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Lista de obras de Sébastien Lacroix-Desmazes

"Rational vaccine design" for HIV should take into account the adaptive potential of polyreactive antibodies

artículo científico publicado en 2011

A cellular viewpoint of anti-FVIII immune response in hemophilia A.

artículo científico publicado en 2009

A cryptic polyreactive antibody recognizes distinct clades of HIV-1 glycoprotein 120 by an identical binding mechanism

artículo científico publicado en 2014

A human FVIII inhibitor modulates FVIII surface electrostatics at a VWF-binding site distant from its epitope.

artículo científico publicado en 2010

A novel molecular analysis of genes encoding catalytic antibodies

artículo científico publicado en 2012

A role for exposed mannosylations in presentation of human therapeutic self-proteins to CD4+ T lymphocytes

artículo científico publicado en 2007

Absence of a neutralizing antibody response to humanized cobra venom factor in mice

artículo científico publicado en 2018

Achievements, challenges and unmet needs for haemophilia patients with inhibitors: Report from a symposium in Paris, France on 20 November 2014.

artículo científico publicado en 2016

Acquired haemophilia A in early pregnancy associated with Plasmodium vivax malaria and hyperthyroidism

artículo científico publicado en 2007

Acquired protein S deficiency leads to obliterative portal venopathy and to compensatory nodular regenerative hyperplasia in HIV-infected patients

article

Activation state of platelets in experimental severe hemophilia A.

artículo científico publicado en 2012

Affinity-purified respiratory syncytial virus antibodies from intravenous immunoglobulin exert potent antibody-dependent cellular cytotoxicity

artículo científico publicado en 2013

Alloantibodies to therapeutic factor VIII in hemophilia A: the role of von Willebrand factor in regulating factor VIII immunogenicity

artículo científico publicado en 2015

Alterations of self-reactive antibody repertoires in HIV disease: An insight into the role of T cells in the selection of autoreactive B cells

article

Altered antibody repertoires of plasma IgM and IgG toward nonself antigens in patients with warm autoimmune hemolytic anemia

scientific article published on 01 April 2001

Altered control of self-reactive IgG by autologous IgM in patients with warm autoimmune hemolytic anemia

artículo científico publicado en 2000

Amelioration of differentiation of dendritic cells from CVID patients by intravenous immunoglobulin

Analysis of antibody reactivities toward self antigens of IgM of patients with Waldenström's macroglobulinemia

artículo científico publicado en 1997

Analysis of self-reactive antibody repertoires in normal pregnancy

artículo científico publicado en 1998

Analysis of the natural human IgG antibody repertoire: life-long stability of reactivities towards self antigens contrasts with age-dependent diversification of reactivities against bacterial antigens

scientific article published on 01 September 1995

Analysis of the normal human IgG antibody repertoire. Evidence that IgG autoantibodies of healthy adults recognize a limited and conserved set of protein antigens in homologous tissues

artículo científico publicado en 1995

Antibodies to the FVIII light chain that neutralize FVIII procoagulant activity are present in plasma of nonresponder patients with severe hemophilia A and in normal polyclonal human IgG.

artículo científico publicado en 2000

Antibodies use heme as a cofactor to extend their pathogen elimination activity and to acquire new effector functions

scientific article published on 18 July 2007

Antibodies with hydrolytic activity towards factor VIII in patients with hemophilia A.

artículo científico publicado en 2002

Antibody polyreactivity in health and disease: statu variabilis

artículo científico

Antibody profile in Indian severe haemophilia A patients with and without FVIII inhibitors

artículo científico publicado en 2015

Antibody-mediated catalysis: induction and therapeutic relevance

artículo científico publicado en 2012

Anticorps catalytiques ou abzymes

artículo científico publicado en 2003

Auditing protein therapeutics management by professional APCs: toward prevention of immune responses against therapeutic proteins.

artículo científico publicado en 2008

Autoantibodies to factor VIII with catalytic activity.

