Lista de obras - Andreas Rummel - Dominio Público Uruguay

A camelid single-domain antibody neutralizes botulinum neurotoxin A by blocking host receptor binding.

artículo científico publicado en 2017

A lipid-binding loop of botulinum neurotoxin serotypes B, DC and G is an essential feature to confer their exquisite potency

artículo científico publicado en 2018

A viral-fusion-peptide-like molecular switch drives membrane insertion of botulinum neurotoxin A1

artículo científico publicado en 2018

Activation of metabotropic GABA receptors increases the energy barrier for vesicle fusion

artículo científico publicado en 2011

Arg(362) and Tyr(365) of the botulinum neurotoxin type a light chain are involved in transition state stabilization

artículo científico publicado en 2002

Bioluminescence assay for the highly sensitive detection of botulinum neurotoxin A activity ⬇️

artículo científico publicado el 21 de octubre de 2013

BoNT/AB hybrid maintains similar duration of paresis as BoNT/A wild-type in murine running wheel assay

artículo científico publicado en 2016

Botulinum Neurotoxin F Subtypes Cleaving the VAMP-2 Q⁻K Peptide Bond Exhibit Unique Catalytic Properties and Substrate Specificities

artículo científico publicado en 2018

Botulinum Neurotoxin Is Shielded by NTNHA in an Interlocked Complex

artículo científico publicado en 2012

Botulinum Neurotoxin Serotype A Recognizes Its Protein Receptor SV2 by a Different Mechanism than Botulinum Neurotoxin B Synaptotagmin

artículo científico publicado en 2016

Botulinum Neurotoxins: Qualitative and Quantitative Analysis Using the Mouse Phrenic Nerve Hemidiaphragm Assay (MPN)

artículo científico publicado en 2015

Botulinum neurotoxin B recognizes its protein receptor with high affinity and specificity

artículo científico publicado en 2006

Botulinum neurotoxin C mutants reveal different effects of syntaxin or SNAP-25 proteolysis on neuromuscular transmission.

artículo científico publicado en 2017

Botulinum neurotoxin G binds synaptotagmin-II in a mode similar to that of serotype B: tyrosine 1186 and lysine 1191 cause its lower affinity

artículo científico publicado en 2013

Botulinum neurotoxin serotype D attacks neurons via two carbohydrate-binding sites in a ganglioside-dependent manner

artículo científico publicado en 2010

Botulinum neurotoxin type D enables cytosolic delivery of enzymatically active cargo proteins to neurones via unfolded translocation intermediates

artículo científico publicado en 2004

Botulinum neurotoxins C, E and F bind gangliosides via a conserved binding site prior to stimulation-dependent uptake with botulinum neurotoxin F utilising the three isoforms of SV2 as second receptor

artículo científico publicado en 2009

Cell entry strategy of clostridial neurotoxins

artículo científico publicado en 2009

Clostridium difficile toxin B inhibits the secretory response of human mast cell line-1 (HMC-1) cells stimulated with high free-Ca²⁺ and GTPγS.

artículo científico publicado en 2014

Crystal Structure of the Receptor-Binding Domain of Botulinum Neurotoxin Type HA, Also Known as Type FA or H.

artículo científico publicado en 2017

Detection, differentiation, and identification of botulinum neurotoxin serotypes C, CD, D, and DC by highly specific immunoassays and mass spectrometry.

artículo científico publicado en 2016

Double Receptor Anchorage of Botulinum Neurotoxins Accounts for their Exquisite Neurospecificity ⬇️

artículo científico publicado el 1 de enero de 2013

Draft Genome Sequence of Bivalent Clostridium botulinum Strain IBCA10-7060, Encoding Botulinum Neurotoxin B and a New FA Mosaic Type

artículo científico publicado en 2014

Exchange of the H(CC) domain mediating double receptor recognition improves the pharmacodynamic properties of botulinum neurotoxin

artículo científico publicado en 2011

Exchanging the minimal cell binding fragments of tetanus neurotoxin in botulinum neurotoxin A and B impacts their toxicity at the neuromuscular junction and central neurons

artículo científico publicado en 2013

Functional detection of botulinum neurotoxin serotypes A to F by monoclonal neoepitope-specific antibodies and suspension array technology

scientific article published on 02 April 2019

Generation and Characterization of Six Recombinant Botulinum Neurotoxins as Reference Material to Serve in an International Proficiency Test

artículo científico publicado en 2015

High-resolution crystal structure of HA33 of botulinum neurotoxin type B progenitor toxin complex

artículo científico publicado en 2014

Historical Perspectives and Guidelines for Botulinum Neurotoxin Subtype Nomenclature.

artículo científico publicado en 2017

Human mast cell line-1 (HMC-1) cells exhibit a membrane capacitance increase when dialysed with high free-Ca(2+) and GTPγS containing intracellular solution

artículo científico publicado en 2013

Human synaptotagmin-II is not a high affinity receptor for botulinum neurotoxin B and G: increased therapeutic dosage and immunogenicity

scientific journal article

Identification of the SV2 protein receptor-binding site of botulinum neurotoxin type E.

