Lista de obras - Juan Roa - Dominio Público Uruguay

A microRNA switch regulates the rise in hypothalamic GnRH production before puberty

artículo científico publicado en 2016

Advanced vaginal opening and precocious activation of the reproductive axis by KiSS-1 peptide, the endogenous ligand of GPR54.

artículo científico publicado en 2004

Alterations in hypothalamic KiSS-1 system in experimental diabetes: early changes and functional consequences.

artículo científico publicado en 2008

Changes in hypothalamic KiSS-1 system and restoration of pubertal activation of the reproductive axis by kisspeptin in undernutrition

artículo científico publicado en 2005

Changes in keratin 8/18 expression in human granulosa cell lineage are associated to cell death/survival events: potential implications for the maintenance of the ovarian reserve.

artículo científico publicado en 2018

Characterization of the Potent Luteinizing Hormone-Releasing Activity of KiSS-1 Peptide, the Natural Ligand of GPR54

artículo científico publicado en 2004

Connecting metabolism and gonadal function: Novel central neuropeptide pathways involved in the metabolic control of puberty and fertility

artículo científico publicado en 2017

Connecting metabolism and reproduction: roles of central energy sensors and key molecular mediators

artículo científico

Crowding and Follicular Fate: Spatial Determinants of Follicular Reserve and Activation of Follicular Growth in the Mammalian Ovary

artículo científico publicado en 2015

Defining a novel leptin-melanocortin-kisspeptin pathway involved in the metabolic control of puberty

artículo científico publicado en 2016

Dependence of fertility on kisspeptin-Gpr54 signaling at the GnRH neuron

artículo científico publicado en 2013

Desensitization of gonadotropin responses to kisspeptin in the female rat: analyses of LH and FSH secretion at different developmental and metabolic states.

artículo científico publicado en 2008

Development and validation of a method for precise dating of female puberty in laboratory rodents: The puberty ovarian maturation score (Pub-Score).

artículo científico publicado en 2017

Developmental and hormonally regulated messenger ribonucleic acid expression of KiSS-1 and its putative receptor, GPR54, in rat hypothalamus and potent luteinizing hormone-releasing activity of KiSS-1 peptide.

artículo científico publicado en 2004

Differential modulation of gonadotropin responses to kisspeptin by aminoacidergic, peptidergic, and nitric oxide neurotransmission

artículo científico publicado en 2012

Direct Actions of Kisspeptins on GnRH Neurons Permit Attainment of Fertility but are Insufficient to Fully Preserve Gonadotropic Axis Activity.

artículo científico publicado en 2016

Direct Regulation of GnRH Neuron Excitability by Arcuate Nucleus POMC and NPY Neuron Neuropeptides in Female Mice ⬇️

artículo científico publicado el 4 de septiembre de 2012

Direct stimulatory effect of ghrelin on pituitary release of LH through a nitric oxide-dependent mechanism that is modulated by estrogen

artículo científico publicado en 2007

Effects and interactions of tachykinins and dynorphin on FSH and LH secretion in developing and adult rats

artículo científico publicado en 2014

Effects of KiSS-1 peptide, the natural ligand of GPR54, on follicle-stimulating hormone secretion in the rat.

artículo científico publicado en 2005

Effects of galanin-like peptide on luteinizing hormone secretion in the rat: sexually dimorphic responses and enhanced sensitivity at male puberty

artículo científico publicado en 2006

Effects of single or repeated intravenous administration of kisspeptin upon dynamic LH secretion in conscious male rats

artículo científico publicado en 2006

Energy balance and puberty onset: emerging role of central mTOR signaling

scientific article published on 16 June 2010

Expression of KiSS-1 in rat ovary: putative local regulator of ovulation?

artículo científico publicado en 2006

Expression of KiSS-1 in rat oviduct: possible involvement in prevention of ectopic implantation?

scientific journal article

Expression of hypothalamic KiSS-1 system and rescue of defective gonadotropic responses by kisspeptin in streptozotocin-induced diabetic male rats

artículo científico publicado en 2006

Follicle-stimulating hormone responses to kisspeptin in the female rat at the preovulatory period: modulation by estrogen and progesterone receptors

artículo científico publicado en 2008

Ghrelin inhibits the proliferative activity of immature Leydig cells in vivo and regulates stem cell factor messenger ribonucleic acid expression in rat testis.

