Lista de obras - Laura Renkonen-Sinisalo - Dominio Público Uruguay

3'-UTR poly(T/U) repeat of EWSR1 is altered in microsatellite unstable colorectal cancer with nearly perfect sensitivity.

artículo científico publicado en 2015

Association analyses identify 31 new risk loci for colorectal cancer susceptibility

artículo científico publicado en 2019

Associations of Pathogenic Variants in MLH1, MSH2, and MSH6 With Risk of Colorectal Adenomas and Tumors and With Somatic Mutations in Patients With Lynch Syndrome

scientific article published on 08 January 2020

CTCF/cohesin-binding sites are frequently mutated in cancer

artículo científico publicado en 2015

Cancer incidence and survival in Lynch syndrome patients receiving colonoscopic and gynaecological surveillance: first report from the prospective Lynch syndrome database

artículo científico publicado en 2015

Cancer risk and survival in path_MMR carriers by gene and gender up to 75 years of age: a report from the Prospective Lynch Syndrome Database

artículo científico publicado en 2017

Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database

scientific article published on 24 July 2019

Colorectal cancer incidence in path_MLH1 carriers subjected to different follow-up protocols: a Prospective Lynch Syndrome Database report

artículo científico publicado en 2017

Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk

artículo científico publicado en 2012

Comprehensive Evaluation of Protein Coding Mononucleotide Microsatellites in Microsatellite-Unstable Colorectal Cancer

artículo científico publicado en 2017

Comprehensive evaluation of coding region point mutations in microsatellite‐unstable colorectal cancer

artículo científico publicado en 2018

Contribution of allelic imbalance to colorectal cancer

scientific article published in Nature Communications

Converging endometrial and ovarian tumorigenesis in Lynch syndrome: Shared origin of synchronous carcinomas

artículo científico publicado en 2018

Correction: Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database

artículo científico publicado en 2020

DNA hypermethylation appears early and shows increased frequency with dysplasia in Lynch syndrome-associated colorectal adenomas and carcinomas

artículo científico publicado en 2015

DNA methylation changes and somatic mutations as tumorigenic events in Lynch syndrome-associated adenomas retaining mismatch repair protein expression.

artículo científico publicado en 2018

Desmoid tumor patients carry an elevated risk of familial adenomatous polyposis

artículo científico publicado en 2015

Distinct Mutational Profile of Lynch Syndrome Colorectal Cancers Diagnosed under Regular Colonoscopy Surveillance

artículo científico publicado en 2021

Distinct molecular profiles in Lynch syndrome-associated and sporadic ovarian carcinomas

artículo científico publicado en 2013

Eleven candidate susceptibility genes for common familial colorectal cancer

artículo científico publicado en 2013

Epigenetic analysis of sporadic and Lynch-associated ovarian cancers reveals histology-specific patterns of DNA methylation

artículo científico publicado en 2014

Exome and immune cell score analyses reveal great variation within synchronous primary colorectal cancers

scientific article published on 21 March 2019

Exome sequencing in diagnostic evaluation of colorectal cancer predisposition in young patients

artículo científico publicado en 2013

Exome sequencing reveals frequent inactivating mutations in ARID1A, ARID1B, ARID2 and ARID4A in microsatellite unstable colorectal cancer

artículo científico publicado en 2014

Genetic and Epigenetic Characteristics of Inflammatory Bowel Disease–Associated Colorectal Cancer

artículo científico publicado en 2021

Genome-wide association study and meta-analysis in Northern European populations replicate multiple colorectal cancer risk loci

artículo científico publicado en 2017

Identification of candidate oncogenes in human colorectal cancers with microsatellite instability

artículo científico publicado en 2013

Incidence of and survival after subsequent cancers in carriers of pathogenic MMR variants with previous cancer: a report from the prospective Lynch syndrome database

artículo científico publicado en 2016

Lack of association between screening interval and cancer stage in Lynch syndrome may be accounted for by over-diagnosis; a prospective Lynch syndrome database report