artículo científico publicado en 2003

Autoantibodies to factor VIII.

artículo científico publicado en 2002

Autoantibodies to heat shock protein 90 in the human natural antibody repertoire

scientific article published on 01 May 2002

Autoantibodies with enzymatic properties in human autoimmune diseases

artículo científico publicado en 2011

Autoimmunity as a predisposition for infectious diseases

artículo científico publicado en 2010

Bortezomib delays the onset of factor VIII inhibitors in experimental hemophilia A, but fails to eliminate established anti-factor VIII IgG-producing cells

artículo científico publicado en 2011

Breaking the law: unconventional strategies for antibody diversification

scientific article published on 01 June 2019

Broad alterations of self-reactive antibody-repertoires of plasma IgM and IgG in B-cell chronic lymphocytic leukemia (B-CLL) and B-CLL related target-restricted autoimmunity

artículo científico publicado en 2001

CD4+CD25+ regulatory T cell-mediated changes in the expression of endocytic receptors and endocytosis process of human dendritic cells

artículo científico publicado en 2011

CD4+CD25+ regulatory T cells modulate human dendritic cell chemokines via multiple mechanisms: comment on the article by Kolar et al

scientific article published on 01 September 2009

Catalytic IgG from patients with hemophilia A inactivate therapeutic factor VIII.

artículo científico publicado en 2006

Catalytic activity of antibodies against factor VIII in patients with hemophilia A.

artículo científico publicado en 1999

Catalytic antibodies and severe sepsis.

artículo científico publicado en 2005

Catalytic antibodies in patients with systemic lupus erythematosus

scientific article published on 07 August 2018

Catalytic antibodies to factor VIII in haemophilia A.

artículo científico publicado en 2003

Common variable immunodeficiency is associated with defective functions of dendritic cells

artículo científico publicado en 2004

Comparison of the immunogenicity of different therapeutic preparations of human factor VIII in the murine model of hemophilia A.

artículo científico publicado en 2007

Complement C3 is a novel modulator of the anti-FVIII immune response

artículo científico publicado en 2017

Contribution of myeloid dendritic cells to type I interferon-induced cytokines and chemokines

artículo científico publicado en 2010

Correction to Mechanism and Functional Implications of the Heme-Induced Binding Promiscuity of IgE

artículo científico publicado en 2015

Cryptic polyreactivity of IgG expressed by splenic marginal zone B-cell lymphoma.

artículo científico publicado en 2014

Cutting edge: human CD4+CD25+ T cells restrain the maturation and antigen-presenting function of dendritic cells

artículo científico publicado en 2004

Defective self-reactive antibody repertoire of serum IgM in patients with hyper-IgM syndrome

artículo científico publicado en 1999

Dendritic Cells in Autoimmune Diseases

Dendritic cells and autoimmunity

artículo científico publicado en 2004

Design of clinical trials for new products in hemophilia: communication from the SSC of the ISTH.

artículo científico publicado en 2015

Designed ankyrin repeat proteins: a new approach to mimic complex antigens for diagnostic purposes?

artículo científico publicado en 2013

Development of inhibitory antibodies to therapeutic factor VIII in severe hemophilia A is associated with microsatellite polymorphisms in the HMOX1 promoter.

scientific article published on 28 May 2013

Diversification post-traductionnelle de la spécificité des immunoglobulines

artículo científico publicado en 2013

Do proteolytic antibodies complete the panoply of the autoimmune response in acquired haemophilia A?

artículo científico publicado en 2011

Dynamics of factor VIII interactions determine its immunologic fate in hemophilia A.

artículo científico publicado en 2008

Effect of IVIg on human dendritic cell-mediated antigen uptake and presentation: Role of lipid accumulation

artículo científico publicado en 2012

Efficacy of regulatory T-cell immunotherapy: are inflammatory cytokines key determinants?

