Lista de obras - Stephen Wheatcroft - Dominio Público Uruguay

173 Insulin-like growth factor binding protein 2 (igfbp2): a positive regulator of angiogenesis?

232 Endothelial ship2 knockout causes nox2 nadph oxidase-dependent oxidative stress and endothelial dysfunction

26 Effect of Age and Gender on Outcomes Following Primary Percutaneous Coronary Intervention for ST-elevation Myocardial Infarction in a UK Tertiary Centre

33 Influence of ethnicity on outcomes in primary percutaneous coronary intervention for ST-elevation myocardial infarction

A heat-shock protein axis regulates VEGFR2 proteolysis, blood vessel development and repair

artículo científico publicado en 2012

Accelerated endothelial dysfunction in mild prediabetic insulin resistance: the early role of reactive oxygen species.

artículo científico publicado en 2007

Acute and one year clinical outcomes following implantation of bioresorbable vascular scaffolds: the ABSORB UK Registry

artículo científico publicado en 2017

Ankle pressures in UK South Asians with diabetes mellitus: a case control study

artículo científico publicado en 2013

Assessing Coronary Blood Flow Physiology in the Cardiac Catheterisation Laboratory ⬇️

artículo científico publicado en 2017

Association of diabetes with increased all-cause mortality following primary percutaneous coronary intervention for ST-segment elevation myocardial infarction in the contemporary era.

artículo científico publicado en 2011

Asymmetric dimethylarginine and reduced nitric oxide bioavailability in young Black African men.

artículo científico publicado en 2007

Bilateral endophthalmitis and ARDS complicating group G streptococcal endocarditis

artículo científico publicado en 2005

Bivalirudin in patients undergoing primary percutaneous coronary intervention for acute ST-elevation myocardial infarction: outcomes in a large real-world population.

artículo científico publicado en 2013

Cardiovascular risk in patients with small and medium abdominal aortic aneurysms, and no history of cardiovascular disease.

artículo científico publicado en 2014

Changing characteristics and mode of death associated with chronic heart failure caused by left ventricular systolic dysfunction: a study across therapeutic eras

artículo científico publicado en 2011

Clinical and Preclinical Use of LOX-1-Specific Antibodies in Diagnostics and Therapeutics

artículo científico

Clinical outcomes following primary percutaneous coronary intervention for ST-elevation myocardial infarction according to sex and race ⬇️

artículo científico publicado en 2017

Detection and Quantification of Vascular Endothelial Growth Factor Receptor Tyrosine Kinases in Primary Human Endothelial Cells.

artículo científico publicado en 2015

Diabetes mellitus and mortality after acute coronary syndrome as a first or recurrent cardiovascular event

artículo científico publicado en 2008

Diabetes mellitus is associated with adverse prognosis in chronic heart failure of ischaemic and non-ischaemic aetiology

artículo científico publicado en 2013

Direct ambulance admission to the cardiac catheterization laboratory significantly reduces door-to-balloon times in primary percutaneous coronary intervention.

artículo científico publicado en 2008

Diurnal variation in vascular and metabolic function in diet-induced obesity: divergence of insulin resistance and loss of clock rhythm

artículo científico publicado en 2013

Does routine pressure wire assessment influence management strategy at coronary angiography for diagnosis of chest pain?: the RIPCORD study

artículo científico

Effect of endothelium-specific insulin resistance on endothelial function in vivo

artículo científico publicado en 2008

Effects of insulin resistance on endothelial progenitor cells and vascular repair

artículo científico publicado en 2009

Endothelial IGF-1 Receptor Signalling in Diabetes and Insulin Resistance

artículo científico

Endothelial Insulin Receptor Restoration Rescues Vascular Function in Male Insulin Receptor Haploinsufficient Mice ⬇️

Endothelial function and weight loss in obese humans

artículo científico publicado en 2005

Endothelium-specific insulin resistance leads to accelerated atherosclerosis in areas with disturbed flow patterns: a role for reactive oxygen species

artículo científico publicado en 2013

Haploinsufficiency of the insulin-like growth factor-1 receptor enhances endothelial repair and favorably modifies angiogenic progenitor cell phenotype

artículo científico publicado en 2014

How We Measure Heart Rate: Does it Matter?

