Lista de obras - Morgane Bomsel - Dominio Público Uruguay

A mucosally targeted subunit vaccine candidate eliciting HIV-1 transcytosis-blocking Abs.

scholarly article

A nonparametric procedure for defining a new humoral immunologic profile in a pilot study on HIV infected patients

artículo científico publicado en 2013

Alpha6beta1 integrin expressed by sperm is determinant in mouse fertilization

artículo científico publicado en 2007

B7 cosignal potentiates apoptosis of uninfected CD4+ T lymphocytic cell lines primed by HIV envelope proteins.

artículo científico publicado en 1999

Biochemical and functional characterization of three types of coated vesicles in bovine adrenocortical cells: implication in the intracellular traffic

scientific article published on 01 September 1988

Biochemical and immunological characterization of the plant-derived candidate human immunodeficiency virus type 1 mucosal vaccine CTB-MPR.

artículo científico publicado en 2008

Both lipid environment and pH are critical for determining physiological solution structure of 3-D-conserved epitopes of the HIV-1 gp41-MPER peptide P1.

artículo científico publicado en 2008

Both the Gsα and βγ subunits of the heterotrimeric G protein, Gs, control the sorting of the polymeric immunoglobulin receptor into transcytotic vesicles

artículo científico publicado en 1994

CD9 controls the formation of clusters that contain tetraspanins and the integrin alpha 6 beta 1, which are involved in human and mouse gamete fusion

artículo científico publicado en 2006

Calcitonin gene-related peptide induces HIV-1 proteasomal degradation in mucosal Langerhans cells.

artículo científico publicado en 2017

Calcitonin gene-related peptide inhibits Langerhans cell-mediated HIV-1 transmission

artículo científico publicado en 2013

Calcitonin gene-related peptide inhibits human immunodeficiency type 1 transmission by Langerhans cells via an autocrine/paracrine feedback mechanism.

artículo científico publicado en 2014

Cell-to-cell contact results in a selective translocation of maternal human immunodeficiency virus type 1 quasispecies across a trophoblastic barrier by both transcytosis and infection

artículo científico publicado en 2001

Characterization of Pseudomonas aeruginosa-induced MDCK cell injury: glycosylation-defective host cells are resistant to bacterial killing.

artículo científico publicado en 1995

Clustering in coated vesicles of polyunsaturated phospholipids segregated from plasma and Golgi membranes of adrenocortical cells

artículo científico publicado en 1987

Cyclic FEE peptide increases human gamete fusion and potentiates its RGD-induced inhibition.

artículo científico publicado en 2005

Cyclic QDE peptide increases fertilization rates and provides healthy pups in mouse

artículo científico publicado en 2008

Dictyostelium discoideum cells shed vesicles with associated DNA and vital stain Hoechst 33342 ⬇️

artículo científico publicado el 1 de mayo de 1998

Early events in HIV transmission through a human reconstructed vaginal mucosa

artículo científico publicado en 2008

Endocytosis in filter-grown Madin-Darby canine kidney cells.

artículo científico publicado en 1989

Evolution of cytoplasmic and membrane parameters during human oocyte maturation

artículo científico publicado en 1996

GP41-specific antibody blocks cell-free HIV type 1 transcytosis through human rectal mucosa and model colonic epithelium.

artículo científico publicado en 2010

Galactosyl ceramide expressed on dendritic cells can mediate HIV-1 transfer from monocyte derived dendritic cells to autologous T cells

article

Generation of HIV-1 Virus-Like Particles expressing different HIV-1 glycoproteins

artículo científico publicado en 2011

HIV-1 gp41-specific monoclonal mucosal IgAs derived from highly exposed but IgG-seronegative individuals block HIV-1 epithelial transcytosis and neutralize CD4(+) cell infection: an IgA gene and functional analysis

artículo científico publicado en 2009

HIV-1 reservoirs in urethral macrophages of patients under suppressive antiretroviral therapy

scientific article published on 04 February 2019

HIV-1 transmission in the male genital tract

artículo científico publicado en 2010

HIV-1-infected blood mononuclear cells form an integrin- and agrin-dependent viral synapse to induce efficient HIV-1 transcytosis across epithelial cell monolayer.

artículo científico publicado en 2005

High-level ability of secretory IgA to block HIV type 1 transcytosis: contrasting secretory IgA and IgG responses to glycoprotein 160.

