Lista de obras - Omidreza Firuzi - Dominio Público Uruguay

2H-chromene derivatives bearing thiazolidine-2,4-dione, rhodanine or hydantoin moieties as potential anticancer agents.

artículo científico publicado en 2012

4-Methylcoumarin derivatives with anti-inflammatory effects in activated microglial cells

artículo científico publicado en 2014

5-Lipoxygenase gene disruption reduces amyloid-beta pathology in a mouse model of Alzheimer's disease

artículo científico publicado en 2007

5-Oxo-hexahydroquinoline Derivatives and Their Tetrahydroquinoline Counterparts as Multidrug Resistance Reversal Agents

artículo científico publicado en 2020

5-Oxo-hexahydroquinoline derivatives as modulators of P-gp, MRP1 and BCRP transporters to overcome multidrug resistance in cancer cells

scientific article published on 02 November 2018

5-Oxo-hexahydroquinoline: an attractive scaffold with diverse biological activities

scientific article published on 02 November 2018

A spectroelectrochemical and chemical study on oxidation of hydroxycinnamic acids in aprotic medium

Alkyl esters of hydroxycinnamic acids with improved antioxidant activity and lipophilicity protect PC12 cells against oxidative stress

artículo científico publicado en 2012

Alterations in oxidative stress biomarkers associated with mild hyperlipidemia and smoking

artículo científico publicado en 2011

Antioxidant activity assay based on the inhibition of oxidation and photobleaching of L-cysteine-capped CdTe quantum dots

artículo científico publicado en 2012

Antioxidant and prooxidant effects of quercetin on glyceraldehyde-3-phosphate dehydrogenase

scientific article published on 03 May 2007

Antioxidant properties of 4-methylcoumarins in in vitro cell-free systems.

artículo científico publicado en 2010

Antioxidant properties of hydroxycinnamic acids: a review of structure- activity relationships

artículo científico publicado en 2013

Antiradical and antioxidant activities of new bio-antioxidants

artículo científico publicado en 2011

Assessment of cytotoxicity of choline chloride-based natural deep eutectic solvents against human HEK-293 cells: A QSAR analysis

scientific article published on 15 June 2018

Atractylis gummifera L. poisoning: an ethnopharmacological review.

artículo científico publicado en 2005

Carthamus, Salvia and Stachys species protect neuronal cells against oxidative stress-induced apoptosis

artículo científico publicado en 2014

Cytotoxic activity and chemical constituents of Anthemis mirheydari

artículo científico publicado en 2016

Cytotoxic activity assessment, QSAR and docking study of novel bis-carboxamide derivatives of 4-pyrones synthesized by Ugi four-component reaction.

artículo científico publicado en 2013

Cytotoxic diterpenoids from the roots of Salvia lachnocalyx

Cytotoxic, antioxidant and antimicrobial effects of nine species of woundwort (Stachys) plants

artículo científico publicado en 2013

Derivatives of caffeic acid, a natural antioxidant, as the basis for the discovery of novel nonpeptidic neurotrophic agents

artículo científico publicado en 2017

Design and synthesis of novel 3,5-bis-N-(aryl/heteroaryl) carbamoyl-4-aryl-1,4-dihydropyridines as small molecule BACE-1 inhibitors

artículo científico publicado en 2013

Design, Synthesis and Evaluation of Cytotoxicity of Novel Chromeno[4,3‐b]quinoline Derivatives ⬇️

artículo científico publicado el 18 de noviembre de 2010

Design, preparation, and in vitro characterization of a trimodally-targeted nanomagnetic onco-theranostic system for cancer diagnosis and therapy

artículo científico publicado en 2015

Design, synthesis and biological evaluation of novel anti-cytokine 1,2,4-triazine derivatives.

artículo científico publicado en 2013

Dietary Phenolic Acids and Derivatives. Evaluation of the Antioxidant Activity of Sinapic Acid and Its Alkyl Esters

Discovery of imidazopyridines containing isoindoline-1,3-dione framework as a new class of BACE1 inhibitors: Design, synthesis and SAR analysis.

artículo científico publicado en 2017

Discovery of neurotrophic agents based on hydroxycinnamic acid scaffold

artículo científico publicado en 2016

Doughnut-shaped bovine serum albumin nanoparticles loaded with doxorubicin for overcoming multidrug-resistant in cancer cells.

artículo científico publicado en 2017

Effect of infliximab on the glycosylation of IgG of patients with rheumatoid arthritis

artículo científico publicado en 2007

Effects of silymarin on biochemical and oxidative stress markers in end-stage renal disease patients undergoing peritoneal dialysis

artículo científico publicado en 2016

Evaluation of the antioxidant activity of flavonoids by "ferric reducing antioxidant power" assay and cyclic voltammetry.

