Lista de obras - Jordi Heijman - Dominio Público Uruguay

Acute effects of alcohol on cardiac electrophysiology and arrhythmogenesis: Insights from multiscale in silico analyses

artículo científico publicado en 2020

Angiotensin Receptor-Neprilysin Inhibitor (ARNI) and Cardiac Arrhythmias ⬇️

artículo científico publicado en 2021

Atrial Myocyte NLRP3/CaMKII Nexus Forms a Substrate for Post-Operative Atrial Fibrillation

artículo científico publicado en 2020

Atrial arrhythmogenesis in catecholaminergic polymorphic ventricular tachycardia--is there a mechanistic link between sarcoplasmic reticulum Ca(2+) leak and re-entry?

artículo científico publicado en 2013

Bayesian network analyses in atrial fibrillation - A path to better therapies?

Beta-Adrenergic Receptor Stimulation Modulates the Cellular Proarrhythmic Effects of Chloroquine and Azithromycin

artículo científico publicado en 2020

Calcium Handling Abnormalities as a Target for Atrial Fibrillation Therapeutics: How Close to Clinical Implementation?

artículo científico

Calcium dysregulation in atrial fibrillation: the role of CaMKII

artículo científico publicado en 2014

Calcium handling and atrial fibrillation.

artículo científico

Cardiac safety assays

artículo científico publicado en 2013

Cardiomyocyte calcium handling in health and disease: Insights from in vitro and in silico studies

scientific article published on 15 March 2020

Cellular and molecular electrophysiology of atrial fibrillation initiation, maintenance, and progression

artículo científico publicado en 2014

Cellular and molecular mechanisms of atrial arrhythmogenesis in patients with paroxysmal atrial fibrillation.

artículo científico publicado en 2013

Challenges to the translation of basic science findings to atrial fibrillation therapies

artículo científico publicado en 2016

Chronic loss of inhibitor-1 diminishes cardiac RyR2 phosphorylation despite exaggerated CaMKII activity

artículo científico publicado en 2017

Computational modeling: What does it tell us about atrial fibrillation therapy?

scientific article published on 25 January 2019

Computational models of atrial cellular electrophysiology and calcium handling, and their role in atrial fibrillation.

artículo científico publicado en 2015

Computational models of atrial fibrillation: achievements, challenges, and perspectives for improving clinical care

artículo científico publicado en 2021

Constitutive activity of the acetylcholine-activated potassium current IK,ACh in cardiomyocytes.

artículo científico publicado en 2014

Determinants of beat-to-beat variability of repolarization duration in the canine ventricular myocyte: a computational analysis

artículo científico publicado en 2013

Diastolic spontaneous calcium release from the sarcoplasmic reticulum increases beat-to-beat variability of repolarization in canine ventricular myocytes after β-adrenergic stimulation.

artículo científico publicado en 2012

Differences in Left Versus Right Ventricular Electrophysiological Properties in Cardiac Dysfunction and Arrhythmogenesis

artículo científico publicado en 2016

Dominant-negative control of cAMP-dependent IKs upregulation in human long-QT syndrome type 1.

artículo científico publicado en 2011

Electrical storm: recent pathophysiological insights and therapeutic consequences.

artículo científico

Electrocardiographic characteristics associated with atrial fibrillation - What do they tell us?

artículo científico publicado en 2018

Function and regulation of serine/threonine phosphatases in the healthy and diseased heart.

artículo científico publicado en 2013

Genome-wide association studies of atrial fibrillation: Finding meaning in the life of risk loci

scientific article published on 08 July 2019

German Cardiac Society Working Group on Cellular Electrophysiology state-of-the-art paper: impact of molecular mechanisms on clinical arrhythmia management

article

Highlights from the International Journal of Cardiology Heart & Vasculature: Heart failure, atrial fibrillation, coronary artery disease and myocardial infarction

scientific article published on 20 November 2019

I(Ks) restricts excessive beat-to-beat variability of repolarization during beta-adrenergic receptor stimulation.

artículo científico publicado en 2009

Impaired Na⁺-dependent regulation of acetylcholine-activated inward-rectifier K⁺ current modulates action potential rate dependence in patients with chronic atrial fibrillation.

artículo científico publicado en 2013

Inflammatory signalling in atrial cardiomyocytes: a novel unifying principle in atrial fibrillation pathophysiology

artículo científico publicado en 2022

Inhibition of Small-Conductance Ca2+-Activated K+ Channels: The Long-Awaited Breakthrough for Antiarrhythmic Drug Therapy of Atrial Fibrillation?