artículo científico publicado en 2016

Human exercise-induced circulating progenitor cell mobilization is nitric oxide-dependent and is blunted in South Asian men.

artículo científico publicado en 2010

Hyperglycaemia, in relation to sex, and mortality after acute coronary syndrome

artículo científico publicado en 2007

IGF-binding protein-2 protects against the development of obesity and insulin resistance

artículo científico publicado en 2007

IGF-dependent and IGF-independent actions of IGF-binding protein-1 and -2: implications for metabolic homeostasis

artículo científico publicado en 2009

IGFBP-1 in Cardiometabolic Pathophysiology-Insights From Loss-of-Function and Gain-of-Function Studies in Male Mice

artículo científico publicado en 2019

In silico design and biological evaluation of a dual specificity kinase inhibitor targeting cell cycle progression and angiogenesis ⬇️

artículo científico publicado en 2014

Increasing circulating IGFBP1 levels improves insulin sensitivity, promotes nitric oxide production, lowers blood pressure, and protects against atherosclerosis

artículo científico publicado en 2012

Inducible nitric oxide synthase has divergent effects on vascular and metabolic function in obesity

artículo científico publicado en 2005

Inhibition of plasmin-mediated TAFI activation may affect development but not progression of abdominal aortic aneurysms ⬇️

artículo científico publicado en 2017

Insulin resistance and endothelial cell dysfunction: studies in mammalian models

artículo científico publicado en 2007

Insulin resistance impairs circulating angiogenic progenitor cell function and delays endothelial regeneration ⬇️

artículo científico publicado en 2011

Insulin-Like Growth Factor Binding Protein 1 Could Improve Glucose Regulation and Insulin Sensitivity Through Its RGD Domain

artículo científico publicado en 2016

Insulinlike Growth Factor-Binding Protein-1 Improves Vascular Endothelial Repair in Male Mice in the Setting of Insulin Resistance ⬇️

artículo científico publicado en 2017

Inter-subject differences in constitutive expression levels of the clock gene in man.

artículo científico publicado en 2007

Life-threatening coronary artery spasm following sirolimus-eluting stent deployment

artículo científico publicado en 2006

Novel role of the IGF-1 receptor in endothelial function and repair: studies in endothelium-targeted IGF-1 receptor transgenic mice ⬇️

artículo científico publicado en 2012

Nox2 NADPH oxidase has a critical role in insulin resistance-related endothelial cell dysfunction

artículo científico publicado en 2013

OBTAIN: a study of the occurrence of bleeding and thrombosis during anti-platelet therapy in non-cardiac surgery.

artículo científico publicado en 2011

Opposing roles of p47phox in basal versus angiotensin II-stimulated alterations in vascular O2- production, vascular tone, and mitogen-activated protein kinase activation

artículo científico publicado en 2004

Oxidized LDL activates blood platelets through CD36/NOX2-mediated inhibition of the cGMP/protein kinase G signaling cascade ⬇️

artículo científico publicado en 2015

Piezo1 channels sense whole body physical activity to reset cardiovascular homeostasis and enhance performance ⬇️

artículo científico

Pregnenolone sulphate- and cholesterol-regulated TRPM3 channels coupled to vascular smooth muscle secretion and contraction

artículo científico publicado en 2010

Preservation of vascular endothelial repair in mice with diet-induced obesity

artículo científico publicado en 2018

Preserved glucoregulation but attenuation of the vascular actions of insulin in mice heterozygous for knockout of the insulin receptor

artículo científico publicado en 2004

Real-world outcome from ST elevation myocardial infarction in the very elderly before and after the introduction of a 24/7 primary percutaneous coronary intervention service.

artículo científico publicado en 2010

Reply to: "Zimarino M et al. The adequacy of myocardial revascularization in patients with multivessel coronary artery disease".

