Lista de obras - Thomas Hellmark - Dominio Público Uruguay

A 59-kD renal antigen as a new target for rapidly progressive glomerulonephritis

artículo científico publicado en 2007

A Case of Alport Syndrome with Posttransplant Antiglomerular Basement Membrane Disease despite Negative Antiglomerular Basement Membrane Antibodies by EIA Treated with Plasmapheresis and Intravenous Immunoglobulin

artículo científico publicado en 2013

A nephritogenic peptide induces intermolecular epitope spreading on collagen IV in experimental autoimmune glomerulonephritis.

artículo científico publicado en 2006

Anti-GBM antibodies in Goodpasture syndrome; anatomy of an epitope

artículo científico publicado en 1997

Anti-glomerular basement membrane disease: an update on subgroups, pathogenesis and therapies

artículo científico publicado en 2019

Anti-glomerular basement membrane nephritis and bullous pemphigoid caused by distinct anti-alpha 3(IV)NC1 and anti-BP180 antibodies in a patient with Crohn's disease

artículo científico publicado en 2002

Anti-type IV collagen antibodies in Goodpasture syndrome

scientific article published on 01 January 1994

Antigen and epitope specificity of anti-glomerular basement membrane antibodies in patients with goodpasture disease with or without anti-neutrophil cytoplasmic antibodies

artículo científico publicado en 2007

Autoantibodies against components of renal basement membrane.

artículo científico publicado en 1997

Autoimmune kidney diseases

artículo científico publicado en 2009

BPI-ANCA Provides Additional Clinical Information to Anti-Pseudomonas Serology: Results from a Cohort of 117 Swedish Cystic Fibrosis Patients

artículo científico publicado en 2015

Binding and inhibition of myeloperoxidase (MPO): a major function of ceruloplasmin?

scientific article published on 01 April 1997

Bone marrow eosinophils in plasma cell disorders

artículo científico publicado en 2018

CD81 and CD48 show different expression on blood eosinophils in systemic sclerosis: new markers for disease and pulmonary inflammation?

artículo científico publicado en 2015

Characterization of anti-GBM antibodies involved in Goodpasture's syndrome

artículo científico publicado en 1994

Circulating microRNA expression pattern separates patients with anti-neutrophil cytoplasmic antibody associated vasculitis from healthy controls.

artículo científico publicado en 2015

Circulating microRNA expression profiles associated with systemic lupus erythematosus.

artículo científico publicado en 2013

Comparison of anti-GBM antibodies in sera with or without ANCA.

artículo científico publicado en 1997

Comparison of characteristics of natural autoantibodies against myeloperoxidase and anti-myeloperoxidase autoantibodies from patients with microscopic polyangiitis

artículo científico publicado en 2011

Decreased neutrophil apoptosis in quiescent ANCA-associated systemic vasculitis

artículo científico publicado en 2012

Diagnosis and classification of Goodpasture's disease (anti-GBM).

artículo científico

Different fractions of human serum glycoproteins bind galectin-1 or galectin-8, and their ratio may provide a refined biomarker for pathophysiological conditions in cancer and inflammatory disease

scientific article published on 17 January 2012

Elevated neutrophil membrane expression of proteinase 3 is dependent upon CD177 expression

artículo científico publicado en 2010

Eosinophils in anti-neutrophil cytoplasmic antibody associated vasculitis

Epitope mapping of anti-PR3 antibodies using chimeric human/mouse PR3 recombinant proteins

artículo científico publicado en 2004

Epitope mapping of anti-glomerular basement membrane (GBM) antibodies with synthetic peptides

artículo científico publicado en 1996

Epitope shift of proteinase-3 anti-neutrophil cytoplasmic antibodies in patients with small vessel vasculitis

artículo científico publicado en 2010

Epitope spreading and autoimmune glomerulonephritis in rats induced by a T cell epitope of Goodpasture's antigen

artículo científico publicado en 2005

Factors Associated With Pathogenicity of Anti-Glomerular Basal Membrane Antibodies: A Case Report.

artículo científico publicado en 2016

Galectin-8 in IgA nephritis: decreased binding of IgA by galectin-8 affinity chromatography and associated increased binding in non-IgA serum glycoproteins.

artículo científico publicado en 2011

Goodpasture disease. Characterization of a single conformational epitope as the target of pathogenic autoantibodies.

artículo científico publicado en 1999

Identification of a clinically relevant immunodominant region of collagen IV in Goodpasture disease.

