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Lista de obras de Martin J Holland

A chlamydial type III-secreted effector protein (Tarp) is predominantly recognized by antibodies from humans infected with Chlamydia trachomatis and induces protective immunity against upper genital tract pathologies in mice

artículo científico publicado en 2009

A coding polymorphism in matrix metalloproteinase 9 reduces risk of scarring sequelae of ocular Chlamydia trachomatis infection.

artículo científico publicado en 2006

A diagnostics platform for the integrated mapping, monitoring, and surveillance of neglected tropical diseases: rationale and target product profiles

artículo científico publicado en 2012

Active Trachoma Cases in the Solomon Islands Have Varied Polymicrobial Community Structures but Do Not Associate with Individual Non-Chlamydial Pathogens of the Eye.

artículo científico publicado en 2017

Active trachoma and ocular Chlamydia trachomatis infection in two Gambian regions: on course for elimination by 2020?

artículo científico publicado en 2009

Active trachoma is associated with increased conjunctival expression of IL17A and profibrotic cytokines

artículo científico publicado en 2011

An index of community ocular Chlamydia trachomatis load for control of trachoma.

artículo científico publicado en 2005

An outbreak of acute haemorrhagic conjunctivitis associated with coxsackievirus A24 variant in The Gambia, West Africa

artículo científico publicado en 2017

Analysis of flow cytometry data using an automatic processing tool

artículo científico publicado en 2008

Anthropometric indices of Gambian children after one or three annual rounds of mass drug administration with azithromycin for trachoma control

artículo científico publicado en 2014

Antibody response to the 60-kDa chlamydial heat-shock protein is associated with scarring trachoma.

artículo científico publicado en 1998

Association between intestinal bacterial carriage, biomarkers of environmental enteric dysfunction, and stunting in rural Malawian children

artículo científico publicado en 2022

Association between ocular bacterial carriage and follicular trachoma following mass azithromycin distribution in The Gambia

artículo científico publicado en 2013

Biogeography of the ecosystems of the healthy human body

artículo científico publicado en 2013

Blinding Trachoma: Systematic Review of Rates and Risk Factors for Progressive Disease

artículo científico publicado en 2016

Can corneal pannus with trachomatous inflammation--follicular be used in combination as an improved specific clinical sign for current ocular Chlamydia trachomatis infection?

artículo científico publicado en 2016

Chlamydia trachomatis ompA variants in trachoma: what do they tell us?

artículo científico publicado en 2008

Chlamydial positivity of nasal discharge at baseline is associated with ocular chlamydial positivity 2 months following azithromycin treatment.

artículo científico publicado en 2006

Co-evolution of genomes and plasmids within Chlamydia trachomatis and the emergence in Sweden of a new variant strain

artículo científico publicado en 2009

Conjunctival FOXP3 expression in trachoma: do regulatory T cells have a role in human ocular Chlamydia trachomatis infection?

artículo científico publicado en 2006

Conjunctival MicroRNA expression in inflammatory trachomatous scarring

artículo científico publicado en 2013

Conjunctival Microbiome-Host Responses Are Associated With Impaired Epithelial Cell Health in Both Early and Late Stages of Trachoma

scientific article published on 21 August 2019

Conjunctival chlamydial 16S ribosomal RNA expression in trachoma: is chlamydial metabolic activity required for disease to develop?

artículo científico publicado en 2006

Conjunctival expression of matrix metalloproteinase and proinflammatory cytokine genes after trichiasis surgery

artículo científico publicado en 2010

Conjunctival fibrosis and the innate barriers to Chlamydia trachomatis intracellular infection: a genome wide association study

artículo científico publicado en 2015

Conjunctival scarring in trachoma is associated with the HLA-C ligand of KIR and is exacerbated by heterozygosity at KIR2DL2/KIR2DL3.

artículo científico publicado en 2014

Conjunctival transcriptome in scarring trachoma

artículo científico publicado en 2010

Conjunctival transcriptome profiling of Solomon Islanders with active trachoma in the absence of Chlamydia trachomatis infection.

artículo científico publicado en 2018

Correction: Mass Treatment with Azithromycin for Trachoma: When Is One Round Enough? Results from the PRET Trial in The Gambia.

artículo científico publicado en 2013

Correction: Post-Operative Recurrent Trachomatous Trichiasis Is Associated with Increased Conjunctival Expression of S100A7 (Psoriasin)

