Lista de obras - Paula Morales - Dominio Público Uruguay

(R)-N-(1-Methyl-2-hydroxyethyl)-13-(S)-methyl-arachidonamide (AMG315): A Novel Chiral Potent Endocannabinoid Ligand with Stability to Metabolizing Enzymes

scientific article published on 21 September 2018

A Molecular Modeling Approach to Identify Novel Inhibitors of the Major Facilitator Superfamily of Efflux Pump Transporters

artículo científico publicado en 2019

A critical review of both the synthesis approach and the receptor profile of the 8-chloro-1-(2',4'-dichlorophenyl)-N-piperidin-1-yl-1,4,5,6-tetrahydrobenzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamide and analogue derivatives.

artículo científico publicado en 2016

An Overview on Medicinal Chemistry of Synthetic and Natural Derivatives of Cannabidiol

artículo científico publicado en 2017

An Update on Non-CB1, Non-CB2 Cannabinoid Related G-Protein-Coupled Receptors

artículo científico publicado en 2017

Antichagasic and trichomonacidal activity of 1-substituted 2-benzyl-5-nitroindazolin-3-ones and 3-alkoxy-2-benzyl-5-nitro-2H-indazoles.

artículo científico publicado en 2016

Antitumor Cannabinoid Chemotypes: Structural Insights

artículo científico publicado en 2019

Biological characterization of PM226, a chromenoisoxazole, as a selective CB2 receptor agonist with neuroprotective profile.

artículo científico publicado en 2016

CBD: A New Hope?

scientific article published on 29 April 2019

Cannabidiol skews biased agonism at cannabinoid CB1 and CB2 receptors with smaller effect in CB1-CB2 heteroreceptor complexes

article

Cannabinoid Ligands Targeting TRP Channels

artículo científico publicado en 2018

Cannabinoid receptor 2 (CB2) agonists and antagonists: a patent update

artículo científico publicado en 2016

Chromenopyrazole, a Versatile Cannabinoid Scaffold with in Vivo Activity in a Model of Multiple Sclerosis

artículo científico publicado en 2016

Chromenopyrazoles: non-psychoactive and selective CB₁ cannabinoid agonists with peripheral antinociceptive properties

artículo científico publicado en 2012

Corrigendum to "Biological characterization of PM226, a chromenoisoxazole, as a selective CB2 receptor agonist with neuroprotective profile" [Pharmacol. Res. 110 (August 2016) (2016) 205-215].

artículo científico publicado en 2017

Description of a bivalent cannabinoid ligand with hypophagic properties

artículo científico publicado en 2013

Design and structural characterisation of monomeric water-soluble α-helix and β-hairpin peptides: State-of-the-art

scientific article published on 20 November 2018

Emerging strategies targeting CB2 cannabinoid receptor: Biased agonism and allosterism

artículo científico publicado en 2018

Identification of Novel GPR55 Modulators Using Cell-Impedance-Based Label-Free Technology.

artículo científico publicado en 2016

Increased expression of cannabinoid CB2 and serotonin 5-HT1A heteroreceptor complexes in a model of newborn hypoxic-ischemic brain damage

scientific article published on 07 February 2019

Methods for the Development of In Silico GPCR Models

artículo científico publicado en 2017

Molecular Targets of the Phytocannabinoids: A Complex Picture

scientific article published on January 2017

New pyridazinone-4-carboxamides as new cannabinoid receptor type-2 inverse agonists: Synthesis, pharmacological data and molecular docking

artículo científico publicado en 2017

Potential metabolic and behavioural roles of the putative endocannabinoid receptors GPR18, GPR55 and GPR119 in feeding

scientific article published on 01 January 2019

Selective, nontoxic CB(2) cannabinoid o-quinone with in vivo activity against triple-negative breast cancer.

artículo científico publicado en 2015

Structural Insights into CB1 Receptor Biased Signaling

article

Structural Insights into β-arrestin/CB1 Receptor Interaction: NMR and CD Studies on Model Peptides

artículo científico publicado en 2020

Synthesis, Pharmacological Evaluation, and Docking Studies of Novel Pyridazinone-Based Cannabinoid Receptor Type 2 Ligands

artículo científico publicado en 2018

Synthesis, pharmacological evaluation and docking studies of pyrrole structure-based CB2 receptor antagonists.

artículo científico publicado en 2015

Synthetic cannabinoid quinones: preparation, in vitro antiproliferative effects and in vivo prostate antitumor activity.