artículo científico publicado en 2008

Emerging benefits of Fc fusion technology in the context of recombinant factor VIII replacement therapy

scientific article published on 03 September 2020

Endocytic receptor for pro-coagulant factor VIII: Relevance to inhibitor formation

scientific article published on 30 September 2010

Expansion of CD4+CD25+ regulatory T cells by intravenous immunoglobulin: a critical factor in controlling experimental autoimmune encephalomyelitis

artículo científico publicado en 2007

Exploitation of rolling circle amplification for the construction of large phage-display antibody libraries

artículo científico publicado en 2014

Exposure of IgG to an acidic environment results in molecular modifications and in enhanced protective activity in sepsis.

artículo científico publicado en 2010

Factor VIII bypasses CD91/LRP for endocytosis by dendritic cells leading to T-cell activation.

artículo científico publicado en 2008

Factor VIII hydrolysis mediated by anti-factor VIII autoantibodies in acquired hemophilia.

artículo científico publicado en 2008

Factor VIII inhibitor with catalytic activity towards factor VIII

scientific article published on 01 January 2000

Factor VIII inhibitor with catalytic activity towards factor VIII.

artículo científico publicado en 2000

Factor VIII-hydrolyzing IgG in acquired and congenital hemophilia

artículo científico publicado en 2009

Ferrous ions and reactive oxygen species increase antigen-binding and anti-inflammatory activities of immunoglobulin G

artículo científico publicado en 2005

Functional variability of antibodies upon oxidative processes

artículo científico publicado en 2008

Gain of function of immunoglobulins after partial unfolding or cofactor binding ⬇️

artículo científico publicado el 9 de abril de 2013

Generation of Catalytic Antibodies Is an Intrinsic Property of an Individual's Immune System: A Study on a Large Cohort of Renal Transplant Patients.

artículo científico publicado en 2016

Haemarthrosis and arthropathy do not favour the development of factor VIII inhibitors in severe haemophilia A mice

artículo científico publicado en 2014

Heme binds to factor VIII and inhibits its interaction with activated factor IX.

artículo científico publicado en 2012

Heme interacts with c1q and inhibits the classical complement pathway

artículo científico publicado en 2011

Heme: Modulator of Plasma Systems in Hemolytic Diseases

artículo científico publicado en 2016

Heterogeneous antigen recognition behavior of induced polyspecific antibodies

scientific article published on 22 June 2010

High levels of catalytic antibodies correlate with favorable outcome in sepsis.

artículo científico publicado en 2005

Hydrolysis of coagulation factors by circulating IgG is associated with a reduced risk for chronic allograft nephropathy in renal transplanted patients

artículo científico publicado en 2008

IVIg treatment reduces catalytic antibody titers of renal transplanted patients

artículo científico publicado en 2013

Idiopathic membranous glomerulonephritis is associated with altered patterns of self-reactive IgM and IgG antibody repertoires

scientific article published on 01 November 2001

IgG-cleaving endopeptidase enables in vivo gene therapy in the presence of anti-AAV neutralizing antibodies

artículo científico publicado en 2020

Immune response against therapeutic factor VIII in hemophilia A patients--a survey of probable risk factors.

artículo científico publicado en 2007

Immunogenicity of long-lasting recombinant factor VIII products

artículo científico

Immunoglobulins and the regulation of autoimmunity through the immune network.

artículo científico publicado en 1996

Immunological defects after suicide gene therapy of experimental graft-versus-host disease.

artículo científico publicado en 1999

Immunomodulation by intravenous immunoglobulin: role of regulatory T cells

artículo científico publicado en 2010

Immunomodulation of autoimmunity by intravenous immunoglobulin through interaction with immune networks

artículo científico publicado en 2002

Immunoprotective effect of von Willebrand factor towards therapeutic factor VIII in experimental haemophilia A.

artículo científico publicado en 2011

Impact of Antigen Density on the Binding Mechanism of IgG Antibodies

artículo científico publicado en 2017

Impact of polymorphisms of the major histocompatibility complex class II, interleukin-10, tumor necrosis factor-alpha and cytotoxic T-lymphocyte antigen-4 genes on inhibitor development in severe hemophilia A.