Costs of testing for ocular Chlamydia trachomatis infection compared to mass drug administration for trachoma in the Gambia: application of results from the PRET study

artículo científico publicado en 2015

Cytokine and fibrogenic gene expression in the conjunctivas of subjects from a Gambian community where trachoma is endemic

artículo científico publicado en 2004

Defining Seropositivity Thresholds for Use in Trachoma Elimination Studies.

artículo científico publicado en 2017

Design and baseline data of a randomized trial to evaluate coverage and frequency of mass treatment with azithromycin: the Partnership for Rapid Elimination of Trachoma (PRET) in Tanzania and The Gambia

artículo científico publicado en 2011

Development and evaluation of a next-generation digital PCR diagnostic assay for ocular Chlamydia trachomatis infections

artículo científico publicado en 2013

Diagnostic accuracy of a prototype point-of-care test for ocular Chlamydia trachomatis under field conditions in The Gambia and Senegal

artículo científico publicado en 2011

Differential frequency of NKG2C/KLRC2 deletion in distinct African populations and susceptibility to Trachoma: a new method for imputation of KLRC2 genotypes from SNP genotyping data

artículo científico publicado en 2016

DjinniChip: evaluation of a novel molecular rapid diagnostic device for the detection of Chlamydia trachomatis in trachoma-endemic areas

artículo científico publicado en 2020

Early interleukin-4: its role in the switch towards a Th2 response and IgE-mediated allergy

artículo científico publicado en 1999

Effect of azithromycin mass drug administration for trachoma on spleen rates in Gambian children

artículo científico publicado en 2014

Estimating household and community transmission of ocular Chlamydia trachomatis

artículo científico publicado en 2009

Evaluation of a Chlamydia trachomatis-specific, commercial, real-time PCR for use with ocular swabs

artículo científico publicado en 2018

Eyescores: an open platform for secure electronic data and photographic evidence collection in ophthalmological field studies

artículo científico publicado en 2012

FOXP3 gene expression in a tuberculosis case contact study

artículo científico publicado en 2007

Genetic variation at the TNF locus and the risk of severe sequelae of ocular Chlamydia trachomatis infection in Gambians.

artículo científico publicado en 2007

Genome-wide identification of Chlamydia trachomatis antigens associated with trachomatous trichiasis

artículo científico publicado en 2012

Genome-wide profiling of humoral immunity and pathogen genes under selection identifies immune evasion tactics of Chlamydia trachomatis during ocular infection

artículo científico

Haptoglobin and sickle cell polymorphisms and risk of active trachoma in Gambian children

artículo científico publicado en 2010

Human conjunctival transcriptome analysis reveals the prominence of innate defense in Chlamydia trachomatis infection

artículo científico publicado en 2010

Immunofibrogenic Gene Expression Patterns in Tanzanian Children with Ocular Chlamydia trachomatis Infection, Active Trachoma and Scarring: Baseline Results of a 4-Year Longitudinal Study

artículo científico publicado en 2017

Immunohistochemical Analysis of Scarring Trachoma Indicates Infiltration by Natural Killer and Undefined CD45 Negative Cells

artículo científico publicado en 2016

Immunopathogenesis of Progressive Scarring Trachoma: Results of a 4-Year Longitudinal Study in Tanzanian Children

scientific article published on 23 March 2020

Impact of a single round of mass drug administration with azithromycin on active trachoma and ocular Chlamydia trachomatis prevalence and circulating strains in The Gambia and Senegal

artículo científico publicado en 2019

In vivo confocal microscopy and histopathology of the conjunctiva in trachomatous scarring and normal tissue: a systematic comparison

artículo científico publicado en 2013

Increased Epithelial Expression of CTGF and S100A7 with Elevated Subepithelial Expression of IL-1β in Trachomatous Trichiasis

artículo científico publicado en 2016

Infection with Chlamydia trachomatis after mass treatment of a trachoma hyperendemic community in Tanzania: a longitudinal study

artículo científico publicado en 2005

Influenza Vaccination Primes Human Myeloid Cell Cytokine Secretion and NK Cell Function

scientific article published on 19 August 2019

Innate immune responses and modified extracellular matrix regulation characterize bacterial infection and cellular/connective tissue changes in scarring trachoma.