artículo científico publicado en 2004

HGF/MET pathway aberrations as diagnostic, prognostic, and predictive biomarkers in human cancers

artículo científico publicado en 2019

Hypochlorite scavenging activity of flavonoids.

artículo científico publicado en 2004

Inhibitors of Alzheimer's BACE-1 with 3,5-bis-N-(aryl/heteroaryl) carbamoyl-4-aryl-1,4-dihydropyridine structure

artículo científico publicado en 2014

Long Chain Alkyl Esters of Hydroxycinnamic Acids as Promising Anticancer Agents: Selective Induction of Apoptosis in Cancer Cells

artículo científico publicado en 2017

Modulation of ERK1/2 and Akt Pathways Involved in the Neurotrophic Action of Caffeic Acid Alkyl Esters

Modulation of neurotrophic signaling pathways by polyphenols

artículo científico publicado en 2016

Molecular dynamics simulation and molecular docking studies of 1,4-Dihydropyridines as P-glycoprotein's allosteric inhibitors

artículo científico publicado en 2016

Multi-target inhibitors against Alzheimer disease derived from 3-hydrazinyl 1,2,4-triazine scaffold containing pendant phenoxy methyl-1,2,3-triazole: Design, synthesis and biological evaluation

scientific article published on 29 November 2018

Multifunctional iminochromene-2H-carboxamide derivatives containing different aminomethylene triazole with BACE1 inhibitory, neuroprotective and metal chelating properties targeting Alzheimer's disease.

artículo científico publicado en 2017

N-(2-(Piperazin-1-yl)phenyl)arylamide Derivatives as β-Secretase (BACE1) Inhibitors: Simple Synthesis by Ugi Four-Component Reaction and Biological Evaluation

artículo científico publicado en 2015

Neuroprotective and Antioxidant Activities of 4-Methylcoumarins: Development of Structure-Activity Relationships.

artículo científico publicado en 2016

Never let it go: Stopping key mechanisms underlying metastasis to fight pancreatic cancer.

artículo científico publicado en 2017

Novel 5-oxo-hexahydroquinoline derivatives: design, synthesis, in vitro P-glycoprotein-mediated multidrug resistance reversal profile and molecular dynamics simulation study.

artículo científico publicado en 2017

Novel 9-(alkylthio)-Acenaphtho[1,2-e]-1,2,4-triazine derivatives: synthesis, cytotoxic activity and molecular docking studies on B-cell lymphoma 2 (Bcl-2).

artículo científico publicado en 2014

Novel folic acid-conjugated doxorubicin loaded β-lactoglobulin nanoparticles induce apoptosis in breast cancer cells

scientific article published on 23 August 2018

Novel indole-based melatonin analogues: Evaluation of antioxidant activity and protective effect against amyloid β-induced damage

artículo científico publicado en 2016

Oxidative Stress and Antioxidants in Neurological Diseases: Is There Still Hope?

artículo científico publicado en 2016

Oxidative Stress in Amyotrophic Lateral Sclerosis: Pathophysiology and Opportunities for Pharmacological Intervention

artículo científico publicado en 2020

Oxidative stress parameters in different systemic rheumatic diseases

artículo científico publicado en 2006

Parameters of oxidative stress status in healthy subjects: their correlations and stability after sample collection

artículo científico publicado en 2006

Pegylated and amphiphilic Chitosan coated manganese ferrite nanoparticles for pH-sensitive delivery of methotrexate: Synthesis and characterization

artículo científico publicado en 2016

Phenylimino-2H-chromen-3-carboxamide derivatives as novel small molecule inhibitors of β-secretase (BACE1).

artículo científico publicado en 2013

Polyoxygenated cinnamoylcoumarins as conformationally constrained analogs of cytotoxic diarylpentanoids: synthesis and biological activity.

artículo científico publicado en 2013

Protein oxidation markers in the serum and synovial fluid of psoriatic arthritis patients

artículo científico publicado en 2008

Reversal of multidrug resistance in cancer cells by novel asymmetrical 1,4-dihydropyridines.

artículo científico publicado en 2013

Reversing multi-drug tumor resistance to Paclitaxel by well-defined pH-sensitive amphiphilic polypeptide block copolymers via induction of lysosomal membrane permeabilization

artículo científico publicado en 2018

Specific oxidative stress parameters differently correlate with nailfold capillaroscopy changes and organ involvement in systemic sclerosis

artículo científico publicado en 2007

Structural Insight into Binding Mode of 9-Hydroxy Aristolochic Acid, Diclofenac and Indomethacin to PLA2.

