Lista de obras - Paola Spessotto - Dominio Público Uruguay

Abrogation of EMILIN1-β1 integrin interaction promotes experimental colitis and colon carcinogenesis

scientific article published on 31 August 2019

Actin-dependent tumour cell adhesion after short-term exposure to the antimetastasis ruthenium complex NAMI-A.

artículo científico publicado en 2004

An EMILIN1-negative microenvironment promotes tumor cell proliferation and lymph node invasion.

artículo científico publicado en 2012

An alternative role of C1q in cell migration and tissue remodeling: contribution to trophoblast invasion and placental development

artículo científico publicado en 2010

Antigene effect in K562 cells of a PEG-conjugated triplex-forming oligonucleotide targeted to the bcr/abl oncogene

artículo científico publicado en 2002

Blood-derived human osteoclast resorption activity is impaired by Hyaluronan-CD44 engagement via a p38-dependent mechanism.

artículo científico publicado en 2011

Common biological phenotypes characterize the acquisition of platinum-resistance in epithelial ovarian cancer cells.

artículo científico publicado en 2017

Diagnostic Exome Sequencing Identifies a Novel Gene, EMILIN1, Associated with Autosomal-Dominant Hereditary Connective Tissue Disease

scientific journal article

Differential Expression of IRS-1 and IRS-2 in Uterine Leiomyosarcomas with Distinct Oncogenic Phenotypes: Lack of Correlation with Downstream Signaling Events.

artículo científico publicado en 2002

Distribution of PG-M/versican variants in human tissues and de novo expression of isoform V3 upon endothelial cell activation, migration, and neoangiogenesis in vitro

artículo científico publicado en 2002

EMILIN1-α4/α9 integrin interaction inhibits dermal fibroblast and keratinocyte proliferation.

artículo científico publicado en 2011

Emilin1 deficiency causes structural and functional defects of lymphatic vasculature.

artículo científico publicado en 2008

Evaluation of neoangiogenesis in locally advanced gastric cancer before and after neoadjuvant radiochemotherapy by probe confocal laser endomicroscopy (PCLE)

artículo científico publicado en 2019

Expression profiles in malignant fibrous histiocytomas: Clues for differentiating ‘spindle cell’ and ‘pleomorphic’ subtypes

artículo científico publicado en 2008

Functional osteoclastogenesis: the baseline variability in blood donor precursors is not associated with age and gender

artículo científico publicado en 2015

Human eosinophil peroxidase enhances tumor necrosis factor and hydrogen peroxide release by human monocyte-derived macrophages

artículo científico publicado en 1995

Human neutrophils specifically interact with human monocyte-derived macrophage monolayers

artículo científico publicado en 2000

Hyaluronan-CD44 interaction hampers migration of osteoclast-like cells by down-regulating MMP-9.

artículo científico publicado en 2002

Identification of Domains Responsible for von Willebrand Factor Type VI Collagen Interaction Mediating Platelet Adhesion under High Flow

artículo científico publicado en 1999

Identification of elastase in human eosinophils: immunolocalization, isolation, and partial characterization.

artículo científico publicado en 1992

Inhibition of B16 melanoma metastases with the ruthenium complex imidazolium trans-imidazoledimethylsulfoxide-tetrachlororuthenate and down-regulation of tumor cell invasion.

artículo científico publicado en 2005

Integrin binding site within the gC1q domain orchestrates EMILIN-1-induced lymphangiogenesis

artículo científico publicado en 2018

Laminin-332 (Laminin-5) is the major motility ligand for B cell chronic lymphocytic leukemia.

artículo científico publicado en 2007

Local inhibition of elastase reduces EMILIN1 cleavage reactivating lymphatic vessel function in a mouse lymphoedema model

artículo científico publicado en 2016

Loss of Multimerin-2 and EMILIN-2 Expression in Gastric Cancer Associate with Altered Angiogenesis

scientific article published in 2018

MFSD2A is a novel lung tumor suppressor gene modulating cell cycle and matrix attachment

artículo científico publicado en 2010

MMP-13 stimulates osteoclast differentiation and activation in tumour breast bone metastases.

