Lista de obras - Werner Weitschies - Dominio Público Uruguay

A Semi-mechanistic Modeling Strategy for Characterization of Regional Absorption Properties and Prospective Prediction of Plasma Concentrations Following Administration of New Modified Release Formulations

artículo científico publicado en 2011

A Semi-mechanistic Modeling Strategy to Link In Vitro and In Vivo Drug Release for Modified Release Formulations

artículo científico publicado en 2011

A biorelevant dissolution stress test device - background and experiences.

artículo científico publicado en 2010

A novel liquefied gas based oral controlled release drug delivery system for liquid drug formulations

artículo científico publicado en 2012

Advances in coronary stent technology--active drug-loaded stent surfaces for prevention of restenosis and improvement of biocompatibility.

artículo científico publicado en 2013

An Advanced Bioreactor Simulating Dynamic Physiological Conditions in the Human Ascending Colon: MimiCol<sup>3</sup>

artículo científico publicado en 2022

An International Network for Improving Health Properties of Food by Sharing our Knowledge on the Digestive Process

article

An automated system for monitoring and regulating the pH of bicarbonate buffers

artículo científico publicado en 2013

An oral-controlled release drug delivery system for liquid and semisolid drug formulations.

artículo científico publicado en 2011

Application of an automated small-scale in vitro transfer model to predict in vivo precipitation inhibition

scientific article published on 11 May 2019

Application of the GastroDuo as an in Vitro Dissolution Tool To Simulate the Gastric Emptying of the Postprandial Stomach

artículo científico publicado en 2019

Assessing gastrointestinal motility and disintegration profiles of magnetic tablets by a novel magnetic imaging device and gamma scintigraphy

artículo científico publicado en 2009

Automated small-scale in vitro transfer model as screening tool for the prediction of in vivo-dissolution and precipitation of poorly solubles

scientific article published on 12 December 2018

Bioavailability of amoxicillin and clavulanic acid from extended release tablets depends on intragastric tablet deposition and gastric emptying.

artículo científico publicado en 2008

CYP2D6 genotype and induction of intestinal drug transporters by rifampin predict presystemic clearance of carvedilol in healthy subjects.

artículo científico publicado en 2004

Changes in recovery due to drug product matrix ageing as a source of mass imbalances

artículo científico publicado en 2012

Characterization of the behavior of alginate-based microcapsules in vitro and in vivo.

artículo científico publicado en 2009

Characterization of the gastrointestinal transit and disintegration behavior of floating and sinking acid-resistant capsules using a novel MRI labeling technique

scientific article published on 10 January 2019

Close approximation of two platelet factor 4 tetramers by charge neutralization forms the antigens recognized by HIT antibodies

artículo científico publicado en 2006

Combined Application of MRI and the Salivary Tracer Technique to Determine the in Vivo Disintegration Time of Immediate Release Formulation Administered to Healthy, Fasted Subjects

artículo científico publicado en 2019

Comparison of In Vitro and In Vivo Results Using the GastroDuo and the Salivary Tracer Technique: Immediate Release Dosage Forms under Fasting Conditions

scientific article published on 07 December 2019

Comparison of dissolution profiles obtained from nifedipine extended release once a day products using different dissolution test apparatuses.

artículo científico publicado en 2009

Concentration of the macrolide antibiotic tulathromycin in broncho-alveolar cells is influenced by comedication of rifampicin in foals

artículo científico publicado en 2009

Design and characterization of a novel 3D printed pressure-controlled drug delivery system

artículo científico publicado en 2019

Design of biorelevant test setups for the prediction of diclofenac in vivo features after oral administration

artículo científico publicado en 2013

Determination of energy barrier distributions of magnetic nanoparticles by temperature dependent magnetorelaxometry

artículo científico publicado en 2003

Determination of permeability coefficients of ophthalmic drugs through different layers of porcine, rabbit and bovine eyes

artículo científico publicado en 2012

Determination of the disintegration behavior of magnetically marked tablets

scientific article published on 01 September 2001

Determination of the magneto-optical relaxation of magnetic nanoparticles as a homogeneous immunoassay

artículo científico publicado en 2007

Development of a dual extrusion printing technique for an acid- and thermo-labile drug

article

Development of a method for magnetic labeling of platelets

artículo científico publicado en 2011

Development of a vessel-simulating flow-through cell method for the in vitro evaluation of release and distribution from drug-eluting stents

artículo científico publicado en 2008

Development of an oral vaccine for immunisation of rainbow trout (Oncorhynchus mykiss) against viral haemorrhagic septicaemia.