artículo científico publicado en 1997

Human cytomegalovirus-encoded UL33 and UL78 heteromerize with host CCR5 and CXCR4 impairing their HIV coreceptor activity

article

Human cytomegalovirus-infected cells release extracellular vesicles that carry viral surface proteins

Human gamete fusion can bypass beta1 integrin requirement ⬇️

artículo científico publicado el 1 de marzo de 1998

Humoral immune responses by prime-boost heterologous route immunizations with CTB-MPR(649-684), a mucosal subunit HIV/AIDS vaccine candidate.

artículo científico publicado en 2006

Identification, Localization, and Quantification of HIV Reservoirs Using Microscopy

scientific article published on 28 September 2018

IgA Targeting Human Immunodeficiency Virus-1 Envelope gp41 Triggers Antibody-Dependent Cellular Cytotoxicity Cross-Clade and Cooperates with gp41-Specific IgG to Increase Cell Lysis.

artículo científico publicado en 2018

Immunization with HIV-1 gp41 Subunit Virosomes Induces Mucosal Antibodies Protecting Nonhuman Primates against Vaginal SHIV Challenges

article

In adrenocortical tissue, annexins II and VI are attached to clathrin coated vesicles in a calcium-independent manner1In memoriam: This last work as well as my scientific accomplishment are dedicated to the memory of Jeffries Wyman who was my best te

artículo científico publicado en 1998

Induction of HIV-blocking anti-CCR5 IgA in Peyers's patches without histopathological alterations.

scientific article published on 08 January 2014

Intracellular Neutralization of HIV Transcytosis across Tight Epithelial Barriers by Anti-HIV Envelope Protein dIgA or IgM

article

Isotype modulates epitope specificity, affinity, and antiviral activities of anti-HIV-1 human broadly neutralizing 2F5 antibody

artículo científico publicado en 2012

Ligand-blotting visualization of the LDL receptor in plasma membranes and in two classes of coated vesicles from adrenocortical cells

artículo científico publicado en 1985

Live Imaging of HIV-1 Transfer across T Cell Virological Synapse to Epithelial Cells that Promotes Stromal Macrophage Infection.

artículo científico publicado en 2018

Meeting of the apical and basolateral endocytic pathways of the Madin-Darby canine kidney cell in late endosomes.

artículo científico publicado en 1989

Membrane translocation of diphtheria toxin fragment A exploits early to late endosome trafficking machinery

artículo científico publicado en 1997

Microtubule- and motor-dependent fusion in vitro between apical and basolateral endocytic vesicles from MDCK cells

artículo científico publicado en 1990

Modifications of the human oocyte plasma membrane protein pattern during preovulatory maturation

artículo científico publicado en 1997

Mouse offspring after microinjection of heated spermatozoa

artículo científico publicado en 2001

Mucosal IgA in exposed, uninfected subjects: evidence for a role in protection against HIV infection

artículo científico publicado en 2001

Mucosal gatekeepers: Selecting HIV viruses for early infection

article

Natural mucosal antibodies reactive with first extracellular loop of CCR5 inhibit HIV-1 transport across human epithelial cells

artículo científico publicado en 2007

OA011-01. Early events of human immunodeficiency virus type 1 (HIV-1) ex vivo penetration in the foreskin mimicking HIV-1 sexual transmission

article

P11-20. HIV-1 gp41-specific mucosal IgAs from highly exposed but IgG seronegative women block HIV-1 epithelial transcytosis and neutralize CD4+ cell infection

article

P12-16. Biochemical and immunological characterization of the plant-derived candidate HIV-1 mucosal vaccine CTB-MPR.

artículo científico publicado en 2009

P19-02. High protection of female macaques from repeated intravaginal challenges with SHIV-162P3 upon mucosal vaccination with Gp41 subunits-virosomes

artículo científico publicado en 2009

Partial purification of the maturation-promoting factor MPF from unfertilized eggs of Xenopus laevis

artículo científico publicado en 1986

Peptide P5 (residues 628-683), comprising the entire membrane proximal region of HIV-1 gp41 and its calcium-binding site, is a potent inhibitor of HIV-1 infection

artículo científico publicado en 2008

Physical interaction of the HIV-1 Nef protein with beta-COP, a component of non-clathrin-coated vesicles essential for membrane traffic.