artículo científico publicado en 2009

Important parameters for evaluation of antibody avidity by immunosorbent assay

artículo científico publicado en 2011

In silico calculated affinity of FVIII-derived peptides for HLA class II alleles predicts inhibitor development in haemophilia A patients with missense mutations in the F8 gene

artículo científico publicado en 2013

Induction of heme oxygenase-1 in factor VIII-deficient mice reduces the immune response to therapeutic factor VIII.

artículo científico publicado en 2009

Inhibition of differentiation, amplification, and function of human TH17 cells by intravenous immunoglobulin

artículo científico publicado en 2011

Inhibition of maturation and function of dendritic cells by intravenous immunoglobulin

artículo científico publicado en 2002

Inhibitor development.

artículo científico publicado en 2008

Inhibitors of factor VIII in hemophilia

artículo científico publicado en 2009

Inhibitors-Recent insights

scientific article published on 30 June 2020

Inhibitory effect of IVIG on IL-17 production by Th17 cells is independent of anti-IL-17 antibodies in the immunoglobulin preparations

artículo científico publicado en 2012

Innovating immune tolerance induction for haemophilia.

artículo científico publicado en 2016

Insight into the mechanism of the acquired antibody auto-reactivity.

scientific article published on 18 April 2008

Intravenous Immunoglobulins in Autoimmune and Inflammatory Diseases: A Mechanistic Perspective

artículo científico publicado en 2007

Intravenous gammaglobulin inhibits encephalitogenic potential of pathogenic T cells and interferes with their trafficking to the central nervous system, implicating sphingosine-1 phosphate receptor 1-mammalian target of rapamycin axis

artículo científico publicado en 2013

Intravenous immunoglobulin abrogates dendritic cell differentiation induced by interferon-? present in serum from patients with systemic lupus erythematosus

scientific article published on 01 December 2003

Intravenous immunoglobulin and dendritic cells.

artículo científico publicado en 2005

Intravenous immunoglobulin and immune response

article

Intravenous immunoglobulin for infectious diseases: back to the pre-antibiotic and passive prophylaxis era?

artículo científico publicado en 2004

Intravenous immunoglobulin for infectious diseases: tailor-made or universal?

artículo científico publicado en 2003

Intravenous immunoglobulin in autoimmune and inflammatory diseases: more than mere transfer of antibodies.

artículo científico publicado en 2007

Intravenous immunoglobulin in autoimmune disorders: an insight into the immunoregulatory mechanisms.

artículo científico publicado en 2005

Intravenous immunoglobulin in neurological disorders: a mechanistic perspective

artículo científico publicado en 2005

Intravenous immunoglobulin induces proliferation and immunoglobulin synthesis from B cells of patients with common variable immunodeficiency: A mechanism underlying the beneficial effect of IVIg in primary immunodeficiencies

article

Intravenous immunoglobulin: an update on the clinical use and mechanisms of action.

artículo científico publicado en 2007

Intravenous immunoglobulins in immunodeficiencies: more than mere replacement therapy

artículo científico publicado en 2011

Japanese encephalitis virus expands regulatory T cells by increasing the expression of PD-L1 on dendritic cells

artículo científico publicado en 2014

Key insights to understand the immunogenicity of FVIII products

artículo científico publicado en 2016

Kinetics and thermodynamics of interaction of coagulation factor VIII with a pathogenic human antibody

artículo científico publicado en 2009

Mannose-sensitive receptors mediate the uptake of factor VIII therapeutics by human dendritic cells

artículo científico publicado en 2012

Maternally transferred anti-factor VIII IgG reduce the anti-factor VIII humoral immune response in factor VIII-deficient mice.

artículo científico publicado en 2010

Materno-Fetal Transfer of Preproinsulin Through the Neonatal Fc Receptor Prevents Autoimmune Diabetes

artículo científico publicado en 2015

Mechanism and functional implications of the heme-induced binding promiscuity of IgE.

