Lista de obras - Nicholas J. Hawkins - Dominio Público Uruguay

A correlation of the endoscopic characteristics of colonic laterally spreading tumours with genetic alterations

artículo científico publicado en 2013

Activation of the K-ras oncogene in colorectal neoplasms is associated with decreased apoptosis

scientific article published on 01 March 1997

Adaptive Tutorials Versus Web-Based Resources in Radiology: A Mixed Methods Comparison of Efficacy and Student Engagement.

artículo científico publicado en 2015

Adverse Prognostic Effect of Methylation in Colorectal Cancer Is Reversed by Microsatellite Instability

article

Altered promoter nucleosome positioning is an early event in gene silencing

artículo científico publicado en 2014

Antibody immunity to the HER-2/neu oncogenic protein in patients with colorectal cancer

artículo científico publicado en 1999

Authors' reply

artículo científico publicado en 2006

Biodistribution of filamentous phage-Fab in nude mice

artículo científico publicado en 1999

C-kit mutations in gastrointestinal stromal tumours

artículo científico publicado en 2002

CD103+ intraepithelial lymphocytes—a unique population in microsatellite unstable sporadic colorectal cancer

artículo científico publicado en 2003

Characterisation and clinicopathological correlates of serum anti-p53 antibodies in breast and colon cancer

artículo científico publicado en 1996

Checking the scoreboard: the impact of cancer genetics on clinical practice.

artículo científico publicado en 2001

Cohesin Rad21 Mediates Loss of Heterozygosity and Is Upregulated via Wnt Promoting Transcriptional Dysregulation in Gastrointestinal Tumors

artículo científico publicado en 2014

Colorectal carcinomas arising in the hyperplastic polyposis syndrome progress through the chromosomal instability pathway

artículo científico publicado en 2000

Cytokine-Mediated Induction of HLA Antigen Expression on Human Glomerular Mesangial Cells

artículo científico publicado en 1994

Detection of K-ras point mutation by enriched PCR-colorimetric plate assay.

artículo científico

Detection of allelic imbalance in MLH1 expression by pyrosequencing serves as a tool for the identification of germline defects in Lynch syndrome

artículo científico publicado en 2010

Developmentally-regulated expression of murine K-ras isoforms

artículo científico publicado en 1997

Different APC genotypes in proximal and distal sporadic colorectal cancers suggest distinct WNT/β-catenin signalling thresholds for tumourigenesis.

artículo científico publicado en 2012

Disruption of a -35 kb Enhancer Impairs CTCF Binding and Expression in Colorectal Cells

artículo científico publicado en 2018

Does MSI-low exist?

artículo científico publicado en 2002

Epigenetic inactivation of a cluster of genes flanking MLH1 in microsatellite-unstable colorectal cancer

artículo científico publicado en 2007

Epigenetic inactivation of the candidate tumor suppressor USP44 is a frequent and early event in colorectal neoplasia

artículo científico publicado en 2014

Evaluation of different lymphoid tissue sources for the construction of human immunoglobulin gene libraries

artículo científico publicado en 1997

Expression of the novel Wnt receptor ROR2 is increased in breast cancer and may regulate both β-catenin dependent and independent Wnt signalling.

artículo científico publicado en 2014

Germline epimutations of APC are not associated with inherited colorectal polyposis

artículo científico publicado en 2006

Histopathological and clinical evaluation of serrated adenomas of the colon and rectum

artículo científico publicado en 2003

Immunohistochemistry for PMS2 and MSH6 alone can replace a four antibody panel for mismatch repair deficiency screening in colorectal adenocarcinoma

artículo científico publicado en 2011

Impact of microsatellite testing and mismatch repair protein expression on the clinical interpretation of genetic testing in hereditary non-polyposis colorectal cancer

artículo científico publicado en 2002

Implementation of novel pyrosequencing assays to screen for common mutations of BRAF and KRAS in a cohort of sporadic colorectal cancers

artículo científico

Inactivation of p16INK4a by CpG hypermethylation is not a frequent event in colorectal cancer

artículo científico publicado en 2003

Inheritance of a Cancer-AssociatedMLH1Germ-Line Epimutation

artículo científico publicado en 2007

Institutional biobanking: an integral part of contemporary pathology practice

artículo científico publicado en 2015

Introducing research initiatives into healthcare: what do doctors think?