artículo científico publicado en 1994

Platelets from HIV-infected individuals on antiretroviral drug therapy with poor CD4+ T cell recovery can harbor replication-competent HIV despite viral suppression

artículo científico publicado en 2020

Possible role of both the alpha and beta gamma subunits of the heterotrimeric G protein, Gs, in transcytosis of the polymeric immunoglobulin receptor.

artículo científico publicado en 1993

Protecting the initial site of viral entry: an alternative HIV vaccine target ⬇️

artículo científico publicado el 1 de septiembre de 2011

Randomized Phase I: Safety, Immunogenicity and Mucosal Antiviral Activity in Young Healthy Women Vaccinated with HIV-1 Gp41 P1 Peptide on Virosomes

artículo científico publicado en 2013

Role of heterotrimeric G proteins in membrane traffic ⬇️

artículo científico publicado el 1 de diciembre de 1992

Secretory IgA specific for a conserved epitope on gp41 envelope glycoprotein inhibits epithelial transcytosis of HIV-1.

artículo científico publicado en 2001

Short Communication: Decreased Plasma Calcitonin Gene-Related Peptide as a Novel Biomarker for HIV-1 Disease Progression

artículo científico publicado en 2019

Sorting of plasma membrane proteins in epithelial cells ⬇️

artículo científico publicado el 1 de agosto de 1991

Specific lipid protein interactions characterize 3 populations of clathrin coated vesicles involved in the LDL receptor traffic

scientific article published on 01 June 1996

Stimulation of transcytosis of the polymeric immunoglobulin receptor by dimeric IgA.

artículo científico publicado en 1994

The CH1α domain of mucosal gp41 IgA contributes to antibody specificity and antiviral functions in HIV-1 highly exposed Sero-Negative individuals

artículo científico publicado en 2020

The HIV-1 viral synapse signals human foreskin keratinocytes to secrete thymic stromal lymphopoietin facilitating HIV-1 foreskin entry

artículo científico publicado en 2017

The Human Penis Is a Genuine Immunological Effector Site

artículo científico publicado en 2017

The adult penile urethra is a novel entry site for HIV-1 that preferentially targets resident urethral macrophages.

artículo científico publicado en 2012

The binding of HIV-1 gp41 membrane proximal domain to its mucosal receptor, galactosyl ceramide, is structure-dependent

article

The broadly neutralizing HIV-1 IgG 2F5 elicits gp41-specific antibody-dependent cell cytotoxicity in a FcγRI-dependent manner.

artículo científico publicado en 2011

The immunoglobulin CH1 constant region modulates antigen binding affinity and functional activities of the broadly neutralizing 2F5 HIV specific antibody

artículo científico publicado en 2010

Transcytosis-blocking abs elicited by an oligomeric immunogen based on the membrane proximal region of HIV-1 gp41 target non-neutralizing epitopes.

artículo científico publicado en 2008

Transfer of oocyte membrane fragments to fertilizing spermatozoa

artículo científico publicado en 2007

Unusual feeding behavior in wild great apes, a window to understand origins of self-medication in humans: Role of sociality and physiology on learning process ⬇️

artículo científico publicado el 23 de agosto de 2011

Virus like particle based strategy to elicit HIV-protective antibodies to the alpha-helic regions of gp41.

artículo científico publicado en 2012

Within 1 h, HIV-1 uses viral synapses to enter efficiently the inner, but not outer, foreskin mucosa and engages Langerhans–T cell conjugates

article

[Homology between antigenic determinants of bovine clathrin and clathrin from the brown alga Laminaria digitata]

artículo científico publicado en 1987

Lista de obras de Morgane Bomsel

A mucosally targeted subunit vaccine candidate eliciting HIV-1 transcytosis-blocking Abs.

A nonparametric procedure for defining a new humoral immunologic profile in a pilot study on HIV infected patients

Alpha6beta1 integrin expressed by sperm is determinant in mouse fertilization

B7 cosignal potentiates apoptosis of uninfected CD4+ T lymphocytic cell lines primed by HIV envelope proteins.

Biochemical and functional characterization of three types of coated vesicles in bovine adrenocortical cells: implication in the intracellular traffic

Biochemical and immunological characterization of the plant-derived candidate human immunodeficiency virus type 1 mucosal vaccine CTB-MPR.

Both lipid environment and pH are critical for determining physiological solution structure of 3-D-conserved epitopes of the HIV-1 gp41-MPER peptide P1.