artículo científico publicado en 2015

Mechanisms of action of intravenous immunoglobulin in autoimmune and inflammatory diseases

artículo científico publicado en 2003

Mechanisms of action of intravenous immunoglobulin in autoimmune and inflammatory diseases.

artículo científico publicado en 2003

Methods for Posttranslational Induction of Polyreactivity of Antibodies

artículo científico publicado en 2017

Modulation of autoimmune responses by intravenous immunoglobulin (IVIg).

artículo científico publicado en 1997

Modulation of dendritic cell maturation and function by B lymphocytes

artículo científico publicado en 2005

Modulation of human dendritic cell maturation and function by natural IgG antibodies

artículo científico publicado en 2008

Molecular basis for bacterial peptidoglycan recognition by LysM domains

artículo científico publicado en 2014

Molecular characterization of human B domain-specific anti-factor VIII monoclonal antibodies generated in transgenic mice

scientific article published on 01 July 2007

Monoclonal antibody and intravenous immunoglobulin therapy for rheumatic diseases: rationale and mechanisms of action.

artículo científico publicado en 2007

Monoepitopic anti-FVIII T-cell response

artículo científico publicado en 2016

Multitarget selection of catalytic antibodies with β-lactamase activity using phage display

artículo científico publicado en 2017

Natural Autoantibodies to Fcγ Receptors in Intravenous Immunoglobulins

artículo científico publicado en 2014

Natural and Induced Antibody Polyreactivity.

artículo científico

Natural antibodies sustain differentiation and maturation of human dendritic cells

scholarly article

Natural antibodies to factor VIII.

artículo científico publicado en 2000

Natural autoantibodies: immune homeostasis and therapeutic intervention

artículo científico publicado en 2005

Natural human polyreactive IgM induce apoptosis of lymphoid cell lines and human peripheral blood mononuclear cells.

artículo científico publicado en 2004

Natural recognition repertoire and the evolutionary emergence of the combinatorial immune system

artículo científico publicado en 2002

Neutralization of Japanese Encephalitis Virus by heme-induced broadly reactive human monoclonal antibody

artículo científico publicado en 2015

Noncanonical Functions of Antibodies

scientific article published on 06 April 2020

Novel cellular and molecular mechanisms of induction of immune responses by aluminum adjuvants

artículo científico publicado en 2009

Novel therapeutic strategies for multiple sclerosis: potential of intravenous immunoglobulin

artículo científico publicado en 2009

Oxidation of factor VIII increases its immunogenicity in mice with severe hemophilia A.

artículo científico publicado en 2018

Parameters that influence the prediction of epidemiological benefits of more-effective tuberculosis vaccines, drugs, and diagnosis

artículo científico publicado en 2009

Pathophysiology of catalytic antibodies

artículo científico publicado en 2005

Pathophysiology of inhibitors to factor VIII in patients with haemophilia A.

artículo científico publicado en 2002

Peptide decoys selected by phage display block in vitro and in vivo activity of a human anti-FVIII inhibitor.

artículo científico publicado en 2003

Physiopathology of catalytic antibodies: the case for factor VIII-hydrolyzing immunoglobulin G.

artículo científico publicado en 2006

Polyreactivity of disease-associated anti-RBC IgG autoantibodies of patients with warm autoimmune haemolytic anaemia and natural anti-RBC IgG autoantibodies of healthy individuals

scientific article published on 01 August 2000

Predictive immunogenicity of Refacto AF.

artículo científico publicado en 2013

Prevalence and gene characteristics of antibodies with cofactor-induced HIV-1 specificity.

artículo científico publicado en 2015

Proteolytic antibodies activate factor IX in patients with acquired hemophilia.