artículo científico publicado en 2014

Kirsten ras mutations in patients with colorectal cancer: the 'RASCAL II' study

artículo científico publicado en 2001

Large-scale delineation of secreted protein biomarkers overexpressed in cancer tissue and serum

artículo científico publicado en 2003

MGMT methylation is associated primarily with the germline C>T SNP (rs16906252) in colorectal cancer and normal colonic mucosa

artículo científico publicado en 2009

MLH1 Germline Epimutations as a Factor in Hereditary Nonpolyposis Colorectal Cancer

article

Methylation of the 3p22 region encompassing MLH1 is representative of the CpG island methylator phenotype in colorectal cancer.

artículo científico publicado en 2010

Microsatellite-stable diploid carcinoma: a biologically distinct and aggressive subset of sporadic colorectal cancer

artículo científico publicado en 2001

Molecular tumour clocks and colorectal cancer: seeing the unseen

artículo científico publicado en 2002

PIK3CA and PTEN gene and exon mutation-specific clinicopathologic and molecular associations in colorectal cancer

artículo científico publicado en 2013

Poor-prognosis estrogen receptor-positive breast cancer identified by histopathologic subclassification

artículo científico publicado en 2008

Population-based molecular screening for Lynch syndrome: implications for personalized medicine

artículo científico publicado en 2013

Progress in gastrointestinal pathology in the genetic era

artículo científico publicado en 2002

Prohibitin expression is associated with high grade breast cancer but is not a driver of amplification at 17q21.33.

artículo científico publicado en 2013

RAD21 cohesin overexpression is a prognostic and predictive marker exacerbating poor prognosis in KRAS mutant colorectal carcinomas.

artículo científico publicado en 2014

Regulation and expression of human Fabs under the control of the Escherichia coli arabinose promoter, PBAD

artículo científico publicado en 1997

Relative Distribution of Folate Species Is Associated with Global DNA Methylation in Human Colorectal Mucosa

article

Retrieval of human antibodies from phage-display libraries using enzymatic cleavage

artículo científico publicado en 1996

Routine testing for mismatch repair deficiency in sporadic colorectal cancer is justified

article

SMAD2, SMAD3 and SMAD4 mutations in colorectal cancer

artículo científico publicado en 2013

Serrated and non-serrated polyps of the colorectum: their prevalence in an unselected case series and correlation of BRAF mutation analysis with the diagnosis of sessile serrated adenoma.

artículo científico publicado en 2009

Single nucleotide polymorphism array profiling identifies distinct chromosomal aberration patterns across colorectal adenomas and carcinomas

artículo científico publicado en 2015

Survival in stage II/III colorectal cancer is independently predicted by chromosomal and microsatellite instability, but not by specific driver mutations

artículo científico publicado en 2013

The CpG Island Methylator Phenotype Is Not Associated with a Personal or Family History of Cancer

article

The Role of hMLH1 Methylation in the Development of Synchronous Sporadic Colorectal Carcinomas

article

The relationship between hypomethylation and CpG island methylation in colorectal neoplasia

artículo científico publicado en 2003

Tolerance of whole-genome doubling propagates chromosomal instability and accelerates cancer genome evolution.

artículo científico publicado en 2014

Unconjugated antibodies for cancer therapy: lessons from the clinic.

artículo científico publicado en 1997

Wild-type APC predicts poor prognosis in microsatellite-stable proximal colon cancer

artículo científico publicado en 2015

Lista de obras de Nicholas J. Hawkins

A correlation of the endoscopic characteristics of colonic laterally spreading tumours with genetic alterations

Activation of the K-ras oncogene in colorectal neoplasms is associated with decreased apoptosis

Adaptive Tutorials Versus Web-Based Resources in Radiology: A Mixed Methods Comparison of Efficacy and Student Engagement.

Adverse Prognostic Effect of Methylation in Colorectal Cancer Is Reversed by Microsatellite Instability

Altered promoter nucleosome positioning is an early event in gene silencing

Antibody immunity to the HER-2/neu oncogenic protein in patients with colorectal cancer

Authors' reply

Biodistribution of filamentous phage-Fab in nude mice

C-kit mutations in gastrointestinal stromal tumours

CD103+ intraepithelial lymphocytes—a unique population in microsatellite unstable sporadic colorectal cancer

Characterisation and clinicopathological correlates of serum anti-p53 antibodies in breast and colon cancer

Checking the scoreboard: the impact of cancer genetics on clinical practice.

Cohesin Rad21 Mediates Loss of Heterozygosity and Is Upregulated via Wnt Promoting Transcriptional Dysregulation in Gastrointestinal Tumors

Colorectal carcinomas arising in the hyperplastic polyposis syndrome progress through the chromosomal instability pathway

Cytokine-Mediated Induction of HLA Antigen Expression on Human Glomerular Mesangial Cells

Detection of K-ras point mutation by enriched PCR-colorimetric plate assay.

