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Lista de obras de David G Le Couteur

90th Anniversary Commentary: Caloric Restriction Effects on Aging

A Blueprint for Developing Therapeutic Approaches That Increase Healthspan and Delay Death

artículo científico publicado en 2010

A Comparison of Two Mouse Frailty Assessment Tools

artículo científico publicado en 2017

A Liver Capsular Network of Monocyte-Derived Macrophages Restricts Hepatic Dissemination of Intraperitoneal Bacteria by Neutrophil Recruitment

artículo científico publicado en 2017

A Sieve-Raft Hypothesis for the regulation of endothelial fenestrations

artículo científico

A Vascular Theory of Aging

artículo científico publicado en 2010

A cross-sectional study of perceived dental treatment needs and oral health status in community-dwelling older Australian men: The Concord Health and Ageing in Men Project

artículo científico publicado en 2020

A high-fat diet and NAD(+) activate Sirt1 to rescue premature aging in cockayne syndrome

artículo científico publicado en 2014

A longitudinal study of knee pain in older men: Concord Health and Ageing in Men Project.

artículo científico publicado en 2013

A multicenter, case-control study of the effects of antihypertensive therapy on orthostatic hypotension, postprandial hypotension, and falls in octo- and nonagenarians in residential care facilities

artículo científico publicado en 2003

A pilot randomized clinical trial utilizing the drug burden index to reduce exposure to anticholinergic and sedative medications in older people

artículo científico publicado en 2010

A randomized clinical trial of activated charcoal for the routine management of oral drug overdose

artículo científico publicado en 2005

A standardized method for the analysis of liver sinusoidal endothelial cells and their fenestrations by scanning electron microscopy

artículo científico publicado en 2015

Acetaminophen hepatotoxicity in mice: Effect of age, frailty and exposure type

artículo científico publicado en 2015

Active Vitamin D (1,25 Dihydroxyvitamin D) Is Associated With Chronic Pain in Older Australian Men: The Concord Health and Ageing in Men Project

article

Adaptive Senectitude: The Prolongevity Effects of Aging ⬇️

artículo científico publicado el 11 de octubre de 2010

Adequacy of nutritional intake among older men living in Sydney, Australia: findings from the Concord Health and Ageing in Men Project (CHAMP)

article

Adherence, persistence and continuation with cholinesterase inhibitors in Alzheimer's disease

artículo científico publicado en 2011

Adverse Geriatric Outcomes Secondary to Polypharmacy in a Mouse Model: The Influence of Aging

artículo científico publicado en 2015

Age-environment and gene-environment interactions in the pathogenesis of Parkinson's disease

artículo científico publicado en 2002

Age-related alteration in hepatic disposition of the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and pesticides

artículo científico publicado en 2002

Age-related changes in scavenger receptor-mediated endocytosis in rat liver sinusoidal endothelial cells

artículo científico publicado en 2010

Age-related changes in the hepatic sinusoidal endothelium impede lipoprotein transfer in the rat

artículo científico publicado en 2005

Age-related changes in the liver sinusoidal endothelium: a mechanism for dyslipidemia

artículo científico publicado en 2007

Age-related loss of responsiveness to 2,5-dimethoxy-4-iodoamphetamine in liver sinusoidal endothelial cells

artículo científico publicado en 2013

Age-related pseudocapillarization of the human liver

artículo científico publicado en 2003

Age-related pseudocapillarization of the liver sinusoidal endothelium impairs the hepatic clearance of acetaminophen in rats

artículo científico publicado en 2011

Ageing and Reoxygenation Injury in the Liver

artículo científico publicado en 1999

Aging and the response of the isolated perfused rat liver to vasoactive drugs.

artículo científico publicado en 1992

Aging biology and geriatric clinical pharmacology

artículo científico publicado en 2004

Aging biology and novel targets for drug discovery

artículo científico publicado en 2011

Aging, Drugs, and Drug Metabolism

artículo científico publicado en 2011

Aging, lifestyle and dementia

artículo científico publicado en 2019

Alcohol consumption and tobacco smoking among community-dwelling older Australian men: the Concord Health and Ageing in Men Project

artículo científico publicado en 2013

Alterations in liver sinusoidal endothelium in a baboon model of type 1 diabetes

article

An Australian community jury to consider case-finding for dementia: Differences between informed community preferences and general practice guidelines.

artículo científico publicado en 2019

Anti-aging therapies, cognitive impairment and dementia

artículo científico publicado en 2019

Anticholinergic medicines use among older adults before and after initiating dementia medicines

artículo científico publicado en 2019

Antimycin A-induced defenestration in rat hepatic sinusoidal endothelial cells.

artículo científico publicado en 2003

Apolipoprotein E and Health in Older Men: The Concord Health and Ageing in Men Project

artículo científico publicado en 2020

Are glycans the Holy Grail for biomarkers of aging?

artículo científico publicado en 2013

Are sirtuins viable targets for improving healthspan and lifespan?

artículo científico publicado en 2012

Assessing the harms of polypharmacy requires careful interpretation and consistent definitions

artículo científico publicado en 2014

Association Rules Analysis of Comorbidity and Multimorbidity: The Concord Health and Aging in Men Project

artículo científico publicado en 2015

Association between pain and the frailty phenotype in older men: longitudinal results from the Concord Health and Ageing in Men Project (CHAMP).