artículo científico publicado en 2011

Multiplex staining depicts the immune infiltrate in colitis-induced colon cancer model

scientific article published on 02 September 2019

Multispectral imaging technology: Visualize, analyze, phenotyping, and quantify immune cells in situ

artículo científico publicado en 2020

Neutrophil elastase cleavage of the gC1q domain impairs the EMILIN1-α4β1 integrin interaction, cell adhesion and anti-proliferative activity

artículo científico publicado en 2017

Neutrophil elastase-dependent cleavage compromises the tumor suppressor role of EMILIN1.

artículo científico publicado en 2014

Preferential locomotion of leukemic cells towards laminin isoforms 8 and 10.

artículo científico publicado en 2003

Probe-based confocal laser endomicroscopy (pCLE) is a suitable method for extrapulmonary high grade neuroendocrine rectal carcinoma (HGNEC) evaluation

artículo científico publicado en 2019

Probe-based confocal laser endomicroscopy for in vivo evaluation of the tumor vasculature in gastric and rectal carcinomas.

artículo científico publicado en 2017

Role of E2F1-cyclin E1-cyclin E2 circuit in human coronary smooth muscle cell proliferation and therapeutic potential of its downregulation by siRNAs.

artículo científico publicado en 2009

Role of Extracellular Matrix in Gastrointestinal Cancer-Associated Angiogenesis ⬇️

artículo científico publicado en 2020

Serum- and glucocorticoid- inducible kinase 2, SGK2, is a novel autophagy regulator and modulates platinum drugs response in cancer cells

artículo científico publicado en 2020

The EMILIN/Multimerin family.

artículo científico publicado en 2011

The Probe Based Confocal Laser Endomicroscopy (pCLE) in Locally Advanced Gastric Cancer: A Powerful Technique for Real-Time Analysis of Vasculature

scientific article published on 13 June 2019

The angiostatic molecule Multimerin 2 is processed by MMP-9 to allow sprouting angiogenesis

artículo científico publicado en 2017

The extracellular matrix protein EMILIN1 silences the RAS-ERK pathway via α4β1 integrin and decreases tumor cell growth.

artículo científico publicado en 2017

The role of molecular and imaging biomarkers in the evaluation of inflammation in oncology

artículo científico publicado en 2020

The solution structure of EMILIN1 globular C1q domain reveals a disordered insertion necessary for interaction with the alpha4beta1 integrin

scientific journal article

The α4β1/EMILIN1 interaction discloses a novel and unique integrin-ligand type of engagement

artículo científico publicado en 2017

Tumor microenvironment in diffuse large B-cell lymphoma: Matrixmetalloproteinases activation is mediated by osteopontin overexpression

artículo científico publicado en 2015

VE-cadherin is a critical molecule for trophoblast?endothelial cell interaction in decidual spiral arteries

artículo científico publicado en 2004

Vascular PG-M/versican variants promote platelet adhesion at low shear rates and cooperate with collagens to induce aggregation

artículo científico publicado en 2002

beta 1 Integrin-dependent cell adhesion to EMILIN-1 is mediated by the gC1q domain.

artículo científico publicado en 2002

p27(Kip1)-stathmin interaction influences sarcoma cell migration and invasion

scientific journal article

Lista de obras de Paola Spessotto

Abrogation of EMILIN1-β1 integrin interaction promotes experimental colitis and colon carcinogenesis

Actin-dependent tumour cell adhesion after short-term exposure to the antimetastasis ruthenium complex NAMI-A.

An EMILIN1-negative microenvironment promotes tumor cell proliferation and lymph node invasion.

An alternative role of C1q in cell migration and tissue remodeling: contribution to trophoblast invasion and placental development

Antigene effect in K562 cells of a PEG-conjugated triplex-forming oligonucleotide targeted to the bcr/abl oncogene

Blood-derived human osteoclast resorption activity is impaired by Hyaluronan-CD44 engagement via a p38-dependent mechanism.

Common biological phenotypes characterize the acquisition of platinum-resistance in epithelial ovarian cancer cells.

Diagnostic Exome Sequencing Identifies a Novel Gene, EMILIN1, Associated with Autosomal-Dominant Hereditary Connective Tissue Disease

Differential Expression of IRS-1 and IRS-2 in Uterine Leiomyosarcomas with Distinct Oncogenic Phenotypes: Lack of Correlation with Downstream Signaling Events.

Distribution of PG-M/versican variants in human tissues and de novo expression of isoform V3 upon endothelial cell activation, migration, and neoangiogenesis in vitro

EMILIN1-α4/α9 integrin interaction inhibits dermal fibroblast and keratinocyte proliferation.