artículo científico publicado en 2013

Restoring Akt1 activity in outgrowth endothelial cells from South Asian men rescues vascular reparative potential ⬇️

artículo científico publicado en 2014

Scavenger receptor structure and function in health and disease ⬇️

artículo científico publicado en 2015

Scavenger receptors and their potential as therapeutic targets in the treatment of cardiovascular disease

artículo científico publicado en 2010

Selective Enhancement of Insulin Sensitivity in the Endothelium In Vivo Reveals a Novel Proatherosclerotic Signaling Loop ⬇️

artículo científico publicado en 2016

Strain-dependent variation in vascular responses to nitric oxide in the isolated murine heart

artículo científico publicado en 2002

TRPC5 ion channel permeation promotes weight gain in hypercholesterolaemic mice

artículo científico publicado en 2019

Teaching an old drug new tricks: can paroxetine ease the burden of cardiovascular disease in diabetes?

artículo científico publicado en 2013

The S100A6 calcium-binding protein regulates endothelial cell-cycle progression and senescence

artículo científico publicado en 2012

The association between saphenous vein endothelial function, systemic inflammation, and statin therapy in patients undergoing coronary artery bypass surgery

artículo científico publicado en 2007

The impact of insulin resistance on endothelial function, progenitor cells and repair

artículo científico publicado en 2007

The insulin like growth factor and binding protein family: Novel therapeutic targets in obesity & diabetes ⬇️

artículo científico publicado en 2018

The insulin-like growth factor-1 receptor is a negative regulator of nitric oxide bioavailability and insulin sensitivity in the endothelium

scientific journal article

The role of IGF-I and its binding proteins in the development of type 2 diabetes and cardiovascular disease

artículo científico publicado en 2008

Three-year clinical outcome with the Endeavor™ zotarolimus-eluting stent in primary percutaneous coronary intervention for ST elevation myocardial infarction: the Endeavor™ primary PCI study (E-PPCI).

artículo científico publicado en 2011

Tpl2 is required for VEGF-A-stimulated signal transduction and endothelial cell function.

artículo científico publicado en 2019

Transcoronary pacing to assess myocardial viability prior to percutaneous coronary intervention: Pilot study to assess feasibility

artículo científico publicado en 2017

Ubiquitination of basal VEGFR2 regulates signal transduction and endothelial function ⬇️

artículo científico publicado en 2017

VEGF-A isoform-specific regulation of calcium ion flux, transcriptional activation and endothelial cell migration ⬇️

artículo científico publicado en 2015

VEGF-A isoforms differentially regulate ATF-2-dependent VCAM-1 gene expression and endothelial-leukocyte interactions ⬇️

artículo científico publicado en 2014

VEGF-A isoforms program differential VEGFR2 signal transduction, trafficking and proteolysis ⬇️

artículo científico publicado en 2016

VEGFR2 Trafficking, Signaling and Proteolysis is Regulated by the Ubiquitin Isopeptidase USP8. ⬇️

artículo científico publicado en 2015

Vascular endothelial function and blood pressure homeostasis in mice overexpressing IGF binding protein-1.

artículo científico publicado en 2003

Vascular endothelial growth factor A-stimulated signaling from endosomes in primary endothelial cells. ⬇️

artículo científico publicado en 2014

Vascular endothelial growth factors: multitasking functionality in metabolism, health and disease

artículo científico

Vascular insulin-like growth factor-I resistance and diet-induced obesity

artículo científico publicado en 2009

Lista de obras de Stephen Wheatcroft

173 Insulin-like growth factor binding protein 2 (igfbp2): a positive regulator of angiogenesis?

232 Endothelial ship2 knockout causes nox2 nadph oxidase-dependent oxidative stress and endothelial dysfunction

26 Effect of Age and Gender on Outcomes Following Primary Percutaneous Coronary Intervention for ST-elevation Myocardial Infarction in a UK Tertiary Centre

33 Influence of ethnicity on outcomes in primary percutaneous coronary intervention for ST-elevation myocardial infarction

A heat-shock protein axis regulates VEGFR2 proteolysis, blood vessel development and repair

Accelerated endothelial dysfunction in mild prediabetic insulin resistance: the early role of reactive oxygen species.