artículo científico publicado en 2004

Gonadal hormone-dependent vs. -independent effects of kisspeptin signaling in the control of body weight and metabolic homeostasis

artículo científico publicado en 2019

Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance.

artículo científico publicado en 2017

Hypothalamic expression of KiSS-1 system and gonadotropin-releasing effects of kisspeptin in different reproductive states of the female Rat.

artículo científico publicado en 2006

Hypothalamic mTOR pathway mediates thyroid hormone-induced hyperphagia in hyperthyroidism.

artículo científico publicado en 2012

In vivo and in vitro structure-activity relationships and structural conformation of Kisspeptin-10-related peptides

artículo científico publicado en 2009

Intergenerational Influence of Paternal Obesity on Metabolic and Reproductive Health Parameters of the Offspring: Male-Preferential Impact and Involvement of Kiss1-Mediated Pathways

artículo científico publicado en 2017

KiSS-1 in the mammalian ovary: distribution of kisspeptin in human and marmoset and alterations in KiSS-1 mRNA levels in a rat model of ovulatory dysfunction.

artículo científico publicado en 2009

KiSS-1 system and reproduction: comparative aspects and roles in the control of female gonadotropic axis in mammals

artículo científico publicado en 2007

KiSS-1/kisspeptins and the metabolic control of reproduction: physiologic roles and putative physiopathological implications

scientific article published on 21 June 2008

Kisspeptins and the control of gonadotropin secretion in male and female rodents.

artículo científico publicado en 2008

Kisspeptins in reproductive biology: consensus knowledge and recent developments

artículo científico publicado en 2011

Leptin deficiency and diet-induced obesity reduce hypothalamic kisspeptin expression in mice

artículo científico publicado en 2011

Maternal serum ghrelin levels in early IVF pregnancies: lack of prognostic value for viable pregnancy and altered post-prandial responses

artículo científico publicado en 2008

Metabolic and Gonadotropic Impact of Sequential Obesogenic Insults in the Female: Influence of the Loss of Ovarian Secretion.

artículo científico publicado en 2015

Metabolic control of puberty onset: new players, new mechanisms

artículo científico publicado en 2009

Metabolic regulation of female puberty via hypothalamic AMPK-kisspeptin signaling

article published in the Proceedings of the National Academy of Sciences of the United States of America

Neuromedin s as novel putative regulator of luteinizing hormone secretion.

artículo científico publicado en 2006

New frontiers in kisspeptin/GPR54 physiology as fundamental gatekeepers of reproductive function

artículo científico publicado en 2007

Novel expression and functional role of ghrelin in chicken ovary

Novel role of the anorexigenic peptide neuromedin U in the control of LH secretion and its regulation by gonadal hormones and photoperiod

artículo científico publicado en 2007

Opposite roles of estrogen receptor (ER)-alpha and ERbeta in the modulation of luteinizing hormone responses to kisspeptin in the female rat: implications for the generation of the preovulatory surge.

artículo científico publicado en 2008

Persistent impairment of hypothalamic KiSS-1 system after exposures to estrogenic compounds at critical periods of brain sex differentiation.

artículo científico publicado en 2008

Physiological roles of gonadotropin-inhibitory hormone signaling in the control of mammalian reproductive axis: studies in the NPFF1 receptor null mouse

artículo científico publicado en 2014

Role of GnRH Neurons and Their Neuronal Afferents as Key Integrators between Food Intake Regulatory Signals and the Control of Reproduction

artículo científico publicado en 2013

SF1-Specific AMPKα1 Deletion Protects Against Diet-Induced Obesity

scientific article published on 13 August 2018

SIRT1 mediates obesity- and nutrient-dependent perturbation of pubertal timing by epigenetically controlling Kiss1 expression

scientific article published in Nature Communications

Selective role of neuropeptide Y receptor subtype Y2 in the control of gonadotropin secretion in the rat.

