Lista de obras - Lee S. Weinstein - Dominio Público Uruguay

A Novel Mutation Adjacent to the Switch III Domain of Gsαin a Patient with Pseudohypoparathyroidism ⬇️

artículo científico publicado el 1 de octubre de 1997

A deletion hot-spot in exon 7 of the Gs alpha gene (GNAS1) in patients with Albright hereditary osteodystrophy.

artículo científico publicado en 1995

A heterozygous 4-bp deletion mutation in the Gs alpha gene (GNAS1) in a patient with Albright hereditary osteodystrophy

artículo científico publicado en 1992

A mutation in the heterotrimeric stimulatory guanine nucleotide binding protein alpha-subunit with impaired receptor-mediated activation because of elevated GTPase activity.

artículo científico publicado en 1999

A novel mutation in the switch 3 region of Gsalpha in a patient with Albright hereditary osteodystrophy impairs GDP binding and receptor activation

artículo científico publicado en 1998

Ablation of the Stimulatory G Protein α-Subunit in Renal Proximal Tubules Leads to Parathyroid Hormone-Resistance With Increased Renal Cyp24a1 mRNA Abundance and Reduced Serum 1,25-Dihydroxyvitamin D.

artículo científico publicado en 2015

Alternative Gnas gene products have opposite effects on glucose and lipid metabolism.

artículo científico publicado en 2005

An activating Gs alpha mutation is present in fibrous dysplasia of bone in the McCune-Albright syndrome.

artículo científico

Analysis of genomic imprinting of Gs alpha gene.

artículo científico publicado en 2002

Beta cell-specific deficiency of the stimulatory G protein alpha-subunit Gsalpha leads to reduced beta cell mass and insulin-deficient diabetes.

artículo científico publicado en 2007

Body mass index differences in pseudohypoparathyroidism type 1a versus pseudopseudohypoparathyroidism may implicate paternal imprinting of Galpha(s) in the development of human obesity

artículo científico publicado en 2007

Chondrocyte-specific knockout of the G protein G(s)alpha leads to epiphyseal and growth plate abnormalities and ectopic chondrocyte formation

artículo científico publicado en 2004

Cloning and characterization of the human gene for the alpha-subunit of Gi2, a GTP-binding signal transduction protein

artículo científico publicado en 1988

Continuous positive airway pressure in patients with heart failure

artículo científico publicado en 2003

Detection of mutations and polymorphisms of Gs alpha subunit gene by denaturing gradient gel electrophoresis

artículo científico publicado en 1994

Development and treatment of tertiary hyperparathyroidism in patients with pseudohypoparathyroidism type 1B

artículo científico publicado en 2012

Development of vascular renin expression in the kidney critically depends on the cyclic AMP pathway

artículo científico publicado en 2009

Distinct patterns of abnormal GNAS imprinting in familial and sporadic pseudohypoparathyroidism type IB

artículo científico publicado en 2004

Effects of deficiency of the G protein Gsα on energy and glucose homeostasis

artículo científico publicado en 2011

Fibroblast growth factor-23 is regulated by 1alpha,25-dihydroxyvitamin D.

artículo científico publicado en 2005

G protein mutations in human disease

artículo científico publicado en 1993

G(q/11)α and G(s)α mediate distinct physiological responses to central melanocortins

artículo científico publicado en 2015

G(s)alpha deficiency in adipose tissue leads to a lean phenotype with divergent effects on cold tolerance and diet-induced thermogenesis

artículo científico publicado en 2010

G(s)alpha mutations in fibrous dysplasia and McCune-Albright syndrome

artículo científico publicado en 2006

G-Protein α-Subunit Gsα Is Required for Craniofacial Morphogenesis

artículo científico publicado en 2016

GNAS haploinsufficiency leads to subcutaneous tumor formation with collagen and elastin deposition and calcification

artículo científico publicado en 2009

Genetic diseases associated with heterotrimeric G proteins

artículo científico publicado en 2006

Genetic mapping of the Gs-alpha subunit gene (GNAS1) to the distal long arm of chromosome 20 using a polymorphism detected by denaturing gradient gel electrophoresis.