artículo científico publicado en 2017

Inositol Trisphosphate Receptors and Nuclear Calcium in Atrial Fibrillation

artículo científico publicado en 2020

Inverse remodelling of K2P3.1 K+ channel expression and action potential duration in left ventricular dysfunction and atrial fibrillation: implications for patient-specific antiarrhythmic drug therapy

artículo científico publicado en 2017

Investigational antiarrhythmic agents: promising drugs in early clinical development.

artículo científico publicado en 2017

Ion channels as part of macromolecular multiprotein complexes : Clinical significance

artículo científico publicado en 2017

Irregular rhythm and atrial metabolism are key for the evolution of proarrhythmic atrial remodeling in atrial fibrillation

scientific article published on 28 May 2015

KCNQ1 autoantibodies: another way to regulate IKs.

artículo científico publicado en 2013

Left atrial activation and asymmetric anatomical remodeling in patients with atrial fibrillation: The relation between anatomy and function

artículo científico publicado en 2020

Local control of β-adrenergic stimulation: Effects on ventricular myocyte electrophysiology and Ca2+-transient ⬇️

artículo científico publicado el 21 de febrero de 2011

Long-QT mutation p.K557E-Kv7.1: dominant-negative suppression of IKs, but preserved cAMP-dependent up-regulation

artículo científico publicado en 2014

Maastricht antiarrhythmic drug evaluator (MANTA): A computational tool for better understanding of antiarrhythmic drugs

scientific article published on 04 September 2019

Molecular Basis of Atrial Fibrillation Pathophysiology and Therapy: A Translational Perspective

artículo científico publicado en 2020

Muscarinic type-1 receptors contribute to IK,ACh in human atrial cardiomyocytes and are upregulated in patients with chronic atrial fibrillation

artículo científico publicado en 2017

New antiarrhythmic targets in atrial fibrillation

artículo científico publicado en 2015

New directions in antiarrhythmic drug therapy for atrial fibrillation

artículo científico

Nucleoside Diphosphate Kinase-C Suppresses cAMP Formation in Human Heart Failure.

artículo científico publicado en 2016

Pleiotropic actions of amiodarone: still puzzling after half a century

artículo científico publicado en 2013

Pleiotropic effects of antiarrhythmic agents: dronedarone in the treatment of atrial fibrillation

artículo científico publicado en 2013

Postoperative atrial fibrillation: mechanisms, manifestations and management

scientific article published on 01 July 2019

Potassium channels in the heart: structure, function and regulation.

artículo científico publicado en 2016

Potassium currents in the heart: functional roles in repolarization, arrhythmia and therapeutics

artículo científico publicado en 2016

Profibrotic, Electrical, and Calcium-Handling Remodeling of the Atria in Heart Failure Patients With and Without Atrial Fibrillation

article by Cristina E Molina et al published 2018 in Frontiers in Physiology

Properties and ionic mechanisms of action potential adaptation, restitution, and accommodation in canine epicardium.

scientific article published on 23 January 2009

Rat engineered heart tissue: a novel tool in the safety pharmacology toolkit?

artículo científico publicado en 2014

Recurrence of atrial fibrillation following non-cardiac surgery or acute illness: A common but rarely detected complication

artículo científico publicado en 2020

Regulation of heterotrimeric G-protein signaling by NDPK/NME proteins and caveolins: an update

artículo científico publicado en 2017

Response to Letter Regarding Article, "Upregulation of K2P3.1 K+ Current Causes Action Potential Shortening in Patients With Chronic Atrial Fibrillation"

scientific article published on 01 March 2016

Resveratrol: an effective pharmacological agent to prevent inflammation-induced atrial fibrillation?

scientific article published on 20 September 2018

Rhythm control of atrial fibrillation in heart failure.

artículo científico publicado en 2013

Serine/Threonine Phosphatases in Atrial Fibrillation

artículo científico publicado en 2017

Stretching the limits of antiarrhythmic drug therapy: The promise of small-conductance calcium-activated potassium channel blockers

artículo científico publicado en 2021

Systems approaches to post-operative atrial fibrillation - do they help us to better understand the ionic basis of the arrhythmogenic substrate?

scientific article published on 21 June 2012

T-wave Right Slope Provides a New Angle in the Prediction of Drug-Induced Ventricular Arrhythmias : Editorial to: "Electrocardiographic Predictors of Torsadogenic Risk During Dofetilide or Sotalol Initiation: Utility of a Novel T Wave Analysis Progr

scientific article published on 01 October 2015

Targeting supraventricular ectopic complexes: Which approach should be used and how does it affect atrial fibrillation?