artículo científico publicado en 2011

Innate immunity in ocular Chlamydia trachomatis infection: contribution of IL8 and CSF2 gene variants to risk of trachomatous scarring in Gambians

artículo científico publicado en 2009

Intramuscular Immunisation with Chlamydial Proteins Induces Chlamydia trachomatis Specific Ocular Antibodies

artículo científico publicado en 2015

Inverse relationship between microRNA-155 and -184 expression with increasing conjunctival inflammation during ocular Chlamydia trachomatis infection

artículo científico publicado en 2016

Jaagsiekte retrovirus establishes a disseminated infection of the lymphoid tissues of sheep affected by pulmonary adenomatosis

artículo científico publicado en 1996

Killer-cell Immunoglobulin-like Receptor gene linkage and copy number variation analysis by droplet digital PCR

artículo científico publicado en 2014

Mass administration of azithromycin and Streptococcus pneumoniae carriage: cross-sectional surveys in the Gambia

artículo científico publicado en 2014

Mass treatment and the effect on the load of Chlamydia trachomatis infection in a trachoma-hyperendemic community.

artículo científico publicado en 2005

Mass treatment with azithromycin for trachoma: when is one round enough? Results from the PRET Trial in the Gambia

artículo científico publicado en 2013

Mass treatment with single-dose azithromycin for trachoma.

artículo científico publicado en 2004

Mycobacterium leprae Activates Toll-Like Receptor-4 Signaling and Expression on Macrophages Depending on Previous Bacillus Calmette-Guerin Vaccination

artículo científico publicado en 2016

Non-participation during azithromycin mass treatment for trachoma in The Gambia: heterogeneity and risk factors

artículo científico publicado en 2014

Ocular chlamydial genomic variants and disease severity in trachoma: a cross-sectional population-based genome-wide association study

scientific article published in The Lancet

Ocular immune responses, Chlamydia trachomatis infection and clinical signs of trachoma before and after azithromycin mass drug administration in a treatment naïve trachoma-endemic Tanzanian community

artículo científico publicado en 2019

Parasite immunity: Pathways for expelling intestinal helminths

artículo científico publicado en 1998

Pathogenesis of progressive scarring trachoma in Ethiopia and Tanzania and its implications for disease control: two cohort studies

artículo científico publicado en 2015

Pathogenic diversity among Chlamydia trachomatis ocular strains in nonhuman primates is affected by subtle genomic variations

artículo científico publicado en 2008

Pathway-Wide Genetic Risks in Chlamydial Infections Overlap between Tissue Tropisms: A Genome-Wide Association Scan.

artículo científico publicado en 2018

Pathway-focused arrays reveal increased matrix metalloproteinase-7 (matrilysin) transcription in trachomatous trichiasis.

artículo científico publicado en 2010

Pathways-wide genetic risks in Chlamydial infections overlap between tissue tropisms: A genome-wide association scan

Persistence of Innate Immune Pathways in Late Stage Human Bacterial and Fungal Keratitis: Results from a Comparative Transcriptome Analysis

artículo científico publicado en 2017

Phylogenetic analysis of Chlamydia trachomatis Tarp and correlation with clinical phenotype

artículo científico publicado en 2010

Plasmid copy number and disease severity in naturally occurring ocular Chlamydia trachomatis infection

artículo científico publicado en 2013

Plasmodium falciparum infection of the placenta affects newborn immune responses

artículo científico publicado en 2003

Population-based analysis of ocular Chlamydia trachomatis in trachoma-endemic West African communities identifies genomic markers of disease severity

Population-based analysis of ocular Chlamydia trachomatis in trachoma-endemic West African communities identifies genomic markers of disease severity.

artículo científico publicado en 2018

Population-based prevalence survey of follicular trachoma and trachomatous trichiasis in the Casamance region of Senegal

artículo científico publicado en 2017

Post-operative recurrent trachomatous trichiasis is associated with increased conjunctival expression of S100A7 (psoriasin).

artículo científico publicado en 2012

Profiling and validation of individual and patterns of Chlamydia trachomatis-specific antibody responses in trachomatous trichiasis

artículo científico publicado en 2017

Profound and sustained reduction in Chlamydia trachomatis in The Gambia: a five-year longitudinal study of trachoma endemic communities

artículo científico publicado en 2010

Progression of scarring trachoma in Tanzanian children: A four-year cohort study

scientific article published on 14 August 2019

Proteins secreted by the parasitic nematode Nippostrongylus brasiliensis act as adjuvants for Th2 responses

artículo científico publicado en 2000

Re-emergence of Chlamydia trachomatis infection after mass antibiotic treatment of a trachoma-endemic Gambian community: a longitudinal study

artículo científico publicado en 2005

Reduced-cost Chlamydia trachomatis-specific multiplex real-time PCR diagnostic assay evaluated for ocular swabs and use by trachoma research programmes.

