of collagen uptake: a distinct degradation pathway

The number of regulatory T cells in transbronchial lung allograft biopsies is related to FoxP3 mRNA levels in bronchoalveolar lavage fluid and to the degree of acute cellular rejection ⬇️

Tumor MMP-1 activates endothelial PAR1 to facilitate vascular intravasation and metastatic dissemination

Urokinase receptor-associated protein (uPARAP) is expressed in connection with malignant as well as benign lesions of the human breast and occurs in specific populations of stromal cells

uPARAP/Endo180 is essential for cellular uptake of collagen and promotes fibroblast collagen adhesion

uPARAP/Endo180 receptor is a gatekeeper of VEGFR-2/VEGFR-3 heterodimerisation during pathological lymphangiogenesis

uPARAP/endo180 directs lysosomal delivery and degradation of collagen IV.