Lista de obras - Terry J. Smith - Dominio Público Uruguay

A novel ELISpot method for adherent cells

artículo científico publicado en 2004

A population-based prospective study of optic neuritis

artículo científico publicado en 2017

Activation of human orbital fibroblasts through CD40 engagement results in a dramatic induction of hyaluronan synthesis and prostaglandin endoperoxide H synthase-2 expression. Insights into potential pathogenic mechanisms of thyroid-associated ophth

artículo científico publicado en 1998

Advances in understanding autoimmune pituitary disease: standardized methods for autoantibody detection

artículo científico publicado en 2014

Assessment of rapid morphological changes associated with elevated cAMP levels in human orbital fibroblasts

artículo científico publicado en 1998

B cell depletion in Graves' disease: the right answer to the wrong question?

artículo científico publicado en 2007

Bidimensional gel electrophoretic analysis of protein synthesis and response to interferon-gamma in cultured human dermal fibroblasts

scientific article published on 01 June 1993

Building the Case for Insulin-Like Growth Factor Receptor-I Involvement in Thyroid-Associated Ophthalmopathy.

artículo científico publicado en 2016

CD34- Orbital Fibroblasts From Patients With Thyroid-Associated Ophthalmopathy Modulate TNF-α Expression in CD34+ Fibroblasts and Fibrocytes.

artículo científico publicado en 2018

CD40 Expression in Fibrocytes Is Induced by TSH: Potential Synergistic Immune Activation

artículo científico publicado en 2016

Cerebrospinal fluid biomarkers for predicting development of multiple sclerosis in acute optic neuritis: a population-based prospective cohort study

article

Challenges in Orphan Drug Development: Identification of Effective Therapy for Thyroid-Associated Ophthalmopathy

article

Characterization of Regulatory B Cells in Graves' Disease and Hashimoto's Thyroiditis

artículo científico publicado en 2015

Characterization of the anaemia associated with Graves' disease

artículo científico publicado en 2008

Circulating mononuclear cells from euthyroid patients with thyroid-associated ophthalmopathy exhibit characteristic phenotypes.

artículo científico publicado en 2007

Collaborative International Research in Clinical and Longitudinal Experience Study in NMOSD

scientific article published on 28 June 2019

Current concepts in the molecular pathogenesis of thyroid-associated ophthalmopathy.

artículo científico publicado en 2014

Current perspective on the pathogenesis of Graves' disease and ophthalmopathy.

artículo científico publicado en 2003

Cyclooxygenases as the principal targets for the actions of NSAIDs

scientific article published on 01 August 1998

Cytokine-induced lymphocyte chemoattraction from cultured human thyrocytes: evidence for interleukin-16 and regulated upon activation, normal T cell expressed, and secreted expression

artículo científico publicado en 2003

Cytokines are both villains and potential therapeutic targets in thyroid-associated ophthalmopathy: From bench to bedside.

artículo científico publicado en 2014

Cytokines, Graves' disease, and thyroid-associated ophthalmopathy

artículo científico publicado en 2008

Cytoplasmic prostaglandin E2 synthase is dominantly expressed in cultured KAT-50 thyrocytes, cells that express constitutive prostaglandin-endoperoxide H synthase-2. Basis for low protaglandin E2 production.

artículo científico publicado en 2002

Development of criteria for evaluating clinical response in thyroid eye disease using a modified Delphi technique

artículo científico publicado en 2009

Divergent Sp1 protein levels may underlie differential expression of UDP-glucose dehydrogenase by fibroblasts: role in susceptibility to orbital Graves disease.

artículo científico publicado en 2011

Divergent expression of IL-1 receptor antagonists in CD34⁺ fibrocytes and orbital fibroblasts in thyroid-associated ophthalmopathy: contribution of fibrocytes to orbital inflammation

artículo científico publicado en 2013

Evidence of adipocyte differentiation in human orbital fibroblasts in primary culture

artículo científico publicado en 1996

Expression of thyrotropin receptor, thyroglobulin, sodium-iodide symporter, and thyroperoxidase by fibrocytes depends on AIRE.