artículo científico publicado en 2007

Development of hydrophobized alginate hydrogels for the vessel-simulating flow-through cell and their usage for biorelevant drug-eluting stent testing.

artículo científico publicado en 2013

Development of oral taste masked diclofenac formulations using a taste sensing system.

artículo científico publicado en 2012

Differential interaction of magnetic nanoparticles with tumor cells and peripheral blood cells

artículo científico publicado en 2006

Direct visualization and identification of biofunctionalized nanoparticles using a magnetic atomic force microscope.

artículo científico publicado en 2011

Disposition and antimuscarinic effects of the urinary bladder spasmolytics propiverine: influence of dosage forms and circadian-time rhythms.

artículo científico publicado en 2008

Disposition and sterol-lowering effect of ezetimibe are influenced by single-dose coadministration of rifampin, an inhibitor of multidrug transport proteins

artículo científico publicado en 2006

Disposition and sterol-lowering effect of ezetimibe in multidrug resistance-associated protein 2-deficient rats

artículo científico publicado en 2006

Drug interactions between the immunosuppressant tacrolimus and the cholesterol absorption inhibitor ezetimibe in healthy volunteers.

artículo científico publicado en 2011

Effect of Coadministered Water on the In Vivo Performance of Oral Formulations Containing N-Acetylcysteine: An In Vitro Approach Using the Dynamic Open Flow-Through Test Apparatus

artículo científico publicado en 2017

Effects of non-ionic surfactants on cytochrome P450-mediated metabolism in vitro.

artículo científico publicado en 2011

Effects of non-ionic surfactants on in vitro triglyceride digestion and their susceptibility to digestion by pancreatic enzymes.

artículo científico publicado en 2010

Esophageal transit of solid drug forms depends on body position, swallowing volume and pharyngeal propulsion velocity — a magnetic marker monitoring (MMM) study

Evaluation of consultation in community pharmacies with mystery shoppers

artículo científico publicado en 2007

Examination of drug release and distribution from drug-eluting stents with a vessel-simulating flow-through cell

artículo científico publicado en 2010

Examination of steroid release from screw-in pacing leads

artículo científico publicado en 2012

Exploring the Effect of Esomeprazole on Gastric and Duodenal Fluid Volumes and Absorption of Ritonavir

scientific article published on 17 July 2020

Foreword for the JPP special issue 'Recent innovations in dissolution testing'

artículo científico publicado en 2012

Gastric Emptying and Small Bowel Water Content after Administration of Grapefruit Juice Compared to Water and Isocaloric Solutions of Glucose and Fructose: A Four-Way Crossover MRI Pilot Study in Healthy Subjects

artículo científico publicado en 2018

Gastric Water Emptying under Fed State Clinical Trial Conditions Is as Fast as under Fasted Conditions.

artículo científico publicado en 2017

Heparin-induced thrombocytopenia--therapeutic concentrations of danaparoid, unlike fondaparinux and direct thrombin inhibitors, inhibit formation of platelet factor 4-heparin complexes

artículo científico publicado en 2008

Heparin-induced thrombocytopenia: a stoichiometry-based model to explain the differing immunogenicities of unfractionated heparin, low-molecular-weight heparin, and fondaparinux in different clinical settings

artículo científico publicado en 2008

Hepatic uptake of the magnetic resonance imaging contrast agent Gd-EOB-DTPA: role of human organic anion transporters.

artículo científico publicado en 2010

High-resolution monitoring of the gastrointestinal transit of a magnetically marked capsule

scientific article published on 01 November 1997

Impact of the intragastric location of extended release tablets on food interactions

artículo científico publicado en 2005

Improved Prediction of in Vivo Supersaturation and Precipitation of Poorly Soluble Weakly Basic Drugs Using a Biorelevant Bicarbonate Buffer in a Gastrointestinal Transfer Model

artículo científico publicado en 2019

In vitro dissolution testing of drug-eluting stents.

artículo científico publicado en 2013

In vitro simulation of realistic gastric pressure profiles.

artículo científico publicado en 2017

In vivo imaging of drug delivery systems in the gastrointestinal tract.