scientific article published on 28 February 2019

Low anterior resection combined with a covering stoma in the treatment of rectal cancer reduces the risk of permanent anastomotic failure

artículo científico publicado en 2015

Mendelian randomisation analysis strongly implicates adiposity with risk of developing colorectal cancer

artículo científico publicado en 2016

Mendelian randomisation implicates hyperlipidaemia as a risk factor for colorectal cancer

artículo científico publicado en 2017

Molecular Analysis of Endometrial Tumorigenesis: Importance of Complex Hyperplasia Regardless of Atypia

article

Molecular changes preceding endometrial and ovarian cancer: a study of consecutive endometrial specimens from Lynch syndrome surveillance

artículo científico publicado en 2018

No Difference in Colorectal Cancer Incidence or Stage at Detection by Colonoscopy Among 3 Countries With Different Lynch Syndrome Surveillance Policies

artículo científico publicado en 2018

No Difference in Penetrance between Truncating and Missense/Aberrant Splicing Pathogenic Variants in and : A Prospective Lynch Syndrome Database Study

artículo científico publicado en 2021

Pattern of rectal cancer recurrence after curative surgery

artículo científico publicado en 2015

Pro-inflammatory fatty acid profile and colorectal cancer risk: A Mendelian randomisation analysis

artículo científico publicado en 2017

Retrotransposon insertions can initiate colorectal cancer and are associated with poor survival

artículo científico publicado en 2019

Revised guidelines for the clinical management of Lynch syndrome (HNPCC): recommendations by a group of European experts

artículo científico publicado en 2013

Risk-reducing hysterectomy and bilateral salpingo-oophorectomy in female heterozygotes of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report

artículo científico publicado en 2020

Subtotal Colectomy for Colon Cancer Reduces the Need for Subsequent Surgery in Lynch Syndrome

artículo científico publicado en 2017

Surveillance for endometrial cancer in hereditary nonpolyposis colorectal cancer syndrome

artículo científico publicado en 2007

Survival by colon cancer stage and screening interval in Lynch syndrome: a prospective Lynch syndrome database report

scientific article published on 14 October 2019

Systematic search for rare variants in Finnish early-onset colorectal cancer patients

artículo científico publicado en 2014

Ten Years After Mutation Testing for Lynch Syndrome: Cancer Incidence and Outcome in Mutation-Positive and Mutation-Negative Family Members

scientific article published on 31 August 2009

Uptake of hysterectomy and bilateral salpingo-oophorectomy in carriers of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report

artículo científico publicado en 2021

Variation at 2q35 (PNKD and TMBIM1) influences colorectal cancer risk and identifies a pleiotropic effect with inflammatory bowel disease

artículo científico publicado en 2016

Lista de obras de Laura Renkonen-Sinisalo

3'-UTR poly(T/U) repeat of EWSR1 is altered in microsatellite unstable colorectal cancer with nearly perfect sensitivity.

Association analyses identify 31 new risk loci for colorectal cancer susceptibility

Associations of Pathogenic Variants in MLH1, MSH2, and MSH6 With Risk of Colorectal Adenomas and Tumors and With Somatic Mutations in Patients With Lynch Syndrome

CTCF/cohesin-binding sites are frequently mutated in cancer

Cancer incidence and survival in Lynch syndrome patients receiving colonoscopic and gynaecological surveillance: first report from the prospective Lynch syndrome database

Cancer risk and survival in path_MMR carriers by gene and gender up to 75 years of age: a report from the Prospective Lynch Syndrome Database

Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database

Colorectal cancer incidence in path_MLH1 carriers subjected to different follow-up protocols: a Prospective Lynch Syndrome Database report

Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk

Comprehensive Evaluation of Protein Coding Mononucleotide Microsatellites in Microsatellite-Unstable Colorectal Cancer

Comprehensive evaluation of coding region point mutations in microsatellite‐unstable colorectal cancer

Contribution of allelic imbalance to colorectal cancer

Converging endometrial and ovarian tumorigenesis in Lynch syndrome: Shared origin of synchronous carcinomas

Correction: Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database

DNA hypermethylation appears early and shows increased frequency with dysplasia in Lynch syndrome-associated colorectal adenomas and carcinomas

DNA methylation changes and somatic mutations as tumorigenic events in Lynch syndrome-associated adenomas retaining mismatch repair protein expression.