artículo científico publicado en 1999

Identification of noncollagenous sites encoding specific interactions and quaternary assembly of alpha 3 alpha 4 alpha 5(IV) collagen: implications for Alport gene therapy.

artículo científico publicado en 2008

IgG glycan hydrolysis attenuates ANCA-mediated glomerulonephritis.

artículo científico publicado en 2010

Immunodominant epitopes of alpha3(IV)NC1 induce autoimmune glomerulonephritis in rats

artículo científico publicado en 2003

Impaired phagocytosis and reactive oxygen species production in phagocytes is associated with systemic vasculitis.

artículo científico publicado en 2016

Increased Frequencies of Switched Memory B Cells and Plasmablasts in Peripheral Blood from Patients with ANCA-Associated Vasculitis

artículo científico publicado en 2020

Increased levels of neutrophil extracellular trap remnants in the circulation of patients with small vessel vasculitis, but an inverse correlation to anti-neutrophil cytoplasmic antibodies during remission

artículo científico publicado en 2015

Increased monocyte transcription of the proteinase 3 gene in small vessel vasculitis

artículo científico publicado en 2005

Increased neutrophil membrane expression and plasma level of proteinase 3 in systemic vasculitis are not a consequence of the - 564 A/G promotor polymorphism

artículo científico publicado en 2006

Increased platelet activation occurs in cystic fibrosis patients and correlates to clinical status

artículo científico publicado en 2017

Integrin alpha3beta1, a novel receptor for alpha3(IV) noncollagenous domain and a trans-dominant Inhibitor for integrin alphavbeta3.

artículo científico publicado en 2006

Levels of epitope-specific autoantibodies correlate with renal damage in anti-GBM disease.

artículo científico publicado en 2009

Low production of reactive oxygen species in granulocytes is associated with organ damage in systemic lupus erythematosus

artículo científico publicado en 2014

Mapping of myeloperoxidase epitopes recognized by MPO-ANCA using human-mouse MPO chimers

artículo científico publicado en 2006

Molecular mapping of the Goodpasture's epitope for glomerulonephritis

artículo científico publicado en 2005

Multicenter prospective study of the humoral autoimmune response in bullous pemphigoid

artículo científico publicado en 2008

Muscle mass and plasma myostatin after exercise training: a substudy of Renal Exercise (RENEXC)-a randomized controlled trial

scientific article published on 17 December 2019

Natural anti-GBM antibodies from normal human sera recognize alpha3(IV)NC1 restrictively and recognize the same epitopes as anti-GBM antibodies from patients with anti-GBM disease

scientific article published on 06 June 2007

Natural autoantibodies to myeloperoxidase, proteinase 3, and the glomerular basement membrane are present in normal individuals

artículo científico publicado en 2010

Neutrophil-Derived Proteinase 3 Induces Kallikrein-Independent Release of a Novel Vasoactive Kinin

article published in 2009

Neutrophils from vasculitis patients exhibit an increased propensity for activation by anti-neutrophil cytoplasmic antibodies.

artículo científico publicado en 2014

Patients with Goodpasture's disease have two normal COL4A3 alleles encoding the NC1 domain of the type IV collagen alpha 3 chain

artículo científico publicado en 2004

Persons' Experiences of Suffering from Nephrotic Syndrome

scientific article published on 19 November 2019

Phagocyte function decreases after high-dose treatment with melphalan and autologous stem cell transplantation in patients with multiple myeloma

artículo científico publicado en 2016

Phagocytosis of apoptotic cells by macrophages in anti-neutrophil cytoplasmic antibody-associated systemic vasculitis

artículo científico publicado en 2012

Phenotypic Characterization of Circulating CD4+ T Cells in ANCA-Associated Vasculitis.

artículo científico publicado en 2018

Point mutations of single amino acids abolish ability of alpha3 NC1 domain to elicit experimental autoimmune glomerulonephritis in rats

artículo científico publicado en 2003

Proteinase 3 and CD177 are expressed on the plasma membrane of the same subset of neutrophils

artículo científico publicado en 2006

Pseudomonas aeruginosa in cystic fibrosis: pyocyanin negative strains are associated with BPI-ANCA and progressive lung disease.

artículo científico publicado en 2011

RNAi as a Tool to Study Virulence in the Pathogenic Yeast Candida glabrata

artículo científico publicado en 2019

Rats and mice immunised with chimeric human/mouse proteinase 3 produce autoantibodies to mouse Pr3 and rat granulocytes

artículo científico publicado en 2007

Routinely used immunoassays do not detect circulating anti-GBM antibodies against native NC1 hexamer and EA epitope of the α3 chain of type IV collagen

scientific article published on 02 May 2018

Serum from patients with systemic vasculitis induces alternatively activated macrophage M2c polarization.