artículo científico publicado en 2014

Fibroblasts as sentinel cells: role of the CDcd40-CDcd40 ligand system in fibroblast activation and lung inflammation and fibrosis

artículo científico publicado en 2001

Fibroblasts expressing the thyrotropin receptor overarch thyroid and orbit in Graves' disease.

artículo científico publicado en 2011

Glucocorticoid regulation of glycosaminoglycan synthesis in cultured human skin fibroblasts: evidence for a receptor-mediated mechanism involving effects on specific de novo protein synthesis

scientific article published on 01 February 1988

Glucocorticoids enhance glucose uptake and affect differentiation and beta-adrenergic responsiveness in muscle cell cultures ⬇️

artículo científico publicado el 1 de marzo de 1981

Graves' Disease

artículo científico publicado en 2017

Graves' Disease.

artículo científico publicado en 2016

HIF2A-LOX pathway promotes fibrotic tissue remodeling in thyroid-associated orbitopathy

artículo científico publicado en 2019

Histopathology of brow fat in thyroid-associated orbitopathy.

artículo científico publicado en 2012

Human fibrocytes express multiple antigens associated with autoimmune endocrine diseases

artículo científico publicado en 2014

Hyaluronan accumulation in thyroid tissue: evidence for contributions from epithelial cells and fibroblasts.

artículo científico publicado en 2006

IGF-I receptor and thyroid-associated ophthalmopathy

artículo científico publicado en 2017

Immune mechanisms in thyroid eye disease.

artículo científico publicado en 2008

Immunoglobulin G from patients with Graves' disease induces interleukin-16 and RANTES expression in cultured human thyrocytes: a putative mechanism for T-cell infiltration of the thyroid in autoimmune disease.

artículo científico publicado en 2006

Immunoglobulins from patients with Graves' disease induce hyaluronan synthesis in their orbital fibroblasts through the self-antigen, insulin-like growth factor-I receptor.

artículo científico publicado en 2004

Immunopathogenesis of thyroid eye disease: emerging paradigms

artículo científico publicado en 2010

Inclusion of brain volume loss in a revised measure of 'no evidence of disease activity' (NEDA-4) in relapsing-remitting multiple sclerosis

artículo científico publicado en 2015

Increased expression of TSH receptor by fibrocytes in thyroid-associated ophthalmopathy leads to chemokine production.

artículo científico publicado en 2012

Increased generation of fibrocytes in thyroid-associated ophthalmopathy

artículo científico publicado en 2009

Induction of heme oxygenase mRNA by cobalt protoporphyrin in rat liver

artículo científico publicado en 1991

Insights into the role of fibroblasts in human autoimmune diseases.

artículo científico publicado en 2005

Insulin-like Growth Factor-I Receptor and Thyroid-Associated Ophthalmopathy

scientific article published on 01 February 2019

Integrative continuum: accelerating therapeutic advances in rare autoimmune diseases

artículo científico

Interleukin-4 induces 15-lipoxygenase-1 expression in human orbital fibroblasts from patients with Graves disease. Evidence for anatomic site-selective actions of Th2 cytokines.

artículo científico publicado en 2006

Interleukin-6 production in CD40-engaged fibrocytes in thyroid-associated ophthalmopathy: involvement of Akt and NF-κB.

artículo científico publicado en 2012

Is IGF-I receptor a target for autoantibody generation in Graves' disease?

artículo científico publicado en 2013

Leukoregulin induction of protein expression in human orbital fibroblasts: evidence for anatomical site-restricted cytokine-target cell interactions.

artículo científico publicado en 1998

Magnetic resonance imaging findings at the first episode of acute optic neuritis

artículo científico publicado en 2017

Molecular pathology of Muller's muscle in Graves' ophthalmopathy.