scientific article published on 06 May 2017

Revealing the history of sheep domestication using retrovirus integrations

artículo científico publicado en 2009

Risk factors for active trachoma and ocular Chlamydia trachomatis infection in treatment-naïve trachoma-hyperendemic communities of the Bijagós Archipelago, Guinea Bissau

artículo científico publicado en 2014

Risk factors for active trachoma in The Gambia.

artículo científico publicado en 2008

Risk of trachomatous scarring and trichiasis in Gambians varies with SNP haplotypes at the interferon-gamma and interleukin-10 loci.

artículo científico publicado en 2005

Selective maturation of dendritic cells byNippostrongylus brasiliensis-secreted proteins drives Th2 immune responses

article

Serology for trachoma surveillance after cessation of mass drug administration

artículo científico publicado en 2015

Short-term increase in prevalence of nasopharyngeal carriage of macrolide-resistant Staphylococcus aureus following mass drug administration with azithromycin for trachoma control

artículo científico publicado en 2017

Spatial clustering of high load ocular Chlamydia trachomatis infection in trachoma: a cross-sectional population-based study

artículo científico publicado en 2017

Strategies for control of trachoma: observational study with quantitative PCR.

scientific article published on July 2003

Susceptibility to sequelae of human ocular chlamydial infection associated with allelic variation in IL10 cis-regulation

artículo científico publicado en 2007

Synthetic peptides based on Chlamydia trachomatis antigens identify cytotoxic T lymphocyte responses in subjects from a trachoma-endemic population.

scientific article published on January 1997

Systemic effector and regulatory immune responses to chlamydial antigens in trachomatous trichiasis

artículo científico publicado en 2011

T helper type-1 (Th1)/Th2 profiles of peripheral blood mononuclear cells (PBMC); responses to antigens of Chlamydia trachomatis in subjects with severe trachomatous scarring.

artículo científico publicado en 1996

Temporal cytokine gene expression patterns in subjects with trachoma identify distinct conjunctival responses associated with infection.

artículo científico publicado en 2005

Th2 induction by Nippostrongylus secreted antigens in mice deficient in B cells, eosinophils or MHC Class I-related receptors

artículo científico publicado en 2005

The Relationship between Active Trachoma and Ocular Chlamydia trachomatis Infection before and after Mass Antibiotic Treatment

artículo científico publicado en 2016

The conjunctival microbiome in health and trachomatous disease: a case control study

artículo científico publicado en 2014

The development of an age-structured model for trachoma transmission dynamics, pathogenesis and control

artículo científico publicado en 2009

The frequency of Chlamydia trachomatis major outer membrane protein-specific CD8+ T lymphocytes in active trachoma is associated with current ocular infection.

artículo científico publicado en 2006

The impact of a single round of community mass treatment with azithromycin on disease severity and ocular Chlamydia trachomatis load in treatment-naïve trachoma-endemic island communities in West Africa

artículo científico publicado en 2017

Towards a safe and effective chlamydial vaccine: lessons from the eye

artículo científico publicado en 2014

Trachoma and Ocular Chlamydial Infection in the Era of Genomics

artículo científico publicado en 2015

Trachoma prevalence and associated risk factors in the gambia and Tanzania: baseline results of a cluster randomised controlled trial

artículo científico publicado en 2010

Trachoma: protective and pathogenic ocular immune responses to Chlamydia trachomatis

artículo científico publicado en 2013

Trichiasis surgery in The Gambia: a 4-year prospective study

artículo científico publicado en 2010

Two doses of azithromycin to eliminate trachoma in a Tanzanian community.

artículo científico publicado en 2008

Viability PCR shows that non-ocular surfaces could contribute to transmission of Chlamydia trachomatis infection in trachoma

scientific article published on 15 July 2020

When can antibiotic treatments for trachoma be discontinued? Graduating communities in three African countries

artículo científico publicado en 2009

Which members of a community need antibiotics to control trachoma? Conjunctival Chlamydia trachomatis infection load in Gambian villages

scientific article published on October 2003

Whole-genome analysis of diverse Chlamydia trachomatis strains identifies phylogenetic relationships masked by current clinical typing

artículo científico publicado en 2012

Whole-genome enrichment and sequencing of Chlamydia trachomatis directly from clinical samples

artículo científico publicado en 2014

Whole-genome sequencing of ocular Chlamydia trachomatis isolates from Gadarif State, Sudan

artículo científico publicado en 2019

Will droplet digital PCR become the test of choice for detecting and quantifying ocular Chlamydia trachomatis infection? Maybe

artículo científico publicado en 2014

miRNAs that associate with conjunctival inflammation and ocular Chlamydia trachomatis infection do not predict progressive disease

artículo científico publicado en 2017

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