artículo científico publicado en 2018

Association rules method and big data: Evaluating frequent medication combinations associated with fractures in older adults.

artículo científico publicado en 2018

Associations between circulating reproductive hormones and SHBG and prevalent and incident metabolic syndrome in community-dwelling older men: the Concord Health and Ageing in Men Project.

artículo científico publicado en 2014

Associations between frailty and serum 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D concentrations in older Australian men: the Concord Health and Ageing in Men Project.

artículo científico publicado en 2013

Associations between nutrient intakes and dietary patterns with different sarcopenia definitions in older Australian men: the concord health and ageing in men project

scientific article published on 07 October 2020

Associations between nutrient intakes and dietary patterns with different sarcopenia definitions in older Australian men: the concord health and ageing in men project - ERRATUM

scientific article published on 27 November 2020

Associations between oral health and depressive symptoms: Findings from the Concord Health and Ageing in Men Project

scientific article published on 13 January 2020

Associations between serum 25-hydroxyvitamin D concentrations and multiple health conditions, physical performance measures, disability, and all-cause mortality: the Concord Health and Ageing in Men Project.

artículo científico publicado en 2014

Associations between sun sensitive pigmentary genes and serum prostate specific antigen levels

artículo científico publicado en 2018

Associations of Body Composition Trajectories with Bone Mineral Density, Muscle Function, Falls, and Fractures in Older Men: The Concord Health and Ageing in Men Project

artículo científico publicado en 2019

Associations of sarcopenic obesity with the metabolic syndrome and insulin resistance over five years in older men: The Concord Health and Ageing in Men Project

artículo científico publicado en 2018

Atypical antipsychotic medications and risk of falls in residents of aged care facilities

artículo científico publicado en 2005

Author reply

scientific article published on 01 August 2015

Back pain in older male Italian-born immigrants in Australia: The importance of socioeconomic factors

article

Basal activity of Kupffer cells increases with old age.

artículo científico publicado en 2007

Beneficial effects of the synthetic antioxidant tert-butyl bisphenol on the hepatic microcirculation in a rat model of diabetes mellitus

artículo científico publicado en 2011

Benzodiazepines and risk of hip fractures in older people: a review of the evidence

artículo científico publicado en 2003

Beta-blockers and heart failure in older people

artículo científico publicado en 2006

Branched chain amino acids impact health and lifespan indirectly via amino acid balance and appetite control

scientific article published on 29 April 2019

Branched chain amino acids, aging and age-related health

artículo científico publicado en 2020

Branched chain amino acids, cardiometabolic risk factors and outcomes in older men: the Concord Health and Ageing in Men Project

scientific article published on 20 August 2019

CARDIO-METABOLIC CONSEQUENCES OF DIETARY CARBOHYDRATES: RECONCILING CONTRADICTIONS USING NUTRITIONAL GEOMETRY

artículo científico publicado en 2020

CD8+ T cell tolerance following antigen recognition on hepatocytes

scientific article published on 09 September 2009

COVID-19 is a disease of older people

artículo científico publicado en 2020

Caloric Restriction Research: New Perspectives on the Biology of Aging

artículo científico publicado en 2017

Caloric restriction reduces age-related pseudocapillarization of the hepatic sinusoid

artículo científico publicado en 2007

Caloric restriction versus drug therapy to delay the onset of aging diseases and extend life

artículo científico publicado en 2005

Carbon Monoxide Disposition and Permeability-Surface Area Product in the Foetal Circulation of the Perfused Term Human Placenta

artículo científico publicado en 2003

Caregiving and all-cause mortality in older men 2005-15: the Concord Health and Ageing in Men Project

article

Caution before embracing serum markers of liver fibrosis in clinical practice

artículo científico publicado en 2005

Cell Membrane Transport of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the Liver and Systemic Bioavailability ⬇️

artículo científico publicado el 23 de noviembre de 2001

Central nervous system SIRT1 expression is required for cued and contextual fear conditioning memory responses in aging mice

artículo científico publicado en 2019

Changes in micronutrient intake and factors associated with this change among older Australian men: the Concord Health and Ageing in Men Project

artículo científico publicado en 2020

Changes in reproductive hormone concentrations predict the prevalence and progression of the frailty syndrome in older men: the concord health and ageing in men project.

artículo científico publicado en 2011

Chronic and criminal administration of Nerium oleander

artículo científico publicado en 2002

Chronic polypharmacy with increasing Drug Burden Index (DBI) exacerbates frailty and impairs physical function, with effects attenuated by deprescribing, in aged mice

artículo científico publicado en 2020

Clinical implications of changes in hepatic drug metabolism in older people

artículo científico publicado en 2005

Clinical pharmacology

artículo científico publicado en 2002

Clinical pharmacology in the geriatric patient

artículo científico publicado en 2007

Clinical pharmacology of analgesic medicines in older people: impact of frailty and cognitive impairment

artículo científico publicado en 2011

Cognitive and behavioral evaluation of nutritional interventions in rodent models of brain aging and dementia.