Acute and one year clinical outcomes following implantation of bioresorbable vascular scaffolds: the ABSORB UK Registry

Ankle pressures in UK South Asians with diabetes mellitus: a case control study

Assessing Coronary Blood Flow Physiology in the Cardiac Catheterisation Laboratory ⬇️

Association of diabetes with increased all-cause mortality following primary percutaneous coronary intervention for ST-segment elevation myocardial infarction in the contemporary era.

Asymmetric dimethylarginine and reduced nitric oxide bioavailability in young Black African men.

Bilateral endophthalmitis and ARDS complicating group G streptococcal endocarditis

Bivalirudin in patients undergoing primary percutaneous coronary intervention for acute ST-elevation myocardial infarction: outcomes in a large real-world population.

Cardiovascular risk in patients with small and medium abdominal aortic aneurysms, and no history of cardiovascular disease.

Changing characteristics and mode of death associated with chronic heart failure caused by left ventricular systolic dysfunction: a study across therapeutic eras

Clinical and Preclinical Use of LOX-1-Specific Antibodies in Diagnostics and Therapeutics

Clinical outcomes following primary percutaneous coronary intervention for ST-elevation myocardial infarction according to sex and race ⬇️

Detection and Quantification of Vascular Endothelial Growth Factor Receptor Tyrosine Kinases in Primary Human Endothelial Cells.

Diabetes mellitus and mortality after acute coronary syndrome as a first or recurrent cardiovascular event

Diabetes mellitus is associated with adverse prognosis in chronic heart failure of ischaemic and non-ischaemic aetiology

Direct ambulance admission to the cardiac catheterization laboratory significantly reduces door-to-balloon times in primary percutaneous coronary intervention.

Diurnal variation in vascular and metabolic function in diet-induced obesity: divergence of insulin resistance and loss of clock rhythm

Does routine pressure wire assessment influence management strategy at coronary angiography for diagnosis of chest pain?: the RIPCORD study

Effect of endothelium-specific insulin resistance on endothelial function in vivo

Effects of insulin resistance on endothelial progenitor cells and vascular repair

Endothelial IGF-1 Receptor Signalling in Diabetes and Insulin Resistance

Endothelial Insulin Receptor Restoration Rescues Vascular Function in Male Insulin Receptor Haploinsufficient Mice ⬇️

Endothelial function and weight loss in obese humans

Endothelium-specific insulin resistance leads to accelerated atherosclerosis in areas with disturbed flow patterns: a role for reactive oxygen species

Haploinsufficiency of the insulin-like growth factor-1 receptor enhances endothelial repair and favorably modifies angiogenic progenitor cell phenotype

How We Measure Heart Rate: Does it Matter?

Human exercise-induced circulating progenitor cell mobilization is nitric oxide-dependent and is blunted in South Asian men.

Hyperglycaemia, in relation to sex, and mortality after acute coronary syndrome

IGF-binding protein-2 protects against the development of obesity and insulin resistance

IGF-dependent and IGF-independent actions of IGF-binding protein-1 and -2: implications for metabolic homeostasis

IGFBP-1 in Cardiometabolic Pathophysiology-Insights From Loss-of-Function and Gain-of-Function Studies in Male Mice

In silico design and biological evaluation of a dual specificity kinase inhibitor targeting cell cycle progression and angiogenesis ⬇️

Increasing circulating IGFBP1 levels improves insulin sensitivity, promotes nitric oxide production, lowers blood pressure, and protects against atherosclerosis

Inducible nitric oxide synthase has divergent effects on vascular and metabolic function in obesity

Inhibition of plasmin-mediated TAFI activation may affect development but not progression of abdominal aortic aneurysms ⬇️

Insulin resistance and endothelial cell dysfunction: studies in mammalian models

Insulin resistance impairs circulating angiogenic progenitor cell function and delays endothelial regeneration ⬇️

Insulin-Like Growth Factor Binding Protein 1 Could Improve Glucose Regulation and Insulin Sensitivity Through Its RGD Domain

Insulinlike Growth Factor-Binding Protein-1 Improves Vascular Endothelial Repair in Male Mice in the Setting of Insulin Resistance ⬇️

Inter-subject differences in constitutive expression levels of the clock gene in man.

