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Lista de obras de Danny M. Hatters

A biosensor of SRC family kinase conformation by exposable tetracysteine useful for cell-based screening.

artículo científico publicado en 2014

A biosensor-based framework to measure latent proteostasis capacity

artículo científico publicado en 2018

A platform to view huntingtin exon 1 aggregation flux in the cell reveals divergent influences from chaperones hsp40 and hsp70.

artículo científico publicado en 2013

A thiol probe for measuring unfolded protein load and proteostasis in cells.

artículo científico publicado en 2017

AMP-activated protein kinase β-subunit requires internal motion for optimal carbohydrate binding

artículo científico publicado en 2012

Amino-terminal domain stability mediates apolipoprotein E aggregation into neurotoxic fibrils

artículo científico publicado en 2006

Apolipoprotein E structure: insights into function.

artículo científico publicado en 2006

Apolipoprotein E4 forms a molten globule. A potential basis for its association with disease.

artículo científico publicado en 2002

Application of flow cytometry to analyze intracellular location and trafficking of cargo in cell populations.

artículo científico publicado en 2015

Arginine in C9ORF72 Dipolypeptides Mediates Promiscuous Proteome Binding and Multiple Modes of Toxicity

scientific article published on 21 February 2020

Conformational detection of prion protein with biarsenical labeling and FlAsH fluorescence

artículo científico publicado en 2009

Conformational dynamics and self-association of intrinsically disordered Huntingtin exon 1 in cells

artículo científico publicado en 2017

Diagnostics for amyloid fibril formation: where to begin?

artículo científico publicado en 2011

Disease-Associated Polyglutamine Stretches in Monomeric Huntingtin Adopt a Compact Structure

artículo científico publicado en 2012

Distinct partitioning of ALS associated TDP-43, FUS and SOD1 mutants into cellular inclusions

artículo científico publicado en 2015

Engineering conformational destabilization into mouse apolipoprotein E. A model for a unique property of human apolipoprotein E4.

artículo científico publicado en 2005

Fibrillar amyloid protein present in atheroma activates CD36 signal transduction.

artículo científico publicado en 2003

Hidden information on protein function in censuses of proteome foldedness

artículo científico publicado en 2022

High-throughput quantitation of intracellular trafficking and organelle disruption by flow cytometry.

artículo científico publicado en 2014

Human apolipoprotein C-II forms twisted amyloid ribbons and closed loops

artículo científico publicado en 2000

Huntingtin Inclusions Trigger Cellular Quiescence, Deactivate Apoptosis, and Lead to Delayed Necrosis

artículo científico publicado en 2017

Identifying polyglutamine protein species in situ that best predict neurodegeneration

artículo científico publicado en 2011

Immiscible inclusion bodies formed by polyglutamine and poly(glycine-alanine) are enriched with distinct proteomes but converge in proteins that are risk factors for disease and involved in protein degradation

artículo científico publicado en 2020

Insight on the molecular envelope of lipid-bound apolipoprotein E from electron paramagnetic resonance spectroscopy.

scientific article published on 24 December 2008

Macromolecular crowding accelerates amyloid formation by human apolipoprotein C-II.

artículo científico publicado en 2001

Misfolded polyglutamine, polyalanine, and superoxide dismutase 1 aggregate via distinct pathways in the cell

scientific article published on 14 January 2014

Model of biologically active apolipoprotein E bound to dipalmitoylphosphatidylcholine

artículo científico publicado en 2005

Modest Declines in Proteome Quality Impair Hematopoietic Stem Cell Self-Renewal

artículo científico publicado en 2020

Modulation of apolipoprotein E structure by domain interaction: differences in lipid-bound and lipid-free forms

scientific article published on 01 August 2005

N-Terminal Fragments of Huntingtin Longer than Residue 170 form Visible Aggregates Independently to Polyglutamine Expansion.

artículo científico publicado en 2017

Nascent mutant Huntingtin exon 1 chains do not stall on ribosomes during translation but aggregates do recruit machinery involved in ribosome quality control and RNA

artículo científico publicado en 2020

Phospholipid complexation and association with apolipoprotein C-II: insights from mass spectrometry.

artículo científico publicado en 2003

Polyalanine expansions drive a shift into α-helical clusters without amyloid-fibril formation.

artículo científico publicado en 2015

Polyglutamine aggregation in Huntington and related diseases.

artículo científico publicado en 2012

Protein aggregation in cell biology: An aggregomics perspective of health and disease

scientific article published on 10 May 2018

Protein folding: Illuminating chaperone activity

artículo científico publicado en 2017

Putting huntingtin "aggregation" in view with windows into the cellular milieu.

artículo científico

SOD1 protein aggregates stimulate macropinocytosis in neurons to facilitate their propagation

artículo científico publicado en 2015

Sedimentation analysis of novel DNA structures formed by homo-oligonucleotides.

artículo científico publicado en 2001

SerpinB2 (PAI-2) Modulates Proteostasis via Binding Misfolded Proteins and Promotion of Cytoprotective Inclusion Formation

artículo científico publicado en 2015

Simultaneous binding of the anti-cancer IgM monoclonal antibody PAT-SM6 to low density lipoproteins and GRP78

artículo científico publicado en 2013

Structural and Functional Analysis of a Plant Resistance Protein TIR Domain Reveals Interfaces for Self-Association, Signaling, and Autoregulation

artículo científico publicado en 2011

Structural insights into the multifunctionality of rabies virus P3 protein

artículo científico publicado en 2023

Sub-micellar phospholipid accelerates amyloid formation by apolipoprotein C-II.

artículo científico publicado en 2001

Tadpole-like Conformations of Huntingtin Exon 1 Are Characterized by Conformational Heterogeneity that Persists regardless of Polyglutamine Length

scientific article published on 05 April 2018

The Asian Biophysics Association-supporting biophysics in the greater Asia region.

artículo científico publicado en 2019

The allosteric mechanism induced by protein kinase A (PKA) phosphorylation of dematin (band 4.9)

artículo científico publicado en 2013

The allosteric mechanism induced by protein kinase A (PKA) phosphorylation of dematin (band 4.9).

artículo científico publicado en 2015

The anti-cancer IgM monoclonal antibody PAT-SM6 binds with high avidity to the unfolded protein response regulator GRP78.

artículo científico publicado en 2012

The circularization of amyloid fibrils formed by apolipoprotein C-II.

artículo científico publicado en 2003

Tracking mutant huntingtin aggregation kinetics in cells reveals three major populations that include an invariant oligomer pool.

artículo científico publicado en 2010

Tracking protein aggregation and mislocalization in cells with flow cytometry

artículo científico publicado en 2012

Transcriptional profiles for distinct aggregation states of mutant Huntingtin exon 1 protein unmask new Huntington's disease pathways

artículo científico publicado en 2017

Tyrosine 416 is phosphorylated in the closed, repressed conformation of c-Src

artículo científico publicado en 2013

VLDL lipolysis products increase VLDL fluidity and convert apolipoprotein E4 into a more expanded conformation.

artículo científico publicado en 2009

Walking the tightrope: proteostasis and neurodegenerative disease

artículo científico publicado en 2016

Widespread remodeling of proteome solubility in response to different protein homeostasis stresses

scientific article published on 21 January 2020