artículo científico publicado en 2017

Cohort Profile: The Concord Health and Ageing in Men Project (CHAMP)

article

Community-dwelling older men with dementia are at high risk of hip fracture, but not any other fracture: The Concord Health and Aging in Men Project

article

Comorbidity and vascular cognitive impairment-no dementia (VCI-ND).

artículo científico publicado en 2017

Comparing the Effects of Low-Protein and High-Carbohydrate Diets and Caloric Restriction on Brain Aging in Mice

artículo científico publicado en 2018

Comparison of clinical risk factors for incident fracture in obese and non-obese community-dwelling older men

scientific article published on 15 May 2020

Conclusion: Human Calorie Restriction and Anti-aging Therapy

artículo científico publicado en 2010

Contribution of psychosocial factors to socioeconomic inequalities in mortality among older Australian men: a population-based cohort study

scientific article published on 07 October 2020

Correction: Cystathionine-Gamma-Lyase Gene Deletion Protects Mice against Inflammation and Liver Sieve Injury following Polymicrobial Sepsis

artículo científico publicado en 2017

Corrigendum to: The Effect of Aging on Acetaminophen Pharmacokinetics, Toxicity and Nrf2 in Fischer 344 Rats

artículo científico publicado en 2019

Cross-Sectional and Longitudinal Associations Between Anemia and Frailty in Older Australian Men: The Concord Health and Aging in Men Project

artículo científico publicado en 2015

Cross-Sectional and Longitudinal Relationships Between Inflammatory Biomarkers and Frailty in Community-dwelling Older Men: The Concord Health and Ageing in Men Project

artículo científico publicado en 2017

Cross-sectional and longitudinal associations between the active vitamin D metabolite (1,25 dihydroxyvitamin D) and haemoglobin levels in older Australian men: the Concord Health and Ageing in Men Project

artículo científico publicado en 2015

Cystathionine-Gamma-Lyase Gene Deletion Protects Mice against Inflammation and Liver Sieve Injury following Polymicrobial Sepsis

artículo científico publicado en 2016

Cystathionine-Gamma-Lyase-Derived Hydrogen Sulfide-Regulated Substance P Modulates Liver Sieve Fenestrations in Caecal Ligation and Puncture-Induced Sepsis

scientific article published on 29 June 2019

DNA damage, NF-κB and accelerated aging ⬇️

artículo científico publicado el 27 de agosto de 2012

Defining the Nutritional and Metabolic Context of FGF21 Using the Geometric Framework.

artículo científico publicado en 2016

Delivering the right information to the right person at the right time to facilitate deprescribing in hospital: a mixed methods multisite study to inform decision support design in Australia

artículo científico publicado en 2019

Deprescribing Benzodiazepines in Older Patients: Impact of Interventions Targeting Physicians, Pharmacists, and Patients

scientific article published on 01 June 2018

Deprescribing trials: methods to reduce polypharmacy and the impact on prescribing and clinical outcomes

artículo científico

Determinants of serum-induced SIRT1 expression in older men: the CHAMP study

artículo científico publicado en 2010

Development of a mentorship programme for rural general practitioners by visiting specialist physicians

artículo científico publicado en 2005

Development of consumer information leaflets for deprescribing in older hospital inpatients: a mixed-methods study

scientific article published on 11 December 2019

Diet mediates the relationship between longevity and reproduction in mammals ⬇️

artículo científico publicado el 12 de enero de 2012

Diet quality and its implications on the cardio-metabolic, physical and general health of older men: the Concord Health and Ageing in Men Project (CHAMP).

artículo científico publicado en 2017

Diet-Microbiome Interactions in Health Are Controlled by Intestinal Nitrogen Source Constraints.

artículo científico publicado en 2016

Dietary Protein to Carbohydrate Ratio and Caloric Restriction: Comparing Metabolic Outcomes in Mice

artículo científico publicado en 2015

Dietary approaches that delay age-related diseases

artículo científico publicado en 2006

Dietary macronutrient content, age-specific mortality and lifespan

scientific article published on 01 May 2019

Dietary macronutrients and the aging liver sinusoidal endothelial cell.

artículo científico publicado en 2016

Dietary protein, aging and nutritional geometry

artículo científico publicado en 2017

Differential Effects of Kupffer Cell Inactivation on Inflammation and The Liver Sieve Following Caecal-Ligation and Puncture-Induced Sepsis in Mice

artículo científico publicado en 2016

Discontinuation of Statins in Routine Care Settings

artículo científico publicado en 2013

Discontinuing drug treatments

artículo científico publicado en 2014

Do medical courses adequately prepare interns for safe and effective prescribing in New South Wales public hospitals?

artículo científico publicado en 2009

Does Combined Osteopenia/Osteoporosis and Sarcopenia Confer Greater Risk of Falls and Fracture Than Either Condition Alone in Older Men? The Concord Health and Ageing in Men Project

artículo científico publicado en 2019

Dosing Errors: Age-Related Changes in Pharmacokinetics

Drug Burden Index and change in cognition over time in community-dwelling older men: the CHAMP study.

artículo científico publicado en 2016

Drug Burden Index and physical function in older Australian men.

artículo científico publicado en 2009

Drug burden index and beers criteria: impact on functional outcomes in older people living in self-care retirement villages

artículo científico publicado en 2012

Effects of Changes in Number of Medications and Drug Burden Index Exposure on Transitions Between Frailty States and Death: The Concord Health and Ageing in Men Project Cohort Study.

