Lista de obras - Laura Breda - Dominio Público Uruguay

A combined approach for β-thalassemia based on gene therapy-mediated adult hemoglobin (HbA) production and fetal hemoglobin (HbF) induction

artículo científico publicado en 2012

A preclinical approach for gene therapy of beta-thalassemia.

artículo científico publicado en 2010

A validated cellular biobank for β-thalassemia

artículo científico publicado en 2016

Combining gene therapy and fetal hemoglobin induction for treatment of β-thalassemia

artículo científico publicado en 2013

Complexation to Cationic Microspheres of Double-Stranded Peptide Nucleic Acid-DNA Chimeras Exhibiting Decoy Activity

Decreased differentiation of erythroid cells exacerbates ineffective erythropoiesis in beta-thalassemia

artículo científico publicado en 2008

Decreased hepcidin mRNA expression in thalassemic mice

artículo científico publicado en 2004

Development of K562 cell clones expressing beta-globin mRNA carrying the beta039 thalassaemia mutation for the screening of correctors of stop-codon mutations

artículo científico publicado en 2009

Downregulation of hepcidin and haemojuvelin expression in the hepatocyte cell-line HepG2 induced by thalassaemic sera.

artículo científico publicado en 2006

Exploring the role of hepcidin, an antimicrobial and iron regulatory peptide, in increased iron absorption in beta-thalassemia

artículo científico publicado en 2005

Forced chromatin looping raises fetal hemoglobin in adult sickle cells to higher levels than pharmacologic inducers

artículo científico publicado en 2016

Formulations for natural and peptide nucleic acids based on cationic polymeric submicron particles.

artículo científico publicado en 2004

Gene therapy in thalassemia and hemoglobinopathies.

artículo científico publicado en 2009

Generation and Characterization of a Transgenic Mouse Carrying a Functional Human β -Globin Gene with the IVSI-6 Thalassemia Mutation.

artículo científico publicado en 2015

Hepcidin as a therapeutic tool to limit iron overload and improve anemia in β-thalassemic mice

artículo científico publicado en 2010

Identification and characterization of small molecules that inhibit nonsense-mediated RNA decay and suppress nonsense p53 mutations

artículo científico publicado en 2014

In vivo hematopoietic stem cell modification by mRNA delivery

artículo científico publicado en 2023

Ineffective erythropoiesis in beta-thalassemia is characterized by increased iron absorption mediated by down-regulation of hepcidin and up-regulation of ferroportin

artículo científico publicado en 2007

Modulators of erythropoiesis: emerging therapies for hemoglobinopathies and disorders of red cell production.

scientific article published on 18 January 2014

Production of beta-globin and adult hemoglobin following G418 treatment of erythroid precursor cells from homozygous beta(0)39 thalassemia patients

artículo científico publicado en 2009

Reactivation of developmentally silenced globin genes by forced chromatin looping.

artículo científico publicado en 2014

Recent trends in the gene therapy of β-thalassemia

artículo científico publicado en 2015

Role of iron in inducing oxidative stress in thalassemia: Can it be prevented by inhibition of absorption and by antioxidants?

artículo científico publicado en 2005

Therapeutic hemoglobin levels after gene transfer in β-thalassemia mice and in hematopoietic cells of β-thalassemia and sickle cells disease patients

artículo científico publicado en 2012

mRNA expression of iron regulatory genes in β-thalassemia intermedia and β-thalassemia major mouse models

article

Lista de obras de Laura Breda

A combined approach for β-thalassemia based on gene therapy-mediated adult hemoglobin (HbA) production and fetal hemoglobin (HbF) induction

A preclinical approach for gene therapy of beta-thalassemia.

A validated cellular biobank for β-thalassemia

Combining gene therapy and fetal hemoglobin induction for treatment of β-thalassemia

Complexation to Cationic Microspheres of Double-Stranded Peptide Nucleic Acid-DNA Chimeras Exhibiting Decoy Activity

Decreased differentiation of erythroid cells exacerbates ineffective erythropoiesis in beta-thalassemia

Decreased hepcidin mRNA expression in thalassemic mice

Development of K562 cell clones expressing beta-globin mRNA carrying the beta039 thalassaemia mutation for the screening of correctors of stop-codon mutations

Downregulation of hepcidin and haemojuvelin expression in the hepatocyte cell-line HepG2 induced by thalassaemic sera.

Exploring the role of hepcidin, an antimicrobial and iron regulatory peptide, in increased iron absorption in beta-thalassemia

Forced chromatin looping raises fetal hemoglobin in adult sickle cells to higher levels than pharmacologic inducers

Formulations for natural and peptide nucleic acids based on cationic polymeric submicron particles.

Gene therapy in thalassemia and hemoglobinopathies.

Generation and Characterization of a Transgenic Mouse Carrying a Functional Human β -Globin Gene with the IVSI-6 Thalassemia Mutation.

Hepcidin as a therapeutic tool to limit iron overload and improve anemia in β-thalassemic mice

Identification and characterization of small molecules that inhibit nonsense-mediated RNA decay and suppress nonsense p53 mutations

In vivo hematopoietic stem cell modification by mRNA delivery

Ineffective erythropoiesis in beta-thalassemia is characterized by increased iron absorption mediated by down-regulation of hepcidin and up-regulation of ferroportin

Modulators of erythropoiesis: emerging therapies for hemoglobinopathies and disorders of red cell production.

Production of beta-globin and adult hemoglobin following G418 treatment of erythroid precursor cells from homozygous beta(0)39 thalassemia patients

Reactivation of developmentally silenced globin genes by forced chromatin looping.

Recent trends in the gene therapy of β-thalassemia

Role of iron in inducing oxidative stress in thalassemia: Can it be prevented by inhibition of absorption and by antioxidants?

Therapeutic hemoglobin levels after gene transfer in β-thalassemia mice and in hematopoietic cells of β-thalassemia and sickle cells disease patients

mRNA expression of iron regulatory genes in β-thalassemia intermedia and β-thalassemia major mouse models