Both the Gsα and βγ subunits of the heterotrimeric G protein, Gs, control the sorting of the polymeric immunoglobulin receptor into transcytotic vesicles

CD9 controls the formation of clusters that contain tetraspanins and the integrin alpha 6 beta 1, which are involved in human and mouse gamete fusion

Calcitonin gene-related peptide induces HIV-1 proteasomal degradation in mucosal Langerhans cells.

Calcitonin gene-related peptide inhibits Langerhans cell-mediated HIV-1 transmission

Calcitonin gene-related peptide inhibits human immunodeficiency type 1 transmission by Langerhans cells via an autocrine/paracrine feedback mechanism.

Cell-to-cell contact results in a selective translocation of maternal human immunodeficiency virus type 1 quasispecies across a trophoblastic barrier by both transcytosis and infection

Characterization of Pseudomonas aeruginosa-induced MDCK cell injury: glycosylation-defective host cells are resistant to bacterial killing.

Clustering in coated vesicles of polyunsaturated phospholipids segregated from plasma and Golgi membranes of adrenocortical cells

Cyclic FEE peptide increases human gamete fusion and potentiates its RGD-induced inhibition.

Cyclic QDE peptide increases fertilization rates and provides healthy pups in mouse

Dictyostelium discoideum cells shed vesicles with associated DNA and vital stain Hoechst 33342 ⬇️

Early events in HIV transmission through a human reconstructed vaginal mucosa

Endocytosis in filter-grown Madin-Darby canine kidney cells.

Evolution of cytoplasmic and membrane parameters during human oocyte maturation

GP41-specific antibody blocks cell-free HIV type 1 transcytosis through human rectal mucosa and model colonic epithelium.

Galactosyl ceramide expressed on dendritic cells can mediate HIV-1 transfer from monocyte derived dendritic cells to autologous T cells

Generation of HIV-1 Virus-Like Particles expressing different HIV-1 glycoproteins

HIV-1 gp41-specific monoclonal mucosal IgAs derived from highly exposed but IgG-seronegative individuals block HIV-1 epithelial transcytosis and neutralize CD4(+) cell infection: an IgA gene and functional analysis

HIV-1 reservoirs in urethral macrophages of patients under suppressive antiretroviral therapy

HIV-1 transmission in the male genital tract

HIV-1-infected blood mononuclear cells form an integrin- and agrin-dependent viral synapse to induce efficient HIV-1 transcytosis across epithelial cell monolayer.

High-level ability of secretory IgA to block HIV type 1 transcytosis: contrasting secretory IgA and IgG responses to glycoprotein 160.

Human cytomegalovirus-encoded UL33 and UL78 heteromerize with host CCR5 and CXCR4 impairing their HIV coreceptor activity

Human cytomegalovirus-infected cells release extracellular vesicles that carry viral surface proteins

Human gamete fusion can bypass beta1 integrin requirement ⬇️

Humoral immune responses by prime-boost heterologous route immunizations with CTB-MPR(649-684), a mucosal subunit HIV/AIDS vaccine candidate.

Identification, Localization, and Quantification of HIV Reservoirs Using Microscopy

IgA Targeting Human Immunodeficiency Virus-1 Envelope gp41 Triggers Antibody-Dependent Cellular Cytotoxicity Cross-Clade and Cooperates with gp41-Specific IgG to Increase Cell Lysis.

Immunization with HIV-1 gp41 Subunit Virosomes Induces Mucosal Antibodies Protecting Nonhuman Primates against Vaginal SHIV Challenges

In adrenocortical tissue, annexins II and VI are attached to clathrin coated vesicles in a calcium-independent manner1In memoriam: This last work as well as my scientific accomplishment are dedicated to the memory of Jeffries Wyman who was my best te

Induction of HIV-blocking anti-CCR5 IgA in Peyers's patches without histopathological alterations.

Intracellular Neutralization of HIV Transcytosis across Tight Epithelial Barriers by Anti-HIV Envelope Protein dIgA or IgM

Isotype modulates epitope specificity, affinity, and antiviral activities of anti-HIV-1 human broadly neutralizing 2F5 antibody

Ligand-blotting visualization of the LDL receptor in plasma membranes and in two classes of coated vesicles from adrenocortical cells

Live Imaging of HIV-1 Transfer across T Cell Virological Synapse to Epithelial Cells that Promotes Stromal Macrophage Infection.