artículo científico publicado en 2016

Effects of Drug Burden Index on Cognitive Function in Older Men

artículo científico publicado en 2012

Effects of Old Age on Hepatocyte Oxygenation

article

Effects of dietary protein to carbohydrate balance on energy intake, fat storage, and heat production in mice

article

Effects of hydrogen peroxide and apolipoprotein E isoforms on apolipoprotein E trafficking in HepG2 cells.

artículo científico publicado en 2009

Effects of old age on vascular complexity and dispersion of the hepatic sinusoidal network

artículo científico publicado en 2008

Epidemiology of falls in elderly semi-independent residents in residential care

Erratum to: COVID-19 Through the Lens of Gerontology

scientific article published on 17 April 2020

Estimation of lean body weight in older community-dwelling men

artículo científico publicado en 2010

Ethnicity and falls in older men: low rate of falls in Italian-born men in Australia

article

Evaluating Calculated Free Testosterone as a Predictor of Morbidity and Mortality Independent of Testosterone for Cross-sectional and 5 year Longitudinal Health Outcomes in Older Men: The Concord Health and Ageing in Men Project.

artículo científico publicado en 2017

Experimental gerontological research in Australia

artículo científico publicado en 2002

Fall-related mortality trends in Australia and the United Kingdom: Implications for research and practice

artículo científico publicado en 2020

Fenestrations and lipoproteins

artículo científico publicado en 2010

Fenestrations in the Liver Sinusoidal Endothelial Cell

Food Intake, Life Style, Aging and Human Longevity

Food Restriction, Hormones, Genes and Aging

article

Frailty and oral health: Findings from the Concord Health and Ageing in Men Project

scientific article published on 06 October 2019

Frailty and use of health and community services by community-dwelling older men: the Concord Health and Ageing in Men Project

article

Frailty, a multisystem ageing syndrome

artículo científico publicado en 2020

Future directions of resveratrol research.

artículo científico publicado en 2018

Going Beyond the Guidelines in Individualising the Use of Antihypertensive Drugs in Older Patients

scientific article published on 01 August 2019

Hallmarks of Aging in the Liver

scientific article published on 07 August 2019

Health benefits of late-onset metformin treatment every other week in mice

artículo científico publicado en 2017

Health status, health behaviours and anxiety symptoms of older male caregivers: Findings from the Concord Health and Ageing in Men Project.

artículo científico publicado en 2017

Hepatic oxygen supplementation as therapy in cirrhotic liver disease

artículo científico publicado en 1999

Hepatic phospholipid changes induced by sustained oxygen supplementation

artículo científico publicado en 2002

Hepatic pseudocapillarisation and atherosclerosis in ageing

artículo científico publicado en 2002

Hepatic pseudocapillarization in aged mice

artículo científico publicado en 2005

Hepatic sinusoidal cells in health and disease: update from the 14th International Symposium.

artículo científico publicado en 2009

Hepatic sinusoidal pseudocapillarization with aging in the non-human primate

artículo científico publicado en 2003

Hepatocyte entry leads to degradation of autoreactive CD8 T cells

artículo científico publicado en 2011

High risk prescribing in older adults: prevalence, clinical and economic implications and potential for intervention at the population level

artículo científico publicado en 2013

High-risk prescribing and incidence of frailty among older community-dwelling men.

artículo científico publicado en 2012

High-risk prescribing in older people: more harm than good?

Higher Impact Physical Activity is Associated with Maintenance of Bone Mineral Density but Not Reduced Incident Falls or Fractures in Older Men: The Concord Health and Ageing in Men Project

artículo científico publicado en 2020

How fast does the Grim Reaper walk? Receiver operating characteristics curve analysis in healthy men aged 70 and over

artículo científico publicado en 2011

Hydroxychloroquine overdose: toxicokinetics and management.

artículo científico publicado en 1999

Hyperlipidemia and surfactants: the liver sieve is a link

artículo científico publicado en 2006

IUPHAR International geriatric clinical pharmacology curriculum for medical students

artículo científico publicado en 2019

Idalopirdine: another disappointment for people with dementia

artículo científico publicado en 2018

Improving medicine selection for older people - do we need an Australian classification for inappropriate medicines use?

artículo científico publicado el 1 de enero de 2012

Intravital multiphoton imaging of the selective uptake of water-dispersible quantum dots into sinusoidal liver cells

artículo científico publicado en 2014

Intrusive pain and worry about health in older men: the CHAMP study.

artículo científico publicado en 2010

Ischemia/Reperfusion Injury in the Aged Liver: The Importance of the Sinusoidal Endothelium in Developing Therapeutic Strategies for the Elderly

artículo científico publicado en 2020

Ischemic heart disease, prescription of optimal medical therapy and geriatric syndromes in community-dwelling older men: A population-based study.

artículo científico publicado en 2015

It's the holes that matter

artículo científico publicado en 2017

Journal of Gerontology: Biological Sciences. A Long Tradition in Advancing Aging Biology and Translational Gerontology

artículo científico publicado en 2018

Life extension by calorie restriction in humans

artículo científico publicado en 2007

Lifestyle factors, medications, and disease influence bone mineral density in older men: findings from the CHAMP study.

