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Lista de obras de Pierre Martineau

A focused antibody library for selecting scFvs expressed at high levels in the cytoplasm

artículo científico publicado en 2007

A genetic system to elicit and monitor antipeptide antibodies without peptide synthesis.

artículo científico publicado en 1991

A novel druglike spleen tyrosine kinase binder prevents anaphylactic shock when administered orally

artículo científico publicado en 2008

ABCG2 overexpression in colon cancer cells resistant to SN38 and in irinotecan-treated metastases.

artículo científico publicado en 2004

Antibody targeting of claudin-1 as a potential colorectal cancer therapy.

artículo científico publicado en 2017

By-Passing Large Screening Experiments Using Sequencing as a Tool to Identify scFv Fragments Targeting Atherosclerotic Lesions in a Novel In Vivo Phage Display Selection

artículo científico publicado el 7 de junio de 2012

Casein interactions studied by the surface plasmon resonance technique.

artículo científico publicado en 2002

Claudin gene expression profiles and clinical value in colorectal tumors classified according to their molecular subtype

article

Construction of a Synthetic Antibody Gene Library for the Selection of Intrabodies and Antibodies

artículo científico publicado en 2018

Crystallization of genetically engineered active maltose-binding proteins, including an immunogenic viral epitope insertion.

artículo científico publicado en 1990

Cyclophilin A as negative regulator of apoptosis by sequestering cytochrome c.

artículo científico publicado en 2010

Directed evolution of single-chain Fv for cytoplasmic expression using the beta-galactosidase complementation assay results in proteins highly susceptible to protease degradation and aggregation

artículo científico publicado en 2004

Efficient incorporation of a functional hyper-stable single-chain antibody fragment protein-IX fusion in the adenovirus capsid.

artículo científico publicado en 2007

Enhancement of radiation therapy by tumor necrosis factor alpha in human colon cancer using a bispecific antibody.

artículo científico publicado en 2003

Enzyme immunoassays using bispecific diabodies.

artículo científico publicado en 1997

Erratum to “Restricted Diversity of Antigen Binding Residues of Antibodies Revealed by Computational Alanine Scanning of 227 Antibody–Antigen Complexes” [J. Mol. Biol., 426, 2014, 3729–3743]

artículo científico publicado en 2015

Evaluation of several affinity chromatographic supports for the purification of maltose-binding protein from Escherichia coli

scientific article published on 01 February 1993

Expression and immunogenicity of the V3 loop from the envelope of human immunodeficiency virus type 1 in an attenuated aroA strain of Salmonella typhimurium upon genetic coupling to two Escherichia coli carrier proteins

artículo científico publicado en 1993

Expression of an antibody fragment at high levels in the bacterial cytoplasm

artículo científico publicado en 1998

Expression of heterologous peptides at two permissive sites of the MalE protein: antigenicity and immunogenicity of foreign B-cell and T-cell epitopes

artículo científico publicado en 1992

Expression of single-chain Fv fragments in E. coli cytoplasm.

artículo científico publicado en 2009

FOXO3a and the MAPK p38 are activated by cetuximab to induce cell death and inhibit cell proliferation and their expression predicts cetuximab efficacy in colorectal cancer.

artículo científico publicado en 2016

Femtosecond spectroscopy probes the folding quality of antibody fragments expressed as GFP fusions in the cytoplasm

artículo científico publicado en 2007

Generation of an intrabody-based reagent suitable for imaging endogenous proliferating cell nuclear antigen in living cancer cells

artículo científico publicado en 2014

Homogeneous processing and presentation of a recombined T cell epitope in inbred mice of different non-MHC genetic background

scientific article published on 01 September 1996

Immune responses to hybrid maltose-binding proteins

artículo científico publicado en 1993

Immunodominance of a recombinant T-cell epitope depends on its molecular environment

artículo científico publicado en 1993

Immunogenicity of viral B- and T-cell epitopes expressed in recombinant bacterial proteins.

artículo científico publicado en 1994

Impact of RNA degradation on gene expression profiles: assessment of different methods to reliably determine RNA quality

artículo científico publicado en 2006

In vitro folding and thermodynamic stability of an antibody fragment selected in vivo for high expression levels in Escherichia coli cytoplasm

scientific article published on 01 October 1999

In-cell intrabody selection from a diverse human library identifies C12orf4 protein as a new player in rodent mast cell degranulation

scientific journal article

Induction of T cell responses by chimeric bacterial proteins expressing several copies of a viral T cell epitope.