artículo científico publicado en 1991

Gsα Deficiency in the Ventromedial Hypothalamus Enhances Leptin Sensitivity and Improves Glucose Homeostasis in Mice on a High-Fat Diet.

artículo científico publicado en 2015

Gsα deficiency in adipose tissue improves glucose metabolism and insulin sensitivity without an effect on body weight.

artículo científico publicado en 2015

Gsα deficiency in the dorsomedial hypothalamus underlies obesity associated with Gsα mutations.

artículo científico publicado en 2016

Gαs Relays Sphingosine-1-Phosphate Receptor 1 Signaling to Stabilize Vascular Endothelial-Cadherin at Endothelial Junctions to Control Mouse Embryonic Vascular Integrity

artículo científico publicado en 2015

Haematopoietic stem cells depend on Galpha(s)-mediated signalling to engraft bone marrow

artículo científico publicado en 2009

Identification and localization of G protein subunits in human spermatozoa

artículo científico publicado en 1999

Identification of a methylation imprint mark within the mouse Gnas locus

artículo científico publicado en 2000

Increased glucose tolerance and reduced adiposity in the absence of fasting hypoglycemia in mice with liver-specific Gs alpha deficiency

artículo científico publicado en 2005

Increased insulin sensitivity in Gsalpha knockout mice.

artículo científico publicado en 2001

Increased insulin sensitivity in paternal Gnas knockout mice is associated with increased lipid clearance.

artículo científico publicado en 2004

Inherited diseases involving g proteins and g protein-coupled receptors.

artículo científico publicado en 2004

Limited Parathyroidectomy in Multiple Endocrine Neoplasia Type 1-Associated Primary Hyperparathyroidism: A Setup for Failure.

artículo científico publicado en 2015

Loss of Gsα in the Postnatal Skeleton Leads to Low Bone Mass and a Blunted Response to Anabolic Parathyroid Hormone Therapy

artículo científico publicado en 2015

Minireview: GNAS: normal and abnormal functions.

artículo científico publicado en 2004

Multiple endocrine neoplasia type 1 variant with frequent prolactinoma and rare gastrinoma

artículo científico publicado en 2004

Osteoblastic regulation of B lymphopoiesis is mediated by Gs{alpha}-dependent signaling pathways

artículo científico publicado en 2008

Pancreas-specific Gsalpha deficiency has divergent effects on pancreatic alpha- and beta-cell proliferation

artículo científico publicado en 2010

Persistent primary hyperparathyroidism caused by adenomas identified in pharyngeal or adjacent structures

artículo científico publicado en 2003

Pseudohypoparathyroidism type Ib is not caused by mutations in the coding exons of the human parathyroid hormone (PTH)/PTH-related peptide receptor gene

artículo científico publicado en 1995

Receptor-effector coupling by G proteins: implications for normal and abnormal signal transduction

artículo científico publicado el 1 de agosto de 1992

Receptor-mediated adenylyl cyclase activation through XLalpha(s), the extra-large variant of the stimulatory G protein alpha-subunit.

artículo científico publicado en 2002

Regulation of renin in mice with Cre recombinase-mediated deletion of G protein Gsalpha in juxtaglomerular cells.

artículo científico publicado en 2006

Removal of the N-terminal extension of cardiac troponin I as a functional compensation for impaired myocardial beta-adrenergic signaling

artículo científico publicado en 2008

Renal failure in mice with Gsalpha deletion in juxtaglomerular cells.

artículo científico publicado en 2010

Reoperation for hyperparathyroidism in multiple endocrine neoplasia type 1.

artículo científico publicado en 2001

Reoperation for parathyroid adenoma: a contemporary experience

artículo científico publicado en 2009

Reoperative Surgery in Patients with Multiple Endocrine Neoplasia Type 1 Associated Primary Hyperparathyroidism.