artículo científico publicado en 2010

Liver aging and pseudocapillarization in a Werner syndrome mouse model.

artículo científico publicado en 2013

Liver dysfunction and heart failure

scientific article published on 01 June 2003

Liver sinusoidal endothelial cells and acute non-oxidative hepatic injury induced by Pseudomonas aeruginosa pyocyanin

artículo científico publicado en 2008

Liver sinusoidal endothelial fenestrations in caveolin-1 knockout mice

artículo científico publicado en 2010

Long-term Dietary Macronutrients and Hepatic Gene Expression in Aging Mice.

artículo científico publicado en 2018

Longitudinal Associations Between Vitamin D Metabolites and Sarcopenia in Older Australian men: The Concord Health and Aging in Men Project

artículo científico publicado en 2017

Longitudinal Relationships between Reproductive Hormones and Cognitive Decline in Older Men: The Concord Health and Ageing in Men Project.

artículo científico publicado en 2015

Longitudinal Relationships of Circulating Reproductive Hormone With Functional Disability, Muscle Mass, and Strength in Community-Dwelling Older Men: The Concord Health and Ageing in Men Project

article

Longitudinal and cross-sectional relationships of circulating reproductive hormone levels to self-rated health and health-related quality of life in community-dwelling older men.

artículo científico publicado en 2014

Longitudinal associations between body composition, sarcopenic obesity and outcomes of frailty, disability, institutionalisation and mortality in community-dwelling older men: The Concord Health and Ageing in Men Project

artículo científico publicado en 2016

Loss of Muscle Strength, Mass (Sarcopenia), and Quality (Specific Force) and Its Relationship with Functional Limitation and Physical Disability: The Concord Health and Ageing in Men Project

article

Low Hemoglobin Concentrations Are Associated With Sarcopenia, Physical Performance, and Disability in Older Australian Men in Cross-sectional and Longitudinal Analysis: The Concord Health and Ageing in Men Project.

artículo científico publicado en 2016

Low levels of 25-hydroxy vitamin D and active 1,25-dihydroxyvitamin D independently associated with type 2 diabetes mellitus in older Australian men: the Concord Health and Ageing in Men Project

artículo científico publicado en 2014

Low total cholesterol is associated with increased major adverse cardiovascular events in men aged ≥70 years not taking statins

artículo científico publicado en 2019

Lower Urinary Tract Symptoms and Incident Falls in Community Dwelling Older Men: The Concord Health and Ageing in Men Project.

artículo científico publicado en 2016

MDR1 and MRP expression in chronic B-cell lymphoproliferative disorders

artículo científico publicado en 1998

Macronutrient balance, reproductive function, and lifespan in aging mice.

artículo científico publicado en 2015

Macronutrients and caloric intake in health and longevity

artículo científico publicado en 2015

Manipulating fenestrations in young and old liver sinusoidal endothelial cells

artículo científico publicado en 2018

Marked changes of the hepatic sinusoid in a transgenic mouse model of acute immune-mediated hepatitis

artículo científico publicado en 2006

Medication withdrawal trials in people aged 65 years and older: a systematic review.

artículo científico publicado en 2008

Mild cognitive impairment predicts institutionalization among older men: a population-based cohort study

artículo científico publicado en 2012

Mitochondrial dysfunction in some oxidative stress-related genetic diseases: Ataxia-Telangiectasia, Down Syndrome, Fanconi Anaemia and Werner Syndrome

artículo científico publicado en 2010

Mixed Evidence of an Association between Self-Rated Hearing Difficulties and Falls: Prospective Analysis of Two Longitudinal Studies

scientific article published in 2022

Mortality Paradox of Older Italian-Born Men in Australia: The Concord Health and Ageing in Men Project

artículo científico publicado en 2020

Multiple cellular pathways regulate lipid droplet homeostasis for the establishment of polarity in collagen sandwich-cultured hepatocytes

scientific article published on 14 August 2019

Multiple, but not traditional risk factors predict mortality in older people: the Concord Health and Ageing in Men Project

artículo científico publicado en 2014

N-Acetyl cysteine does not prevent liver toxicity from chronic low-dose plus subacute high-dose paracetamol exposure in young or old mice

artículo científico publicado en 2016

NAD+ Repletion Rescues Female Fertility during Reproductive Aging

artículo científico publicado en 2020

Natural history of non-neurogenic overactive bladder and urinary incontinence over 5 years in community-dwelling older men: The concord health and aging in men project.

artículo científico publicado en 2016

Natural history of post-void residual urine volume over 5 years in community-dwelling older men: The Concord Health and Ageing in Men Project.

artículo científico publicado en 2017

New Horizons: Dietary protein, ageing and the Okinawan ratio

artículo científico publicado en 2016

Nonsteroidal anti-inflammatory drugs (NSAIDs) in older people: Prescribing patterns according to pain prevalence and adherence to clinical guidelines

scientific article published on 20 June 2014

Not all older men have the chronic diseases associated with severe COVID-19

scientific article published on 01 September 2020

Novel targets for delaying aging: The importance of the liver and advances in drug delivery

artículo científico publicado en 2018

Nutritional ecology and the evolution of aging.