artículo científico publicado en 1993

Inhibition of Ataxia-Telangiectasia Mutated and RAD3-Related () Overcomes Oxaliplatin Resistance and Promotes Antitumor Immunity in Colorectal Cancer

artículo científico publicado en 2019

Inhibition of DDR1-BCR signalling by nilotinib as a new therapeutic strategy for metastatic colorectal cancer

artículo científico publicado en 2018

Letrozole sensitizes breast cancer cells to ionizing radiation

artículo científico publicado en 2004

MALDI imaging mass spectrometry and chemometric tools to discriminate highly similar colorectal cancer tissues

scientific article published on 10 October 2019

MAPK14/p38α confers irinotecan resistance to TP53-defective cells by inducing survival autophagy.

artículo científico publicado en 2012

Maltodextrin-binding protein hybrids carrying epitopes from the preS2 region of hepatitis B virus: expression, antibody-binding and preliminary crystallographic studies.

artículo científico publicado en 1997

Modulating the immunological properties of a linear B-cell epitope by insertion into permissive sites of the MalE protein.

artículo científico publicado en 1996

Molecular and cellular targeting in the expression of foreign polypeptides in bacteria

artículo científico publicado en 1992

Molecular subtypes of metastatic colorectal cancer are associated with patient response to irinotecan-based therapies.

artículo científico publicado en 2017

NMR studies on the flexibility of the poliovirus C3 linear epitope inserted into different sites of the maltose-binding protein.

artículo científico publicado en 1997

New Topoisomerase I mutations are associated with resistance to camptothecin

artículo científico publicado en 2011

Nucleocytoplasmic shuttling of antigen in mammalian cells conferred by a soluble versus insoluble single-chain antibody fragment equipped with import/export signals

scientific article published on 01 June 2003

Overcoming the crypticity of a viral T cell determinant by insertion into a chimeric bacterial protein.

artículo científico publicado en 1996

Overexpression of phosphoserine aminotransferase PSAT1 stimulates cell growth and increases chemoresistance of colon cancer cells

artículo científico publicado en 2008

Potentiation of ionising radiation by targeting tumour necrosis factor alpha using a bispecific antibody in human pancreatic cancer.

artículo científico publicado en 2003

Prognostic significance of TRAIL-R1 and TRAIL-R3 expression in metastatic colorectal carcinomas

artículo científico publicado en 2008

Radiocurability by targeting tumor necrosis factor-alpha using a bispecific antibody in carcinoembryonic antigen transgenic mice

scientific article published on 01 November 2007

Restricted diversity of antigen binding residues of antibodies revealed by computational alanine scanning of 227 antibody-antigen complexes

artículo científico publicado en 2014

Selection and mass spectrometry characterization of peptides targeting semiconductor surfaces

artículo científico publicado en 2009

Selection for intrabody solubility in mammalian cells using GFP fusions

artículo científico publicado en 2011

Solubility Characterization and Imaging of Intrabodies Using GFP-Fusions

artículo científico publicado en 2017

Sorafenib overcomes irinotecan resistance in colorectal cancer by inhibiting the ABCG2 drug-efflux pump.

artículo científico publicado en 2013

Specific extracellular matrix remodeling signature of colon hepatic metastases

artículo científico publicado en 2013

Specific in vivo labeling of tyrosinated α-tubulin and measurement of microtubule dynamics using a GFP tagged, cytoplasmically expressed recombinant antibody

artículo científico publicado en 2013

Synthetic customized scFv libraries.

artículo científico publicado en 2012

Targeting the p38 MAPK pathway inhibits irinotecan resistance in colon adenocarcinoma.

artículo científico publicado en 2010

Tyrosine kinase syk non-enzymatic inhibitors and potential anti-allergic drug-like compounds discovered by virtual and in vitro screening

artículo científico publicado en 2011

Use of physiological information based on grayscale images to improve mass spectrometry imaging data analysis from biological tissues

scientific article published on 03 May 2019

[Antibody alternative formats: antibody fragments and new frameworks]

scientific article published on 01 December 2019