artículo científico publicado en 2014

Spike-Dependent Opsonization Indicates Both Dose-Dependent Inhibition of Phagocytosis and That Non-Neutralizing Antibodies Can Confer Protection to SARS-CoV-2

scientific article published on 14 January 2022

Successful treatment of experimental glomerulonephritis with IdeS and EndoS, IgG-degrading streptococcal enzymes

artículo científico publicado en 2010

The - 564 A/G polymorphism in the promoter region of the proteinase 3 gene associated with Wegener's granulomatosis does not increase the promoter activity

artículo científico publicado en 2004

The prognostic significance in Goodpasture's disease of specificity, titre and affinity of anti-glomerular-basement-membrane antibodies

scientific article published on 01 January 2003

Twelve months of exercise training did not halt abdominal aortic calcification in patients with CKD - a sub-study of RENEXC-a randomized controlled trial

artículo científico publicado en 2020

Lista de obras de Thomas Hellmark

A 59-kD renal antigen as a new target for rapidly progressive glomerulonephritis

A Case of Alport Syndrome with Posttransplant Antiglomerular Basement Membrane Disease despite Negative Antiglomerular Basement Membrane Antibodies by EIA Treated with Plasmapheresis and Intravenous Immunoglobulin

A nephritogenic peptide induces intermolecular epitope spreading on collagen IV in experimental autoimmune glomerulonephritis.

Anti-GBM antibodies in Goodpasture syndrome; anatomy of an epitope

Anti-glomerular basement membrane disease: an update on subgroups, pathogenesis and therapies

Anti-glomerular basement membrane nephritis and bullous pemphigoid caused by distinct anti-alpha 3(IV)NC1 and anti-BP180 antibodies in a patient with Crohn's disease

Anti-type IV collagen antibodies in Goodpasture syndrome

Antigen and epitope specificity of anti-glomerular basement membrane antibodies in patients with goodpasture disease with or without anti-neutrophil cytoplasmic antibodies

Autoantibodies against components of renal basement membrane.

Autoimmune kidney diseases

BPI-ANCA Provides Additional Clinical Information to Anti-Pseudomonas Serology: Results from a Cohort of 117 Swedish Cystic Fibrosis Patients

Binding and inhibition of myeloperoxidase (MPO): a major function of ceruloplasmin?

Bone marrow eosinophils in plasma cell disorders

CD81 and CD48 show different expression on blood eosinophils in systemic sclerosis: new markers for disease and pulmonary inflammation?

Characterization of anti-GBM antibodies involved in Goodpasture's syndrome

Circulating microRNA expression pattern separates patients with anti-neutrophil cytoplasmic antibody associated vasculitis from healthy controls.

Circulating microRNA expression profiles associated with systemic lupus erythematosus.

Comparison of anti-GBM antibodies in sera with or without ANCA.

Comparison of characteristics of natural autoantibodies against myeloperoxidase and anti-myeloperoxidase autoantibodies from patients with microscopic polyangiitis

Decreased neutrophil apoptosis in quiescent ANCA-associated systemic vasculitis

Diagnosis and classification of Goodpasture's disease (anti-GBM).

Different fractions of human serum glycoproteins bind galectin-1 or galectin-8, and their ratio may provide a refined biomarker for pathophysiological conditions in cancer and inflammatory disease

Elevated neutrophil membrane expression of proteinase 3 is dependent upon CD177 expression

Eosinophils in anti-neutrophil cytoplasmic antibody associated vasculitis

Epitope mapping of anti-PR3 antibodies using chimeric human/mouse PR3 recombinant proteins

Epitope mapping of anti-glomerular basement membrane (GBM) antibodies with synthetic peptides

Epitope shift of proteinase-3 anti-neutrophil cytoplasmic antibodies in patients with small vessel vasculitis

Epitope spreading and autoimmune glomerulonephritis in rats induced by a T cell epitope of Goodpasture's antigen

Factors Associated With Pathogenicity of Anti-Glomerular Basal Membrane Antibodies: A Case Report.

Galectin-8 in IgA nephritis: decreased binding of IgA by galectin-8 affinity chromatography and associated increased binding in non-IgA serum glycoproteins.

Goodpasture disease. Characterization of a single conformational epitope as the target of pathogenic autoantibodies.