artículo científico publicado en 2016

Nutritional strategies to optimise cognitive function in the aging brain.

artículo científico publicado en 2016

Of Older Mice and Men: Branched-Chain Amino Acids and Body Composition

scientific article published on 13 August 2019

Off-Label Use of Medicines: Time for Action

scientific article published on 20 June 2012

Old age and the hepatic sinusoid

scientific article published on June 2008

Old age is associated with ultrastructural changes in isolated rat liver sinusoidal endothelial cells

artículo científico publicado en 2009

Optimal cutoff of polypharmacy and outcomes - reply

artículo científico publicado en 2013

Oral health and cognitive status in the Concord Health and Ageing in Men Project: A cross-sectional study in community-dwelling older Australian men

scientific article published on 30 March 2020

Organizational Innovation for Developing New Medicines That Target Aging and Age-Related Conditions

artículo científico publicado en 2020

P-Glycoprotein, Multidrug-Resistance-Associated Protein and Parkinson’s Disease

artículo científico publicado en 2001

Pain, frailty and comorbidity on older men: the CHAMP study.

artículo científico publicado en 2008

Parkinson's disease, pesticides, and glutathione transferase polymorphisms

artículo científico publicado en 1998

Pathogenesis of the hyperlipidemia of Gram-negative bacterial sepsis may involve pathomorphological changes in liver sinusoidal endothelial cells

artículo científico publicado en 2010

Pesticides and Parkinson's disease.

artículo científico publicado en 1999

Pharmaco-epistemology for the prescribing geriatrician

artículo científico publicado en 2008

Physicians need to take the lead in deprescribing.

artículo científico publicado en 2015

Political drive to screen for pre-dementia: not evidence based and ignores the harms of diagnosis

artículo científico publicado en 2013

Poloxamer 407 increases the recovery of paracetamol in the isolated perfused rat liver

artículo científico publicado en 2010

Polypharmacy cutoff and outcomes: five or more medicines were used to identify community-dwelling older men at risk of different adverse outcomes

artículo científico publicado en 2012

Polypharmacy in older adults: Association Rule and Frequent-Set Analysis to evaluate concomitant medication use.

artículo científico publicado en 2016

Postprandial systolic blood pressure responses of older people in residential care: association with risk of falling

artículo científico publicado en 2003

Predicting participation restriction in community-dwelling older men: the Concord Health and Ageing in Men Project

artículo científico publicado en 2013

Predictors of the rate of BMD loss in older men: findings from the CHAMP study.

artículo científico publicado en 2012

Preliminary analysis of the sinusoidal endothelium and space of Disse in ageing Papio hamadrayas

artículo científico publicado en 2004

Prescribing in older people.

artículo científico publicado en 2004

Prevalence and treatment of osteoporosis in older Australian men: findings from the CHAMP study.

artículo científico publicado en 2010

Prevalence of the geriatric syndromes and frailty in older men living in the community: The Concord Health and Ageing in Men Project

artículo científico publicado en 2016

Progressive Temporal Change in Serum SHBG, But Not in Serum Testosterone or Estradiol, Is Associated With Bone Loss and Incident Fractures in Older Men: The Concord Health and Ageing in Men Project.

artículo científico publicado en 2016

Progressive familial intrahepatic cholestasis: genetic disorders of biliary transporters

artículo científico publicado en 2005

Proinflammatory Diet Increases Circulating Inflammatory Biomarkers and Falls Risk in Community-Dwelling Older Men

scientific article published on 01 February 2020

Prospective Associations Between Dietary Antioxidant Intake and Frailty in Older Australian Men: The Concord Health and Ageing in Men Project

scientific article published on 01 January 2020

Prostate-specific antigen levels in men aged 70 years and over: findings from the CHAMP study.

artículo científico publicado en 2012

Pseudomonas aeruginosa and the hyperlipidaemia of sepsis

artículo científico publicado en 2009

Psychotropic drug use and alcohol drinking in community-dwelling older Australian men: the CHAMP study.

artículo científico publicado en 2012

Putting the balance back in diet

artículo científico publicado en 2015

Quaternary protein modeling to predict the function of DNA variation found in human mitochondrial cytochrome c oxidase

artículo científico publicado en 2013

Rapid Intestinal Uptake and Targeted Delivery to the Liver Endothelium Using Orally Administered Silver Sulfide Quantum Dots

artículo científico publicado en 2020

Reactions of Pseudomonas aeruginosa pyocyanin with reduced glutathione.

artículo científico publicado en 2008

Red yeast rice for dyslipidemia in statin-intolerant patients

artículo científico publicado en 2010

Reducing Drugs in Older Adults Is More ⬇️

artículo científico publicado el 9 de mayo de 2011

Reducing inappropriate polypharmacy: the process of deprescribing

artículo científico publicado en 2015

Reproductive Hormones and Longitudinal Change in Bone Mineral Density and Incident Fracture Risk in Older Men: The Concord Health and Aging in Men Project.