artículo científico publicado en 2007

Serotonin acts through 5-HT1 and 5-HT2 receptors to exert biphasic actions on GnRH neuron excitability in the mouse

artículo científico publicado en 2013

Sex-Biased Physiological Roles of NPFF1R, the Canonical Receptor of RFRP-3, in Food Intake and Metabolic Homeostasis Revealed by its Congenital Ablation in mice

scholarly article by Silvia Leon et al published October 2018 in Metabolism

Sexual differentiation of Kiss1 gene expression in the brain of the rat.

artículo científico publicado en 2007

Stimulatory effect of PYY-(3-36) on gonadotropin secretion is potentiated in fasted rats

artículo científico publicado en 2006

The Fusarium oxysporum sti35 gene functions in thiamine biosynthesis and oxidative stress response

artículo científico publicado en 2007

The anorexigenic neuropeptide, nesfatin-1, is indispensable for normal puberty onset in the female rat.

artículo científico

The mammalian target of rapamycin as novel central regulator of puberty onset via modulation of hypothalamic Kiss1 system.

artículo científico publicado en 2009

Unique Features of a Unique Cell: The Wonder World of GnRH Neurons

artículo científico publicado en 2018

Lista de obras de Juan Roa

A microRNA switch regulates the rise in hypothalamic GnRH production before puberty

Advanced vaginal opening and precocious activation of the reproductive axis by KiSS-1 peptide, the endogenous ligand of GPR54.

Alterations in hypothalamic KiSS-1 system in experimental diabetes: early changes and functional consequences.

Changes in hypothalamic KiSS-1 system and restoration of pubertal activation of the reproductive axis by kisspeptin in undernutrition

Changes in keratin 8/18 expression in human granulosa cell lineage are associated to cell death/survival events: potential implications for the maintenance of the ovarian reserve.

Characterization of the Potent Luteinizing Hormone-Releasing Activity of KiSS-1 Peptide, the Natural Ligand of GPR54

Connecting metabolism and gonadal function: Novel central neuropeptide pathways involved in the metabolic control of puberty and fertility

Connecting metabolism and reproduction: roles of central energy sensors and key molecular mediators

Crowding and Follicular Fate: Spatial Determinants of Follicular Reserve and Activation of Follicular Growth in the Mammalian Ovary

Defining a novel leptin-melanocortin-kisspeptin pathway involved in the metabolic control of puberty

Dependence of fertility on kisspeptin-Gpr54 signaling at the GnRH neuron

Desensitization of gonadotropin responses to kisspeptin in the female rat: analyses of LH and FSH secretion at different developmental and metabolic states.

Development and validation of a method for precise dating of female puberty in laboratory rodents: The puberty ovarian maturation score (Pub-Score).

Developmental and hormonally regulated messenger ribonucleic acid expression of KiSS-1 and its putative receptor, GPR54, in rat hypothalamus and potent luteinizing hormone-releasing activity of KiSS-1 peptide.

Differential modulation of gonadotropin responses to kisspeptin by aminoacidergic, peptidergic, and nitric oxide neurotransmission

Direct Actions of Kisspeptins on GnRH Neurons Permit Attainment of Fertility but are Insufficient to Fully Preserve Gonadotropic Axis Activity.

Direct Regulation of GnRH Neuron Excitability by Arcuate Nucleus POMC and NPY Neuron Neuropeptides in Female Mice ⬇️

Direct stimulatory effect of ghrelin on pituitary release of LH through a nitric oxide-dependent mechanism that is modulated by estrogen

Effects and interactions of tachykinins and dynorphin on FSH and LH secretion in developing and adult rats

Effects of KiSS-1 peptide, the natural ligand of GPR54, on follicle-stimulating hormone secretion in the rat.

Effects of galanin-like peptide on luteinizing hormone secretion in the rat: sexually dimorphic responses and enhanced sensitivity at male puberty

Effects of single or repeated intravenous administration of kisspeptin upon dynamic LH secretion in conscious male rats

Energy balance and puberty onset: emerging role of central mTOR signaling

Expression of KiSS-1 in rat ovary: putative local regulator of ovulation?

Expression of KiSS-1 in rat oviduct: possible involvement in prevention of ectopic implantation?