scientific article published on 01 October 2017

The multiple proarrhythmic roles of cardiac calcium-handling abnormalities: triggered activity, conduction abnormalities, beat-to-beat variability, and adverse remodelling

artículo científico publicado en 2016

The value of basic research insights into atrial fibrillation mechanisms as a guide to therapeutic innovation: a critical analysis

artículo científico publicado en 2015

Tools to Keep the Clock Ticking: Molecular Approaches to Treat Sinus Node Dysfunction

scientific article published on 04 June 2015

Translational Challenges in Atrial Fibrillation

artículo científico publicado en 2018

Upregulation of K(2P)3.1 K+ Current Causes Action Potential Shortening in Patients With Chronic Atrial Fibrillation

artículo científico publicado en 2015

Why translation from basic discoveries to clinical applications is so difficult for atrial fibrillation and possible approaches to improving it ⬇️

artículo científico publicado en 2021

[Cardiovascular pharmacotherapy. Risks and adverse effects]

scientific article published on 01 March 2014

Lista de obras de Jordi Heijman

Acute effects of alcohol on cardiac electrophysiology and arrhythmogenesis: Insights from multiscale in silico analyses

Angiotensin Receptor-Neprilysin Inhibitor (ARNI) and Cardiac Arrhythmias ⬇️

Atrial Myocyte NLRP3/CaMKII Nexus Forms a Substrate for Post-Operative Atrial Fibrillation

Atrial arrhythmogenesis in catecholaminergic polymorphic ventricular tachycardia--is there a mechanistic link between sarcoplasmic reticulum Ca(2+) leak and re-entry?

Bayesian network analyses in atrial fibrillation - A path to better therapies?

Beta-Adrenergic Receptor Stimulation Modulates the Cellular Proarrhythmic Effects of Chloroquine and Azithromycin

Calcium Handling Abnormalities as a Target for Atrial Fibrillation Therapeutics: How Close to Clinical Implementation?

Calcium dysregulation in atrial fibrillation: the role of CaMKII

Calcium handling and atrial fibrillation.

Cardiac safety assays

Cardiomyocyte calcium handling in health and disease: Insights from in vitro and in silico studies

Cellular and molecular electrophysiology of atrial fibrillation initiation, maintenance, and progression

Cellular and molecular mechanisms of atrial arrhythmogenesis in patients with paroxysmal atrial fibrillation.

Challenges to the translation of basic science findings to atrial fibrillation therapies

Chronic loss of inhibitor-1 diminishes cardiac RyR2 phosphorylation despite exaggerated CaMKII activity

Computational modeling: What does it tell us about atrial fibrillation therapy?

Computational models of atrial cellular electrophysiology and calcium handling, and their role in atrial fibrillation.

Computational models of atrial fibrillation: achievements, challenges, and perspectives for improving clinical care

Constitutive activity of the acetylcholine-activated potassium current IK,ACh in cardiomyocytes.

Determinants of beat-to-beat variability of repolarization duration in the canine ventricular myocyte: a computational analysis

Diastolic spontaneous calcium release from the sarcoplasmic reticulum increases beat-to-beat variability of repolarization in canine ventricular myocytes after β-adrenergic stimulation.

Differences in Left Versus Right Ventricular Electrophysiological Properties in Cardiac Dysfunction and Arrhythmogenesis

Dominant-negative control of cAMP-dependent IKs upregulation in human long-QT syndrome type 1.

Electrical storm: recent pathophysiological insights and therapeutic consequences.

Electrocardiographic characteristics associated with atrial fibrillation - What do they tell us?

Function and regulation of serine/threonine phosphatases in the healthy and diseased heart.

Genome-wide association studies of atrial fibrillation: Finding meaning in the life of risk loci

German Cardiac Society Working Group on Cellular Electrophysiology state-of-the-art paper: impact of molecular mechanisms on clinical arrhythmia management

Highlights from the International Journal of Cardiology Heart & Vasculature: Heart failure, atrial fibrillation, coronary artery disease and myocardial infarction

I(Ks) restricts excessive beat-to-beat variability of repolarization during beta-adrenergic receptor stimulation.

Impaired Na⁺-dependent regulation of acetylcholine-activated inward-rectifier K⁺ current modulates action potential rate dependence in patients with chronic atrial fibrillation.