artículo científico publicado en 2011

In-line derivative spectroscopy as a promising application to a small-scale in vitro transfer model in biorelevant supersaturation and precipitation testing

scientific article published on 30 July 2018

In-vitro dissolution methods for controlled release parenterals and their applicability to drug-eluting stent testing.

artículo científico

Individualized, Additively Manufactured Drug-Releasing External Ear Canal Implant for Prevention of Postoperative Restenosis: Development, In Vitro Testing, and Proof of Concept in an Individual Curative Trial

artículo científico publicado en 2022

Influence of the test method on in vitro drug release from intravitreal model implants containing dexamethasone or fluorescein sodium in poly (d,l-lactide-co-glycolide) or polycaprolactone.

artículo científico publicado en 2018

Intestinal expression of P-glycoprotein (ABCB1), multidrug resistance associated protein 2 (ABCC2), and uridine diphosphate-glucuronosyltransferase 1A1 predicts the disposition and modulates the effects of the cholesterol absorption inhibitor ezetim

artículo científico publicado en 2006

Investigating the stability of the nonionic surfactants tocopheryl polyethylene glycol succinate and sucrose laurate by HPLC-MS, DAD, and CAD.

artículo científico publicado en 2011

Investigation of gastrointestinal transport by magnetic marker localization

artículo científico publicado en 2002

Irregular absorption profiles observed from diclofenac extended release tablets can be predicted using a dissolution test apparatus that mimics in vivo physical stresses

artículo científico publicado en 2008

Magnesium used in bioabsorbable stents controls smooth muscle cell proliferation and stimulates endothelial cells in vitro

artículo científico publicado en 2011

Magnetic marker monitoring of disintegrating capsules.

artículo científico publicado en 2001

Magnetic marker monitoring of esophageal, gastric and duodenal transit of non-disintegrating capsules

artículo científico publicado en 1999

Magnetic marker monitoring: high resolution real-time tracking of oral solid dosage forms in the gastrointestinal tract.

artículo científico publicado en 2009

Magnetic markers as a noninvasive tool to monitor gastrointestinal transit.

artículo científico publicado en 1994

Magnetic markers in the gastrointestinal tract--a new method for the study of absorption of solid oral drugs

artículo científico publicado en 1990

Magnetorelaxometry—a new binding specific detection method based on magnetic nanoparticles

article published in 2002

Mechanistic modeling of a magnetic marker monitoring study linking gastrointestinal tablet transit, in vivo drug release, and pharmacokinetics.

artículo científico publicado en 2009

N-glycosylation of ABC transporters is associated with functional activity in sandwich-cultured rat hepatocytes.

artículo científico publicado en 2010

Nanoparticle Composition of a Ferrofluid and Its Effects on the Magnetic Properties

article

Oesophageal transport of solid dosage forms depends on body position, swallowing volume and pharyngeal propulsion velocity

artículo científico publicado en 2004

Preparation and characterization of magnetizable aerosols.

artículo científico publicado en 2012

Response

Separation of delta6- and delta9,11-estradiol: analytical method development, validation and practical application.

artículo científico publicado en 2013

Simulating the postprandial stomach: biorelevant test methods for the estimation of intragastric drug dissolution.

artículo científico publicado en 2013

Stability of the non-ionic surfactant polysorbate 80 investigated by HPLC-MS and charged aerosol detector

artículo científico publicado en 2011

The Vitreous Model - a new in vitro test method simulating the vitreous body

artículo científico publicado en 2012

The role of individual gastric emptying of pellets in the prediction of diclofenac in vivo dissolution.

artículo científico publicado en 2013

The talinolol double-peak phenomenon is likely caused by presystemic processing after uptake from gut lumen

artículo científico publicado en 2005

Variability of intestinal expression of P-glycoprotein in healthy volunteers as described by absorption of talinolol from four bioequivalent tablets

artículo científico publicado en 2003

Visualization of hepatic uptake transporter function in healthy subjects by using gadoxetic acid-enhanced MR imaging

artículo científico publicado en 2012

[Magnets instead of radioisotope: pills in the gastrointestinal tract]

artículo científico publicado en 2000

[Significance of drug transporter for the internal medicine clinic]

artículo científico publicado en 2003

[The challenge of patient consultation and pharmaceutical development: bisphosphonate in solid dosage forms]

scientific article published on 01 January 2001

Lista de obras de Werner Weitschies

A Semi-mechanistic Modeling Strategy for Characterization of Regional Absorption Properties and Prospective Prediction of Plasma Concentrations Following Administration of New Modified Release Formulations

A Semi-mechanistic Modeling Strategy to Link In Vitro and In Vivo Drug Release for Modified Release Formulations

A biorelevant dissolution stress test device - background and experiences.