artículo científico publicado en 2016

Results of heterotopic parathyroid autotransplantation: a 13-year experience

artículo científico publicado en 1999

Results of initial operation for hyperparathyroidism in patients with multiple endocrine neoplasia type 1

artículo científico publicado en 2003

Role of G(s)α in central regulation of energy and glucose metabolism.

artículo científico publicado en 2014

Severe endocrine and nonendocrine manifestations of the McCune-Albright syndrome associated with activating mutations of stimulatory G protein GS.

artículo científico publicado en 1993

Severe obesity and insulin resistance due to deletion of the maternal Gsalpha allele is reversed by paternal deletion of the Gsalpha imprint control region

artículo científico publicado en 2008

Skeletal abnormalities and extra-skeletal ossification in mice with restricted Gsalpha deletion caused by a renin promoter-Cre transgene.

artículo científico publicado en 2007

Stimulation of renin secretion by angiotensin II blockade is Gsalpha-dependent

artículo científico publicado en 2010

Stimulatory G protein directly regulates hypertrophic differentiation of growth plate cartilage in vivo.

scholarly article

Stimulatory guanine nucleotide binding protein subunit 1 mutation in two siblings with pseudohypoparathyroidism type 1a and mother with pseudopseudohypoparathyroidism.

artículo científico publicado en 1999

Studies in a kindred with parathyroid carcinoma

scientific article published on 01 August 1992

The Role of Genomic Imprinting of Galpha in the Pathogenesis of Albright Hereditary Osteodystrophy

artículo científico publicado en 1999

The alternative stimulatory G protein alpha-subunit XLalphas is a critical regulator of energy and glucose metabolism and sympathetic nerve activity in adult mice

artículo científico publicado en 2006

The parathyroid/pituitary variant of multiple endocrine neoplasia type 1 usually has causes other than p27Kip1 mutations

artículo científico publicado en 2007

The role of G-protein in matrix-mediated motility of highly and poorly invasive melanoma cells.

artículo científico publicado en 1991

The role of GNAS and other imprinted genes in the development of obesity.

artículo científico publicado en 2009

The role of tissue-specific imprinting as a source of phenotypic heterogeneity in human disease.

artículo científico publicado en 2001

The stimulatory G protein alpha-subunit Gs alpha is imprinted in human thyroid glands: implications for thyroid function in pseudohypoparathyroidism types 1A and 1B.

artículo científico publicado en 2003

The stimulatory G protein alpha-subunit gene: mutations and imprinting lead to complex phenotypes

artículo científico publicado en 2001

Thyrotrophin receptor signaling dependence of Braf-induced thyroid tumor initiation in mice

artículo científico publicado en 2011

Tissue-specific imprinting of the G protein Gsalpha is associated with tissue-specific differences in histone methylation

artículo científico publicado en 2004

Transgenic overexpression of the extra-large Gsα variant XLαs enhances Gsα-mediated responses in the mouse renal proximal tubule in vivo

scientific journal article

Wnt/β-catenin signaling is differentially regulated by Gα proteins and contributes to fibrous dysplasia ⬇️

artículo científico publicado el 21 de noviembre de 2011

Lista de obras de Lee S. Weinstein

A Novel Mutation Adjacent to the Switch III Domain of Gsαin a Patient with Pseudohypoparathyroidism ⬇️

A deletion hot-spot in exon 7 of the Gs alpha gene (GNAS1) in patients with Albright hereditary osteodystrophy.

A heterozygous 4-bp deletion mutation in the Gs alpha gene (GNAS1) in a patient with Albright hereditary osteodystrophy

A mutation in the heterotrimeric stimulatory guanine nucleotide binding protein alpha-subunit with impaired receptor-mediated activation because of elevated GTPase activity.