Emilin1 deficiency causes structural and functional defects of lymphatic vasculature.

Evaluation of neoangiogenesis in locally advanced gastric cancer before and after neoadjuvant radiochemotherapy by probe confocal laser endomicroscopy (PCLE)

Expression profiles in malignant fibrous histiocytomas: Clues for differentiating ‘spindle cell’ and ‘pleomorphic’ subtypes

Functional osteoclastogenesis: the baseline variability in blood donor precursors is not associated with age and gender

Human eosinophil peroxidase enhances tumor necrosis factor and hydrogen peroxide release by human monocyte-derived macrophages

Human neutrophils specifically interact with human monocyte-derived macrophage monolayers

Hyaluronan-CD44 interaction hampers migration of osteoclast-like cells by down-regulating MMP-9.

Identification of Domains Responsible for von Willebrand Factor Type VI Collagen Interaction Mediating Platelet Adhesion under High Flow

Identification of elastase in human eosinophils: immunolocalization, isolation, and partial characterization.

Inhibition of B16 melanoma metastases with the ruthenium complex imidazolium trans-imidazoledimethylsulfoxide-tetrachlororuthenate and down-regulation of tumor cell invasion.

Integrin binding site within the gC1q domain orchestrates EMILIN-1-induced lymphangiogenesis

Laminin-332 (Laminin-5) is the major motility ligand for B cell chronic lymphocytic leukemia.

Local inhibition of elastase reduces EMILIN1 cleavage reactivating lymphatic vessel function in a mouse lymphoedema model

Loss of Multimerin-2 and EMILIN-2 Expression in Gastric Cancer Associate with Altered Angiogenesis

MFSD2A is a novel lung tumor suppressor gene modulating cell cycle and matrix attachment

MMP-13 stimulates osteoclast differentiation and activation in tumour breast bone metastases.

Multiplex staining depicts the immune infiltrate in colitis-induced colon cancer model

Multispectral imaging technology: Visualize, analyze, phenotyping, and quantify immune cells in situ

Neutrophil elastase cleavage of the gC1q domain impairs the EMILIN1-α4β1 integrin interaction, cell adhesion and anti-proliferative activity

Neutrophil elastase-dependent cleavage compromises the tumor suppressor role of EMILIN1.

Preferential locomotion of leukemic cells towards laminin isoforms 8 and 10.

Probe-based confocal laser endomicroscopy (pCLE) is a suitable method for extrapulmonary high grade neuroendocrine rectal carcinoma (HGNEC) evaluation

Probe-based confocal laser endomicroscopy for in vivo evaluation of the tumor vasculature in gastric and rectal carcinomas.

Role of E2F1-cyclin E1-cyclin E2 circuit in human coronary smooth muscle cell proliferation and therapeutic potential of its downregulation by siRNAs.

Role of Extracellular Matrix in Gastrointestinal Cancer-Associated Angiogenesis ⬇️

Serum- and glucocorticoid- inducible kinase 2, SGK2, is a novel autophagy regulator and modulates platinum drugs response in cancer cells

The EMILIN/Multimerin family.

The Probe Based Confocal Laser Endomicroscopy (pCLE) in Locally Advanced Gastric Cancer: A Powerful Technique for Real-Time Analysis of Vasculature

The angiostatic molecule Multimerin 2 is processed by MMP-9 to allow sprouting angiogenesis

The extracellular matrix protein EMILIN1 silences the RAS-ERK pathway via α4β1 integrin and decreases tumor cell growth.

The role of molecular and imaging biomarkers in the evaluation of inflammation in oncology

The solution structure of EMILIN1 globular C1q domain reveals a disordered insertion necessary for interaction with the alpha4beta1 integrin

The α4β1/EMILIN1 interaction discloses a novel and unique integrin-ligand type of engagement

Tumor microenvironment in diffuse large B-cell lymphoma: Matrixmetalloproteinases activation is mediated by osteopontin overexpression

VE-cadherin is a critical molecule for trophoblast?endothelial cell interaction in decidual spiral arteries

Vascular PG-M/versican variants promote platelet adhesion at low shear rates and cooperate with collagens to induce aggregation

beta 1 Integrin-dependent cell adhesion to EMILIN-1 is mediated by the gC1q domain.

p27(Kip1)-stathmin interaction influences sarcoma cell migration and invasion