artículo científico publicado en 2016

Structure-activity relationship studies of 4-methylcoumarin derivatives as anticancer agents

artículo científico publicado en 2015

Structure-based design, synthesis, molecular docking study and biological evaluation of 1,2,4-triazine derivatives acting as COX/15-LOX inhibitors with anti-oxidant activities

artículo científico publicado en 2016

Synthesis and antiproliferative activity evaluation of imidazole-based indeno[1,2-b]quinoline-9,11-dione derivatives.

artículo científico publicado en 2013

Synthesis and biological evaluation of quinazolinone-based hydrazones with potential use in Alzheimer's disease

artículo científico publicado en 2017

Synthesis and structure-activity relationship study of multi-target triazine derivatives as innovative candidates for treatment of Alzheimer's disease

artículo científico publicado en 2018

Tetrahydroquinolinone derivatives as potent P-glycoprotein inhibitors: design, synthesis, biological evaluation and molecular docking analysis

scientific article published on 23 August 2017

Lista de obras de Omidreza Firuzi

2H-chromene derivatives bearing thiazolidine-2,4-dione, rhodanine or hydantoin moieties as potential anticancer agents.

4-Methylcoumarin derivatives with anti-inflammatory effects in activated microglial cells

5-Lipoxygenase gene disruption reduces amyloid-beta pathology in a mouse model of Alzheimer's disease

5-Oxo-hexahydroquinoline Derivatives and Their Tetrahydroquinoline Counterparts as Multidrug Resistance Reversal Agents

5-Oxo-hexahydroquinoline derivatives as modulators of P-gp, MRP1 and BCRP transporters to overcome multidrug resistance in cancer cells

5-Oxo-hexahydroquinoline: an attractive scaffold with diverse biological activities

A spectroelectrochemical and chemical study on oxidation of hydroxycinnamic acids in aprotic medium

Alkyl esters of hydroxycinnamic acids with improved antioxidant activity and lipophilicity protect PC12 cells against oxidative stress

Alterations in oxidative stress biomarkers associated with mild hyperlipidemia and smoking

Antioxidant activity assay based on the inhibition of oxidation and photobleaching of L-cysteine-capped CdTe quantum dots

Antioxidant and prooxidant effects of quercetin on glyceraldehyde-3-phosphate dehydrogenase

Antioxidant properties of 4-methylcoumarins in in vitro cell-free systems.

Antioxidant properties of hydroxycinnamic acids: a review of structure- activity relationships

Antiradical and antioxidant activities of new bio-antioxidants

Assessment of cytotoxicity of choline chloride-based natural deep eutectic solvents against human HEK-293 cells: A QSAR analysis

Atractylis gummifera L. poisoning: an ethnopharmacological review.

Carthamus, Salvia and Stachys species protect neuronal cells against oxidative stress-induced apoptosis

Cytotoxic activity and chemical constituents of Anthemis mirheydari

Cytotoxic activity assessment, QSAR and docking study of novel bis-carboxamide derivatives of 4-pyrones synthesized by Ugi four-component reaction.

Cytotoxic diterpenoids from the roots of Salvia lachnocalyx

Cytotoxic, antioxidant and antimicrobial effects of nine species of woundwort (Stachys) plants

Derivatives of caffeic acid, a natural antioxidant, as the basis for the discovery of novel nonpeptidic neurotrophic agents

Design and synthesis of novel 3,5-bis-N-(aryl/heteroaryl) carbamoyl-4-aryl-1,4-dihydropyridines as small molecule BACE-1 inhibitors

Design, Synthesis and Evaluation of Cytotoxicity of Novel Chromeno[4,3‐b]quinoline Derivatives ⬇️

Design, preparation, and in vitro characterization of a trimodally-targeted nanomagnetic onco-theranostic system for cancer diagnosis and therapy

Design, synthesis and biological evaluation of novel anti-cytokine 1,2,4-triazine derivatives.

Dietary Phenolic Acids and Derivatives. Evaluation of the Antioxidant Activity of Sinapic Acid and Its Alkyl Esters

Discovery of imidazopyridines containing isoindoline-1,3-dione framework as a new class of BACE1 inhibitors: Design, synthesis and SAR analysis.

Discovery of neurotrophic agents based on hydroxycinnamic acid scaffold

Doughnut-shaped bovine serum albumin nanoparticles loaded with doxorubicin for overcoming multidrug-resistant in cancer cells.