artículo científico publicado en 2005

Neuromyelitis optica spectrum disorder: Patient experience and quality of life

scientific article published on 20 June 2019

New advances in understanding thyroid-associated ophthalmopathy and the potential role for insulin-like growth factor-I receptor.

artículo científico publicado en 2018

Orbital fibroblasts from patients with thyroid-associated ophthalmopathy overexpress CD40: CD154 hyperinduces IL-6, IL-8, and MCP-1.

scientific article published on 30 December 2008

PGE2 induces IL-6 in orbital fibroblasts through EP2 receptors and increased gene promoter activity: implications to thyroid-associated ophthalmopathy

artículo científico publicado en 2010

PI3K/AKT pathway mediates induction of IL-1RA by TSH in fibrocytes: modulation by PTEN

artículo científico publicado en 2014

Pharmacotherapy: does selenium supplementation improve Graves ophthalmopathy?

artículo científico publicado en 2011

Pleotrophic action of interferon gamma in human orbital fibroblasts

scientific article published on 01 March 1993

Potential Roles of CD34+ Fibrocytes Masquerading as Orbital Fibroblasts in Thyroid-Associated Ophthalmopathy

scientific article published on 01 February 2019

Potential role for bone marrow-derived fibrocytes in the orbital fibroblast heterogeneity associated with thyroid-associated ophthalmopathy.

artículo científico publicado en 2010

Prostaglandin E2 elicits a morphological change in cultured orbital fibroblasts from patients with Graves ophthalmopathy

artículo científico publicado en 1994

Prostaglandin-endoperoxide H synthase-2 expression in human thyroid epithelium. Evidence for constitutive expression in vivo and in cultured KAT-50 cells.

artículo científico publicado en 1999

Recent insights into the pathogenesis and management of thyroid-associated ophthalmopathy

artículo científico publicado en 2008

Regulation by glucocorticoids of interferon gamma-induced HLA-DR antigen expression in cultured human orbital fibroblasts

artículo científico publicado el 1 de julio de 1992

Regulation of IL-1 receptor antagonist by TSH in fibrocytes and orbital fibroblasts.

scientific article published on 21 January 2014

Regulation of Lymphocyte Function by PPARgamma: Relevance to Thyroid Eye Disease-Related Inflammation

artículo científico publicado en 2008

Response to Krieger et al. re: "TSHR/IGF-1R Cross-Talk, Not IGF-1R Stimulating Antibodies, Mediates Graves' Ophthalmopathy Pathogenesis" (Thyroid 2017;27:746-747)

artículo científico publicado en 2017

Response to Letter to the Editor: "Elevated Serum Tetrac in Graves Disease: Potential Pathogenic Role in Thyroid-Associated Ophthalmopathy"

artículo científico publicado en 2019

Retinoic acid blockade of imidazole-induced tyrosinase expression in B16 melanoma cultures: similar effects of the active retinoid and triiodothyronine

artículo científico publicado en 1989

Retinoic acid can enhance the stimulation by thyroid hormone of heme oxygenase activity in the liver of thyroidectomized rats

artículo científico publicado en 1991

Retinoic acid inhibition of thyroxine binding to human transthyretin

scientific article published on 01 January 1994

Rituximab (Rituxan) therapy for severe thyroid-associated ophthalmopathy diminishes IGF-1R(+) T cells

artículo científico publicado en 2014

Rituximab treatment of patients with severe, corticosteroid-resistant thyroid-associated ophthalmopathy

artículo científico publicado en 2009

Role of insulin-like growth factor-1 (IGF-1) pathway in the pathogenesis of Graves' orbitopathy.

artículo científico publicado en 2012

Rosiglitazone-induced proptosis.