Expression of hypothalamic KiSS-1 system and rescue of defective gonadotropic responses by kisspeptin in streptozotocin-induced diabetic male rats

Follicle-stimulating hormone responses to kisspeptin in the female rat at the preovulatory period: modulation by estrogen and progesterone receptors

Ghrelin inhibits the proliferative activity of immature Leydig cells in vivo and regulates stem cell factor messenger ribonucleic acid expression in rat testis.

Gonadal hormone-dependent vs. -independent effects of kisspeptin signaling in the control of body weight and metabolic homeostasis

Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance.

Hypothalamic expression of KiSS-1 system and gonadotropin-releasing effects of kisspeptin in different reproductive states of the female Rat.

Hypothalamic mTOR pathway mediates thyroid hormone-induced hyperphagia in hyperthyroidism.

In vivo and in vitro structure-activity relationships and structural conformation of Kisspeptin-10-related peptides

Intergenerational Influence of Paternal Obesity on Metabolic and Reproductive Health Parameters of the Offspring: Male-Preferential Impact and Involvement of Kiss1-Mediated Pathways

KiSS-1 in the mammalian ovary: distribution of kisspeptin in human and marmoset and alterations in KiSS-1 mRNA levels in a rat model of ovulatory dysfunction.

KiSS-1 system and reproduction: comparative aspects and roles in the control of female gonadotropic axis in mammals

KiSS-1/kisspeptins and the metabolic control of reproduction: physiologic roles and putative physiopathological implications

Kisspeptins and the control of gonadotropin secretion in male and female rodents.

Kisspeptins in reproductive biology: consensus knowledge and recent developments

Leptin deficiency and diet-induced obesity reduce hypothalamic kisspeptin expression in mice

Maternal serum ghrelin levels in early IVF pregnancies: lack of prognostic value for viable pregnancy and altered post-prandial responses

Metabolic and Gonadotropic Impact of Sequential Obesogenic Insults in the Female: Influence of the Loss of Ovarian Secretion.

Metabolic control of puberty onset: new players, new mechanisms

Metabolic regulation of female puberty via hypothalamic AMPK-kisspeptin signaling

Neuromedin s as novel putative regulator of luteinizing hormone secretion.

New frontiers in kisspeptin/GPR54 physiology as fundamental gatekeepers of reproductive function

Novel expression and functional role of ghrelin in chicken ovary

Novel role of the anorexigenic peptide neuromedin U in the control of LH secretion and its regulation by gonadal hormones and photoperiod

Opposite roles of estrogen receptor (ER)-alpha and ERbeta in the modulation of luteinizing hormone responses to kisspeptin in the female rat: implications for the generation of the preovulatory surge.

Persistent impairment of hypothalamic KiSS-1 system after exposures to estrogenic compounds at critical periods of brain sex differentiation.

Physiological roles of gonadotropin-inhibitory hormone signaling in the control of mammalian reproductive axis: studies in the NPFF1 receptor null mouse

Role of GnRH Neurons and Their Neuronal Afferents as Key Integrators between Food Intake Regulatory Signals and the Control of Reproduction

SF1-Specific AMPKα1 Deletion Protects Against Diet-Induced Obesity

SIRT1 mediates obesity- and nutrient-dependent perturbation of pubertal timing by epigenetically controlling Kiss1 expression

Selective role of neuropeptide Y receptor subtype Y2 in the control of gonadotropin secretion in the rat.

Serotonin acts through 5-HT1 and 5-HT2 receptors to exert biphasic actions on GnRH neuron excitability in the mouse

Sex-Biased Physiological Roles of NPFF1R, the Canonical Receptor of RFRP-3, in Food Intake and Metabolic Homeostasis Revealed by its Congenital Ablation in mice

Sexual differentiation of Kiss1 gene expression in the brain of the rat.

Stimulatory effect of PYY-(3-36) on gonadotropin secretion is potentiated in fasted rats

The Fusarium oxysporum sti35 gene functions in thiamine biosynthesis and oxidative stress response

The anorexigenic neuropeptide, nesfatin-1, is indispensable for normal puberty onset in the female rat.

The mammalian target of rapamycin as novel central regulator of puberty onset via modulation of hypothalamic Kiss1 system.

Unique Features of a Unique Cell: The Wonder World of GnRH Neurons