A novel liquefied gas based oral controlled release drug delivery system for liquid drug formulations

Advances in coronary stent technology--active drug-loaded stent surfaces for prevention of restenosis and improvement of biocompatibility.

An Advanced Bioreactor Simulating Dynamic Physiological Conditions in the Human Ascending Colon: MimiCol<sup>3</sup>

An International Network for Improving Health Properties of Food by Sharing our Knowledge on the Digestive Process

An automated system for monitoring and regulating the pH of bicarbonate buffers

An oral-controlled release drug delivery system for liquid and semisolid drug formulations.

Application of an automated small-scale in vitro transfer model to predict in vivo precipitation inhibition

Application of the GastroDuo as an in Vitro Dissolution Tool To Simulate the Gastric Emptying of the Postprandial Stomach

Assessing gastrointestinal motility and disintegration profiles of magnetic tablets by a novel magnetic imaging device and gamma scintigraphy

Automated small-scale in vitro transfer model as screening tool for the prediction of in vivo-dissolution and precipitation of poorly solubles

Bioavailability of amoxicillin and clavulanic acid from extended release tablets depends on intragastric tablet deposition and gastric emptying.

CYP2D6 genotype and induction of intestinal drug transporters by rifampin predict presystemic clearance of carvedilol in healthy subjects.

Changes in recovery due to drug product matrix ageing as a source of mass imbalances

Characterization of the behavior of alginate-based microcapsules in vitro and in vivo.

Characterization of the gastrointestinal transit and disintegration behavior of floating and sinking acid-resistant capsules using a novel MRI labeling technique

Close approximation of two platelet factor 4 tetramers by charge neutralization forms the antigens recognized by HIT antibodies

Combined Application of MRI and the Salivary Tracer Technique to Determine the in Vivo Disintegration Time of Immediate Release Formulation Administered to Healthy, Fasted Subjects

Comparison of In Vitro and In Vivo Results Using the GastroDuo and the Salivary Tracer Technique: Immediate Release Dosage Forms under Fasting Conditions

Comparison of dissolution profiles obtained from nifedipine extended release once a day products using different dissolution test apparatuses.

Concentration of the macrolide antibiotic tulathromycin in broncho-alveolar cells is influenced by comedication of rifampicin in foals

Design and characterization of a novel 3D printed pressure-controlled drug delivery system

Design of biorelevant test setups for the prediction of diclofenac in vivo features after oral administration

Determination of energy barrier distributions of magnetic nanoparticles by temperature dependent magnetorelaxometry

Determination of permeability coefficients of ophthalmic drugs through different layers of porcine, rabbit and bovine eyes

Determination of the disintegration behavior of magnetically marked tablets

Determination of the magneto-optical relaxation of magnetic nanoparticles as a homogeneous immunoassay

Development of a dual extrusion printing technique for an acid- and thermo-labile drug

Development of a method for magnetic labeling of platelets

Development of a vessel-simulating flow-through cell method for the in vitro evaluation of release and distribution from drug-eluting stents

Development of an oral vaccine for immunisation of rainbow trout (Oncorhynchus mykiss) against viral haemorrhagic septicaemia.

Development of hydrophobized alginate hydrogels for the vessel-simulating flow-through cell and their usage for biorelevant drug-eluting stent testing.

Development of oral taste masked diclofenac formulations using a taste sensing system.

Differential interaction of magnetic nanoparticles with tumor cells and peripheral blood cells

Direct visualization and identification of biofunctionalized nanoparticles using a magnetic atomic force microscope.

Disposition and antimuscarinic effects of the urinary bladder spasmolytics propiverine: influence of dosage forms and circadian-time rhythms.

Disposition and sterol-lowering effect of ezetimibe are influenced by single-dose coadministration of rifampin, an inhibitor of multidrug transport proteins

Disposition and sterol-lowering effect of ezetimibe in multidrug resistance-associated protein 2-deficient rats

Drug interactions between the immunosuppressant tacrolimus and the cholesterol absorption inhibitor ezetimibe in healthy volunteers.