A novel mutation in the switch 3 region of Gsalpha in a patient with Albright hereditary osteodystrophy impairs GDP binding and receptor activation

Ablation of the Stimulatory G Protein α-Subunit in Renal Proximal Tubules Leads to Parathyroid Hormone-Resistance With Increased Renal Cyp24a1 mRNA Abundance and Reduced Serum 1,25-Dihydroxyvitamin D.

Alternative Gnas gene products have opposite effects on glucose and lipid metabolism.

An activating Gs alpha mutation is present in fibrous dysplasia of bone in the McCune-Albright syndrome.

Analysis of genomic imprinting of Gs alpha gene.

Beta cell-specific deficiency of the stimulatory G protein alpha-subunit Gsalpha leads to reduced beta cell mass and insulin-deficient diabetes.

Body mass index differences in pseudohypoparathyroidism type 1a versus pseudopseudohypoparathyroidism may implicate paternal imprinting of Galpha(s) in the development of human obesity

Chondrocyte-specific knockout of the G protein G(s)alpha leads to epiphyseal and growth plate abnormalities and ectopic chondrocyte formation

Cloning and characterization of the human gene for the alpha-subunit of Gi2, a GTP-binding signal transduction protein

Continuous positive airway pressure in patients with heart failure

Detection of mutations and polymorphisms of Gs alpha subunit gene by denaturing gradient gel electrophoresis

Development and treatment of tertiary hyperparathyroidism in patients with pseudohypoparathyroidism type 1B

Development of vascular renin expression in the kidney critically depends on the cyclic AMP pathway

Distinct patterns of abnormal GNAS imprinting in familial and sporadic pseudohypoparathyroidism type IB

Effects of deficiency of the G protein Gsα on energy and glucose homeostasis

Fibroblast growth factor-23 is regulated by 1alpha,25-dihydroxyvitamin D.

G protein mutations in human disease

G(q/11)α and G(s)α mediate distinct physiological responses to central melanocortins

G(s)alpha deficiency in adipose tissue leads to a lean phenotype with divergent effects on cold tolerance and diet-induced thermogenesis

G(s)alpha mutations in fibrous dysplasia and McCune-Albright syndrome

G-Protein α-Subunit Gsα Is Required for Craniofacial Morphogenesis

GNAS haploinsufficiency leads to subcutaneous tumor formation with collagen and elastin deposition and calcification

Genetic diseases associated with heterotrimeric G proteins

Genetic mapping of the Gs-alpha subunit gene (GNAS1) to the distal long arm of chromosome 20 using a polymorphism detected by denaturing gradient gel electrophoresis.

Gsα Deficiency in the Ventromedial Hypothalamus Enhances Leptin Sensitivity and Improves Glucose Homeostasis in Mice on a High-Fat Diet.

Gsα deficiency in adipose tissue improves glucose metabolism and insulin sensitivity without an effect on body weight.

Gsα deficiency in the dorsomedial hypothalamus underlies obesity associated with Gsα mutations.

Gαs Relays Sphingosine-1-Phosphate Receptor 1 Signaling to Stabilize Vascular Endothelial-Cadherin at Endothelial Junctions to Control Mouse Embryonic Vascular Integrity

Haematopoietic stem cells depend on Galpha(s)-mediated signalling to engraft bone marrow

Identification and localization of G protein subunits in human spermatozoa

Identification of a methylation imprint mark within the mouse Gnas locus

Increased glucose tolerance and reduced adiposity in the absence of fasting hypoglycemia in mice with liver-specific Gs alpha deficiency

Increased insulin sensitivity in Gsalpha knockout mice.

Increased insulin sensitivity in paternal Gnas knockout mice is associated with increased lipid clearance.

Inherited diseases involving g proteins and g protein-coupled receptors.

Limited Parathyroidectomy in Multiple Endocrine Neoplasia Type 1-Associated Primary Hyperparathyroidism: A Setup for Failure.