artículo científico publicado en 2010

Red blood cell transfusions are associated with alterations in self-reactive antibody repertoires of plasma IgM and IgG, independent of the presence of a specific immune response toward RBC antigens

artículo científico publicado en 2002

Regulation of immune responses to protein therapeutics by transplacental induction of T cell tolerance

artículo científico publicado en 2015

Relationship between natural and heme-mediated antibody polyreactivity.

artículo científico publicado en 2016

Role of coagulation-associated processes on factor VIII immunogenicity in a mouse model of severe hemophilia A.

artículo científico publicado en 2014

Role of natural antibodies in immune homeostasis: IVIg perspective.

artículo científico publicado en 2008

Role of the intrinsic coagulation pathway in atherogenesis assessed in hemophilic apolipoprotein E knockout mice

artículo científico publicado en 2005

Selective impairment of serum antibody repertoires toward muscle and thymus antigens in patients with seronegative and seropositive myasthenia gravis

scientific article published on 01 August 1998

Self-reactive antibodies (natural autoantibodies) in healthy individuals

scientific article published on 01 July 1998

Sialylation may be dispensable for reciprocal modulation of helper T cells by intravenous immunoglobulin.

artículo científico publicado en 2014

Splenic marginal zone antigen-presenting cells are critical for the primary allo-immune response to therapeutic factor VIII in hemophilia A.

artículo científico publicado en 2009

Stability of natural self-reactive antibody repertoires during aging

scientific article published on 01 January 1999

Standardizing terms, definitions and concepts for describing and interpreting unwanted immunogenicity of biopharmaceuticals: recommendations of the Innovative Medicines Initiative ABIRISK consortium

artículo científico publicado en 2015

Summary report of the First International Conference on inhibitors in haemophilia A.

artículo científico publicado en 2016

Surveillance of antigen-presenting cells by CD4+ CD25+ regulatory T cells in autoimmunity: immunopathogenesis and therapeutic implications.

artículo científico publicado en 2009

T cell-derived IL-22 amplifies IL-1β-driven inflammation in human adipose tissue: relevance to obesity and type 2 diabetes.

artículo científico publicado en 2014

The ADAMTS131239-1253 peptide is a dominant HLA-DR1-restricted CD4+ T-cell epitope

artículo científico publicado en 2017

The C1 and C2 domains of blood coagulation factor VIII mediate its endocytosis by dendritic cells.

scientific article published on 06 October 2016

The antiinflammatory IgG.

artículo científico publicado en 2008

The interaction between factor H and VWF increases factor H cofactor activity and regulates VWF prothrombotic status

artículo científico publicado en 2013

The prevalence of proteolytic antibodies against factor VIII in hemophilia A.

artículo científico publicado en 2002

The role of VWF in the immunogenicity of FVIII.

scientific article published on January 2008

The self-reactive antibody repertoire of normal human serum IgM is acquired in early childhood and remains conserved throughout life

artículo científico publicado en 1996

Therapeutic factor VIII does not trigger TLR1.2 and TLR2.6 signalling in vitro.

artículo científico publicado en 2012

Thermodynamic analysis of the interaction of factor VIII with von Willebrand factor.

artículo científico publicado en 2012

Thermodynamic stability contributes to immunoglobulin specificity

artículo científico publicado en 2014

Transition towards antigen-binding promiscuity of a monospecific antibody

artículo científico publicado en 2006

Use of intravenous polyclonal immunoglobulins in autoimmune and inflammatory disorders

artículo científico publicado en 2007

VWF protects FVIII from endocytosis by dendritic cells and subsequent presentation to immune effectors.

artículo científico publicado en 2006

Varied immune response to FVIII: presence of proteolytic antibodies directed to factor VIII in different human pathologies

artículo científico publicado en 2009

[Immunomodulatory effects of intravenous immunoglobulins in autoimmune diseases]

artículo científico publicado en 1999

[Regulation of autoreactivity by the idiotypic network and therapeutic modulation of autoimmunity by polyvalent intravenous immunoglobulins (IgIV)]

scientific article published on 01 May 1996

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