Desmoid tumor patients carry an elevated risk of familial adenomatous polyposis

Distinct Mutational Profile of Lynch Syndrome Colorectal Cancers Diagnosed under Regular Colonoscopy Surveillance

Distinct molecular profiles in Lynch syndrome-associated and sporadic ovarian carcinomas

Eleven candidate susceptibility genes for common familial colorectal cancer

Epigenetic analysis of sporadic and Lynch-associated ovarian cancers reveals histology-specific patterns of DNA methylation

Exome and immune cell score analyses reveal great variation within synchronous primary colorectal cancers

Exome sequencing in diagnostic evaluation of colorectal cancer predisposition in young patients

Exome sequencing reveals frequent inactivating mutations in ARID1A, ARID1B, ARID2 and ARID4A in microsatellite unstable colorectal cancer

Genetic and Epigenetic Characteristics of Inflammatory Bowel Disease–Associated Colorectal Cancer

Genome-wide association study and meta-analysis in Northern European populations replicate multiple colorectal cancer risk loci

Identification of candidate oncogenes in human colorectal cancers with microsatellite instability

Incidence of and survival after subsequent cancers in carriers of pathogenic MMR variants with previous cancer: a report from the prospective Lynch syndrome database

Lack of association between screening interval and cancer stage in Lynch syndrome may be accounted for by over-diagnosis; a prospective Lynch syndrome database report

Low anterior resection combined with a covering stoma in the treatment of rectal cancer reduces the risk of permanent anastomotic failure

Mendelian randomisation analysis strongly implicates adiposity with risk of developing colorectal cancer

Mendelian randomisation implicates hyperlipidaemia as a risk factor for colorectal cancer

Molecular Analysis of Endometrial Tumorigenesis: Importance of Complex Hyperplasia Regardless of Atypia

Molecular changes preceding endometrial and ovarian cancer: a study of consecutive endometrial specimens from Lynch syndrome surveillance

No Difference in Colorectal Cancer Incidence or Stage at Detection by Colonoscopy Among 3 Countries With Different Lynch Syndrome Surveillance Policies

No Difference in Penetrance between Truncating and Missense/Aberrant Splicing Pathogenic Variants in and : A Prospective Lynch Syndrome Database Study

Pattern of rectal cancer recurrence after curative surgery

Pro-inflammatory fatty acid profile and colorectal cancer risk: A Mendelian randomisation analysis

Retrotransposon insertions can initiate colorectal cancer and are associated with poor survival

Revised guidelines for the clinical management of Lynch syndrome (HNPCC): recommendations by a group of European experts

Risk-reducing hysterectomy and bilateral salpingo-oophorectomy in female heterozygotes of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report

Subtotal Colectomy for Colon Cancer Reduces the Need for Subsequent Surgery in Lynch Syndrome

Surveillance for endometrial cancer in hereditary nonpolyposis colorectal cancer syndrome

Survival by colon cancer stage and screening interval in Lynch syndrome: a prospective Lynch syndrome database report

Systematic search for rare variants in Finnish early-onset colorectal cancer patients

Ten Years After Mutation Testing for Lynch Syndrome: Cancer Incidence and Outcome in Mutation-Positive and Mutation-Negative Family Members

Uptake of hysterectomy and bilateral salpingo-oophorectomy in carriers of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report

Variation at 2q35 (PNKD and TMBIM1) influences colorectal cancer risk and identifies a pleiotropic effect with inflammatory bowel disease

[Diagnosis and treatment of Lynch syndrome]