artículo científico publicado en 2005

Slit2 May Underlie Divergent Induction by Thyrotropin of IL-23 and IL-12 in Human Fibrocytes

scientific article published on 21 February 2020

Slit2 Modulates the Inflammatory Phenotype of Orbit-Infiltrating Fibrocytes in Graves' Disease.

artículo científico publicado en 2018

T helper type 1 and type 2 cytokines exert divergent influence on the induction of prostaglandin E2 and hyaluronan synthesis by interleukin-1beta in orbital fibroblasts: implications for the pathogenesis of thyroid-associated ophthalmopathy.

artículo científico publicado en 2005

TSH-receptor-expressing fibrocytes and thyroid-associated ophthalmopathy

artículo científico publicado en 2015

TSHR as a therapeutic target in Graves' disease

artículo científico publicado en 2017

Targeted biological therapies for Graves' disease and thyroid-associated ophthalmopathy. Focus on B-cell depletion with Rituximab

artículo científico publicado en 2011

Teprotumumab, an IGF-1R blocking monoclonal antibody inhibits TSH and IGF-1 action in fibrocytes.

artículo científico publicado en 2014

Teprotumumab: a novel therapeutic monoclonal antibody for thyroid-associated ophthalmopathy

artículo científico publicado en 2020

The consequences of inappropriate treatment because of failure to recognize the syndrome of pituitary and peripheral tissue resistance to thyroid hormone

artículo científico publicado en 1983

The insulin-like growth factor-I receptor and its role in thyroid-associated ophthalmopathy

artículo científico publicado en 2018

The putative role of fibroblasts in the pathogenesis of Graves' disease: evidence for the involvement of the insulin-like growth factor-1 receptor in fibroblast activation.

artículo científico publicado en 2003

Thyrotropin regulates IL-6 expression in CD34+ fibrocytes: clear delineation of its cAMP-independent actions.

artículo científico

Transforming growth factor beta1 and laminin-111 cooperate in the induction of interleukin-16 expression in synovial fibroblasts from patients with rheumatoid arthritis.

artículo científico publicado en 2010

Treating the thyroid in the presence of Graves' ophthalmopathy.

artículo científico publicado en 2012

Ultrastructural features of osmotic shock in mussel gill cilia ⬇️

artículo científico publicado el 1 de julio de 1977

Ultrastructure of cultured human orbital fibroblasts

artículo científico publicado en 1994

Unique attributes of orbital fibroblasts and global alterations in IGF-1 receptor signaling could explain thyroid-associated ophthalmopathy.

artículo científico publicado en 2008

Will biological agents supplant systemic glucocorticoids as the first-line treatment for thyroid-associated ophthalmopathy?

artículo científico publicado en 2019

n-Butyrate increases c-erb A oncogene expression in human colon fibroblasts

scientific article published on 01 January 1988

n-Butyrate induces plasminogen activator inhibitor type 1 messenger RNA in cultured Hep G2 cells

scientific article published on 01 April 1996

Lista de obras de Terry J. Smith

A novel ELISpot method for adherent cells

A population-based prospective study of optic neuritis

Activation of human orbital fibroblasts through CD40 engagement results in a dramatic induction of hyaluronan synthesis and prostaglandin endoperoxide H synthase-2 expression. Insights into potential pathogenic mechanisms of thyroid-associated ophth

Advances in understanding autoimmune pituitary disease: standardized methods for autoantibody detection

Assessment of rapid morphological changes associated with elevated cAMP levels in human orbital fibroblasts

B cell depletion in Graves' disease: the right answer to the wrong question?

Bidimensional gel electrophoretic analysis of protein synthesis and response to interferon-gamma in cultured human dermal fibroblasts

Building the Case for Insulin-Like Growth Factor Receptor-I Involvement in Thyroid-Associated Ophthalmopathy.

CD34- Orbital Fibroblasts From Patients With Thyroid-Associated Ophthalmopathy Modulate TNF-α Expression in CD34+ Fibroblasts and Fibrocytes.

