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Lista de obras de Javier Garzón

Activation of mu-opioid receptors transfers control of Galpha subunits to the regulator of G-protein signaling RGS9-2: role in receptor desensitization

artículo científico publicado en 2005

Administration of myr(+)-G(i2)alpha subunits prevents acute tolerance (tachyphylaxis) to mu-opioid effects in mice.

artículo científico publicado en 2001

Agonists determine the pattern of G-protein activation in mu-opioid receptor-mediated supraspinal analgesia.

artículo científico publicado en 2001

Antibodies and antisense oligodeoxynucleotides to mu-opioid receptors, selectively block the effects of mu-opioid agonists on intestinal transit and permeability in mice.

artículo científico publicado en 1999

Behavioral, neurochemical and morphological changes induced by the overexpression of munc18-1a in brain of mice: relevance to schizophrenia.

artículo científico publicado en 2013

Brain-specific Galphaz interacts with Src tyrosine kinase to regulate Mu-opioid receptor-NMDAR signaling pathway.

artículo científico publicado en 2009

Calcium/calmodulin-dependent protein kinase II supports morphine antinociceptive tolerance by phosphorylation of glycosylated phosducin-like protein.

artículo científico publicado en 2007

Changes in the number of dendritic spines in the medial preoptic area during a premature long-term social isolation in rats

artículo científico publicado en 1991

Differential modification of opiate receptor activity by arylsulfatase treatment

scientific article published on 01 May 1983

Direct association of Mu-opioid and NMDA glutamate receptors supports their cross-regulation: molecular implications for opioid tolerance.

artículo científico publicado en 2012

Dynorphin-(1-13): the effect of in vivo treatment on opiate bindings in vitro

artículo científico publicado en 1983

Effect of ICV pertussis toxin and N-ethylmaleimide on the levels of substance P and serotonin in brain and spinal cord of the rat

artículo científico publicado en 1990

Effect of human B-endorphin on the binding of different opiates to mouse brain membranes

artículo científico publicado en 1983

Effect of intrathecal injection of pertussis toxin on substance P, norepinephrine and serotonin contents in various neural structures of arthritic rats

artículo científico publicado en 1990

Effector antagonism by the regulators of G protein signalling (RGS) proteins causes desensitization of mu-opioid receptors in the CNS

artículo científico publicado en 2005

Expression of neural RGS-R7 and Gbeta5 Proteins in Response to Acute and Chronic Morphine.

artículo científico publicado en 2005

GPCRs promote the release of zinc ions mediated by nNOS/NO and the redox transducer RGSZ2 protein.

artículo científico publicado en 2012

GX/Z Is Regulated by μ But Not δ Opioid Receptors in the Stimulation of the Low Km GTPase Activity in Mouse Periaqueductal Grey Matter

artículo científico publicado el 1 de junio de 1997

HINT1 protein cooperates with cannabinoid 1 receptor to negatively regulate glutamate NMDA receptor activity

artículo científico publicado en 2013

In vivo modulation of G proteins and opioid receptor function by antisense oligodeoxynucleotides.

artículo científico publicado en 2000

Influence of Gz and Gi2 transducer proteins in the affinity of opioid agonists to mu receptors.

artículo científico publicado en 1998

Intrathecal pertussis toxin attenuates the morphine withdrawal syndrome in normal but not in arthritic rats.

artículo científico publicado en 1990

Intrinsic analgesic activity of human beta lipotropin in rats: comparison with other opioid peptides.

artículo científico publicado en 1981

Local changes in GTP-binding protein immunoreactivities in human epileptogenic neocortex.

artículo científico publicado en 1998

Mastoparan reduces the supraspinal analgesia mediated by mu/delta-opioid receptors in mice.

artículo científico publicado en 1994

Morphine induces endocytosis of neuronal mu-opioid receptors through the sustained transfer of Galpha subunits to RGSZ2 proteins

artículo científico publicado en 2007

Mu-opioid receptors transiently activate the Akt-nNOS pathway to produce sustained potentiation of PKC-mediated NMDAR-CaMKII signaling

artículo científico publicado en 2010

Myr+-Gi2 alpha and Go alpha subunits restore the efficacy of opioids, clonidine and neurotensin giving rise to antinociception in G-protein knock-down mice.

artículo científico publicado en 1999

NMDAR-nNOS generated zinc recruits PKCgamma to the HINT1-RGS17 complex bound to the C terminus of Mu-opioid receptors.

artículo científico publicado en 2008

NO-released zinc supports the simultaneous binding of Raf-1 and PKCγ cysteine-rich domains to HINT1 protein at the mu-opioid receptor.

artículo científico publicado en 2011

Nitric oxide and zinc-mediated protein assemblies involved in mu opioid receptor signaling.

artículo científico

Opiates as antidepressants.

artículo científico publicado en 2009

Pertussis toxin differentially reduces the efficacy of opioids to produce supraspinal analgesia in the mouse

scientific article published on 01 August 1988

Portentiation of the analgesia induced in rats by morphine or [D-Ala2]-met-enkephalinamide after inhibition of brain type B monoamine oxidase: the role of phenylethylamine

artículo científico publicado en 1980

RGS-Rz and RGS9-2 proteins control mu-opioid receptor desensitisation in CNS: the role of activated Galphaz subunits

artículo científico publicado en 2005

RGS14 prevents morphine from internalizing Mu-opioid receptors in periaqueductal gray neurons.

artículo científico publicado en 2007

RGS9 proteins facilitate acute tolerance to mu-opioid effects

artículo científico publicado en 2001

RGSZ2 binds to the neural nitric oxide synthase PDZ domain to regulate mu-opioid receptor-mediated potentiation of the N-methyl-D-aspartate receptor-calmodulin-dependent protein kinase II pathway.

artículo científico publicado en 2011

SUMO-SIM interactions regulate the activity of RGSZ2 proteins

artículo científico publicado en 2011

Sensitivity to μ‐opioid receptor‐mediated anti‐nociception is determined by cross‐regulation between μ‐ and δ‐opioid receptors at supraspinal level

artículo científico publicado el 1 de mayo de 2012

Stimulation of mu- and delta-opioid receptors enhances phosphoinositide metabolism in mouse spinal cord: evidence for subtypes of delta-receptors.

artículo científico publicado en 1999

Sumoylated RGS-Rz proteins act as scaffolds for Mu-opioid receptors and G-protein complexes in mouse brain.

artículo científico publicado en 2006

Supersensitivity to mu-opioid receptor-mediated inhibition of the adenylyl cyclase pathway involves pertussis toxin-resistant Galpha protein subunits

scientific journal article

The GBeta5 subunit that associates with the R7 subfamily of RGS proteins regulates mu-opioid effects.

artículo científico publicado en 2003

The delta2-opioid receptor subtype stimulates phosphoinositide metabolism in mouse periaqueductal gray matter.

artículo científico publicado en 1998

The histidine triad nucleotide-binding protein 1 supports mu-opioid receptor-glutamate NMDA receptor cross-regulation

artículo científico publicado en 2010

The mu-opioid receptor and the NMDA receptor associate in PAG neurons: implications in pain control.

artículo científico publicado en 2011

The plasticity of the association between mu-opioid receptor and glutamate ionotropic receptor N in opioid analgesic tolerance and neuropathic pain.

artículo científico

Transport of CSF antibodies to Galpha subunits across neural membranes requires binding to the target protein and protein kinase C activity.

artículo científico publicado en 1999

Use of selective antagonists and antisense oligonucleotides to evaluate the mechanisms of BUBU antinociception

artículo científico publicado en 1999