artículo científico publicado en 2015

Residential age care and domiciliary oral health services: Reach-OHT-The development of a metropolitan oral health programme in Sydney, Australia

artículo científico publicado en 2017

Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span

artículo científico publicado en 2008

Resveratrol improves health and survival of mice on a high-calorie diet

artículo científico publicado en 2006

Resveratrol improves insulin resistance hyperglycemia and hepatosteatosis but not hypertriglyceridemia, inflammation, and life span in a mouse model for Werner syndrome

artículo científico publicado en 2010

SIRT1 Polymorphisms and Serum-Induced SIRT1 Protein Expression in Aging and Frailty: The CHAMP Study.

artículo científico publicado en 2017

Sarcopenia Is Associated With Incident Disability, Institutionalization, and Mortality in Community-Dwelling Older Men: The Concord Health and Ageing in Men Project

artículo científico publicado en 2015

Sarcopenic Obesity and Its Temporal Associations With Changes in Bone Mineral Density, Incident Falls, and Fractures in Older Men: The Concord Health and Ageing in Men Project

artículo científico publicado en 2016

Sedative load and functional outcomes in community-dwelling older Australian men: the CHAMP study

article

Serum uric acid is associated with bone health in older men: A cross-sectional population-based study

artículo científico publicado en 2011

Sex and Aging.

artículo científico publicado en 2017

Sex-specific metabolic responses to 6 hours fasting during the active phase in young mice

scientific article published on 21 March 2020

Sexual Function and Mortality in Older Men: The Concord Health and Ageing in Men Project.

artículo científico publicado en 2016

Should family physicians routinely screen patients for cognitive impairment? No: screening has been inappropriately urged despite absence of evidence

artículo científico publicado en 2014

Sleep disturbances and falls in older people.

artículo científico publicado en 2007

Socioeconomic status and bone health in community-dwelling older men: the CHAMP Study.

artículo científico publicado en 2010

Socioeconomic status, health-related behaviours, and death among older people: the Concord health and aging in men project prospective cohort study

artículo científico publicado en 2020

Solanezumab and the amyloid hypothesis for Alzheimer's disease

artículo científico publicado en 2016

Standardized, Multidisciplinary Approaches for the Study of Aging Biology and for Translation of Aging Interventions.

artículo científico publicado en 2016

Statin use and clinical outcomes in older men: a prospective population-based study

artículo científico publicado en 2013

Stem Cell Transplantation for Frailty.

artículo científico publicado en 2017

Sucrose and starch intake contribute to reduced alveolar bone height in a rodent model of naturally occurring periodontitis

artículo científico publicado en 2019

Systemic VEGF-A Neutralization Ameliorates Diet-Induced Metabolic Dysfunction

artículo científico publicado en 2014

T lymphocytes interact with hepatocytes through fenestrations in murine liver sinusoidal endothelial cells

scientific article published on 01 November 2006

Temporal Changes in Androgens and Estrogens Are Associated With All-Cause and Cause-Specific Mortality in Older Men.

artículo científico publicado en 2016

Temporal Trend in Androgen Status and Androgen-Sensitive Outcomes in Older Men

artículo científico publicado en 2016

Temporal associations between sexual function and cognitive function in community-dwelling older men: the Concord Health and Ageing in Men Project

scientific article published on 01 November 2018

Texture-modified food and fluids in dementia and residential aged care facilities

artículo científico

The ACE deletion polymorphism is not associated with Parkinson's disease.

artículo científico publicado en 1999

The Aging Liver and the Effects of Long Term Caloric Restriction

The C-caffeine breath test distinguishes significant fibrosis in chronic hepatitis B and reflects response to lamivudine therapy

artículo científico publicado en 2005

The Cys282Tyr polymorphism in the HFE gene in Australian Parkinson's disease patients

article

The Effect of Acute Oxidative Stress on the Ultrastructure of the Perfused Rat Liver

artículo científico publicado en 2001

The Effects of Dietary Macronutrient Balance on Skin Structure in Aging Male and Female Mice.

artículo científico publicado en 2016

The Effects of Metformin on Age-Related Changes in the Liver Sinusoidal Endothelial Cell

scientific article published on 01 January 2020

The Ethics of Prescribing Medications to Older People

The Evolution of Research on Ageing and Nutrition

scientific article published on 10 September 2013

The Geometric Framework for Nutrition as a tool in precision medicine.

artículo científico publicado en 2017

The Impact of Poloxamer 407 on the Ultrastructure of the Liver and Evidence for Clearance by Extensive Endothelial and Kupffer Cell Endocytosis

article

The Influence of Macronutrients on Splanchnic and Hepatic Lymphocytes in Aging Mice

artículo científico publicado en 2014

The Longitudinal Relationship of Sexual Function and Androgen Status in Older Men: The Concord Health and Ageing in Men Project

article

The Ratio of Macronutrients, Not Caloric Intake, Dictates Cardiometabolic Health, Aging, and Longevity in Ad Libitum-Fed Mice

artículo científico publicado en 2020

The Relationship Between Dietary Macronutrients and Hepatic Telomere Length in Aging Mice

scientific article published on 01 March 2018

The Relationship between fenestrations, sieve plates and rafts in liver sinusoidal endothelial cells

artículo científico publicado en 2012

The aging liver. Drug clearance and an oxygen diffusion barrier hypothesis

artículo científico publicado en 1998

The association between antioxidant intake, dietary pattern and depressive symptoms in older Australian men: the Concord Health and Ageing in Men Project

artículo científico publicado en 2020

The association of alanine transaminase with aging, frailty, and mortality.