Loss of Gsα in the Postnatal Skeleton Leads to Low Bone Mass and a Blunted Response to Anabolic Parathyroid Hormone Therapy

Minireview: GNAS: normal and abnormal functions.

Multiple endocrine neoplasia type 1 variant with frequent prolactinoma and rare gastrinoma

Osteoblastic regulation of B lymphopoiesis is mediated by Gs{alpha}-dependent signaling pathways

Pancreas-specific Gsalpha deficiency has divergent effects on pancreatic alpha- and beta-cell proliferation

Persistent primary hyperparathyroidism caused by adenomas identified in pharyngeal or adjacent structures

Pseudohypoparathyroidism type Ib is not caused by mutations in the coding exons of the human parathyroid hormone (PTH)/PTH-related peptide receptor gene

Receptor-effector coupling by G proteins: implications for normal and abnormal signal transduction

Receptor-mediated adenylyl cyclase activation through XLalpha(s), the extra-large variant of the stimulatory G protein alpha-subunit.

Regulation of renin in mice with Cre recombinase-mediated deletion of G protein Gsalpha in juxtaglomerular cells.

Removal of the N-terminal extension of cardiac troponin I as a functional compensation for impaired myocardial beta-adrenergic signaling

Renal failure in mice with Gsalpha deletion in juxtaglomerular cells.

Reoperation for hyperparathyroidism in multiple endocrine neoplasia type 1.

Reoperation for parathyroid adenoma: a contemporary experience

Reoperative Surgery in Patients with Multiple Endocrine Neoplasia Type 1 Associated Primary Hyperparathyroidism.

Results of heterotopic parathyroid autotransplantation: a 13-year experience

Results of initial operation for hyperparathyroidism in patients with multiple endocrine neoplasia type 1

Role of G(s)α in central regulation of energy and glucose metabolism.

Severe endocrine and nonendocrine manifestations of the McCune-Albright syndrome associated with activating mutations of stimulatory G protein GS.

Severe obesity and insulin resistance due to deletion of the maternal Gsalpha allele is reversed by paternal deletion of the Gsalpha imprint control region

Skeletal abnormalities and extra-skeletal ossification in mice with restricted Gsalpha deletion caused by a renin promoter-Cre transgene.

Stimulation of renin secretion by angiotensin II blockade is Gsalpha-dependent

Stimulatory G protein directly regulates hypertrophic differentiation of growth plate cartilage in vivo.

Stimulatory guanine nucleotide binding protein subunit 1 mutation in two siblings with pseudohypoparathyroidism type 1a and mother with pseudopseudohypoparathyroidism.

Studies in a kindred with parathyroid carcinoma

The Role of Genomic Imprinting of Galpha in the Pathogenesis of Albright Hereditary Osteodystrophy

The alternative stimulatory G protein alpha-subunit XLalphas is a critical regulator of energy and glucose metabolism and sympathetic nerve activity in adult mice

The parathyroid/pituitary variant of multiple endocrine neoplasia type 1 usually has causes other than p27Kip1 mutations

The role of G-protein in matrix-mediated motility of highly and poorly invasive melanoma cells.

The role of GNAS and other imprinted genes in the development of obesity.

The role of tissue-specific imprinting as a source of phenotypic heterogeneity in human disease.

The stimulatory G protein alpha-subunit Gs alpha is imprinted in human thyroid glands: implications for thyroid function in pseudohypoparathyroidism types 1A and 1B.

The stimulatory G protein alpha-subunit gene: mutations and imprinting lead to complex phenotypes

Thyrotrophin receptor signaling dependence of Braf-induced thyroid tumor initiation in mice

Tissue-specific imprinting of the G protein Gsalpha is associated with tissue-specific differences in histone methylation

Transgenic overexpression of the extra-large Gsα variant XLαs enhances Gsα-mediated responses in the mouse renal proximal tubule in vivo

Wnt/β-catenin signaling is differentially regulated by Gα proteins and contributes to fibrous dysplasia ⬇️