Lista de obras - Bharath Srinivasan - Dominio Público Uruguay

Allosteric regulation and substrate activation in cytosolic nucleotidase II fromLegionella pneumophila

artículo científico publicado en 2014

Catalytic and substrate promiscuity: distinct multiple chemistries catalysed by the phosphatase domain of receptor protein tyrosine phosphatase.

artículo científico publicado en 2016

Chemical space of Escherichia coli dihydrofolate reductase inhibitors: New approaches for discovering novel drugs for old bugs

artículo científico publicado en 2018

Design, synthesis of novel furan appended benzothiazepine derivatives and in vitro biological evaluation as potent VRV-PL-8a and H+/K+ ATPase inhibitors

artículo científico publicado en 2017

Elucidation of the substrate specificity, kinetic and catalytic mechanism of adenylosuccinate lyase from Plasmodium falciparum

artículo científico publicado en 2009

Experimental validation of FINDSITE(comb) virtual ligand screening results for eight proteins yields novel nanomolar and micromolar binders

artículo científico publicado en 2014

Ligand binding studies, preliminary structure-activity relationship and detailed mechanistic characterization of 1-phenyl-6,6-dimethyl-1,3,5-triazine-2,4-diamine derivatives as inhibitors of Escherichia coli dihydrofolate reductase

artículo científico publicado en 2015

Novel small molecule binders of human N-glycanase 1, a key player in the endoplasmic reticulum associated degradation pathway

artículo científico publicado en 2016

On the importance of composite protein multiple ligand interactions in protein pockets

artículo científico publicado en 2016

Pocket detection and interaction-weighted ligand-similarity search yields novel high-affinity binders for Myocilin-OLF, a protein implicated in glaucoma

artículo científico publicado en 2017

Prediction of substrate specificity and preliminary kinetic characterization of the hypothetical protein PVX_123945 from Plasmodium vivax

artículo científico publicado en 2015

Rational Design of Novel Allosteric Dihydrofolate Reductase Inhibitors Showing Antibacterial Effects on Drug-Resistant Escherichia coli Escape Variants

artículo científico publicado en 2017

Resurrecting the phoenix: When an assay fails

scientific article published on 13 April 2020

Structure and catalytic regulation of Plasmodium falciparum IMP specific nucleotidase

artículo científico publicado en 2020

Synthesis of lignan conjugates via cyclopropanation: Antimicrobial and antioxidant studies

artículo científico publicado en 2016

Synthesis of novel 2-pyrazoline analogues with potent anti-inflammatory effect mediated by inhibition of phospholipase A2: Crystallographic, in silico docking and QSAR analysis.

artículo científico publicado en 2017

Synthesis of novel coumarin appended bis(formylpyrazole) derivatives: Studies on their antimicrobial and antioxidant activities

artículo científico publicado en 2015

Words of advice: teaching enzyme kinetics

artículo científico publicado en 2020

Lista de obras de Bharath Srinivasan

Allosteric regulation and substrate activation in cytosolic nucleotidase II fromLegionella pneumophila

Catalytic and substrate promiscuity: distinct multiple chemistries catalysed by the phosphatase domain of receptor protein tyrosine phosphatase.

Chemical space of Escherichia coli dihydrofolate reductase inhibitors: New approaches for discovering novel drugs for old bugs

Design, synthesis of novel furan appended benzothiazepine derivatives and in vitro biological evaluation as potent VRV-PL-8a and H+/K+ ATPase inhibitors

Elucidation of the substrate specificity, kinetic and catalytic mechanism of adenylosuccinate lyase from Plasmodium falciparum

Experimental validation of FINDSITE(comb) virtual ligand screening results for eight proteins yields novel nanomolar and micromolar binders

Ligand binding studies, preliminary structure-activity relationship and detailed mechanistic characterization of 1-phenyl-6,6-dimethyl-1,3,5-triazine-2,4-diamine derivatives as inhibitors of Escherichia coli dihydrofolate reductase

Novel small molecule binders of human N-glycanase 1, a key player in the endoplasmic reticulum associated degradation pathway

On the importance of composite protein multiple ligand interactions in protein pockets

Pocket detection and interaction-weighted ligand-similarity search yields novel high-affinity binders for Myocilin-OLF, a protein implicated in glaucoma

Prediction of substrate specificity and preliminary kinetic characterization of the hypothetical protein PVX_123945 from Plasmodium vivax

Rational Design of Novel Allosteric Dihydrofolate Reductase Inhibitors Showing Antibacterial Effects on Drug-Resistant Escherichia coli Escape Variants

Resurrecting the phoenix: When an assay fails

Structure and catalytic regulation of Plasmodium falciparum IMP specific nucleotidase

Synthesis of lignan conjugates via cyclopropanation: Antimicrobial and antioxidant studies

Synthesis of novel 2-pyrazoline analogues with potent anti-inflammatory effect mediated by inhibition of phospholipase A2: Crystallographic, in silico docking and QSAR analysis.

Synthesis of novel coumarin appended bis(formylpyrazole) derivatives: Studies on their antimicrobial and antioxidant activities

Words of advice: teaching enzyme kinetics