Lista de obras - Pascal Verdier-Pinard - Dominio Público Uruguay

4,5-Diaryl-1H-pyrrole-2-carboxylates as combretastatin A-4/lamellarin T hybrids: synthesis and evaluation as anti-mitotic and cytotoxic agents

artículo científico publicado en 2006

A novel palladium-mediated coupling approach to 2,3-disubstituted benzo(b)thiophenes and its application to the synthesis of tubulin binding agents

scientific article published on 01 March 2001

A steroid derivative with paclitaxel-like effects on tubulin polymerization

artículo científico publicado en 2000

Analysis of tubulin isotypes and mutations from taxol-resistant cells by combined isoelectrofocusing and mass spectrometry

artículo científico publicado en 2003

Aneuploidy acts both oncogenically and as a tumor suppressor

artículo científico publicado en 2006

Antiangiogenic vinflunine affects EB1 localization and microtubule targeting to adhesion sites.

artículo científico publicado en 2008

Antifungal and cancer cell growth inhibitory activities of 1-(3',4',5'-trimethoxyphenyl)-2-nitro-ethylene.

artículo científico publicado en 2002

Antineoplastic agents 442. Synthesis and biological activities of dioxostatin.

artículo científico publicado en 2000

Antineoplastic agents. 379. Synthesis of phenstatin phosphate

artículo científico publicado en 1998

Antitumor agents--CLXXV. Anti-tubulin action of (+)-thiocolchicine prepared by partial synthesis

scientific article published on 01 December 1997

Antitumor agents. 172. Synthesis and biological evaluation of novel deacetamidothiocolchicin-7-ols and ester analogs as antitubulin agents

scientific article published on 01 March 1997

Biosynthesis of radiolabeled curacin A and its rapid and apparently irreversible binding to the colchicine site of tubulin

artículo científico publicado en 1999

Characterization of a human βV‐tubulin antibody and expression of this isotype in normal and malignant human tissue ⬇️

artículo científico publicado el 2 de julio de 2012

Combretastatin A4 phosphate

artículo científico publicado en 2001

Comparison of the activities of the truncated halichondrin B analog NSC 707389 (E7389) with those of the parent compound and a proposed binding site on tubulin.

artículo científico publicado en 2006

Curacin D, an antimitotic agent from the marine cyanobacterium Lyngbya majuscula

scientific article published on 01 December 1998

Designed Epothilones: Combinatorial Synthesis, Tubulin Assembly Properties, abd Cytotoxic Action against Taxol-Resistant Tumor Cells

Detection of human betaV-tubulin expression in epithelial cancer cell lines by tubulin proteomics

artículo científico publicado en 2005

Differential in vitro action of S-12363, a new vinblastine derivative, and of its epimer on microtubule proteins

artículo científico publicado en 1991

Differential in vitro association of vinca alkaloid-induced tubulin spiral filaments into aggregated spirals

artículo científico publicado en 1999

Direct Analysis of Tubulin Expression in Cancer Cell Lines by Electrospray Ionization Mass Spectrometry ⬇️

artículo científico publicado el 21 de octubre de 2003

Dolastatin 11, a marine depsipeptide, arrests cells at cytokinesis and induces hyperpolymerization of purified actin.

artículo científico publicado en 2001

EB1-binding-myomegalin protein complex promotes centrosomal microtubules functions.

artículo científico publicado en 2017

Elevated levels of microtubule destabilizing factors in a Taxol-resistant/dependent A549 cell line with an alpha-tubulin mutation.

artículo científico publicado en 2003

ErbB2-dependent chemotaxis requires microtubule capture and stabilization coordinated by distinct signaling pathways

artículo científico publicado en 2013

Eribulin targets a ch-TOG-dependent directed migration of cancer cells

artículo científico publicado en 2015

Hypoestoxide, a natural nonmutagenic diterpenoid with antiangiogenic and antitumor activity: possible mechanisms of action.

artículo científico publicado en 2002

Increased levels of a unique post-translationally modified betaIVb-tubulin isotype in liver cancer

artículo científico publicado en 2008

Insights into the mechanism of microtubule stabilization by Taxol.

artículo científico publicado en 2006

MALDI in-source decay of high mass protein isoforms: application to alpha- and beta-tubulin variants.

artículo científico publicado en 2010

Mechanisms of Taxol resistance related to microtubules. ⬇️

artículo científico publicado en 2003

Microtubule targeting agents: from biophysics to proteomics.

artículo científico publicado en 2010

Post-translational modifications to Toxoplasma gondii alpha- and beta-tubulins include novel C-terminal methylation

artículo científico publicado en 2010

Septin 9 isoform expression, localization and epigenetic changes during human and mouse breast cancer progression.

artículo científico publicado en 2011

Septin 9_i2 is downregulated in tumors, impairs cancer cell migration and alters subnuclear actin filaments.

scientific article published on 24 March 2017

Septin roles in tumorigenesis.