artículo científico publicado en 2013

Targeting Cannabinoid CB2 Receptors in the Central Nervous System. Medicinal Chemistry Approaches with Focus on Neurodegenerative Disorders

artículo científico publicado en 2016

Towards A Molecular Understanding of The Cannabinoid Related Orphan Receptor GPR18: A Focus on Its Constitutive Activity ⬇️

artículo científico publicado en 2019

Towards a better understanding of the cannabinoid-related orphan receptors GPR3, GPR6, and GPR12.

artículo científico publicado en 2018

Lista de obras de Paula Morales

(R)-N-(1-Methyl-2-hydroxyethyl)-13-(S)-methyl-arachidonamide (AMG315): A Novel Chiral Potent Endocannabinoid Ligand with Stability to Metabolizing Enzymes

A Molecular Modeling Approach to Identify Novel Inhibitors of the Major Facilitator Superfamily of Efflux Pump Transporters

A critical review of both the synthesis approach and the receptor profile of the 8-chloro-1-(2',4'-dichlorophenyl)-N-piperidin-1-yl-1,4,5,6-tetrahydrobenzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamide and analogue derivatives.

An Overview on Medicinal Chemistry of Synthetic and Natural Derivatives of Cannabidiol

An Update on Non-CB1, Non-CB2 Cannabinoid Related G-Protein-Coupled Receptors

Antichagasic and trichomonacidal activity of 1-substituted 2-benzyl-5-nitroindazolin-3-ones and 3-alkoxy-2-benzyl-5-nitro-2H-indazoles.

Antitumor Cannabinoid Chemotypes: Structural Insights

Biological characterization of PM226, a chromenoisoxazole, as a selective CB2 receptor agonist with neuroprotective profile.

CBD: A New Hope?

Cannabidiol skews biased agonism at cannabinoid CB1 and CB2 receptors with smaller effect in CB1-CB2 heteroreceptor complexes

Cannabinoid Ligands Targeting TRP Channels

Cannabinoid receptor 2 (CB2) agonists and antagonists: a patent update

Chromenopyrazole, a Versatile Cannabinoid Scaffold with in Vivo Activity in a Model of Multiple Sclerosis

Chromenopyrazoles: non-psychoactive and selective CB₁ cannabinoid agonists with peripheral antinociceptive properties

Corrigendum to "Biological characterization of PM226, a chromenoisoxazole, as a selective CB2 receptor agonist with neuroprotective profile" [Pharmacol. Res. 110 (August 2016) (2016) 205-215].

Description of a bivalent cannabinoid ligand with hypophagic properties

Design and structural characterisation of monomeric water-soluble α-helix and β-hairpin peptides: State-of-the-art

Emerging strategies targeting CB2 cannabinoid receptor: Biased agonism and allosterism

Identification of Novel GPR55 Modulators Using Cell-Impedance-Based Label-Free Technology.

Increased expression of cannabinoid CB2 and serotonin 5-HT1A heteroreceptor complexes in a model of newborn hypoxic-ischemic brain damage

Methods for the Development of In Silico GPCR Models

Molecular Targets of the Phytocannabinoids: A Complex Picture

New pyridazinone-4-carboxamides as new cannabinoid receptor type-2 inverse agonists: Synthesis, pharmacological data and molecular docking

Potential metabolic and behavioural roles of the putative endocannabinoid receptors GPR18, GPR55 and GPR119 in feeding

Selective, nontoxic CB(2) cannabinoid o-quinone with in vivo activity against triple-negative breast cancer.

Structural Insights into CB1 Receptor Biased Signaling

Structural Insights into β-arrestin/CB1 Receptor Interaction: NMR and CD Studies on Model Peptides

Synthesis, Pharmacological Evaluation, and Docking Studies of Novel Pyridazinone-Based Cannabinoid Receptor Type 2 Ligands

Synthesis, pharmacological evaluation and docking studies of pyrrole structure-based CB2 receptor antagonists.

Synthetic cannabinoid quinones: preparation, in vitro antiproliferative effects and in vivo prostate antitumor activity.

Targeting Cannabinoid CB2 Receptors in the Central Nervous System. Medicinal Chemistry Approaches with Focus on Neurodegenerative Disorders

Towards A Molecular Understanding of The Cannabinoid Related Orphan Receptor GPR18: A Focus on Its Constitutive Activity ⬇️

Towards a better understanding of the cannabinoid-related orphan receptors GPR3, GPR6, and GPR12.