Life-threatening coronary artery spasm following sirolimus-eluting stent deployment

Novel role of the IGF-1 receptor in endothelial function and repair: studies in endothelium-targeted IGF-1 receptor transgenic mice ⬇️

Nox2 NADPH oxidase has a critical role in insulin resistance-related endothelial cell dysfunction

OBTAIN: a study of the occurrence of bleeding and thrombosis during anti-platelet therapy in non-cardiac surgery.

Opposing roles of p47phox in basal versus angiotensin II-stimulated alterations in vascular O2- production, vascular tone, and mitogen-activated protein kinase activation

Oxidized LDL activates blood platelets through CD36/NOX2-mediated inhibition of the cGMP/protein kinase G signaling cascade ⬇️

Piezo1 channels sense whole body physical activity to reset cardiovascular homeostasis and enhance performance ⬇️

Pregnenolone sulphate- and cholesterol-regulated TRPM3 channels coupled to vascular smooth muscle secretion and contraction

Preservation of vascular endothelial repair in mice with diet-induced obesity

Preserved glucoregulation but attenuation of the vascular actions of insulin in mice heterozygous for knockout of the insulin receptor

Real-world outcome from ST elevation myocardial infarction in the very elderly before and after the introduction of a 24/7 primary percutaneous coronary intervention service.

Reply to: "Zimarino M et al. The adequacy of myocardial revascularization in patients with multivessel coronary artery disease".

Restoring Akt1 activity in outgrowth endothelial cells from South Asian men rescues vascular reparative potential ⬇️

Scavenger receptor structure and function in health and disease ⬇️

Scavenger receptors and their potential as therapeutic targets in the treatment of cardiovascular disease

Selective Enhancement of Insulin Sensitivity in the Endothelium In Vivo Reveals a Novel Proatherosclerotic Signaling Loop ⬇️

Strain-dependent variation in vascular responses to nitric oxide in the isolated murine heart

TRPC5 ion channel permeation promotes weight gain in hypercholesterolaemic mice

Teaching an old drug new tricks: can paroxetine ease the burden of cardiovascular disease in diabetes?

The S100A6 calcium-binding protein regulates endothelial cell-cycle progression and senescence

The association between saphenous vein endothelial function, systemic inflammation, and statin therapy in patients undergoing coronary artery bypass surgery

The impact of insulin resistance on endothelial function, progenitor cells and repair

The insulin like growth factor and binding protein family: Novel therapeutic targets in obesity & diabetes ⬇️

The insulin-like growth factor-1 receptor is a negative regulator of nitric oxide bioavailability and insulin sensitivity in the endothelium

The role of IGF-I and its binding proteins in the development of type 2 diabetes and cardiovascular disease

Three-year clinical outcome with the Endeavor™ zotarolimus-eluting stent in primary percutaneous coronary intervention for ST elevation myocardial infarction: the Endeavor™ primary PCI study (E-PPCI).

Tpl2 is required for VEGF-A-stimulated signal transduction and endothelial cell function.

Transcoronary pacing to assess myocardial viability prior to percutaneous coronary intervention: Pilot study to assess feasibility

Ubiquitination of basal VEGFR2 regulates signal transduction and endothelial function ⬇️

VEGF-A isoform-specific regulation of calcium ion flux, transcriptional activation and endothelial cell migration ⬇️

VEGF-A isoforms differentially regulate ATF-2-dependent VCAM-1 gene expression and endothelial-leukocyte interactions ⬇️

VEGF-A isoforms program differential VEGFR2 signal transduction, trafficking and proteolysis ⬇️

VEGFR2 Trafficking, Signaling and Proteolysis is Regulated by the Ubiquitin Isopeptidase USP8. ⬇️

Vascular endothelial function and blood pressure homeostasis in mice overexpressing IGF binding protein-1.