artículo científico publicado en 2011

Structure and absolute stereochemistry of hectochlorin, a potent stimulator of actin assembly

artículo científico publicado en 2002

Structure-activity analysis of the interaction of curacin A, the potent colchicine site antimitotic agent, with tubulin and effects of analogs on the growth of MCF-7 breast cancer cells

artículo científico publicado en 1998

Sustained intracellular retention of dolastatin 10 causes its potent antimitotic activity.

artículo científico publicado en 2000

Total synthesis of (±)-rhazinal, an alkaloidal spindle toxin from Kopsia teoi

scientific article published on 01 January 2003

Tubulin proteomics: towards breaking the code.

artículo científico publicado en 2008

Tyrosine-dependent capture of CAP-Gly domain-containing proteins in complex mixture by EB1 C-terminal peptidic probes

artículo científico publicado en 2012

Lista de obras de Pascal Verdier-Pinard

4,5-Diaryl-1H-pyrrole-2-carboxylates as combretastatin A-4/lamellarin T hybrids: synthesis and evaluation as anti-mitotic and cytotoxic agents

A novel palladium-mediated coupling approach to 2,3-disubstituted benzo(b)thiophenes and its application to the synthesis of tubulin binding agents

A steroid derivative with paclitaxel-like effects on tubulin polymerization

Analysis of tubulin isotypes and mutations from taxol-resistant cells by combined isoelectrofocusing and mass spectrometry

Aneuploidy acts both oncogenically and as a tumor suppressor

Antiangiogenic vinflunine affects EB1 localization and microtubule targeting to adhesion sites.

Antifungal and cancer cell growth inhibitory activities of 1-(3',4',5'-trimethoxyphenyl)-2-nitro-ethylene.

Antineoplastic agents 442. Synthesis and biological activities of dioxostatin.

Antineoplastic agents. 379. Synthesis of phenstatin phosphate

Antitumor agents--CLXXV. Anti-tubulin action of (+)-thiocolchicine prepared by partial synthesis

Antitumor agents. 172. Synthesis and biological evaluation of novel deacetamidothiocolchicin-7-ols and ester analogs as antitubulin agents

Biosynthesis of radiolabeled curacin A and its rapid and apparently irreversible binding to the colchicine site of tubulin

Characterization of a human βV‐tubulin antibody and expression of this isotype in normal and malignant human tissue ⬇️

Combretastatin A4 phosphate

Comparison of the activities of the truncated halichondrin B analog NSC 707389 (E7389) with those of the parent compound and a proposed binding site on tubulin.

Curacin D, an antimitotic agent from the marine cyanobacterium Lyngbya majuscula

Designed Epothilones: Combinatorial Synthesis, Tubulin Assembly Properties, abd Cytotoxic Action against Taxol-Resistant Tumor Cells

Detection of human betaV-tubulin expression in epithelial cancer cell lines by tubulin proteomics

Differential in vitro action of S-12363, a new vinblastine derivative, and of its epimer on microtubule proteins

Differential in vitro association of vinca alkaloid-induced tubulin spiral filaments into aggregated spirals

Direct Analysis of Tubulin Expression in Cancer Cell Lines by Electrospray Ionization Mass Spectrometry ⬇️

Dolastatin 11, a marine depsipeptide, arrests cells at cytokinesis and induces hyperpolymerization of purified actin.

EB1-binding-myomegalin protein complex promotes centrosomal microtubules functions.

Elevated levels of microtubule destabilizing factors in a Taxol-resistant/dependent A549 cell line with an alpha-tubulin mutation.

ErbB2-dependent chemotaxis requires microtubule capture and stabilization coordinated by distinct signaling pathways

Eribulin targets a ch-TOG-dependent directed migration of cancer cells

Hypoestoxide, a natural nonmutagenic diterpenoid with antiangiogenic and antitumor activity: possible mechanisms of action.

Increased levels of a unique post-translationally modified betaIVb-tubulin isotype in liver cancer

Insights into the mechanism of microtubule stabilization by Taxol.

MALDI in-source decay of high mass protein isoforms: application to alpha- and beta-tubulin variants.

Mechanisms of Taxol resistance related to microtubules. ⬇️

Microtubule targeting agents: from biophysics to proteomics.

Post-translational modifications to Toxoplasma gondii alpha- and beta-tubulins include novel C-terminal methylation

Septin 9 isoform expression, localization and epigenetic changes during human and mouse breast cancer progression.

Septin 9_i2 is downregulated in tumors, impairs cancer cell migration and alters subnuclear actin filaments.

Septin roles in tumorigenesis.

Structure and absolute stereochemistry of hectochlorin, a potent stimulator of actin assembly

Structure-activity analysis of the interaction of curacin A, the potent colchicine site antimitotic agent, with tubulin and effects of analogs on the growth of MCF-7 breast cancer cells

Sustained intracellular retention of dolastatin 10 causes its potent antimitotic activity.

Total synthesis of (±)-rhazinal, an alkaloidal spindle toxin from Kopsia teoi

Tubulin proteomics: towards breaking the code.

Tyrosine-dependent capture of CAP-Gly domain-containing proteins in complex mixture by EB1 C-terminal peptidic probes