Inflammatory signalling in atrial cardiomyocytes: a novel unifying principle in atrial fibrillation pathophysiology

Inhibition of Small-Conductance Ca2+-Activated K+ Channels: The Long-Awaited Breakthrough for Antiarrhythmic Drug Therapy of Atrial Fibrillation?

Inositol Trisphosphate Receptors and Nuclear Calcium in Atrial Fibrillation

Inverse remodelling of K2P3.1 K+ channel expression and action potential duration in left ventricular dysfunction and atrial fibrillation: implications for patient-specific antiarrhythmic drug therapy

Investigational antiarrhythmic agents: promising drugs in early clinical development.

Ion channels as part of macromolecular multiprotein complexes : Clinical significance

Irregular rhythm and atrial metabolism are key for the evolution of proarrhythmic atrial remodeling in atrial fibrillation

KCNQ1 autoantibodies: another way to regulate IKs.

Left atrial activation and asymmetric anatomical remodeling in patients with atrial fibrillation: The relation between anatomy and function

Local control of β-adrenergic stimulation: Effects on ventricular myocyte electrophysiology and Ca2+-transient ⬇️

Long-QT mutation p.K557E-Kv7.1: dominant-negative suppression of IKs, but preserved cAMP-dependent up-regulation

Maastricht antiarrhythmic drug evaluator (MANTA): A computational tool for better understanding of antiarrhythmic drugs

Molecular Basis of Atrial Fibrillation Pathophysiology and Therapy: A Translational Perspective

Muscarinic type-1 receptors contribute to IK,ACh in human atrial cardiomyocytes and are upregulated in patients with chronic atrial fibrillation

New antiarrhythmic targets in atrial fibrillation

New directions in antiarrhythmic drug therapy for atrial fibrillation

Nucleoside Diphosphate Kinase-C Suppresses cAMP Formation in Human Heart Failure.

Pleiotropic actions of amiodarone: still puzzling after half a century

Pleiotropic effects of antiarrhythmic agents: dronedarone in the treatment of atrial fibrillation

Postoperative atrial fibrillation: mechanisms, manifestations and management

Potassium channels in the heart: structure, function and regulation.

Potassium currents in the heart: functional roles in repolarization, arrhythmia and therapeutics

Profibrotic, Electrical, and Calcium-Handling Remodeling of the Atria in Heart Failure Patients With and Without Atrial Fibrillation

Properties and ionic mechanisms of action potential adaptation, restitution, and accommodation in canine epicardium.

Rat engineered heart tissue: a novel tool in the safety pharmacology toolkit?

Recurrence of atrial fibrillation following non-cardiac surgery or acute illness: A common but rarely detected complication

Regulation of heterotrimeric G-protein signaling by NDPK/NME proteins and caveolins: an update

Response to Letter Regarding Article, "Upregulation of K2P3.1 K+ Current Causes Action Potential Shortening in Patients With Chronic Atrial Fibrillation"

Resveratrol: an effective pharmacological agent to prevent inflammation-induced atrial fibrillation?

Rhythm control of atrial fibrillation in heart failure.

Serine/Threonine Phosphatases in Atrial Fibrillation

Stretching the limits of antiarrhythmic drug therapy: The promise of small-conductance calcium-activated potassium channel blockers

Systems approaches to post-operative atrial fibrillation - do they help us to better understand the ionic basis of the arrhythmogenic substrate?

T-wave Right Slope Provides a New Angle in the Prediction of Drug-Induced Ventricular Arrhythmias : Editorial to: "Electrocardiographic Predictors of Torsadogenic Risk During Dofetilide or Sotalol Initiation: Utility of a Novel T Wave Analysis Progr

Targeting supraventricular ectopic complexes: Which approach should be used and how does it affect atrial fibrillation?

The multiple proarrhythmic roles of cardiac calcium-handling abnormalities: triggered activity, conduction abnormalities, beat-to-beat variability, and adverse remodelling

The value of basic research insights into atrial fibrillation mechanisms as a guide to therapeutic innovation: a critical analysis

Tools to Keep the Clock Ticking: Molecular Approaches to Treat Sinus Node Dysfunction

Translational Challenges in Atrial Fibrillation

Upregulation of K(2P)3.1 K+ Current Causes Action Potential Shortening in Patients With Chronic Atrial Fibrillation

Why translation from basic discoveries to clinical applications is so difficult for atrial fibrillation and possible approaches to improving it ⬇️

[Cardiovascular pharmacotherapy. Risks and adverse effects]