artículo científico publicado en 2013

Identification of the protein receptor binding site of botulinum neurotoxins B and G proves the double-receptor concept.

artículo científico publicado en 2006

Identification of the synaptic vesicle glycoprotein 2 receptor binding site in botulinum neurotoxin A

scientific journal article

Inhibiting oral intoxication of botulinum neurotoxin A complex by carbohydrate receptor mimics.

artículo científico publicado en 2015

Innovative and Highly Sensitive Detection of Enterotoxin Based on Receptor Interaction and Monoclonal Antibodies

artículo científico publicado en 2021

Isolation and functional characterization of the novel Clostridium botulinum neurotoxin A8 subtype.

artículo científico publicado en 2015

Medical aspects of toxin weapons.

artículo científico publicado en 2005

Molecular basis for disruption of E-cadherin adhesion by botulinum neurotoxin A complex

artículo científico publicado en 2014

N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A.

artículo científico publicado en 2016

Neutralisation of specific surface carboxylates speeds up translocation of botulinum neurotoxin type B enzymatic domain.

artículo científico publicado en 2013

Only the complex N559-glycan in the synaptic vesicle glycoprotein 2C mediates high affinity binding to botulinum neurotoxin serotype A1.

artículo científico publicado en 2016

Optimization of SNAP-25 and VAMP-2 Cleavage by Botulinum Neurotoxin Serotypes A-F Employing Taguchi Design-of-Experiments

artículo científico publicado en 2019

Preface Biological Toxins—Ancient Molecules Posing a Current Threat.

artículo científico publicado en 2015

Qualitative and Quantitative Detection of Botulinum Neurotoxins from Complex Matrices: Results of the First International Proficiency Test.

artículo científico publicado en 2015

Receptor and substrate interactions of clostridial neurotoxins

scientific article published on 04 March 2009

SNARE tagging allows stepwise assembly of a multimodular medicinal toxin

artículo científico publicado en 2010

Structural basis of the pH-dependent assembly of a botulinum neurotoxin complex.

artículo científico publicado en 2014

Structure of a Bimodular Botulinum Neurotoxin Complex Provides Insights into Its Oral Toxicity

artículo científico publicado en 2013

Substrates and Controls for the Quantitative Detection of Active Botulinum Neurotoxin in Protease-Containing Samples ⬇️

artículo científico publicado el 22 de mayo de 2013

Synaptotagmins I and II act as nerve cell receptors for botulinum neurotoxin G.

artículo científico publicado en 2004

The 25 kDa H<sub>CN</sub> Domain of Clostridial Neurotoxins Is Indispensable for Their Neurotoxicity

artículo científico publicado en 2020

The HCC-domain of botulinum neurotoxins A and B exhibits a singular ganglioside binding site displaying serotype specific carbohydrate interaction

artículo científico publicado en 2004

The biological activity of botulinum neurotoxin type C is dependent upon novel types of ganglioside binding sites

artículo científico publicado en 2011

The long journey of botulinum neurotoxins into the synapse

artículo científico

The synaptic vesicle protein 2C mediates the uptake of botulinum neurotoxin A into phrenic nerves

scientific journal article

Two Feet on the Membrane: Uptake of Clostridial Neurotoxins

artículo científico publicado en 2016

Two carbohydrate binding sites in the H(CC)-domain of tetanus neurotoxin are required for toxicity

artículo científico publicado en 2003

Lista de obras de Andreas Rummel

A camelid single-domain antibody neutralizes botulinum neurotoxin A by blocking host receptor binding.

A lipid-binding loop of botulinum neurotoxin serotypes B, DC and G is an essential feature to confer their exquisite potency

A viral-fusion-peptide-like molecular switch drives membrane insertion of botulinum neurotoxin A1

Activation of metabotropic GABA receptors increases the energy barrier for vesicle fusion

Arg(362) and Tyr(365) of the botulinum neurotoxin type a light chain are involved in transition state stabilization

Bioluminescence assay for the highly sensitive detection of botulinum neurotoxin A activity ⬇️

BoNT/AB hybrid maintains similar duration of paresis as BoNT/A wild-type in murine running wheel assay

Botulinum Neurotoxin F Subtypes Cleaving the VAMP-2 Q⁻K Peptide Bond Exhibit Unique Catalytic Properties and Substrate Specificities

Botulinum Neurotoxin Is Shielded by NTNHA in an Interlocked Complex

Botulinum Neurotoxin Serotype A Recognizes Its Protein Receptor SV2 by a Different Mechanism than Botulinum Neurotoxin B Synaptotagmin

Botulinum Neurotoxins: Qualitative and Quantitative Analysis Using the Mouse Phrenic Nerve Hemidiaphragm Assay (MPN)

Botulinum neurotoxin B recognizes its protein receptor with high affinity and specificity

Botulinum neurotoxin C mutants reveal different effects of syntaxin or SNAP-25 proteolysis on neuromuscular transmission.