CD40 Expression in Fibrocytes Is Induced by TSH: Potential Synergistic Immune Activation

Cerebrospinal fluid biomarkers for predicting development of multiple sclerosis in acute optic neuritis: a population-based prospective cohort study

Challenges in Orphan Drug Development: Identification of Effective Therapy for Thyroid-Associated Ophthalmopathy

Characterization of Regulatory B Cells in Graves' Disease and Hashimoto's Thyroiditis

Characterization of the anaemia associated with Graves' disease

Circulating mononuclear cells from euthyroid patients with thyroid-associated ophthalmopathy exhibit characteristic phenotypes.

Collaborative International Research in Clinical and Longitudinal Experience Study in NMOSD

Current concepts in the molecular pathogenesis of thyroid-associated ophthalmopathy.

Current perspective on the pathogenesis of Graves' disease and ophthalmopathy.

Cyclooxygenases as the principal targets for the actions of NSAIDs

Cytokine-induced lymphocyte chemoattraction from cultured human thyrocytes: evidence for interleukin-16 and regulated upon activation, normal T cell expressed, and secreted expression

Cytokines are both villains and potential therapeutic targets in thyroid-associated ophthalmopathy: From bench to bedside.

Cytokines, Graves' disease, and thyroid-associated ophthalmopathy

Cytoplasmic prostaglandin E2 synthase is dominantly expressed in cultured KAT-50 thyrocytes, cells that express constitutive prostaglandin-endoperoxide H synthase-2. Basis for low protaglandin E2 production.

Development of criteria for evaluating clinical response in thyroid eye disease using a modified Delphi technique

Divergent Sp1 protein levels may underlie differential expression of UDP-glucose dehydrogenase by fibroblasts: role in susceptibility to orbital Graves disease.

Divergent expression of IL-1 receptor antagonists in CD34⁺ fibrocytes and orbital fibroblasts in thyroid-associated ophthalmopathy: contribution of fibrocytes to orbital inflammation

Evidence of adipocyte differentiation in human orbital fibroblasts in primary culture

Expression of thyrotropin receptor, thyroglobulin, sodium-iodide symporter, and thyroperoxidase by fibrocytes depends on AIRE.

Fibroblasts as sentinel cells: role of the CDcd40-CDcd40 ligand system in fibroblast activation and lung inflammation and fibrosis

Fibroblasts expressing the thyrotropin receptor overarch thyroid and orbit in Graves' disease.

Glucocorticoid regulation of glycosaminoglycan synthesis in cultured human skin fibroblasts: evidence for a receptor-mediated mechanism involving effects on specific de novo protein synthesis

Glucocorticoids enhance glucose uptake and affect differentiation and beta-adrenergic responsiveness in muscle cell cultures ⬇️

Graves' Disease

Graves' Disease.

HIF2A-LOX pathway promotes fibrotic tissue remodeling in thyroid-associated orbitopathy

Histopathology of brow fat in thyroid-associated orbitopathy.

Human fibrocytes express multiple antigens associated with autoimmune endocrine diseases

Hyaluronan accumulation in thyroid tissue: evidence for contributions from epithelial cells and fibroblasts.

IGF-I receptor and thyroid-associated ophthalmopathy

Immune mechanisms in thyroid eye disease.

Immunoglobulin G from patients with Graves' disease induces interleukin-16 and RANTES expression in cultured human thyrocytes: a putative mechanism for T-cell infiltration of the thyroid in autoimmune disease.

Immunoglobulins from patients with Graves' disease induce hyaluronan synthesis in their orbital fibroblasts through the self-antigen, insulin-like growth factor-I receptor.

Immunopathogenesis of thyroid eye disease: emerging paradigms

Inclusion of brain volume loss in a revised measure of 'no evidence of disease activity' (NEDA-4) in relapsing-remitting multiple sclerosis

Increased expression of TSH receptor by fibrocytes in thyroid-associated ophthalmopathy leads to chemokine production.