Effect of infliximab on the glycosylation of IgG of patients with rheumatoid arthritis

Effects of silymarin on biochemical and oxidative stress markers in end-stage renal disease patients undergoing peritoneal dialysis

Evaluation of the antioxidant activity of flavonoids by "ferric reducing antioxidant power" assay and cyclic voltammetry.

HGF/MET pathway aberrations as diagnostic, prognostic, and predictive biomarkers in human cancers

Hypochlorite scavenging activity of flavonoids.

Inhibitors of Alzheimer's BACE-1 with 3,5-bis-N-(aryl/heteroaryl) carbamoyl-4-aryl-1,4-dihydropyridine structure

Long Chain Alkyl Esters of Hydroxycinnamic Acids as Promising Anticancer Agents: Selective Induction of Apoptosis in Cancer Cells

Modulation of ERK1/2 and Akt Pathways Involved in the Neurotrophic Action of Caffeic Acid Alkyl Esters

Modulation of neurotrophic signaling pathways by polyphenols

Molecular dynamics simulation and molecular docking studies of 1,4-Dihydropyridines as P-glycoprotein's allosteric inhibitors

Multi-target inhibitors against Alzheimer disease derived from 3-hydrazinyl 1,2,4-triazine scaffold containing pendant phenoxy methyl-1,2,3-triazole: Design, synthesis and biological evaluation

Multifunctional iminochromene-2H-carboxamide derivatives containing different aminomethylene triazole with BACE1 inhibitory, neuroprotective and metal chelating properties targeting Alzheimer's disease.

N-(2-(Piperazin-1-yl)phenyl)arylamide Derivatives as β-Secretase (BACE1) Inhibitors: Simple Synthesis by Ugi Four-Component Reaction and Biological Evaluation

Neuroprotective and Antioxidant Activities of 4-Methylcoumarins: Development of Structure-Activity Relationships.

Never let it go: Stopping key mechanisms underlying metastasis to fight pancreatic cancer.

Novel 5-oxo-hexahydroquinoline derivatives: design, synthesis, in vitro P-glycoprotein-mediated multidrug resistance reversal profile and molecular dynamics simulation study.

Novel 9-(alkylthio)-Acenaphtho[1,2-e]-1,2,4-triazine derivatives: synthesis, cytotoxic activity and molecular docking studies on B-cell lymphoma 2 (Bcl-2).

Novel folic acid-conjugated doxorubicin loaded β-lactoglobulin nanoparticles induce apoptosis in breast cancer cells

Novel indole-based melatonin analogues: Evaluation of antioxidant activity and protective effect against amyloid β-induced damage

Oxidative Stress and Antioxidants in Neurological Diseases: Is There Still Hope?

Oxidative Stress in Amyotrophic Lateral Sclerosis: Pathophysiology and Opportunities for Pharmacological Intervention

Oxidative stress parameters in different systemic rheumatic diseases

Parameters of oxidative stress status in healthy subjects: their correlations and stability after sample collection

Pegylated and amphiphilic Chitosan coated manganese ferrite nanoparticles for pH-sensitive delivery of methotrexate: Synthesis and characterization

Phenylimino-2H-chromen-3-carboxamide derivatives as novel small molecule inhibitors of β-secretase (BACE1).

Polyoxygenated cinnamoylcoumarins as conformationally constrained analogs of cytotoxic diarylpentanoids: synthesis and biological activity.

Protein oxidation markers in the serum and synovial fluid of psoriatic arthritis patients

Reversal of multidrug resistance in cancer cells by novel asymmetrical 1,4-dihydropyridines.

Reversing multi-drug tumor resistance to Paclitaxel by well-defined pH-sensitive amphiphilic polypeptide block copolymers via induction of lysosomal membrane permeabilization

Specific oxidative stress parameters differently correlate with nailfold capillaroscopy changes and organ involvement in systemic sclerosis

Structural Insight into Binding Mode of 9-Hydroxy Aristolochic Acid, Diclofenac and Indomethacin to PLA2.

Structure-activity relationship studies of 4-methylcoumarin derivatives as anticancer agents

Structure-based design, synthesis, molecular docking study and biological evaluation of 1,2,4-triazine derivatives acting as COX/15-LOX inhibitors with anti-oxidant activities

Synthesis and antiproliferative activity evaluation of imidazole-based indeno[1,2-b]quinoline-9,11-dione derivatives.

Synthesis and biological evaluation of quinazolinone-based hydrazones with potential use in Alzheimer's disease

Synthesis and structure-activity relationship study of multi-target triazine derivatives as innovative candidates for treatment of Alzheimer's disease

Tetrahydroquinolinone derivatives as potent P-glycoprotein inhibitors: design, synthesis, biological evaluation and molecular docking analysis