Detection of allelic imbalance in MLH1 expression by pyrosequencing serves as a tool for the identification of germline defects in Lynch syndrome

Developmentally-regulated expression of murine K-ras isoforms

Different APC genotypes in proximal and distal sporadic colorectal cancers suggest distinct WNT/β-catenin signalling thresholds for tumourigenesis.

Disruption of a -35 kb Enhancer Impairs CTCF Binding and Expression in Colorectal Cells

Does MSI-low exist?

Epigenetic inactivation of a cluster of genes flanking MLH1 in microsatellite-unstable colorectal cancer

Epigenetic inactivation of the candidate tumor suppressor USP44 is a frequent and early event in colorectal neoplasia

Evaluation of different lymphoid tissue sources for the construction of human immunoglobulin gene libraries

Expression of the novel Wnt receptor ROR2 is increased in breast cancer and may regulate both β-catenin dependent and independent Wnt signalling.

Germline epimutations of APC are not associated with inherited colorectal polyposis

Histopathological and clinical evaluation of serrated adenomas of the colon and rectum

Immunohistochemistry for PMS2 and MSH6 alone can replace a four antibody panel for mismatch repair deficiency screening in colorectal adenocarcinoma

Impact of microsatellite testing and mismatch repair protein expression on the clinical interpretation of genetic testing in hereditary non-polyposis colorectal cancer

Implementation of novel pyrosequencing assays to screen for common mutations of BRAF and KRAS in a cohort of sporadic colorectal cancers

Inactivation of p16INK4a by CpG hypermethylation is not a frequent event in colorectal cancer

Inheritance of a Cancer-AssociatedMLH1Germ-Line Epimutation

Institutional biobanking: an integral part of contemporary pathology practice

Introducing research initiatives into healthcare: what do doctors think?

Kirsten ras mutations in patients with colorectal cancer: the 'RASCAL II' study

Large-scale delineation of secreted protein biomarkers overexpressed in cancer tissue and serum

MGMT methylation is associated primarily with the germline C>T SNP (rs16906252) in colorectal cancer and normal colonic mucosa

MLH1 Germline Epimutations as a Factor in Hereditary Nonpolyposis Colorectal Cancer

Methylation of the 3p22 region encompassing MLH1 is representative of the CpG island methylator phenotype in colorectal cancer.

Microsatellite-stable diploid carcinoma: a biologically distinct and aggressive subset of sporadic colorectal cancer

Molecular tumour clocks and colorectal cancer: seeing the unseen

PIK3CA and PTEN gene and exon mutation-specific clinicopathologic and molecular associations in colorectal cancer

Poor-prognosis estrogen receptor-positive breast cancer identified by histopathologic subclassification

Population-based molecular screening for Lynch syndrome: implications for personalized medicine

Progress in gastrointestinal pathology in the genetic era

Prohibitin expression is associated with high grade breast cancer but is not a driver of amplification at 17q21.33.

RAD21 cohesin overexpression is a prognostic and predictive marker exacerbating poor prognosis in KRAS mutant colorectal carcinomas.

Regulation and expression of human Fabs under the control of the Escherichia coli arabinose promoter, PBAD

Relative Distribution of Folate Species Is Associated with Global DNA Methylation in Human Colorectal Mucosa

Retrieval of human antibodies from phage-display libraries using enzymatic cleavage

Routine testing for mismatch repair deficiency in sporadic colorectal cancer is justified

SMAD2, SMAD3 and SMAD4 mutations in colorectal cancer

Serrated and non-serrated polyps of the colorectum: their prevalence in an unselected case series and correlation of BRAF mutation analysis with the diagnosis of sessile serrated adenoma.

Single nucleotide polymorphism array profiling identifies distinct chromosomal aberration patterns across colorectal adenomas and carcinomas

Survival in stage II/III colorectal cancer is independently predicted by chromosomal and microsatellite instability, but not by specific driver mutations

The CpG Island Methylator Phenotype Is Not Associated with a Personal or Family History of Cancer

The Role of hMLH1 Methylation in the Development of Synchronous Sporadic Colorectal Carcinomas

The relationship between hypomethylation and CpG island methylation in colorectal neoplasia

Tolerance of whole-genome doubling propagates chromosomal instability and accelerates cancer genome evolution.

Unconjugated antibodies for cancer therapy: lessons from the clinic.

Wild-type APC predicts poor prognosis in microsatellite-stable proximal colon cancer