Lista de obras - Christopher B Marshall - Dominio Público Uruguay

A Non-Canonical Calmodulin Target Motif Comprising a Polybasic Region and Lipidated Terminal Residue Regulates Localization

scientific article published on 15 April 2020

A comparative CEST NMR study of slow conformational dynamics of small GTPases complexed with GTP and GTP analogues

artículo científico publicado en 2013

A facile method for determining ice recrystallization inhibition by antifreeze proteins.

artículo científico publicado en 2003

An autoinhibited noncanonical mechanism of GTP hydrolysis by Rheb maintains mTORC1 homeostasis

artículo científico publicado en 2012

Antifreeze protein from freeze-tolerant grass has a beta-roll fold with an irregularly structured ice-binding site

artículo científico publicado en 2012

Biochemical Classification of Disease-associated Mutants of RAS-like Protein Expressed in Many Tissues (RIT1).

artículo científico publicado en 2016

Biochemical and structural characterization of an intramolecular interaction in FOXO3a and its binding with p53

artículo científico publicado en 2008

Calmodulin and STIM proteins: Two major calcium sensors in the cytoplasm and endoplasmic reticulum

artículo científico

Calmodulin disrupts plasma membrane localization of farnesylated KRAS4b by sequestering its lipid moiety

scientific article published on 31 March 2020

Characterization of the intrinsic and TSC2-GAP-regulated GTPase activity of Rheb by real-time NMR.

artículo científico publicado en 2009

Direct visualization of spruce budworm antifreeze protein interacting with ice crystals: basal plane affinity confers hyperactivity.

artículo científico publicado en 2008

Enhancing the activity of a beta-helical antifreeze protein by the engineered addition of coils

artículo científico publicado en 2004

Fluorescence microscopy evidence for quasi-permanent attachment of antifreeze proteins to ice surfaces.

artículo científico publicado en 2007

Forkhead followed by disordered tail: The intrinsically disordered regions of FOXO3a.

artículo científico publicado en 2015

High water mobility on the ice-binding surface of a hyperactive antifreeze protein.

artículo científico publicado en 2010

Hyperactive antifreeze protein from fish contains multiple ice-binding sites

artículo científico publicado en 2008

Hyperactive antifreeze protein from winter flounder is a very long rod-like dimer of alpha-helices.

artículo científico publicado en 2005

Hyperactive antifreeze protein in a fish

artículo científico publicado en 2004

Hyperactive antifreeze protein in flounder species. The sole freeze protectant in American plaice

scientific article published on 01 September 2005

MARK3-mediated phosphorylation of ARHGEF2 couples microtubules to the actin cytoskeleton to establish cell polarity.

artículo científico publicado en 2017

Mechanistic insight into GPCR-mediated activation of the microtubule-associated RhoA exchange factor GEF-H1.

artículo científico publicado en 2014

Mechanistic insight into the microtubule and actin cytoskeleton coupling through dynein-dependent RhoGEF inhibition.

artículo científico publicado en 2012

Membrane-dependent modulation of the mTOR activator Rheb: NMR observations of a GTPase tethered to a lipid-bilayer nanodisc

artículo científico publicado en 2013

Multiple Calmodulin-Binding Sites Positively and Negatively Regulate Arabidopsis CYCLIC NUCLEOTIDE-GATED CHANNEL12.

artículo científico publicado en 2016

Multiplexed Real-Time NMR GTPase Assay for Simultaneous Monitoring of Multiple Guanine Nucleotide Exchange Factor Activities from Human Cancer Cells and Organoids

artículo científico publicado en 2018

Multivalent assembly of KRAS with the RAS-binding and cysteine-rich domains of CRAF on the membrane

scientific article published on 15 May 2020

Oncogenic and RASopathy-associated K-RAS mutations relieve membrane-dependent occlusion of the effector-binding site

artículo científico publicado en 2015

Partitioning of fish and insect antifreeze proteins into ice suggests they bind with comparable affinity.

artículo científico publicado en 2004

Point mutations of the mTOR-RHEB pathway in renal cell carcinoma

artículo científico publicado en 2015

Probing the GTPase cycle with real-time NMR: GAP and GEF activities in cell extracts

artículo científico

Real-time NMR monitoring of biological activities in complex physiological environments

artículo científico publicado en 2015

Real-time NMR study of guanine nucleotide exchange and activation of RhoA by PDZ-RhoGEF.

artículo científico publicado en 2009

Real-time NMR study of three small GTPases reveals that fluorescent 2'(3')-O-(N-methylanthraniloyl)-tagged nucleotides alter hydrolysis and exchange kinetics.

artículo científico publicado en 2009

Spatiotemporal dynamics of GEF-H1 activation controlled by microtubule- and Src-mediated pathways

scientific article published on 16 August 2019

Structure-guided Mutation of the Conserved G3-box Glycine in Rheb Generates a Constitutively Activated Regulator of Mammalian Target of Rapamycin (mTOR)

artículo científico publicado en 2014

The RhoGEF GEF-H1 is required for oncogenic RAS signaling via KSR-1

artículo científico publicado en 2014

The basis for hyperactivity of antifreeze proteins.