Botulinum neurotoxin G binds synaptotagmin-II in a mode similar to that of serotype B: tyrosine 1186 and lysine 1191 cause its lower affinity

Botulinum neurotoxin serotype D attacks neurons via two carbohydrate-binding sites in a ganglioside-dependent manner

Botulinum neurotoxin type D enables cytosolic delivery of enzymatically active cargo proteins to neurones via unfolded translocation intermediates

Botulinum neurotoxins C, E and F bind gangliosides via a conserved binding site prior to stimulation-dependent uptake with botulinum neurotoxin F utilising the three isoforms of SV2 as second receptor

Cell entry strategy of clostridial neurotoxins

Clostridium difficile toxin B inhibits the secretory response of human mast cell line-1 (HMC-1) cells stimulated with high free-Ca²⁺ and GTPγS.

Crystal Structure of the Receptor-Binding Domain of Botulinum Neurotoxin Type HA, Also Known as Type FA or H.

Detection, differentiation, and identification of botulinum neurotoxin serotypes C, CD, D, and DC by highly specific immunoassays and mass spectrometry.

Double Receptor Anchorage of Botulinum Neurotoxins Accounts for their Exquisite Neurospecificity ⬇️

Draft Genome Sequence of Bivalent Clostridium botulinum Strain IBCA10-7060, Encoding Botulinum Neurotoxin B and a New FA Mosaic Type

Exchange of the H(CC) domain mediating double receptor recognition improves the pharmacodynamic properties of botulinum neurotoxin

Exchanging the minimal cell binding fragments of tetanus neurotoxin in botulinum neurotoxin A and B impacts their toxicity at the neuromuscular junction and central neurons

Functional detection of botulinum neurotoxin serotypes A to F by monoclonal neoepitope-specific antibodies and suspension array technology

Generation and Characterization of Six Recombinant Botulinum Neurotoxins as Reference Material to Serve in an International Proficiency Test

High-resolution crystal structure of HA33 of botulinum neurotoxin type B progenitor toxin complex

Historical Perspectives and Guidelines for Botulinum Neurotoxin Subtype Nomenclature.

Human mast cell line-1 (HMC-1) cells exhibit a membrane capacitance increase when dialysed with high free-Ca(2+) and GTPγS containing intracellular solution

Human synaptotagmin-II is not a high affinity receptor for botulinum neurotoxin B and G: increased therapeutic dosage and immunogenicity

Identification of the SV2 protein receptor-binding site of botulinum neurotoxin type E.

Identification of the protein receptor binding site of botulinum neurotoxins B and G proves the double-receptor concept.

Identification of the synaptic vesicle glycoprotein 2 receptor binding site in botulinum neurotoxin A

Inhibiting oral intoxication of botulinum neurotoxin A complex by carbohydrate receptor mimics.

Innovative and Highly Sensitive Detection of Enterotoxin Based on Receptor Interaction and Monoclonal Antibodies

Isolation and functional characterization of the novel Clostridium botulinum neurotoxin A8 subtype.

Medical aspects of toxin weapons.

Molecular basis for disruption of E-cadherin adhesion by botulinum neurotoxin A complex

N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A.

Neutralisation of specific surface carboxylates speeds up translocation of botulinum neurotoxin type B enzymatic domain.

Only the complex N559-glycan in the synaptic vesicle glycoprotein 2C mediates high affinity binding to botulinum neurotoxin serotype A1.

Optimization of SNAP-25 and VAMP-2 Cleavage by Botulinum Neurotoxin Serotypes A-F Employing Taguchi Design-of-Experiments

Preface Biological Toxins—Ancient Molecules Posing a Current Threat.

Qualitative and Quantitative Detection of Botulinum Neurotoxins from Complex Matrices: Results of the First International Proficiency Test.

Receptor and substrate interactions of clostridial neurotoxins

SNARE tagging allows stepwise assembly of a multimodular medicinal toxin

Structural basis of the pH-dependent assembly of a botulinum neurotoxin complex.

Structure of a Bimodular Botulinum Neurotoxin Complex Provides Insights into Its Oral Toxicity

Substrates and Controls for the Quantitative Detection of Active Botulinum Neurotoxin in Protease-Containing Samples ⬇️

Synaptotagmins I and II act as nerve cell receptors for botulinum neurotoxin G.

The 25 kDa H<sub>CN</sub> Domain of Clostridial Neurotoxins Is Indispensable for Their Neurotoxicity

The HCC-domain of botulinum neurotoxins A and B exhibits a singular ganglioside binding site displaying serotype specific carbohydrate interaction

The biological activity of botulinum neurotoxin type C is dependent upon novel types of ganglioside binding sites

The long journey of botulinum neurotoxins into the synapse

The synaptic vesicle protein 2C mediates the uptake of botulinum neurotoxin A into phrenic nerves

Two Feet on the Membrane: Uptake of Clostridial Neurotoxins

Two carbohydrate binding sites in the H(CC)-domain of tetanus neurotoxin are required for toxicity