Identification of a clinically relevant immunodominant region of collagen IV in Goodpasture disease.

Identification of noncollagenous sites encoding specific interactions and quaternary assembly of alpha 3 alpha 4 alpha 5(IV) collagen: implications for Alport gene therapy.

IgG glycan hydrolysis attenuates ANCA-mediated glomerulonephritis.

Immunodominant epitopes of alpha3(IV)NC1 induce autoimmune glomerulonephritis in rats

Impaired phagocytosis and reactive oxygen species production in phagocytes is associated with systemic vasculitis.

Increased Frequencies of Switched Memory B Cells and Plasmablasts in Peripheral Blood from Patients with ANCA-Associated Vasculitis

Increased levels of neutrophil extracellular trap remnants in the circulation of patients with small vessel vasculitis, but an inverse correlation to anti-neutrophil cytoplasmic antibodies during remission

Increased monocyte transcription of the proteinase 3 gene in small vessel vasculitis

Increased neutrophil membrane expression and plasma level of proteinase 3 in systemic vasculitis are not a consequence of the - 564 A/G promotor polymorphism

Increased platelet activation occurs in cystic fibrosis patients and correlates to clinical status

Integrin alpha3beta1, a novel receptor for alpha3(IV) noncollagenous domain and a trans-dominant Inhibitor for integrin alphavbeta3.

Levels of epitope-specific autoantibodies correlate with renal damage in anti-GBM disease.

Low production of reactive oxygen species in granulocytes is associated with organ damage in systemic lupus erythematosus

Mapping of myeloperoxidase epitopes recognized by MPO-ANCA using human-mouse MPO chimers

Molecular mapping of the Goodpasture's epitope for glomerulonephritis

Multicenter prospective study of the humoral autoimmune response in bullous pemphigoid

Muscle mass and plasma myostatin after exercise training: a substudy of Renal Exercise (RENEXC)-a randomized controlled trial

Natural anti-GBM antibodies from normal human sera recognize alpha3(IV)NC1 restrictively and recognize the same epitopes as anti-GBM antibodies from patients with anti-GBM disease

Natural autoantibodies to myeloperoxidase, proteinase 3, and the glomerular basement membrane are present in normal individuals

Neutrophil-Derived Proteinase 3 Induces Kallikrein-Independent Release of a Novel Vasoactive Kinin

Neutrophils from vasculitis patients exhibit an increased propensity for activation by anti-neutrophil cytoplasmic antibodies.

Patients with Goodpasture's disease have two normal COL4A3 alleles encoding the NC1 domain of the type IV collagen alpha 3 chain

Persons' Experiences of Suffering from Nephrotic Syndrome

Phagocyte function decreases after high-dose treatment with melphalan and autologous stem cell transplantation in patients with multiple myeloma

Phagocytosis of apoptotic cells by macrophages in anti-neutrophil cytoplasmic antibody-associated systemic vasculitis

Phenotypic Characterization of Circulating CD4+ T Cells in ANCA-Associated Vasculitis.

Point mutations of single amino acids abolish ability of alpha3 NC1 domain to elicit experimental autoimmune glomerulonephritis in rats

Proteinase 3 and CD177 are expressed on the plasma membrane of the same subset of neutrophils

Pseudomonas aeruginosa in cystic fibrosis: pyocyanin negative strains are associated with BPI-ANCA and progressive lung disease.

RNAi as a Tool to Study Virulence in the Pathogenic Yeast Candida glabrata

Rats and mice immunised with chimeric human/mouse proteinase 3 produce autoantibodies to mouse Pr3 and rat granulocytes

Routinely used immunoassays do not detect circulating anti-GBM antibodies against native NC1 hexamer and EA epitope of the α3 chain of type IV collagen

Serum from patients with systemic vasculitis induces alternatively activated macrophage M2c polarization.

Spike-Dependent Opsonization Indicates Both Dose-Dependent Inhibition of Phagocytosis and That Non-Neutralizing Antibodies Can Confer Protection to SARS-CoV-2

Successful treatment of experimental glomerulonephritis with IdeS and EndoS, IgG-degrading streptococcal enzymes

The - 564 A/G polymorphism in the promoter region of the proteinase 3 gene associated with Wegener's granulomatosis does not increase the promoter activity

The prognostic significance in Goodpasture's disease of specificity, titre and affinity of anti-glomerular-basement-membrane antibodies

Twelve months of exercise training did not halt abdominal aortic calcification in patients with CKD - a sub-study of RENEXC-a randomized controlled trial