artículo científico publicado en 2006

Transcriptional/epigenetic regulator CBP/p300 in tumorigenesis: structural and functional versatility in target recognition.

artículo científico publicado en 2013

[A novel antifreeze protein in fish in the North Atlantic]

scientific article published on 01 August 2004

p120RasGAP is a mediator of rho pathway activation and tumorigenicity in the DLD1 colorectal cancer cell line

artículo científico publicado en 2014

Lista de obras de Christopher B Marshall

A Non-Canonical Calmodulin Target Motif Comprising a Polybasic Region and Lipidated Terminal Residue Regulates Localization

A comparative CEST NMR study of slow conformational dynamics of small GTPases complexed with GTP and GTP analogues

A facile method for determining ice recrystallization inhibition by antifreeze proteins.

An autoinhibited noncanonical mechanism of GTP hydrolysis by Rheb maintains mTORC1 homeostasis

Antifreeze protein from freeze-tolerant grass has a beta-roll fold with an irregularly structured ice-binding site

Biochemical Classification of Disease-associated Mutants of RAS-like Protein Expressed in Many Tissues (RIT1).

Biochemical and structural characterization of an intramolecular interaction in FOXO3a and its binding with p53

Calmodulin and STIM proteins: Two major calcium sensors in the cytoplasm and endoplasmic reticulum

Calmodulin disrupts plasma membrane localization of farnesylated KRAS4b by sequestering its lipid moiety

Characterization of the intrinsic and TSC2-GAP-regulated GTPase activity of Rheb by real-time NMR.

Direct visualization of spruce budworm antifreeze protein interacting with ice crystals: basal plane affinity confers hyperactivity.

Enhancing the activity of a beta-helical antifreeze protein by the engineered addition of coils

Fluorescence microscopy evidence for quasi-permanent attachment of antifreeze proteins to ice surfaces.

Forkhead followed by disordered tail: The intrinsically disordered regions of FOXO3a.

High water mobility on the ice-binding surface of a hyperactive antifreeze protein.

Hyperactive antifreeze protein from fish contains multiple ice-binding sites

Hyperactive antifreeze protein from winter flounder is a very long rod-like dimer of alpha-helices.

Hyperactive antifreeze protein in a fish

Hyperactive antifreeze protein in flounder species. The sole freeze protectant in American plaice

MARK3-mediated phosphorylation of ARHGEF2 couples microtubules to the actin cytoskeleton to establish cell polarity.

Mechanistic insight into GPCR-mediated activation of the microtubule-associated RhoA exchange factor GEF-H1.

Mechanistic insight into the microtubule and actin cytoskeleton coupling through dynein-dependent RhoGEF inhibition.

Membrane-dependent modulation of the mTOR activator Rheb: NMR observations of a GTPase tethered to a lipid-bilayer nanodisc

Multiple Calmodulin-Binding Sites Positively and Negatively Regulate Arabidopsis CYCLIC NUCLEOTIDE-GATED CHANNEL12.

Multiplexed Real-Time NMR GTPase Assay for Simultaneous Monitoring of Multiple Guanine Nucleotide Exchange Factor Activities from Human Cancer Cells and Organoids

Multivalent assembly of KRAS with the RAS-binding and cysteine-rich domains of CRAF on the membrane

Oncogenic and RASopathy-associated K-RAS mutations relieve membrane-dependent occlusion of the effector-binding site

Partitioning of fish and insect antifreeze proteins into ice suggests they bind with comparable affinity.

Point mutations of the mTOR-RHEB pathway in renal cell carcinoma

Probing the GTPase cycle with real-time NMR: GAP and GEF activities in cell extracts

Real-time NMR monitoring of biological activities in complex physiological environments

Real-time NMR study of guanine nucleotide exchange and activation of RhoA by PDZ-RhoGEF.

Real-time NMR study of three small GTPases reveals that fluorescent 2'(3')-O-(N-methylanthraniloyl)-tagged nucleotides alter hydrolysis and exchange kinetics.

Spatiotemporal dynamics of GEF-H1 activation controlled by microtubule- and Src-mediated pathways

Structure-guided Mutation of the Conserved G3-box Glycine in Rheb Generates a Constitutively Activated Regulator of Mammalian Target of Rapamycin (mTOR)

The RhoGEF GEF-H1 is required for oncogenic RAS signaling via KSR-1

The basis for hyperactivity of antifreeze proteins.

Transcriptional/epigenetic regulator CBP/p300 in tumorigenesis: structural and functional versatility in target recognition.

[A novel antifreeze protein in fish in the North Atlantic]

p120RasGAP is a mediator of rho pathway activation and tumorigenicity in the DLD1 colorectal cancer cell line