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Lista de obras de Janet Dawson

A natural ligand for the orphan receptor GPR15 modulates lymphocyte recruitment to epithelia

artículo científico publicado en 2017

Angiogenesis inhibition by the novel VEGF receptor tyrosine kinase inhibitor, PTK787/ZK222584, causes significant anti-arthritic effects in models of rheumatoid arthritis

artículo científico publicado en 2004

Anti-hyperalgesic activity of the cox-2 inhibitor lumiracoxib in a model of bone cancer pain in the rat.

artículo científico publicado en 2004

CYCLOSPORIN A INHIBITS THE IN VIVO PRODUCTION OF INTERLEUKIN-1β AND TUMOUR NECROSIS FACTOR α, BUT NOT INTERLEUKIN-6, BY A T-CELL-INDEPENDENT MECHANISM

artículo científico publicado en 1996

Deficiency of MALT1 paracaspase activity results in unbalanced regulatory and effector T and B cell responses leading to multiorgan inflammation

artículo científico publicado en 2015

Design and synthesis of potent and orally active GPR4 antagonists with modulatory effects on nociception, inflammation, and angiogenesis

artículo científico publicado en 2017

Discovery of LOU064 (Remibrutinib), a Potent and Highly Selective Covalent Inhibitor of Bruton's Tyrosine Kinase

artículo científico publicado en 2020

Effect of cyclosporine and some derivatives on chronic rejection

scientific article published on 01 December 1996

Effects of soluble interleukin-1 type II receptor on rabbit antigen-induced arthritis: clinical, biochemical and histological assessment

artículo científico publicado en 1999

Feasibility and physiological relevance of designing highly potent aminopeptidase-sparing leukotriene A4 hydrolase inhibitors.

artículo científico publicado en 2017

GPR91 deficiency exacerbates allergic contact dermatitis while reducing arthritic disease in mice

artículo científico publicado en 2016

GPR91 senses extracellular succinate released from inflammatory macrophages and exacerbates rheumatoid arthritis.

scientific article published on August 2016

High-resolution three-dimensional magnetic resonance imaging for the investigation of knee joint damage during the time course of antigen-induced arthritis in rabbits

scientific article published on 01 January 1999

Improved lymphocyte function-associated antigen-1 (LFA-1) inhibition by statin derivatives: molecular basis determined by x-ray analysis and monitoring of LFA-1 conformational changes in vitro and ex vivo

artículo científico publicado en 2004

In vivo and in vitro SAR of tetracyclic MAPKAP-K2 (MK2) inhibitors. Part II

artículo científico publicado en 2010

Inhibition of the Inositol Kinase Itpkb Augments Calcium Signaling in Lymphocytes and Reveals a Novel Strategy to Treat Autoimmune Disease

artículo científico publicado en 2015

Lymphocyte migration in the mouse. I. Time course of cell accumulation and the effect of antigen sensitisation and challenge in a murine model of chronic inflammation

artículo científico publicado el 1 de marzo de 1992

Lymphocyte migration in the mouse. II. Differential B and T-lymphocyte migration into a site of chronic inflammation

artículo científico publicado el 1 de marzo de 1992

Macrophage infiltration into the rat knee detected by MRI in a model of antigen-induced arthritis

artículo científico publicado en 2003

Neutropenia with Impaired Immune Response to Streptococcus pneumoniae in Ceramide Kinase-Deficient Mice

artículo científico publicado en 2008

Non-invasive imaging demonstrates clinical features of ankylosing spondylitis in a rat adjuvant model: a case study

artículo científico publicado en 2016

Nondepleting anti-CD4 and soluble interleukin-1 receptor prevent autoimmune destruction of syngeneic islet grafts in diabetic NOD mice

artículo científico publicado en 2002

Preclinical pharmacology of lumiracoxib: a novel selective inhibitor of cyclooxygenase-2.

artículo científico publicado en 2005

Preclinical pharmacology of robenacoxib: a novel selective inhibitor of cyclooxygenase-2.

artículo científico publicado en 2009

Serum Amyloid A (apoSAA) Expression Is Up-Regulated in Rheumatoid Arthritis and Induces Transcription of Matrix Metalloproteinases

artículo científico publicado en 2001

Synthesis and Biological Evaluation of New Triazolo- and Imidazolopyridine RORγt Inverse Agonists

artículo científico publicado en 2016

Synthesis of 4-(8-benzo[1,2,5]oxadiazol-5-yl-[1,7]naphthyridine-6-yl)-benzoic acid: a potent and selective phosphodiesterase type 4D inhibitor

artículo científico publicado en 2002

Targeting interleukin-4 to the arthritic joint

artículo científico publicado en 2020

Targeting monocyte chemoattractant protein-1 signalling in disease

artículo científico publicado en 2003

The critical role of kinase activity of interleukin-1 receptor-associated kinase 4 in animal models of joint inflammation

artículo científico publicado en 2009

Transient targeting of phosphoinositide 3-kinase acts as a roadblock in mast cells' route to allergy

artículo científico publicado en 2013