Effect of Coadministered Water on the In Vivo Performance of Oral Formulations Containing N-Acetylcysteine: An In Vitro Approach Using the Dynamic Open Flow-Through Test Apparatus

Effects of non-ionic surfactants on cytochrome P450-mediated metabolism in vitro.

Effects of non-ionic surfactants on in vitro triglyceride digestion and their susceptibility to digestion by pancreatic enzymes.

Esophageal transit of solid drug forms depends on body position, swallowing volume and pharyngeal propulsion velocity — a magnetic marker monitoring (MMM) study

Evaluation of consultation in community pharmacies with mystery shoppers

Examination of drug release and distribution from drug-eluting stents with a vessel-simulating flow-through cell

Examination of steroid release from screw-in pacing leads

Exploring the Effect of Esomeprazole on Gastric and Duodenal Fluid Volumes and Absorption of Ritonavir

Foreword for the JPP special issue 'Recent innovations in dissolution testing'

Gastric Emptying and Small Bowel Water Content after Administration of Grapefruit Juice Compared to Water and Isocaloric Solutions of Glucose and Fructose: A Four-Way Crossover MRI Pilot Study in Healthy Subjects

Gastric Water Emptying under Fed State Clinical Trial Conditions Is as Fast as under Fasted Conditions.

Heparin-induced thrombocytopenia--therapeutic concentrations of danaparoid, unlike fondaparinux and direct thrombin inhibitors, inhibit formation of platelet factor 4-heparin complexes

Heparin-induced thrombocytopenia: a stoichiometry-based model to explain the differing immunogenicities of unfractionated heparin, low-molecular-weight heparin, and fondaparinux in different clinical settings

Hepatic uptake of the magnetic resonance imaging contrast agent Gd-EOB-DTPA: role of human organic anion transporters.

High-resolution monitoring of the gastrointestinal transit of a magnetically marked capsule

Impact of the intragastric location of extended release tablets on food interactions

Improved Prediction of in Vivo Supersaturation and Precipitation of Poorly Soluble Weakly Basic Drugs Using a Biorelevant Bicarbonate Buffer in a Gastrointestinal Transfer Model

In vitro dissolution testing of drug-eluting stents.

In vitro simulation of realistic gastric pressure profiles.

In vivo imaging of drug delivery systems in the gastrointestinal tract.

In-line derivative spectroscopy as a promising application to a small-scale in vitro transfer model in biorelevant supersaturation and precipitation testing

In-vitro dissolution methods for controlled release parenterals and their applicability to drug-eluting stent testing.

Individualized, Additively Manufactured Drug-Releasing External Ear Canal Implant for Prevention of Postoperative Restenosis: Development, In Vitro Testing, and Proof of Concept in an Individual Curative Trial

Influence of the test method on in vitro drug release from intravitreal model implants containing dexamethasone or fluorescein sodium in poly (d,l-lactide-co-glycolide) or polycaprolactone.

Intestinal expression of P-glycoprotein (ABCB1), multidrug resistance associated protein 2 (ABCC2), and uridine diphosphate-glucuronosyltransferase 1A1 predicts the disposition and modulates the effects of the cholesterol absorption inhibitor ezetim

Investigating the stability of the nonionic surfactants tocopheryl polyethylene glycol succinate and sucrose laurate by HPLC-MS, DAD, and CAD.

Investigation of gastrointestinal transport by magnetic marker localization

Irregular absorption profiles observed from diclofenac extended release tablets can be predicted using a dissolution test apparatus that mimics in vivo physical stresses

Magnesium used in bioabsorbable stents controls smooth muscle cell proliferation and stimulates endothelial cells in vitro

Magnetic marker monitoring of disintegrating capsules.

Magnetic marker monitoring of esophageal, gastric and duodenal transit of non-disintegrating capsules

Magnetic marker monitoring: high resolution real-time tracking of oral solid dosage forms in the gastrointestinal tract.

Magnetic markers as a noninvasive tool to monitor gastrointestinal transit.

Magnetic markers in the gastrointestinal tract--a new method for the study of absorption of solid oral drugs

Magnetorelaxometry—a new binding specific detection method based on magnetic nanoparticles

Mechanistic modeling of a magnetic marker monitoring study linking gastrointestinal tablet transit, in vivo drug release, and pharmacokinetics.

N-glycosylation of ABC transporters is associated with functional activity in sandwich-cultured rat hepatocytes.

Nanoparticle Composition of a Ferrofluid and Its Effects on the Magnetic Properties