Lista de obras - Jiyoun Lee - Dominio Público Uruguay

A steroid-conjugated contrast agent for magnetic resonance imaging of cell signaling

artículo científico publicado en 2005

Design, synthesis, biological evaluation and molecular modelling of 2-(2-aryloxyphenyl)-1,4-dihydroisoquinolin-3(2H)-ones: A novel class of TSPO ligands modulating amyloid-β-induced mPTP opening

artículo científico

Development of a smart activity-based probe to detect subcellular activity of asparaginyl endopeptidase in living cells

artículo científico publicado en 2017

Development of near-infrared fluorophore (NIRF)-labeled activity-based probes for in vivo imaging of legumain

artículo científico publicado en 2010

Discovery and biological evaluation of tetrahydrothieno[2,3-c]pyridine derivatives as selective metabotropic glutamate receptor 1 antagonists for the potential treatment of neuropathic pain.

artículo científico publicado en 2015

Discovery of 1-(3-(benzyloxy)pyridin-2-yl)-3-(2-(piperazin-1-yl)ethyl)urea: A new modulator for amyloid beta-induced mitochondrial dysfunction.

artículo científico

Discovery of benzimidazole derivatives as modulators of mitochondrial function: A potential treatment for Alzheimer's disease.

artículo científico publicado en 2016

Discovery of thienopyrrolotriazine derivatives to protect mitochondrial function against Aβ-induced neurotoxicity.

artículo científico publicado en 2017

Effect of side chain hydrophobicity and cationic charge on antimicrobial activity and cytotoxicity of helical peptoids.

artículo científico publicado en 2017

Functional imaging of legumain in cancer using a new quenched activity-based probe

artículo científico publicado en 2012

Helicity Modulation Improves the Selectivity of Antimicrobial Peptoids

scientific article published on 15 September 2020

Mitochondria-Targeting Peptoids

artículo científico publicado en 2018

Mitochondrial drug targets in neurodegenerative diseases.

artículo científico publicado en 2016

Mitochondrion-Targeting Peptides and Peptidomimetics: Recent Progress and Design Principles

artículo científico publicado en 2019

N-4-Substituted-benzyl-N'-tert-butylbenzyl thioureas as vanilloid receptor ligands: investigation on the role of methanesulfonamido group in antagonistic activity

artículo científico publicado en 2004

Novel quinazoline-urea analogues as modulators for Aβ-induced mitochondrial dysfunction: design, synthesis, and molecular docking study

artículo científico publicado en 2014

Nucleic acid recognition by Toll-like receptors is coupled to stepwise processing by cathepsins and asparagine endopeptidase.

artículo científico publicado en 2011

Porphyrin-peptoid conjugates: face-to-face display of porphyrins on peptoid helices

artículo científico publicado en 2013

Potent human glutaminyl cyclase inhibitors as potential anti-Alzheimer's agents: Structure-activity relationship study of Arg-mimetic region

artículo científico publicado en 2018

Prostate tumor specific peptide-peptoid hybrid prodrugs.

artículo científico publicado en 2015

Rational design, synthesis, and biological evaluation of progesterone-modified MRI contrast agents

article by Jiyoun Lee et al published July 2007 in Chemistry and Biology

Recent Advances in Organelle-Targeted Fluorescent Probes

artículo científico publicado en 2021

Synthesis and biological evaluation of aryl isoxazole derivatives as metabotropic glutamate receptor 1 antagonists: a potential treatment for neuropathic pain

artículo científico publicado en 2015

Synthesis and biological evaluation of aryloxazole derivatives as antimitotic and vascular-disrupting agents for cancer therapy

artículo científico publicado en 2013

Synthesis and evaluation of 2-(3-arylureido)pyridines and 2-(3-arylureido)pyrazines as potential modulators of Aβ-induced mitochondrial dysfunction in Alzheimer's disease.

artículo científico publicado en 2017

Synthesis and evaluation of aza-peptidyl inhibitors of the lysosomal asparaginyl endopeptidase, legumain ⬇️

artículo científico publicado el 21 de diciembre de 2011

Synthesis and evaluation of new pyridyl/pyrazinyl thiourea derivatives: Neuroprotection against amyloid-β-induced toxicity.

artículo científico publicado en 2017

Target deconvolution techniques in modern phenotypic profiling ⬇️

artículo científico publicado el 18 de enero de 2013

Lista de obras de Jiyoun Lee

A steroid-conjugated contrast agent for magnetic resonance imaging of cell signaling

Design, synthesis, biological evaluation and molecular modelling of 2-(2-aryloxyphenyl)-1,4-dihydroisoquinolin-3(2H)-ones: A novel class of TSPO ligands modulating amyloid-β-induced mPTP opening

Development of a smart activity-based probe to detect subcellular activity of asparaginyl endopeptidase in living cells

Development of near-infrared fluorophore (NIRF)-labeled activity-based probes for in vivo imaging of legumain

Discovery and biological evaluation of tetrahydrothieno[2,3-c]pyridine derivatives as selective metabotropic glutamate receptor 1 antagonists for the potential treatment of neuropathic pain.

Discovery of 1-(3-(benzyloxy)pyridin-2-yl)-3-(2-(piperazin-1-yl)ethyl)urea: A new modulator for amyloid beta-induced mitochondrial dysfunction.

Discovery of benzimidazole derivatives as modulators of mitochondrial function: A potential treatment for Alzheimer's disease.

Discovery of thienopyrrolotriazine derivatives to protect mitochondrial function against Aβ-induced neurotoxicity.

Effect of side chain hydrophobicity and cationic charge on antimicrobial activity and cytotoxicity of helical peptoids.

Functional imaging of legumain in cancer using a new quenched activity-based probe

Helicity Modulation Improves the Selectivity of Antimicrobial Peptoids

Mitochondria-Targeting Peptoids

Mitochondrial drug targets in neurodegenerative diseases.

Mitochondrion-Targeting Peptides and Peptidomimetics: Recent Progress and Design Principles

N-4-Substituted-benzyl-N'-tert-butylbenzyl thioureas as vanilloid receptor ligands: investigation on the role of methanesulfonamido group in antagonistic activity

Novel quinazoline-urea analogues as modulators for Aβ-induced mitochondrial dysfunction: design, synthesis, and molecular docking study

Nucleic acid recognition by Toll-like receptors is coupled to stepwise processing by cathepsins and asparagine endopeptidase.

Porphyrin-peptoid conjugates: face-to-face display of porphyrins on peptoid helices

Potent human glutaminyl cyclase inhibitors as potential anti-Alzheimer's agents: Structure-activity relationship study of Arg-mimetic region

Prostate tumor specific peptide-peptoid hybrid prodrugs.

Rational design, synthesis, and biological evaluation of progesterone-modified MRI contrast agents

Recent Advances in Organelle-Targeted Fluorescent Probes

Synthesis and biological evaluation of aryl isoxazole derivatives as metabotropic glutamate receptor 1 antagonists: a potential treatment for neuropathic pain

Synthesis and biological evaluation of aryloxazole derivatives as antimitotic and vascular-disrupting agents for cancer therapy

Synthesis and evaluation of 2-(3-arylureido)pyridines and 2-(3-arylureido)pyrazines as potential modulators of Aβ-induced mitochondrial dysfunction in Alzheimer's disease.

Synthesis and evaluation of aza-peptidyl inhibitors of the lysosomal asparaginyl endopeptidase, legumain ⬇️

Synthesis and evaluation of new pyridyl/pyrazinyl thiourea derivatives: Neuroprotection against amyloid-β-induced toxicity.

Target deconvolution techniques in modern phenotypic profiling ⬇️