Increased generation of fibrocytes in thyroid-associated ophthalmopathy

Induction of heme oxygenase mRNA by cobalt protoporphyrin in rat liver

Insights into the role of fibroblasts in human autoimmune diseases.

Insulin-like Growth Factor-I Receptor and Thyroid-Associated Ophthalmopathy

Integrative continuum: accelerating therapeutic advances in rare autoimmune diseases

Interleukin-4 induces 15-lipoxygenase-1 expression in human orbital fibroblasts from patients with Graves disease. Evidence for anatomic site-selective actions of Th2 cytokines.

Interleukin-6 production in CD40-engaged fibrocytes in thyroid-associated ophthalmopathy: involvement of Akt and NF-κB.

Is IGF-I receptor a target for autoantibody generation in Graves' disease?

Leukoregulin induction of protein expression in human orbital fibroblasts: evidence for anatomical site-restricted cytokine-target cell interactions.

Magnetic resonance imaging findings at the first episode of acute optic neuritis

Molecular pathology of Muller's muscle in Graves' ophthalmopathy.

Neuromyelitis optica spectrum disorder: Patient experience and quality of life

New advances in understanding thyroid-associated ophthalmopathy and the potential role for insulin-like growth factor-I receptor.

Orbital fibroblasts from patients with thyroid-associated ophthalmopathy overexpress CD40: CD154 hyperinduces IL-6, IL-8, and MCP-1.

PGE2 induces IL-6 in orbital fibroblasts through EP2 receptors and increased gene promoter activity: implications to thyroid-associated ophthalmopathy

PI3K/AKT pathway mediates induction of IL-1RA by TSH in fibrocytes: modulation by PTEN

Pharmacotherapy: does selenium supplementation improve Graves ophthalmopathy?

Pleotrophic action of interferon gamma in human orbital fibroblasts

Potential Roles of CD34+ Fibrocytes Masquerading as Orbital Fibroblasts in Thyroid-Associated Ophthalmopathy

Potential role for bone marrow-derived fibrocytes in the orbital fibroblast heterogeneity associated with thyroid-associated ophthalmopathy.

Prostaglandin E2 elicits a morphological change in cultured orbital fibroblasts from patients with Graves ophthalmopathy

Prostaglandin-endoperoxide H synthase-2 expression in human thyroid epithelium. Evidence for constitutive expression in vivo and in cultured KAT-50 cells.

Recent insights into the pathogenesis and management of thyroid-associated ophthalmopathy

Regulation by glucocorticoids of interferon gamma-induced HLA-DR antigen expression in cultured human orbital fibroblasts

Regulation of IL-1 receptor antagonist by TSH in fibrocytes and orbital fibroblasts.

Regulation of Lymphocyte Function by PPARgamma: Relevance to Thyroid Eye Disease-Related Inflammation

Response to Krieger et al. re: "TSHR/IGF-1R Cross-Talk, Not IGF-1R Stimulating Antibodies, Mediates Graves' Ophthalmopathy Pathogenesis" (Thyroid 2017;27:746-747)

Response to Letter to the Editor: "Elevated Serum Tetrac in Graves Disease: Potential Pathogenic Role in Thyroid-Associated Ophthalmopathy"

Retinoic acid blockade of imidazole-induced tyrosinase expression in B16 melanoma cultures: similar effects of the active retinoid and triiodothyronine

Retinoic acid can enhance the stimulation by thyroid hormone of heme oxygenase activity in the liver of thyroidectomized rats

Retinoic acid inhibition of thyroxine binding to human transthyretin

Rituximab (Rituxan) therapy for severe thyroid-associated ophthalmopathy diminishes IGF-1R(+) T cells

Rituximab treatment of patients with severe, corticosteroid-resistant thyroid-associated ophthalmopathy

Role of insulin-like growth factor-1 (IGF-1) pathway in the pathogenesis of Graves' orbitopathy.