Meeting of the apical and basolateral endocytic pathways of the Madin-Darby canine kidney cell in late endosomes.

Membrane translocation of diphtheria toxin fragment A exploits early to late endosome trafficking machinery

Microtubule- and motor-dependent fusion in vitro between apical and basolateral endocytic vesicles from MDCK cells

Modifications of the human oocyte plasma membrane protein pattern during preovulatory maturation

Mouse offspring after microinjection of heated spermatozoa

Mucosal IgA in exposed, uninfected subjects: evidence for a role in protection against HIV infection

Mucosal gatekeepers: Selecting HIV viruses for early infection

Natural mucosal antibodies reactive with first extracellular loop of CCR5 inhibit HIV-1 transport across human epithelial cells

OA011-01. Early events of human immunodeficiency virus type 1 (HIV-1) ex vivo penetration in the foreskin mimicking HIV-1 sexual transmission

P11-20. HIV-1 gp41-specific mucosal IgAs from highly exposed but IgG seronegative women block HIV-1 epithelial transcytosis and neutralize CD4+ cell infection

P12-16. Biochemical and immunological characterization of the plant-derived candidate HIV-1 mucosal vaccine CTB-MPR.

P19-02. High protection of female macaques from repeated intravaginal challenges with SHIV-162P3 upon mucosal vaccination with Gp41 subunits-virosomes

Partial purification of the maturation-promoting factor MPF from unfertilized eggs of Xenopus laevis

Peptide P5 (residues 628-683), comprising the entire membrane proximal region of HIV-1 gp41 and its calcium-binding site, is a potent inhibitor of HIV-1 infection

Physical interaction of the HIV-1 Nef protein with beta-COP, a component of non-clathrin-coated vesicles essential for membrane traffic.

Platelets from HIV-infected individuals on antiretroviral drug therapy with poor CD4+ T cell recovery can harbor replication-competent HIV despite viral suppression

Possible role of both the alpha and beta gamma subunits of the heterotrimeric G protein, Gs, in transcytosis of the polymeric immunoglobulin receptor.

Protecting the initial site of viral entry: an alternative HIV vaccine target ⬇️

Randomized Phase I: Safety, Immunogenicity and Mucosal Antiviral Activity in Young Healthy Women Vaccinated with HIV-1 Gp41 P1 Peptide on Virosomes

Role of heterotrimeric G proteins in membrane traffic ⬇️

Secretory IgA specific for a conserved epitope on gp41 envelope glycoprotein inhibits epithelial transcytosis of HIV-1.

Short Communication: Decreased Plasma Calcitonin Gene-Related Peptide as a Novel Biomarker for HIV-1 Disease Progression

Sorting of plasma membrane proteins in epithelial cells ⬇️

Specific lipid protein interactions characterize 3 populations of clathrin coated vesicles involved in the LDL receptor traffic

Stimulation of transcytosis of the polymeric immunoglobulin receptor by dimeric IgA.

The CH1α domain of mucosal gp41 IgA contributes to antibody specificity and antiviral functions in HIV-1 highly exposed Sero-Negative individuals

The HIV-1 viral synapse signals human foreskin keratinocytes to secrete thymic stromal lymphopoietin facilitating HIV-1 foreskin entry

The Human Penis Is a Genuine Immunological Effector Site

The adult penile urethra is a novel entry site for HIV-1 that preferentially targets resident urethral macrophages.

The binding of HIV-1 gp41 membrane proximal domain to its mucosal receptor, galactosyl ceramide, is structure-dependent

The broadly neutralizing HIV-1 IgG 2F5 elicits gp41-specific antibody-dependent cell cytotoxicity in a FcγRI-dependent manner.

The immunoglobulin CH1 constant region modulates antigen binding affinity and functional activities of the broadly neutralizing 2F5 HIV specific antibody

Transcytosis-blocking abs elicited by an oligomeric immunogen based on the membrane proximal region of HIV-1 gp41 target non-neutralizing epitopes.

Transfer of oocyte membrane fragments to fertilizing spermatozoa

Unusual feeding behavior in wild great apes, a window to understand origins of self-medication in humans: Role of sociality and physiology on learning process ⬇️

Virus like particle based strategy to elicit HIV-protective antibodies to the alpha-helic regions of gp41.

Within 1 h, HIV-1 uses viral synapses to enter efficiently the inner, but not outer, foreskin mucosa and engages Langerhans–T cell conjugates