artículo científico publicado en 2010

The changing face of ageing research and practice in Australia over the last 50 years

artículo científico

The diet and the damage done

artículo científico publicado en 2019

The effect of Pseudomonas aeruginosa virulence factor, pyocyanin, on the liver sinusoidal endothelial cell

The effect of ageing on isoniazid pharmacokinetics and hepatotoxicity in Fischer 344 rats

artículo científico publicado en 2015

The effect of aging on acetaminophen pharmacokinetics, toxicity and Nrf2 in Fischer 344 rats

artículo científico publicado en 2013

The effect of aging on mitochondrial and cytosolic hepatic intrinsic death pathway and apoptosis associated proteins in Fischer 344 rats.

artículo científico publicado en 2015

The effect of aging on the immunohistochemistry of apolipoprotein E in the liver

scientific article published on 01 January 2004

The effect of aging on the response of isolated hepatocytes to hydrogen peroxide and tert-butyl hydroperoxide

artículo científico publicado en 2009

The effect of feeding and fasting on fenestrations in the liver sinusoidal endothelial cell

artículo científico publicado en 2010

The effect of meals at different mealtimes on blood pressure and symptoms in geriatric patients with postprandial hypotension

artículo científico publicado en 2005

The effect of old age on apolipoprotein E and its receptors in rat liver

scientific journal article

The effect of old age on liver oxygenation and the hepatic expression of VEGF and VEGFR2

artículo científico publicado en 2007

The effects of old age on hepatic stellate cells

artículo científico publicado en 2011

The effects of oxidative stress on the liver sieve

artículo científico publicado en 2004

The geometric framework reveals that a moderate-protein, high-carbohydrate intake is optimal for severe burn injury in mice

scientific article published on 27 January 2020

The hepatic pharmacokinetics of doxorubicin and liposomal doxorubicin

artículo científico publicado en 2004

The hepatic sinusoid in aging and cirrhosis: effects on hepatic substrate disposition and drug clearance.

artículo científico publicado en 2005

The impact of low-protein high-carbohydrate diets on aging and lifespan

artículo científico

The influence of old age and poloxamer-407 on the hepatic disposition of diazepam in the isolated perfused rat liver

artículo científico publicado en 2012

The influence of oxygen tension on the structure and function of isolated liver sinusoidal endothelial cells

artículo científico publicado en 2008

The liver sieve and atherosclerosis

artículo científico publicado en 2012

The liver sieve and gene therapy

artículo científico publicado en 2003

The nutritional geometry of liver disease including non-alcoholic fatty liver disease (NAFLD).

artículo científico publicado en 2017

The parkin gene S/N167 polymorphism in Australian Parkinson's disease patients and controls

article

The ratio of macronutrients, not caloric intake, dictates cardiometabolic health, aging, and longevity in ad libitum-fed mice

artículo científico publicado en 2014

The response of fenestrations, actin, and caveolin-1 to vascular endothelial growth factor in SK Hep1 cells

artículo científico publicado en 2008

The role of fat and lean mass in bone loss in older men: findings from the CHAMP study

artículo científico publicado en 2011

The scavenger endothelial cell: a new player in homeostasis and immunity

artículo científico

The vascular implications of post-prandial lipoprotein metabolism

artículo científico publicado en 2004

Thinking through the medication list - appropriate prescribing and deprescribing in robust and frail older patients.

artículo científico publicado en 2012

Three-dimensional structured illumination microscopy of liver sinusoidal endothelial cell fenestrations

artículo científico publicado en 2010

Total Physical Activity, Exercise Intensity, and Walking Speed as Predictors of All-Cause and Cause-Specific Mortality Over 7 Years in Older Men: The Concord Health and Aging in Men Project

artículo científico publicado en 2017

Toxicity of Passiflora incarnata L

article

U-shaped association between serum 25-hydroxyvitamin D and fracture risk in older men: results from the prospective population-based CHAMP study

artículo científico publicado en 2014

Ultrastructure of the liver microcirculation influences hepatic and systemic insulin activity and provides a mechanism for age-related insulin resistance

artículo científico publicado en 2016

Urinary incontinence and quality of life among older community-dwelling Australian men: the CHAMP study

artículo científico publicado en 2010

Validity of the 13C-caffeine breath test as a noninvasive, quantitative test of liver function

artículo científico publicado en 2003

Variability in response to medicines in older people: phenotypic and genotypic factors.

artículo científico publicado en 2009

Vitamin C modulates the metabolic and cytokine profiles, alleviates hepatic endoplasmic reticulum stress, and increases the life span of Gulo-/- mice

artículo científico publicado en 2016

Vitamin C restores healthy aging in a mouse model for Werner syndrome

artículo científico publicado en 2009

Vitamin D status among older community dwelling men living in a sunny country and associations with lifestyle factors: the Concord Health and Ageing in Men Project, Sydney, Australia

artículo científico publicado en 2013

Wash-in methodology and modeling to determine hepatocellular D-glucose transport in the perfused rat liver.

artículo científico publicado en 2004

Why do physicians choose to train in geriatric medicine?

Zeta class glutathione transferase polymorphisms and Parkinson's disease

artículo científico publicado en 2001

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